Ali A. Zarrin, Ph.D.
Affiliations: | 2000 | University of Toronto, Toronto, ON, Canada |
Area:
Immunology, Molecular BiologyGoogle:
"Ali Zarrin"Parents
Sign in to add mentorNeil L. Berinstein | grad student | 2000 | University of Toronto | |
(Characterization of the human recombination activating gene 1 (RAG1) and RAG2 promoter regions.) |
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Publications
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Bao K, Zhang J, Scherl A, et al. (2022) Activation-Induced Cytidine Deaminase Impacts the Primary Antibody Repertoire in Naive Mice. Journal of Immunology (Baltimore, Md. : 1950) |
Corzo CA, Varfolomeev E, Setiadi AF, et al. (2020) The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells. Science Signaling. 13 |
Rajapaksa NS, Gobbi A, Drobnick J, et al. (2020) Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity. Acs Medicinal Chemistry Letters. 11: 327-333 |
Easley-Neal C, Foreman O, Sharma N, et al. (2019) CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions. Frontiers in Immunology. 10: 2199 |
Rathore N, Ramani SR, Pantua H, et al. (2018) Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease. Plos Genetics. 14: e1007427 |
Xu D, Matsumoto ML, McKenzie BS, et al. (2017) TPL2 kinase action and control of inflammation. Pharmacological Research |
Senger K, Pham VC, Varfolomeev E, et al. (2017) The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation. Science Signaling. 10 |
Sun Y, Peng I, Webster JD, et al. (2015) Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response. Science Signaling. 8: ra122 |
Senger K, Hackney J, Payandeh J, et al. (2015) Antibody Isotype Switching in Vertebrates. Results and Problems in Cell Differentiation. 57: 295-324 |
Burch JD, Barrett K, Chen Y, et al. (2015) Tetrahydroindazoles as Interleukin-2 Inducible T-Cell Kinase Inhibitors. Part II. Second-Generation Analogues with Enhanced Potency, Selectivity, and Pharmacodynamic Modulation in Vivo. Journal of Medicinal Chemistry. 58: 3806-16 |