Florian Hollfelder
Affiliations: | University of Cambridge, Cambridge, England, United Kingdom |
Area:
enzyme mechanism, directed evololution, physical-organic chemistry, microfluidicsGoogle:
"Florian Hollfelder"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Daniel Herschlag | research assistant | 1994-1994 | Stanford Medical School |
| Anthony J. Kirby | grad student | 1994-1998 | |
| Christopher T. Walsh | post-doc | 1998-2001 | Harvard Medical School |
Children
Sign in to add trainee| Stefanie Jonas | grad student | 2006-2009 | ETH Zürich |
| Viktor Stein | grad student | 2007-2011 | Technical University of Darmstadt |
| Yolanda Schaerli | grad student | 2008-2011 | EPFL |
| Alexander Andre Cobb | post-doc | ||
| Josiel Barbosa Domingos | post-doc | 2003-2005 | |
| Bert van Loo | post-doc | 2006-2011 | Northumbria University |
| Balint Kintses | post-doc | 2009-2012 | Cambridge (Cell Biology Tree) |
Collaborators
Sign in to add collaborator| Kevin Dalby | collaborator | 1992- | |
| Marko Hyvonen | collaborator | 2005- | Cambridge (Computational Biology Tree) |
BETA: Related publications
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Publications
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| Fischer K, Lulla A, So TY, et al. (2024) Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells. Nature Biotechnology |
| Ladeveze S, Zurek PJ, Kaminski TS, et al. (2023) Versatile Product Detection via Coupled Assays for Ultrahigh-Throughput Screening of Carbohydrate-Active Enzymes in Microfluidic Droplets. Acs Catalysis. 13: 10232-10243 |
| Yam-Puc JC, Hosseini Z, Horner EC, et al. (2023) Age-associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade. Nature Communications. 14: 3292 |
| Knyphausen P, Rangel Pereira M, Brear P, et al. (2023) Evolution of protease activation and specificity via alpha-2-macroglobulin-mediated covalent capture. Nature Communications. 14: 768 |
| Neun S, Brear P, Campbell E, et al. (2022) Functional metagenomic screening identifies an unexpected β-glucuronidase. Nature Chemical Biology |
| Scheele RA, Lindenburg LH, Petek M, et al. (2022) Droplet-based screening of phosphate transfer catalysis reveals how epistasis shapes MAP kinase interactions with substrates. Nature Communications. 13: 844 |
| Lindenburg LH, Pantelejevs T, Gielen F, et al. (2021) Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Holstein JM, Gylstorff C, Hollfelder F. (2021) Cell-free Directed Evolution of a Protease in Microdroplets at Ultrahigh Throughput. Acs Synthetic Biology |
| Lindenburg L, Hollfelder F. (2021) 'NAD-display': Ultrahigh-Throughput in Vitro Screening of NAD(H) Dehydrogenases Using Bead Display and Flow Cytometry. Angewandte Chemie (International Ed. in English) |
| Zurek PJ, Hours R, Schell U, et al. (2020) Growth amplification in ultrahigh-throughput microdroplet screening increases sensitivity of clonal enzyme assays and minimizes phenotypic variation. Lab On a Chip |