Jonathan Wilson Yewdell

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I began my research career as an undergraduate in Arnold Levine’s laboratory (Princeton University) where for my senior thesis I studied immune rejection of adenovirus transformed cells, graduating with a degree in Biochemistry in 1975. Though our approach was hopelessly naïve, I developed an interest in immune recognition of viruses that would become the major topic of my future research career. I obtained my Ph.D. in 1981 from the University of Pennsylvania (with an MD, with the tacit agreement that I would never practice medicine!), working with Walter Gerhard (Wistar Institute), the first to generate anti-viral monoclonal antibodies. For my thesis, I used monoclonal antibodies to better understand immune recognition of influenza and other viruses and immune driven viral evolution.
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