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Zucai Suo

Affiliations:

Chemistry and Biochemistry

Ohio State University, Columbus, Columbus, OH

Area:

enzymes involved in DNA/RNA replication, Hepatitis C replication, drug design

Website:

http://chemistry.osu.edu/faculty/suo

Google:

Bio:

http://chemistry.osu.edu/~suo.3
http://chemistry.gsu.edu/faculty/Huang/Zucai_Suo,%202009-5.pdf

Mean distance: 7.34

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Parents

Kenneth A. Johnson	grad student	1997	Penn State
Christopher T. Walsh	post-doc	1998-2000	Harvard Medical School

Children

Walter Zahurancik	grad student	2012-	Ohio State
Kevin A. Fiala	grad student	2007	Ohio State
Jessica A. Brown	grad student	2010	Ohio State
Varun V. Gadkari	grad student	2012-2017	Ohio State

Collaborators

BETA: Related publications

Publications

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Chu WT, Suo Z, Wang J. (2024) Three-metal ion mechanism of cross-linked and uncross-linked DNA polymerase β: A theoretical study. The Journal of Chemical Physics. 160
Zhao W, Hussen AS, Freudenthal BD, et al. (2024) Mitochondrial transcription factor A (TFAM) has 5'-deoxyribose phosphate lyase activity in vitro. Dna Repair. 137: 103666
Kumar A, Reed AJ, Zahurancik WJ, et al. (2022) Interlocking activities of DNA polymerase β in the base excision repair pathway. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118940119
Chu X, Suo Z, Wang J. (2021) Investigating the Conformational Dynamics of a Y-Family DNA Polymerase during Its Folding and Binding to DNA and a Nucleotide. Jacs Au. 2: 341-356
Raper AT, Maxwell BA, Suo Z. (2021) Dynamic processing of a common oxidative DNA lesion by the first two enzymes of the base excision repair pathway. Journal of Molecular Biology. 166811
Zahurancik WJ, Suo Z. (2020) Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenzyme. The Journal of Biological Chemistry. 295: 17251-17264
Chu X, Suo Z, Wang J. (2020) Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase. Elife. 9
Zahurancik WJ, Suo Z. (2020) Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase epsilon holoenzyme. The Journal of Biological Chemistry
Galati MA, Hodel KP, Gams MS, et al. (2020) Cancers from novel Pole mutant mouse models provide insights into polymerase-mediated hypermutagenesis and immune checkpoint blockade. Cancer Research
Hodel KP, Sun MJS, Ungerleider N, et al. (2020) POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status. Molecular Cell

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