Christopher Cummings
Affiliations: | Cancer Biology | University of Colorado Anschutz Medical Campus, Denver, Aurora, CO |
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"Christopher Cummings"
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| Sebti SM, Kazi A, Xiang S, et al. (2019) Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| McDaniel NK, Cummings CT, Iida M, et al. (2018) MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents. Molecular Cancer Therapeutics |
| Cummings CT, Zhang W, Davies KD, et al. (2015) Small molecule inhibition of MERTK is efficacious in non-small cell lung cancer models independent of driver oncogene status. Molecular Cancer Therapeutics |
| Cummings CT, Linger RM, Cohen RA, et al. (2014) Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer. Oncotarget. 5: 10434-45 |
| Morgan MJ, Gamez G, Menke C, et al. (2014) Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent. Autophagy. 10: 1814-26 |
| Zhang W, DeRyckere D, Hunter D, et al. (2014) UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor. Journal of Medicinal Chemistry. 57: 7031-41 |
| DeRyckere DA, Hill AA, Wang X, et al. (2014) Abstract 1740: Development of a novel small molecule MER tyrosine kinase inhibitor with therapeutic activity in cell culture and mouse models of acute lymphoblastic leukemia Cancer Research. 74: 1740-1740 |
| Zhang W, Zhang D, Stashko MA, et al. (2013) Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors. Journal of Medicinal Chemistry. 56: 9683-92 |
| Christoph S, Deryckere D, Schlegel J, et al. (2013) UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Molecular Cancer Therapeutics. 12: 2367-77 |
| Cummings CT, Deryckere D, Earp HS, et al. (2013) Molecular pathways: MERTK signaling in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5275-80 |