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Sign in to add mentor| Alexandra C. Newton | grad student | 2005-2011 | UCSD (Chemistry Tree) | |
| (Regulation of PHLPP and Akt signaling.) | ||||
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Publications
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| Torres-Ayuso P, Katerji M, Mehlich D, et al. (2023) PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer. Cell Chemical Biology |
| Jensen CC, Clements AN, Liou H, et al. (2023) PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion. The Journal of Cell Biology. 222 |
| Clements AN, Warfel NA. (2022) Targeting PIM Kinases to Improve the Efficacy of Immunotherapy. Cells. 11 |
| Toth RK, Solomon R, Warfel NA. (2022) Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28. Cells. 11 |
| Warfel NA. (2022) Defining the mechanisms underlying cyclin dependent kinase control of HIF-1α. Oncotarget. 13: 454-455 |
| Casillas AL, Chauhan SS, Toth RK, et al. (2021) Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors. Oncogene |
| Toth RK, Warfel NA. (2020) Targeting PIM Kinases to Overcome Therapeutic Resistance in Cancer. Molecular Cancer Therapeutics |
| Toth RK, Tran JD, Muldong MT, et al. (2019) Hypoxia-induced PIM kinase and laminin-activated integrin α6 mediate resistance to PI3K inhibitors in bone-metastatic CRPC. American Journal of Clinical and Experimental Urology. 7: 297-312 |
| Chauhan SS, Warfel NA. (2018) Targeting PIM kinases to oppose hypoxia-mediated therapeutic resistance. Oncoscience. 5: 254-255 |
| Song JH, Singh N, Luevano LA, et al. (2018) Mechanisms behind resistance to PI3K Inhibitor treatment induced by the PIM kinase. Molecular Cancer Therapeutics |