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Dean A. Wiseman, Ph.D.

Affiliations: 
2004 Purdue University, West Lafayette, IN, United States 
Area:
Pharmacology, Oncology, Radiology, Molecular Biology
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"Dean Wiseman"
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Pamela L. Crowell grad student 2004 Purdue
 (Mechanism of action of, and combination chemotherapy with isoprenoids perillyl alcohol, farnesol, and geraniol in in vitro and in vivo models of human pancreatic adenocarcinoma.)

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Publications

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Wiseman DA, Thurmond DC. (2012) The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act. Current Diabetes Reviews. 8: 303-15
Wiseman DA, Kalwat MA, Thurmond DC. (2011) Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosis. The Journal of Biological Chemistry. 286: 16344-54
Sud N, Wiseman DA, Black SM. (2010) Caveolin 1 is required for the activation of endothelial nitric oxide synthase in response to 17beta-estradiol. Molecular Endocrinology (Baltimore, Md.). 24: 1637-49
Alieva IB, Zemskov EA, Kireev II, et al. (2010) Microtubules growth rate alteration in human endothelial cells. Journal of Biomedicine & Biotechnology. 2010: 671536
Sharma S, Kumar S, Wiseman DA, et al. (2010) Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow. Vascular Pharmacology. 53: 38-52
Tian J, Hou Y, Lu Q, et al. (2010) A novel role for caveolin-1 in regulating endothelial nitric oxide synthase activation in response to H2O2 and shear stress. Free Radical Biology & Medicine. 49: 159-70
Wiseman DA, Sharma S, Black SM. (2010) Elevated zinc induces endothelial apoptosis via disruption of glutathione metabolism: role of the ADP translocator. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 23: 19-30
Sharma S, Kumar S, Sud N, et al. (2009) Alterations in lung arginine metabolism in lambs with pulmonary hypertension associated with increased pulmonary blood flow. Vascular Pharmacology. 51: 359-64
Kumar S, Sun X, Wiseman DA, et al. (2009) Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activity. Dna and Cell Biology. 28: 119-29
Oishi PE, Wiseman DA, Sharma S, et al. (2008) Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: a role for oxidative stress. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L756-66
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