Evan Lien, PhD
Affiliations: | Pathology | Harvard Medical School - Beth Israel Deaconess Medical Center |
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"Evan Lien"
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Publications
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| House RRJ, Tovar EA, Essenburg CJ, et al. (2024) NF1 deficiency drives metabolic reprogramming in ER+ breast cancer. Molecular Metabolism. 101876 |
| Jeong YJ, Rogers TJ, Anderson CE, et al. (2023) Tumor lipid metabolism: a mechanistic link between diet and cancer progression. Current Opinion in Biotechnology. 84: 102993 |
| Tsang T, He Q, Cohen EB, et al. (2022) Upregulation of Receptor Tyrosine Kinase Activity and Stemness as Resistance Mechanisms to Akt Inhibitors in Breast Cancer. Cancers. 14 |
| Dibble CC, Barritt SA, Perry GE, et al. (2022) PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature |
| Li Z, Ji BW, Dixit PD, et al. (2022) Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nature Metabolism |
| Gouirand V, Gicquel T, Lien EC, et al. (2022) Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. The Embo Journal. e110466 |
| Lau AN, Li Z, Danai LV, et al. (2020) Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. 9 |
| Lien EC, Vander Heiden MG. (2019) A framework for examining how diet impacts tumour metabolism. Nature Reviews. Cancer |
| Lien EC, Ghisolfi L, Geck RC, et al. (2017) Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT. Science Signaling. 10 |
| Lien EC, Dibble CC, Toker A. (2017) PI3K signaling in cancer: beyond AKT. Current Opinion in Cell Biology. 45: 62-71 |