Jason H. Bielas, Ph.D.

Affiliations: 
2003 York University, Toronto, Ontario, Canada 
Area:
Genetics, Cell Biology
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"Jason Bielas"

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John A. Heddle grad student 2003 York University
 (The role of proliferation in mutagenesis.)
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Publications

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Rose JC, Stephany JJ, Valente WJ, et al. (2017) Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics. Nature Methods
Valente WJ, Ericson NG, Long AS, et al. (2016) Mitochondrial DNA exhibits resistance to induced point and deletion mutations. Nucleic Acids Research
Gregory MT, Bertout JA, Ericson NG, et al. (2015) Targeted single molecule mutation detection with massively parallel sequencing. Nucleic Acids Research
Wanagat J, Ahmadieh N, Bielas JH, et al. (2015) Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice. Experimental Gerontology. 61: 15-9
Ericson NG, Kulawiec M, Vermulst M, et al. (2012) Decreased mitochondrial DNA mutagenesis in human colorectal cancer. Plos Genetics. 8: e1002689
Allen JM, Simcha DM, Ericson NG, et al. (2011) Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication. Nucleic Acids Research. 39: 7020-33
Wright JH, Modjeski KL, Bielas JH, et al. (2011) A random mutation capture assay to detect genomic point mutations in mouse tissue Nucleic Acids Research. 39: e73
Kulawiec M, Salk JJ, Ericson NG, et al. (2010) Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer. Environmental and Molecular Mutagenesis. 51: 427-39
Vermulst M, Bielas JH, Loeb LA. (2008) Quantification of random mutations in the mitochondrial genome Methods. 46: 263-268
Loeb LA, Bielas JH, Beckman RA. (2008) Cancers exhibit a mutator phenotype: Clinical implications Cancer Research. 68: 3551-3557
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