James W. Kaspar, Ph.D.
Affiliations: | 2011 | Toxicology | University of Maryland School of Medicine, Baltimore, MD, United States |
Area:
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"James Kaspar"Parents
Sign in to add mentor| Anil K. Jaiswal | grad student | 2011 | University of Maryland Medical School | |
| (Negative Regulators of Nrf2 in the Early Response to Oxidative Stress.) | ||||
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Publications
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| Kaspar JW, Niture SK, Jaiswal AK. (2017) Retraction: Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression. Journal of Cell Science. 130: 814 |
| Kaspar JW, Niture SK, Jaiswal AK. (2012) Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression. Journal of Cell Science. 125: 1027-38 |
| Kaspar JW, Jaiswal AK. (2011) Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression Faseb Journal. 25: 1076-1087 |
| Kaspar JW, Jaiswal AK. (2010) An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance. The Journal of Biological Chemistry. 285: 21349-58 |
| Kaspar JW, Jaiswal AK. (2010) Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression. The Journal of Biological Chemistry. 285: 153-62 |
| Niture SK, Kaspar JW, Shen J, et al. (2010) Nrf2 signaling and cell survival. Toxicology and Applied Pharmacology. 244: 37-42 |
| Kaspar JW, Niture SK, Jaiswal AK. (2009) Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radical Biology & Medicine. 47: 1304-9 |