Melissa K. Middleton, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Melissa Middleton"

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Ellen Pure grad student 2006 Penn
 (12/15-lipoxygenase and the myeloid cell: A chronicle of oxidation, inflammation, and leukemogenesis.)
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Publications

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Middleton MK, Zukas AM, Rubinstein T, et al. (2009) 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis. Infection and Immunity. 77: 5690-700
Zhao L, Lee E, Zukas AM, et al. (2008) CD44 expressed on both bone marrow-derived and non-bone marrow-derived cells promotes atherogenesis in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1283-9
Zhao L, Hall JA, Levenkova N, et al. (2007) CD44 regulates vascular gene expression in a proatherogenic environment. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 886-92
Middleton MK, Zukas AM, Rubinstein T, et al. (2006) Identification of 12/15-lipoxygenase as a suppressor of myeloproliferative disease. The Journal of Experimental Medicine. 203: 2529-40
Middleton MK, Rubinstein T, Puré E. (2006) Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15-lipoxygenase. Journal of Immunology (Baltimore, Md. : 1950). 176: 265-74
Ali K, Middleton M, Puré E, et al. (2005) Apolipoprotein E suppresses the type I inflammatory response in vivo. Circulation Research. 97: 922-7
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