Aditi U. Gurkar, Ph.D.
Affiliations: | 2010 | Boston University, Boston, MA, United States |
Area:
Molecular Biology, Cell BiologyGoogle:
"Aditi Gurkar"Parents
Sign in to add mentor| Cyrus Vaziri | grad student | 2010 | Boston University | |
| (ATM/ATR-mediated phosphorylation of RAD18 is required for efficient S-phase progression and replication fork stability.) | ||||
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Publications
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| Guillermier C, Kumar NV, Bracken RC, et al. (2024) Nanoscale imaging of DNA-RNA identifies transcriptional plasticity at heterochromatin. Life Science Alliance. 7 |
| Han S, Sims A, Aceto A, et al. (2023) A Chemoptogenetic Tool for Spatiotemporal Induction of Oxidative DNA Lesions . Genes. 14 |
| Hamsanathan S, Anthonymuthu T, Han S, et al. (2022) Integrated -omics approach reveals persistent DNA damage rewires lipid metabolism and histone hyperacetylation via MYS-1/Tip60. Science Advances. 8: eabl6083 |
| Marchal L, Hamsanathan S, Karthikappallil R, et al. (2021) Analysis of representative mutants for key DNA repair pathways on healthspan in Caenorhabditis elegans. Mechanisms of Ageing and Development. 111573 |
| Zhao J, Zhang L, Lu A, et al. (2020) ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. Aging. 12 |
| Gurkar AU, Robinson AR, Cui Y, et al. (2018) Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging. Redox Biology. 18: 191-199 |
| Niedernhofer LJ, Gurkar AU, Wang Y, et al. (2018) Nuclear Genomic Instability and Aging. Annual Review of Biochemistry. 87: 295-322 |
| Czerwińska J, Nowak M, Wojtczak P, et al. (2018) ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation. Free Radical Biology & Medicine |
| Robinson AR, Yousefzadeh MJ, Rozgaja TA, et al. (2018) Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biology. 17: 259-273 |
| Zhao J, Fuhrmann-Stroissnigg H, Gurkar AU, et al. (2017) Quantitative Analysis of Cellular Senescence in Culture and In Vivo. Current Protocols in Cytometry. 79: 9.51.1-9.51.25 |