Evan Lien, PhD

Affiliations: 
Pathology Harvard Medical School - Beth Israel Deaconess Medical Center 
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"Evan Lien"
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Publications

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Lee BS, Park YI, Liu H, et al. (2025) The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma. Cancer Letters. 217842
Navarro-Traxler AJ, Ghisolfi L, Lien EC, et al. (2025) The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glycosylation. Biorxiv : the Preprint Server For Biology
Jonker PB, Sadullozoda M, Cognet G, et al. (2025) Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis. Biorxiv : the Preprint Server For Biology
House RRJ, Tovar EA, Essenburg CJ, et al. (2024) NF1 deficiency drives metabolic reprogramming in ER+ breast cancer. Molecular Metabolism. 101876
Jeong YJ, Rogers TJ, Anderson CE, et al. (2023) Tumor lipid metabolism: a mechanistic link between diet and cancer progression. Current Opinion in Biotechnology. 84: 102993
Tsang T, He Q, Cohen EB, et al. (2022) Upregulation of Receptor Tyrosine Kinase Activity and Stemness as Resistance Mechanisms to Akt Inhibitors in Breast Cancer. Cancers. 14
Dibble CC, Barritt SA, Perry GE, et al. (2022) PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature
Li Z, Ji BW, Dixit PD, et al. (2022) Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nature Metabolism
Gouirand V, Gicquel T, Lien EC, et al. (2022) Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. The Embo Journal. e110466
Lau AN, Li Z, Danai LV, et al. (2020) Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. 9
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