Jorge L Ruas, Pharm.D., Ph.D.

Affiliations:

2023-

Pharmacology

The University of Michigan Medical School

Area:

Physiology, Skeletal Muscle, Metabolism, inter-organ crosstalk.

Website:

www.ruaslab.science

Google:

"Jorge Ruas"

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Parents

Teresa Pereira	grad student	1999-2005	Karolinska
Lorenz Poellinger	grad student	1999-2005	Karolinska
Lorenz Poellinger	post-doc	2005-2006	Karolinska
Bruce Spiegelman	post-doc	2006-2011	Harvard Medical School

Children

Margareta Porsmyr-Palmertz	research assistant	2015-	Karolinska
Emma Stoner	research assistant	2024-	The University of Michigan Medical School
Dawn Wilbert	research assistant	2024-	The University of Michigan Medical School
Kyle D. Dumont	grad student	2021-	Karolinska
Leandro Z Agudelo	grad student	2017	Karolinska
Manizheh Izadi	grad student	2018	Karolinska
Paula Valente-Silva	grad student	2021	Karolinska
Shamim Dadvar	grad student	2018-2021	Karolinska
Stine Marie Præstholm	post-doc	2021-	Karolinska
Gerard Baines-Gaya	post-doc	2023-	Karolinska
Aurel Leuchtmann	post-doc	2024-	The University of Michigan Medical School
Melissa Quinn	post-doc	2024-	The University of Michigan Medical School
Amanda Pettersson-Klein	post-doc	2011-2017	Karolinska
Vicente Martinez-Redondo	post-doc	2012-2017	Karolinska
Duarte Ferreira	post-doc	2013-2018	Karolinska
Lars Ketscher	post-doc	2016-2018	Karolinska
Kyle Martin	post-doc	2017-2020	Karolinska
Jorge C. Correia	post-doc	2014-2022	Karolinska
Michele Azzolini	post-doc	2017-2022	Karolinska
Igor Cervenka	post-doc	2015-2023	Karolinska
Serge Ducommun	post-doc	2017-2023	Karolinska
Paulo Jannig	post-doc	2017-2023	Karolinska

Collaborators

BETA: Related publications

Publications

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Dumont KD, Jannig PR, Porsmyr-Palmertz M, et al. (2025) Constitutive loss of kynurenine-3-monooxygenase changes circulating kynurenine metabolites without affecting systemic energy metabolism. American Journal of Physiology. Endocrinology and Metabolism. 328: E274-E285
Pham TCP, Raun SH, Havula E, et al. (2024) The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms. Nature Communications. 15: 9826
Wadsworth BJ, Leiwe M, Minogue EA, et al. (2024) A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue. Elife. 12
Correia JC, Jannig PR, Gosztyla ML, et al. (2024) Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling. Proceedings of the National Academy of Sciences of the United States of America. 121: e2319724121
Dedic B, Westerberg L, Mosqueda Solís A, et al. (2024) Senescence detection using reflected light. Aging Cell. e14295
Ducommun S, Jannig PR, Cervenka I, et al. (2024) Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. Molecular Metabolism. 101912
Caria I, Nunes MJ, Ciraci V, et al. (2023) NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 166980
Spratt J, Dias JM, Kolonelou C, et al. (2023) Multivalent insulin receptor activation using insulin-DNA origami nanostructures. Nature Nanotechnology
Correia JC, Jannig PR, Gosztyla ML, et al. (2023) Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration. Biorxiv : the Preprint Server For Biology
Luo Q, Pui HP, Chen J, et al. (2023) Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence. Cell Reports. 42: 112021