Craig M. Crews, Ph.D.
Affiliations: | Molecular, Cellular & Developmental Biology | Yale University, New Haven, CT |
Area:
organic synthesis, pharmacology, molecular biologyWebsite:
http://crewslab.yale.edu/Google:
"Craig M. Crews"Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Raymond L. Erikson | grad student | 1993 | Harvard |
| Stuart L. Schreiber | post-doc | 1993-1995 | Harvard (Chemistry Tree) |
Children
Sign in to add trainee| Lihao Meng | grad student | 2000 | Yale (Chemistry Tree) |
| Jing-Ruey J. Yeh | grad student | 2001 | Yale (Chemistry Tree) |
| Benjamin H. Kwok | grad student | 2002 | Yale (Chemistry Tree) |
| Cathleen M. Brdlik | grad student | 2003 | Yale (Chemistry Tree) |
| John S. Schneekloth | grad student | 2006 | Yale (Chemistry Tree) |
| Ashley R. Schneekloth | grad student | 2009 | Yale (Chemistry Tree) |
| Leah J. Campbell | grad student | 2011 | Yale (Chemistry Tree) |
| Dennis Buckley | grad student | 2013 | Yale (Chemistry Tree) |
| Devin J. Noblin | grad student | 2014 | Yale (Chemistry Tree) |
| Kanak S. Raina | grad student | 2014 | Yale (Chemistry Tree) |
| Arseniy Butrin | post-doc | Yale (Chemistry Tree) | |
| Grant Flowers | post-doc | Yale (Chemistry Tree) | |
| Philipp Ottis | post-doc | Yale (Chemistry Tree) | |
| Momar Toure | post-doc | Yale (Chemistry Tree) | |
| Mackenzie W. Krone | post-doc | 2021- | Yale (Chemistry Tree) |
| Mathieu Pucheault | post-doc | 2005-2006 | Yale (Chemistry Tree) |
| Alessio Ciulli | post-doc | 2009-2009 | Yale (Chemistry Tree) |
| Timothy W Corson | post-doc | 2007-2010 | (Chemistry Tree) |
| Doris Hellerschmied | post-doc | 2015-2019 | Yale (Chemistry Tree) |
| Jacques Saarbach | post-doc | 2020-2023 | Yale (Chemistry Tree) |
BETA: Related publications
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Publications
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| Li K, Krone MW, Butrin A, et al. (2024) Development of Ligands and Degraders Targeting MAGE-A3. Journal of the American Chemical Society |
| Raina K, Forbes CD, Stronk R, et al. (2024) Regulated induced proximity targeting chimeras-RIPTACs-A heterobifunctional small molecule strategy for cancer selective therapies. Cell Chemical Biology |
| Hu Z, Chen PH, Li W, et al. (2024) EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling. Science Advances. 10: eadj7251 |
| Chirnomas D, Hornberger KR, Crews CM. (2023) Protein degraders enter the clinic - a new approach to cancer therapy. Nature Reviews. Clinical Oncology |
| Raina K, Forbes CD, Stronk R, et al. (2023) Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively. Biorxiv : the Preprint Server For Biology |
| Swartzel JC, Bond MJ, Pintado-Urbanc AP, et al. (2022) Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC. Acs Chemical Biology |
| Li K, Crews CM. (2022) PROTACs: past, present and future. Chemical Society Reviews |
| Nalawansha DA, Li K, Hines J, et al. (2022) Hijacking Methyl Reader Proteins for Nuclear-Specific Protein Degradation. Journal of the American Chemical Society. 144: 5594-5605 |
| Békés M, Langley DR, Crews CM. (2022) PROTAC targeted protein degraders: the past is prologue. Nature Reviews. Drug Discovery |
| Chen PH, Hu Z, An E, et al. (2021) Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs). Acs Chemical Biology |