Alexandra R. Lobach, Ph.D.
Affiliations: | 2014 | Pharmaceutical Sciences | University of Toronto, Toronto, ON, Canada |
Area:
Pharmacy, ToxicologyGoogle:
"Alexandra Lobach"Parents
Sign in to add mentor| Jack P. Uetrecht | grad student | 2014 | University of Toronto | |
| (Insights into the Mechanism of Drug-Induced Agranulocytosis: A Study of the Immune Changes Induced by Clozapine and Amodiaquine.) | ||||
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| Sernoskie SC, Lobach AR, Kato R, et al. (2022) Clozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 186: 70-82 |
| Metushi IG, Cai P, Dervovic D, et al. (2015) Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset. Journal of Immunotoxicology. 12: 247-60 |
| Lobach AR, Uetrecht J. (2014) Clozapine promotes the proliferation of granulocyte progenitors in the bone marrow leading to increased granulopoiesis and neutrophilia in rats. Chemical Research in Toxicology. 27: 1109-19 |
| Lobach AR, Uetrecht J. (2014) Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis. Chemical Research in Toxicology. 27: 699-709 |
| Ng W, Lobach AR, Zhu X, et al. (2012) Animal models of idiosyncratic drug reactions. Advances in Pharmacology (San Diego, Calif.). 63: 81-135 |