Pawel Swietach

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Physiology; Cardiac science; Cancer biology; pH regulation
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"Pawel Swietach"

Parents

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Richard Vaughan-Jones grad student Oxford (Physiology Academic Tree)
Adrian L Harris research scientist Oxford (Chemistry Tree)
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Publications

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Garbutt P, Cyranka M, Michl J, et al. (2024) The release of GLP-1 from gut L cells is inhibited by low extracellular pH. Obesity (Silver Spring, Md.). 32: 1819-1824
Michl J, Monterisi S, White B, et al. (2023) Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2. Cell Reports. 42: 112601
Russell S, Xu L, Kam Y, et al. (2022) Proton export upregulates aerobic glycolysis. Bmc Biology. 20: 163
Hulikova A, Park KC, Loonat AA, et al. (2022) Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart. Basic Research in Cardiology. 117: 17
Wilson AD, Richards MA, Curtis MK, et al. (2021) Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH. Cardiovascular Research
Kandilci HB, Richards MA, Fournier M, et al. (2020) Cardiomyocyte Na/H Exchanger-1 Activity Is Reduced in Hypoxia. Frontiers in Cardiovascular Medicine. 7: 617038
Swietach P. (2020) What is pH regulation, and why do cancer cells need it? Cancer Metastasis Reviews. 38: 5-15
Richards MA, Simon JN, Ma R, et al. (2019) Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1. Cardiovascular Research
Michl J, Park KC, Swietach P. (2019) Evidence-based guidelines for controlling pH in mammalian live-cell culture systems. Communications Biology. 2: 144
Lee SH, McIntyre D, Honess D, et al. (2018) Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo. British Journal of Cancer
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