Collin Challis, Ph.D.

Affiliations: 
2006-2008 Molecular and Cellular Neuroscience Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2008-2009 Psychological and Brain Sciences Indiana University, Bloomington, Bloomington, IN, United States 
 2009-2015 Psychiatry University of Pennsylvania, Philadelphia, PA, United States 
 2015- Biology and Bioengineering California Institute of Technology, Pasadena, CA 
Area:
Neural circuits, neurodegeneration
Website:
http://glab.caltech.edu
Google:
"Collin Challis"
Mean distance: 14.67 (cluster 6)
 
SNBCP

Parents

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Olivier BERTON grad student 2009-2014 Penn
 (Top-down control of serotonergic systems in socioaffective choices and depression-like behaviors.)
Viviana Gradinaru post-doc 2015- Caltech
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Publications

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Griffiths JA, Yoo BB, Thuy-Boun P, et al. (2024) Peripheral neuronal activation shapes the microbiome and alters gut physiology. Cell Reports. 43: 113953
Rauch JN, Luna G, Guzman E, et al. (2020) LRP1 is a master regulator of tau uptake and spread. Nature. 580: 381-385
Challis C, Hori A, Sampson TR, et al. (2020) Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice. Nature Neuroscience
Sampson TR, Challis C, Jain N, et al. (2020) A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice. Elife. 9
Sampson TR, Challis C, Jain N, et al. (2020) Author response: A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice Elife
Challis RC, Kumar SR, Chan KY, et al. (2019) Publisher Correction: Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols
Challis RC, Ravindra Kumar S, Chan KY, et al. (2019) Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols
Greenbaum A, Jang MJ, Challis C, et al. (2017) Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? Bmc Biology. 15: 87
Sampson TR, Debelius JW, Thron T, et al. (2016) Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease. Cell. 167: 1469-1480.e12
Challis C, Berton O. (2015) Top-Down Control of Serotonin Systems by the Prefrontal Cortex: A Path toward Restored Socioemotional Function in Depression. Acs Chemical Neuroscience. 6: 1040-54
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