Maggie So, Ph.D.

Immunobiology University of Arizona, Tucson, AZ 
bacterial genetics, bacterial pathogenesis
"Maggie So"

Maggie So began her independent research career at Cold Spring Harbor Labs, then the Scripps Research Institute. During this period she developed her program on the molecular mechanisms of antigenic variation in the pathogenic Neisseria. In 1993, she became chair of the Molecular Microbiology Department at Oregon Health Sciences University, where she gathered a group of highly collaborative scientists interested in the various facets of microbial pathogenesis. It was here that she developed her program on the cell biology of Neisseria pathogenesis, and on the role played by the Type IV pilus in host cell signaling. In 2007, she joined the BIO5 Institute and the Department of Immunobiology at University of Arizona, where she spearheads the Microbial Pathogenesis program and continues her research on the Type IV pilus, and where she began a program on commensal Neisseria.

Cross-listing: ID Tree


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Stanley Falkow grad student UW Medical School (ID Tree)
Brian J. McCarthy grad student UCSF (Anatomy Tree)
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Cabello FC, Cohen SN, Curtiss R, et al. (2018) Farewell Stan Stanley Falkow: 1934-2018. Environmental Microbiology
Biais N, Higashi DL, Brujic J, et al. (2010) Force-dependent polymorphism in type IV pili reveals hidden epitopes. Proceedings of the National Academy of Sciences of the United States of America. 107: 11358-63
Biais N, Ladoux B, Higashi D, et al. (2008) Cooperative retraction of bundled type IV pili enables nanonewton force generation Plos Biology. 6: 907-913
Higashi DL, Lee SW, Snyder A, et al. (2007) Dynamics of Neisseria gonorrhoeae attachment: microcolony development, cortical plaque formation, and cytoprotection. Infection and Immunity. 75: 4743-53
Friedrich A, Arvidson CG, Shafer WM, et al. (2007) Two ABC transporter operons and the antimicrobial resistance gene mtrF are pilT responsive in Neisseria gonorrhoeae. Journal of Bacteriology. 189: 5399-402
Weyand NJ, Lee SW, Higashi DL, et al. (2006) Monoclonal antibody detection of CD46 clustering beneath Neisseria gonorrhoeae microcolonies. Infection and Immunity. 74: 2428-35
Lee SW, Higashi DL, Snyder A, et al. (2005) PilT is required for PI(3,4,5)P3-mediated crosstalk between Neisseria gonorrhoeae and epithelial cells. Cellular Microbiology. 7: 1271-84
Larson JA, Higashi DL, Stojiljkovic I, et al. (2002) Replication of Neisseria meningitidis within epithelial cells requires TonB-dependent acquisition of host cell iron. Infection and Immunity. 70: 1461-7
Merz AJ, So M. (2000) Interactions of pathogenic neisseriae with epithelial cell membranes. Annual Review of Cell and Developmental Biology. 16: 423-57
Merz AJ, So M, Sheetz MP. (2000) Pilus retraction powers bacterial twitching motility. Nature. 407: 98-102
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