Elaine E. Wirrig, Ph.D.

Affiliations: 
2009 Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology
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"Elaine Wirrig"

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Andy Wessels grad student 2009 MUSC
 (Hyaluronan and Proteoglycan Binding Link Proteins (Haplns) in cardiac development.)
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Publications

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Wirrig EE, Gomez MV, Hinton RB, et al. (2015) COX2 inhibition reduces aortic valve calcification in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 938-47
Wirrig E, Yutzey K. (2015) Neural Crest-Derived Valve Interstitial Cells Calcify In The Klotho-Deficient Mouse Model Of Aortic Valve Disease The Faseb Journal. 29
Wirrig EE, Yutzey KE. (2014) Conserved transcriptional regulatory mechanisms in aortic valve development and disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 737-41
Lockhart MM, Wirrig EE, Phelps AL, et al. (2013) Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart. Plos One. 8: e57073
Cheek JD, Wirrig EE, Alfieri CM, et al. (2012) Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease. Journal of Molecular and Cellular Cardiology. 52: 689-700
Lockhart M, Wirrig E, Phelps A, et al. (2011) Extracellular matrix and heart development. Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 535-50
Wirrig EE, Hinton RB, Yutzey KE. (2011) Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. Journal of Molecular and Cellular Cardiology. 50: 561-9
Wirrig EE, Yutzey KE. (2011) Transcriptional regulation of heart valve development and disease. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 20: 162-7
Chakraborty S, Wirrig EE, Hinton RB, et al. (2010) Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves. Developmental Biology. 347: 167-79
Snarr BS, O'Neal JL, Chintalapudi MR, et al. (2007) Isl1 expression at the venous pole identifies a novel role for the second heart field in cardiac development. Circulation Research. 101: 971-4
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