Brian A. Joughin

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
computational biology, cancer biology, systems biology
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"Brian Joughin"
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Parents

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Bruce Tidor grad student 2001-2006 MIT
Michael B. Yaffe grad student 2001-2006 MIT
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Publications

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van de Kooij B, van der Wal FJ, Rother MB, et al. (2023) The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks. Biorxiv : the Preprint Server For Biology
Green BL, Gamble LA, Diggs LP, et al. (2023) Early immune changes support signet ring cell dormancy in CDH1-driven hereditary diffuse gastric carcinogenesis. Molecular Cancer Research : McR
Netterfield TS, Ostheimer GJ, Tentner AR, et al. (2023) Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition. Cell Systems. 14: 582-604.e10
Goretti Riça I, Joughin BA, Teke ME, et al. (2022) Neutrophil heterogeneity and emergence of a distinct population of CD11b/CD18-activated low-density neutrophils after trauma. The Journal of Trauma and Acute Care Surgery. 94: 187-196
Moore HB, Neal MD, Bertolet M, et al. (2022) Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion. Annals of Surgery Open : Perspectives of Surgical History, Education, and Clinical Approaches. 3
Sriram G, Milling LE, Chen JK, et al. (2021) The injury response to DNA damage in live tumor cells promotes antitumor immunity. Science Signaling. 14: eabc4764
Cahill LA, Joughin BA, Kwon WY, et al. (2020) Multiplexed Plasma Immune Mediator Signatures Can Differentiate Sepsis From NonInfective SIRS: American Surgical Association 2020 Annual Meeting Paper. Annals of Surgery. 272: 604-610
Krismer K, Bird MA, Varmeh S, et al. (2020) Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression. Cell Reports. 32: 108064
Stopfer LE, Mesfin JM, Joughin BA, et al. (2020) Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition. Nature Communications. 11: 2760
Strasser SD, Ghazi PC, Starchenko A, et al. (2019) Substrate-based kinase activity inference identifies MK2 as driver of colitis. Integrative Biology : Quantitative Biosciences From Nano to Macro
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