beatriz fontoura, ph.d. - Publications

cell biology University of Texas Southwestern Medical Center, Dallas, TX, United States 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Xie Y, Gao S, Zhang K, Bhat P, Clarke BP, Batten K, Mei M, Gazzara M, Shay JW, Lynch KW, Angelos AE, Hill PS, Ivey AL, Fontoura B, Ren Y. Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly. Cell Reports. 42: 112988. PMID 37578863 DOI: 10.1016/j.celrep.2023.112988  0.334
2023 Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Haddad C, Gao S, Esparza M, Cagatay T, Batten K, El Zahed SS, Arnaoutov A, Zhong H, Shay JW, Tolbert BS, ... ... Fontoura BMA, et al. Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex. Nature Communications. 14: 2304. PMID 37085480 DOI: 10.1038/s41467-023-37911-0  0.378
2022 Kehrer T, Cupic A, Ye C, Yildiz S, Bouhhadou M, Crossland NA, Barrall E, Cohen P, Tseng A, Çağatay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena N, ... ... Fontoura BMA, et al. Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 36299428 DOI: 10.1101/2022.10.18.512708  0.306
2022 Esparza M, Bhat P, Fontoura BM. Viral-host interactions during splicing and nuclear export of influenza virus mRNAs. Current Opinion in Virology. 55: 101254. PMID 35908311 DOI: 10.1016/j.coviro.2022.101254  0.363
2022 Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, Ferretti MB, Begg BE, Cagatay T, Shay JW, García-Sastre A, Goldsmith EJ, Chen ZJ, Dasso M, Lynch KW, ... ... Fontoura BMA, et al. Nuclear speckle integrity and function require TAO2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206046119. PMID 35704758 DOI: 10.1073/pnas.2206046119  0.428
2021 Zhang K, Miorin L, Makio T, Dehghan I, Gao S, Xie Y, Zhong H, Esparza M, Kehrer T, Kumar A, Hobman TC, Ptak C, Gao B, Minna JD, Chen Z, ... ... Fontoura BMA, et al. Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression. Science Advances. 7. PMID 33547084 DOI: 10.1126/sciadv.abe7386  0.347
2020 Miorin L, Kehrer T, Sanchez-Aparicio MT, Zhang K, Cohen P, Patel RS, Cupic A, Makio T, Mei M, Moreno E, Danziger O, White KM, Rathnasinghe R, Uccellini M, Gao S, ... ... Fontoura BMA, et al. SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 33097660 DOI: 10.1073/pnas.2016650117  0.307
2020 Aksenova V, Smith A, Lee H, Bhat P, Esnault C, Chen S, Iben J, Kaufhold R, Yau KC, Echeverria C, Fontoura B, Arnaoutov A, Dasso M. Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway. Nature Communications. 11: 4577. PMID 32917881 DOI: 10.1038/S41467-020-18266-2  0.429
2020 Esparza M, Mor A, Niederstrasser H, White K, White A, Zhang K, Gao S, Wang J, Liang J, Sho S, Sakthivel R, Sathe AA, Xing C, Muñoz-Moreno R, Shay JW, ... ... Fontoura BMA, et al. Chemical intervention of influenza virus mRNA nuclear export. Plos Pathogens. 16: e1008407. PMID 32240278 DOI: 10.1371/Journal.Ppat.1008407  0.351
2020 Ren Y, Zhang K, Xie Y, Morris A, Wang Z, Muñoz-Moreno R, Wang J, Zhang L, Esparza M, García-Sastre A, Schey K, Fontoura B. Molecular basis for the exploitation of nuclear mRNA export by influenza A virus The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03380  0.416
2019 Zhang K, Xie Y, Muñoz-Moreno R, Wang J, Zhang L, Esparza M, García-Sastre A, Fontoura BMA, Ren Y. Structural basis for influenza virus NS1 protein block of mRNA nuclear export. Nature Microbiology. PMID 31263181 DOI: 10.1038/S41564-019-0482-X  0.484
2018 Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA. Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30538201 DOI: 10.1073/pnas.1818012115  0.625
2018 Zhang L, Wang J, Muñoz-Moreno R, Kim M, Sakthivel R, Mo W, Shao D, Anantharaman A, García-Sastre A, Conrad NK, Fontoura BMA. Influenza Virus NS1 Protein RNA-Interactome Reveals Intron Targeting. Journal of Virology. PMID 30258002 DOI: 10.1128/Jvi.01634-18  0.441
2018 Chook YM, Fontoura BMA, Rout MP. Günter Blobel 1936-2018. Nature Structural & Molecular Biology. PMID 29610492 DOI: 10.1038/S41594-018-0053-5  0.591
2016 Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Influenza virus mRNA trafficking through host nuclear speckles. Nature Microbiology. 1: 16069. PMID 27572970 DOI: 10.1038/Nmicrobiol.2016.69  0.377
2016 Mor A, White A, Zhang K, Thompson M, Esparza M, Muñoz-Moreno R, Koide K, Lynch KW, García-Sastre A, Fontoura BM. Influenza Virus mRNA Trafficking Through Host Nuclear Speckles. Nature Microbiology. 2016. PMID 27347430 DOI: 10.1038/nmicrobiol.2016.69  0.377
2014 Mor A, White MA, Fontoura BM. Nuclear trafficking in health and disease. Current Opinion in Cell Biology. 28: 28-35. PMID 24530809 DOI: 10.1016/  0.303
2014 Yarbrough ML, Mata MA, Sakthivel R, Fontoura BM. Viral subversion of nucleocytoplasmic trafficking. Traffic (Copenhagen, Denmark). 15: 127-40. PMID 24289861 DOI: 10.1111/tra.12137  0.313
2013 Kuss SK, Mata MA, Zhang L, Fontoura BM. Nuclear imprisonment: viral strategies to arrest host mRNA nuclear export. Viruses. 5: 1824-49. PMID 23872491 DOI: 10.3390/V5071824  0.397
2013 Tsai PL, Chiou NT, Kuss S, García-Sastre A, Lynch KW, Fontoura BM. Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing. Plos Pathogens. 9: e1003460. PMID 23825951 DOI: 10.1371/Journal.Ppat.1003460  0.326
2012 Zhang L, Das P, Schmolke M, Manicassamy B, Wang Y, Deng X, Cai L, Tu BP, Forst CV, Roth MG, Levy DE, García-Sastre A, de Brabander J, Phillips MA, Fontoura BM. Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export. The Journal of Cell Biology. 196: 315-26. PMID 22312003 DOI: 10.1083/Jcb.201107058  0.42
2011 Zhang ZC, Satterly N, Fontoura BM, Chook YM. Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1. Molecular Biology of the Cell. 22: 4657-68. PMID 21965294 DOI: 10.1091/mbc.E11-03-0222  0.638
2008 Pfeifer I, Elsby R, Fernandez M, Faria PA, Nussenzveig DR, Lossos IS, Fontoura BM, Martin WD, Barber GN. NFAR-1 and -2 modulate translation and are required for efficient host defense. Proceedings of the National Academy of Sciences of the United States of America. 105: 4173-8. PMID 18337511 DOI: 10.1073/Pnas.0711222105  0.389
2007 Cansizoglu AE, Lee BJ, Zhang ZC, Fontoura BM, Chook YM. Structure-based design of a pathway-specific nuclear import inhibitor. Nature Structural & Molecular Biology. 14: 452-4. PMID 17435768 DOI: 10.1038/nsmb1229  0.575
2007 Satterly N, Tsai PL, van Deursen J, Nussenzveig DR, Wang Y, Faria PA, Levay A, Levy DE, Fontoura BM. Influenza virus targets the mRNA export machinery and the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 1853-8. PMID 17267598 DOI: 10.1073/pnas.0610977104  0.325
2006 Chakraborty P, Satterly N, Fontoura BM. Nuclear export assays for poly(A) RNAs. Methods (San Diego, Calif.). 39: 363-9. PMID 16935004 DOI: 10.1016/J.Ymeth.2006.07.002  0.354
2006 Faria AM, Levay A, Wang Y, Kamphorst AO, Rosa ML, Nussenzveig DR, Balkan W, Chook YM, Levy DE, Fontoura BM. The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions. Immunity. 24: 295-304. PMID 16546098 DOI: 10.1016/j.immuni.2006.01.014  0.556
2005 Fontoura BM, Faria PA, Nussenzveig DR. Viral interactions with the nuclear transport machinery: discovering and disrupting pathways. Iubmb Life. 57: 65-72. PMID 16036565 DOI: 10.1080/15216540500078608  0.378
2005 Faria PA, Chakraborty P, Levay A, Barber GN, Ezelle HJ, Enninga J, Arana C, van Deursen J, Fontoura BM. VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway. Molecular Cell. 17: 93-102. PMID 15629720 DOI: 10.1016/J.Molcel.2004.11.023  0.396
2003 Enninga J, Levay A, Fontoura BM. Sec13 shuttles between the nucleus and the cytoplasm and stably interacts with Nup96 at the nuclear pore complex. Molecular and Cellular Biology. 23: 7271-84. PMID 14517296 DOI: 10.1128/MCB.23.20.7271-7284.2003  0.333
2002 Enninga J, Levy DE, Blobel G, Fontoura BM. Role of nucleoporin induction in releasing an mRNA nuclear export block. Science (New York, N.Y.). 295: 1523-5. PMID 11809937 DOI: 10.1126/science.1067861  0.562
2001 Fontoura BM, Dales S, Blobel G, Zhong H. The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR. Proceedings of the National Academy of Sciences of the United States of America. 98: 3208-13. PMID 11248057 DOI: 10.1073/Pnas.061014698  0.471
2000 Fontoura BM, Blobel G, Yaseen NR. The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import. The Journal of Biological Chemistry. 275: 31289-96. PMID 10875935 DOI: 10.1074/jbc.M004651200  0.467
1999 Fontoura BM, Blobel G, Matunis MJ. A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96. The Journal of Cell Biology. 144: 1097-112. PMID 10087256 DOI: 10.1083/jcb.144.6.1097  0.649
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