John V. Moran
Affiliations: | Human Genetics | University of Michigan Medical School Ann Arbor |
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"John Moran"Parents
Sign in to add mentorPhilip S. Perlman | grad student | UT Southwestern | |
Haig H. Kazazian | post-doc | Johns Hopkins |
Children
Sign in to add traineeChristine R. Beck | grad student | 2005-2011 | University of Michigan Medical School Ann Arbor |
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Publications
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Ward JR, Khan A, Torres S, et al. (2022) Condensin I and condensin II proteins form a LINE-1 dependent super condensin complex and cooperate to repress LINE-1. Nucleic Acids Research |
Halo JV, Pendleton AL, Shen F, et al. (2021) Long-read assembly of a Great Dane genome highlights the contribution of GC-rich sequence and mobile elements to canine genomes. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Zhu X, Zhou B, Pattni R, et al. (2021) Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia. Nature Neuroscience |
Zhou W, Emery SB, Flasch DA, et al. (2019) Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. Nucleic Acids Research |
Moldovan JB, Wang Y, Shuman S, et al. (2019) RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA. Proceedings of the National Academy of Sciences of the United States of America |
Miyoshi T, Makino T, Moran JV. (2019) Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition. Molecular Cell |
Flasch DA, Macia Á, Sánchez L, et al. (2019) Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication. Cell |
Larson PA, Moldovan JB, Jasti N, et al. (2018) Spliced integrated retrotransposed element (SpIRE) formation in the human genome. Plos Biology. 16: e2003067 |
Ward JR, Vasu K, Deutschman E, et al. (2017) Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. Plos Genetics. 13: e1007051 |
Kazazian HH, Moran JV. (2017) Mobile DNA in Health and Disease. The New England Journal of Medicine. 377: 361-370 |