Youngah Jo, Ph.D.

Affiliations: 
2004 Texas Tech University, Lubbock, TX 
Area:
Cell Biology, Molecular Biology
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"Youngah Jo"

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Douglas M. Stocco grad student 2004 Texas Tech
 (Probing the characteristics of constitutive steroid biosynthesis in R2C Leydig tumor cells.)
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Publications

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Faulkner R, Jo Y. (2022) Synthesis, function, and regulation of sterol and nonsterol isoprenoids. Frontiers in Molecular Biosciences. 9: 1006822
Jo Y, DeBose-Boyd RA. (2022) Post-Translational Regulation of HMG CoA Reductase. Cold Spring Harbor Perspectives in Biology
Elsabrouty R, Jo Y, Hwang S, et al. (2021) Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1. Elife. 10
Jo Y, Kim SS, Garland K, et al. (2020) Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with deficiency. Elife. 9
Jo Y, Hamilton JS, Hwang S, et al. (2019) Schnyder corneal dystrophy-associated UBIAD1 Inhibits ER-associated degradation of HMG CoA reductase in mice. Elife. 8
Hwang S, Nguyen AD, Jo Y, et al. (2017) Hypoxia-inducible factor-1α activates insig-2 transcription for degradation of HMG CoA reductase in the liver. The Journal of Biological Chemistry
Schumacher MM, Jun DJ, Jo Y, et al. (2016) Geranylgeranyl-Regulated Transport of the Prenyltransferase UBIAD1 between Membranes of the ER and Golgi. Journal of Lipid Research
Schumacher MM, Elsabrouty R, Seemann J, et al. (2015) The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase. Elife. 4
Elsabrouty R, Jo Y, Dinh TT, et al. (2013) Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells. Molecular Biology of the Cell. 24: 3300-8
Faulkner RA, Nguyen AD, Jo Y, et al. (2013) Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. Journal of Lipid Research. 54: 1011-22
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