Year |
Citation |
Score |
2024 |
Zhen J, Chen J, Huang H, Liao S, Liu S, Yuan Y, Sun R, Longnecker R, Wu T-T, Zhou ZH. Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features. Journal of Virology. e0119424. PMID 39470208 DOI: 10.1128/jvi.01194-24 |
0.317 |
|
2024 |
Chan YH, Liu Z, Bastard P, Khobrekar N, Hutchison KM, Yamazaki Y, Fan Q, Matuozzo D, Harschnitz O, Kerrouche N, Nakajima K, Amin P, Yatim A, Rinchai D, Chen J, ... ... Longnecker R, et al. Human TMEFF1 is a restriction factor for herpes simplex virus in the brain. Nature. PMID 39048830 DOI: 10.1038/s41586-024-07745-x |
0.377 |
|
2024 |
Zhen J, Chen J, Huang H, Liao S, Liu S, Yuan Y, Sun R, Longnecker R, Wu TT, Zhou ZH. Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features. Biorxiv : the Preprint Server For Biology. PMID 39026862 DOI: 10.1101/2024.07.09.602672 |
0.331 |
|
2024 |
Quan J, Fan Q, Simons LM, Smukowski SN, Pegg C, Longnecker R, Savas JN, Hultquist JF, Smith GA. Leveraging biotin-based proximity labeling to identify cellular factors governing early alphaherpesvirus infection. Mbio. e0144524. PMID 38953638 DOI: 10.1128/mbio.01445-24 |
0.353 |
|
2023 |
Fan Q, Hippler DP, Yang Y, Longnecker R, Connolly SA. Multiple Sites on Glycoprotein H (gH) Functionally Interact with the gB Fusion Protein to Promote Fusion during Herpes Simplex Virus (HSV) Entry. Mbio. e0336822. PMID 36629412 DOI: 10.1128/mbio.03368-22 |
0.405 |
|
2022 |
Ikeda M, Hayes CK, Schaller SJ, Longnecker R. Latent Membrane Proteins from EBV Differentially Target Cellular Pathways to Accelerate MYC-induced Lymphomagenesis. Blood Advances. PMID 35605249 DOI: 10.1182/bloodadvances.2022007695 |
0.396 |
|
2021 |
Fan Q, Longnecker R, Connolly SA. Herpes simplex virus glycoprotein B (gB) mutations define structural sites in domain I, the membrane proximal region, and the cytodomain that regulate entry. Journal of Virology. JVI0105021. PMID 34431697 DOI: 10.1128/JVI.01050-21 |
0.429 |
|
2020 |
Connolly SA, Jardetzky TS, Longnecker R. The structural basis of herpesvirus entry. Nature Reviews. Microbiology. PMID 33087881 DOI: 10.1038/s41579-020-00448-w |
0.39 |
|
2020 |
Fish K, Comoglio F, Shaffer AL, Ji Y, Pan KT, Scheich S, Oellerich A, Doebele C, Ikeda M, Schaller SJ, Nguyen H, Muppidi J, Wright GW, Urlaub H, Serve H, ... ... Longnecker R, et al. Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A. Proceedings of the National Academy of Sciences of the United States of America. PMID 33020271 DOI: 10.1073/pnas.2007946117 |
0.698 |
|
2020 |
Chen J, Schaller S, Jardetzky TS, Longnecker R. EBV gH/gL and KSHV gH/gL bind to different sites on EphA2 to trigger fusion. Journal of Virology. PMID 32847853 DOI: 10.1128/Jvi.01454-20 |
0.485 |
|
2020 |
Giraldo D, Wilcox DR, Longnecker R. The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival. Mbio. 11. PMID 32457247 DOI: 10.1128/Mbio.00921-20 |
0.348 |
|
2020 |
Park SJ, Riccio RE, Kopp SJ, Ifergan I, Miller SD, Longnecker R. Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection. Mbio. 11. PMID 32398314 DOI: 10.1128/Mbio.00790-20 |
0.399 |
|
2020 |
Hippler DP, Fan Q, Longnecker R, Connolly SA. Selection of Mutations that Affect Herpesvirus Entry into Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09212 |
0.307 |
|
2019 |
Chen J, Longnecker R. Epithelial cell infection by Epstein-Barr virus. Fems Microbiology Reviews. PMID 31584659 DOI: 10.1093/Femsre/Fuz023 |
0.554 |
|
2019 |
Möhl BS, Chen J, Longnecker R. Gammaherpesvirus entry and fusion: A tale how two human pathogenic viruses enter their host cells. Advances in Virus Research. 104: 313-343. PMID 31439152 DOI: 10.1016/Bs.Aivir.2019.05.006 |
0.556 |
|
2019 |
Sora RP, Ikeda M, Longnecker R. Two Pathways of p27 Degradation Are Required for Murine Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A. Mbio. 10. PMID 30992353 DOI: 10.1128/Mbio.00548-19 |
0.365 |
|
2019 |
Chen J, Zhang X, Schaller S, Jardetzky TS, Longnecker R. Ephrin Receptor A4 is a New Kaposi's Sarcoma-Associated Herpesvirus Virus Entry Receptor. Mbio. 10. PMID 30782663 DOI: 10.1128/Mbio.02892-18 |
0.543 |
|
2018 |
Fan Q, Kopp SJ, Byskosh NC, Connolly SA, Longnecker R. Natural Selection of Glycoprotein B Mutations That Rescue the Small-Plaque Phenotype of a Fusion-Impaired Herpes Simplex Virus Mutant. Mbio. 9. PMID 30327436 DOI: 10.1128/Mbio.01948-18 |
0.472 |
|
2018 |
Cen O, Kannan K, Huck Sappal J, Yu J, Zhang M, Arikan M, Ucur A, Ustek D, Cen Y, Gordon L, Longnecker R. Spleen Tyrosine Kinase Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of Epstein-Barr Virus-Associated Lymphoma. Msphere. 3. PMID 30135222 DOI: 10.1128/mSphereDirect.00378-18 |
0.371 |
|
2018 |
Chen J, Sathiyamoorthy K, Zhang X, Schaller S, Perez White BE, Jardetzky TS, Longnecker R. Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus. Nature Microbiology. PMID 29292384 DOI: 10.1038/S41564-017-0081-7 |
0.586 |
|
2017 |
Fish K, Sora RP, Schaller SJ, Longnecker R, Ikeda M. EBV latent membrane protein 2A orchestrates p27(kip1) degradation via Cks1 to accelerate MYC-driven lymphoma in mice. Blood. PMID 29074502 DOI: 10.1182/Blood-2017-07-796821 |
0.727 |
|
2017 |
Möhl BS, Chen J, Park SJ, Jardetzky TS, Longnecker R. Epstein-Barr virus fusion with epithelial cells triggered by gB is restricted by a gL glycosylation site. Journal of Virology. PMID 28956769 DOI: 10.1128/Jvi.01255-17 |
0.579 |
|
2017 |
Sathiyamoorthy K, Jiang J, Möhl BS, Chen J, Zhou ZH, Longnecker R, Jardetzky TS. Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 28939750 DOI: 10.1073/Pnas.1704661114 |
0.514 |
|
2017 |
Rink JS, Yang S, Cen O, Taxter T, McMahon KM, Misener S, Behdad A, Longnecker R, Gordon LI, Thaxton CS. Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled by Functional Lipoprotein Nanoparticles: A Therapeutic Strategy Dependent on Cell of Origin. Molecular Pharmaceutics. PMID 28933554 DOI: 10.1021/Acs.Molpharmaceut.7B00710 |
0.334 |
|
2017 |
Sathiyamoorthy K, Chen J, Longnecker R, Jardetzky TS. The COMPLEXity in herpesvirus entry. Current Opinion in Virology. 24: 97-104. PMID 28538165 DOI: 10.1016/J.Coviro.2017.04.006 |
0.494 |
|
2017 |
Fan Q, Kopp SJ, Connolly SA, Longnecker R. Structure-Based Mutations in the Herpes Simplex Virus 1 Glycoprotein B Ectodomain Arm Impart a Slow-Entry Phenotype. Mbio. 8. PMID 28512095 DOI: 10.1128/Mbio.00614-17 |
0.483 |
|
2017 |
Fish K, Longnecker R. EBV germinates lymphoma from the germinal center in a battle with T and NK cells. Proceedings of the National Academy of Sciences of the United States of America. 114: 4571-4573. PMID 28442562 DOI: 10.1073/Pnas.1704102114 |
0.724 |
|
2017 |
Edwards RG, Longnecker R. Herpes virus entry mediator (HVEM) and ocular herpes infection: more than meets the eye. Journal of Virology. PMID 28404853 DOI: 10.1128/Jvi.00115-17 |
0.431 |
|
2017 |
Fan Q, Kopp S, Connolly SA, Muller WJ, Longnecker R. Mapping sites of herpes simplex virus type 1 glycoprotein D that permit insertions and impact gD and gB receptors usage. Scientific Reports. 7: 43712. PMID 28255168 DOI: 10.1038/Srep43712 |
0.427 |
|
2017 |
Edwards RG, Kopp SJ, Ifergan I, Shui JW, Kronenberg M, Miller SD, Longnecker R. Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy. Investigative Ophthalmology & Visual Science. 58: 282-291. PMID 28114589 DOI: 10.1167/Iovs.16-20668 |
0.414 |
|
2016 |
Chen J, Jardetzky TS, Longnecker R. The Cytoplasmic Tail Domain of Epstein-Barr Virus gH Regulates Membrane Fusion Activity through Altering gH Binding to gp42 and Epithelial Cell Attachment. Mbio. 7. PMID 27935841 DOI: 10.1128/Mbio.01871-16 |
0.539 |
|
2016 |
Sathiyamoorthy K, Hu YX, Möhl BS, Chen J, Longnecker R, Jardetzky TS. Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins. Nature Communications. 7: 13557. PMID 27929061 DOI: 10.1038/Ncomms13557 |
0.555 |
|
2016 |
Möhl BS, Chen J, Sathiyamoorthy K, Jardetzky TS, Longnecker R. Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus. Molecules and Cells. PMID 27094060 DOI: 10.14348/Molcells.2016.0066 |
0.576 |
|
2016 |
Wilcox DR, Folmsbee SS, Muller WJ, Longnecker R. The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis. Mbio. 7. PMID 27073094 DOI: 10.1128/Mbio.00437-16 |
0.383 |
|
2016 |
Yigit B, Halibozek PJ, Chen SS, O'Keeffe MS, Arnason J, Avigan D, Gattei V, Bhan A, Cen O, Longnecker R, Chiorazzi N, Wang N, Engel P, Terhorst C. A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cells. Oncotarget. PMID 27029059 DOI: 10.18632/Oncotarget.8378 |
0.443 |
|
2016 |
Wilcox DR, Longnecker R. The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus-Host Interactions. Plos Pathogens. 12: e1005449. PMID 26964062 DOI: 10.1371/Journal.Ppat.1005449 |
0.434 |
|
2016 |
Cen O, Kannan K, Huck JJ, Yu J, Zhang M, Gordon LI, Longnecker R. The Syk Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of EBV-Associated Lymphoma Blood. 128: 4179-4179. DOI: 10.1182/Blood.V128.22.4179.4179 |
0.412 |
|
2015 |
Möhl BS, Schröter C, Klupp BG, Fuchs W, Mettenleiter TC, Jardetzky TS, Longnecker R. Comparative mutagenesis of Pseudorabies and Epstein-Barr virus gH identifies a structural determinant within domain III of gH required for surface expression and entry function. Journal of Virology. PMID 26656711 DOI: 10.1128/Jvi.03032-15 |
0.51 |
|
2015 |
Wilcox DR, Muller WJ, Longnecker R. HSV targeting of the host phosphatase PP1α is required for disseminated disease in the neonate and contributes to pathogenesis in the brain. Proceedings of the National Academy of Sciences of the United States of America. 112: E6937-44. PMID 26621722 DOI: 10.1073/Pnas.1513045112 |
0.415 |
|
2015 |
Edwards RG, Kopp SJ, Karaba AH, Wilcox DR, Longnecker R. Herpesvirus Entry Mediator on Radiation-Resistant Cell Lineages Promotes Ocular Herpes Simplex Virus 1 Pathogenesis in an Entry-Independent Manner. Mbio. 6. PMID 26489863 DOI: 10.1128/Mbio.01532-15 |
0.743 |
|
2015 |
Cen O, Longnecker RM. Latent Membrane Protein 2 (LMP2). Current Topics in Microbiology and Immunology. 391: 151-180. PMID 26428374 DOI: 10.1007/978-3-319-22834-1_5 |
0.433 |
|
2015 |
Zhao M, Onakpa MM, Santarsiero BD, Huang XJ, Zhang XQ, Chen J, Cheng JJ, Longnecker R, Che CT. Icacinlactone H and Icacintrichantholide from the Tuber of Icacina trichantha. Organic Letters. PMID 26183449 DOI: 10.1021/Acs.Orglett.5B01806 |
0.306 |
|
2015 |
Fan Q, Longnecker R, Connolly SA. A Functional Interaction between Herpes Simplex Virus 1 Glycoprotein gH/gL Domains I and II and gD Is Defined by Using Alphaherpesvirus gH and gL Chimeras. Journal of Virology. 89: 7159-69. PMID 25926636 DOI: 10.1128/Jvi.00740-15 |
0.487 |
|
2015 |
Wilcox DR, Wadhwani NR, Longnecker R, Muller WJ. Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults Plos Pathogens. 11: e1004580. PMID 25569138 DOI: 10.1371/Journal.Ppat.1004580 |
0.352 |
|
2015 |
Rowe CL, Chen J, Jardetzky TS, Longnecker R. Membrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers. Mbio. 6. PMID 25564465 DOI: 10.1128/Mbio.02285-14 |
0.51 |
|
2015 |
Rowe CL, Chen J, Jardetzky TS, Longnecker R. Membrane anchoring of epstein-barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers Mbio. 6. DOI: 10.1128/mBio.02285-14 |
0.43 |
|
2014 |
Möhl BS, Sathiyamoorthy K, Jardetzky TS, Longnecker R. The conserved disulfide bond within domain II of Epstein-Barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells. Journal of Virology. 88: 13570-9. PMID 25231307 DOI: 10.1128/Jvi.02272-14 |
0.592 |
|
2014 |
Sathiyamoorthy K, Jiang J, Hu YX, Rowe CL, Möhl BS, Chen J, Jiang W, Mellins ED, Longnecker R, Zhou ZH, Jardetzky TS. Assembly and architecture of the EBV B cell entry triggering complex. Plos Pathogens. 10: e1004309. PMID 25144748 DOI: 10.1371/Journal.Ppat.1004309 |
0.587 |
|
2014 |
Chen J, Zhang X, Jardetzky TS, Longnecker R. The Epstein-Barr virus (EBV) glycoprotein B cytoplasmic C-terminal tail domain regulates the energy requirement for EBV-induced membrane fusion Journal of Virology. 88: 11686-11695. PMID 25100836 DOI: 10.1128/Jvi.01349-14 |
0.555 |
|
2014 |
Fan Q, Longnecker R, Connolly SA. Substitution of herpes simplex virus 1 entry glycoproteins with those of saimiriine herpesvirus 1 reveals a gD-gH/gL functional interaction and a region within the gD profusion domain that is critical for fusion. Journal of Virology. 88: 6470-82. PMID 24672037 DOI: 10.1128/Jvi.00465-14 |
0.474 |
|
2014 |
Fish K, Chen J, Longnecker R. Epstein-Barr virus latent membrane protein 2A enhances MYC-driven cell cycle progression in a mouse model of B lymphoma. Blood. 123: 530-40. PMID 24174629 DOI: 10.1182/Blood-2013-07-517649 |
0.72 |
|
2014 |
Möhl BS, Sathiyamoorthy K, Jardetzky TS, Longnecker R. The conserved disulfide bond within domain II of epstein-barr virus gH has divergent roles in membrane fusion with epithelial cells and B cells Journal of Virology. 88: 13570-13579. DOI: 10.1128/JVI.02272-14 |
0.445 |
|
2013 |
Brägelmann J, Dagogo-Jack I, El Dinali M, Stricker T, Brown CD, Zuo Z, Khattri A, Keck M, McNerney ME, Longnecker R, Bieging K, Kocherginsky M, Alexander K, Salgia R, Lingen MW, et al. Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA. Oral Oncology. 49: 525-33. PMID 23490885 DOI: 10.1016/J.Oraloncology.2013.02.003 |
0.764 |
|
2013 |
Fan Q, Bohannon KP, Longnecker R. Drosophila Schneider 2 (S2) cells: a novel tool for studying HSV-induced membrane fusion. Virology. 437: 100-9. PMID 23399037 DOI: 10.1016/J.Virol.2013.01.004 |
0.444 |
|
2013 |
Garcia NJ, Chen J, Longnecker R. Modulation of Epstein-Barr Virus Glycoprotein B (gB) Fusion Activity by the gB Cytoplasmic Tail Domain Mbio. 4. PMID 23341550 DOI: 10.1128/Mbio.00571-12 |
0.576 |
|
2013 |
Rowe CL, Connolly SA, Chen J, Jardetzky TS, Longnecker R. A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion Virology. 436: 118-126. PMID 23200314 DOI: 10.1016/J.Virol.2012.10.039 |
0.493 |
|
2013 |
Zago A, Connolly SA, Spear PG, Longnecker R. The fusion loops and membrane proximal region of Epstein-Barr virus glycoprotein B (gB) can function in the context of herpes simplex virus 1 gB when substituted individually but not in combination. Virus Research. 171: 227-30. PMID 23089849 DOI: 10.1016/J.Virusres.2012.10.015 |
0.506 |
|
2012 |
Karaba AH, Kopp SJ, Longnecker R. Herpesvirus entry mediator is a serotype specific determinant of pathogenesis in ocular herpes. Proceedings of the National Academy of Sciences of the United States of America. 109: 20649-54. PMID 23184983 DOI: 10.1073/Pnas.1216967109 |
0.705 |
|
2012 |
Shim AH, Chang RA, Chen X, Longnecker R, He X. Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1. Proceedings of the National Academy of Sciences of the United States of America. 109: 12962-7. PMID 22826234 DOI: 10.1073/Pnas.1205309109 |
0.752 |
|
2012 |
Fan Q, Longnecker R. Is nectin-1 the "master" receptor for deadly herpes B virus infection? Virulence. 3: 405. PMID 22722246 DOI: 10.4161/Viru.20587 |
0.498 |
|
2012 |
Chang RA, Miller SD, Longnecker R. Epstein-Barr virus latent membrane protein 2A exacerbates experimental autoimmune encephalomyelitis and enhances antigen presentation function. Scientific Reports. 2: 353. PMID 22616025 DOI: 10.1038/Srep00353 |
0.824 |
|
2012 |
Dargart JL, Fish K, Gordon LI, Longnecker R, Cen O. Dasatinib therapy results in decreased B cell proliferation, splenomegaly, and tumor growth in a murine model of lymphoma expressing Myc and Epstein-Barr virus LMP2A. Antiviral Research. 95: 49-56. PMID 22609829 DOI: 10.1016/J.Antiviral.2012.05.003 |
0.716 |
|
2012 |
Gordon LI, Longnecker R. Off-targeting oft-targeted CD20 in cHL. Blood. 119: 4095-4096. PMID 22555658 DOI: 10.1182/Blood-2012-03-413146 |
0.427 |
|
2012 |
Vrazo AC, Chauchard M, Raab-Traub N, Longnecker R. Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice. Plos Pathogens. 8. PMID 22536156 DOI: 10.1371/Journal.Ppat.1002662 |
0.596 |
|
2012 |
Connolly SA, Longnecker R. Residues within the C-terminal arm of the herpes simplex virus 1 glycoprotein B ectodomain contribute to its refolding during the fusion step of virus entry. Journal of Virology. 86: 6386-93. PMID 22491468 DOI: 10.1128/Jvi.00104-12 |
0.514 |
|
2012 |
Fan Q, Amen M, Harden M, Severini A, Griffiths A, Longnecker RM. Herpes B Virus Utilizes Human Nectin-1 but Not HVEM or PILRα for Cell-Cell Fusion and Virus Entry Journal of Virology. 86: 4468-4476. PMID 22345445 DOI: 10.1128/Jvi.00041-12 |
0.556 |
|
2012 |
Chen J, Rowe CL, Jardetzky TS, Longnecker R. The KGD motif of Epstein-Barr virus gH/gL is bifunctional, orchestrating infection of B cells and epithelial cells. Mbio. 3. PMID 22215569 DOI: 10.1128/Mbio.00290-11 |
0.609 |
|
2011 |
Bieging KT, Fish K, Bondada S, Longnecker R. A shared gene expression signature in mouse models of EBV-associated and non-EBV-associated Burkitt lymphoma. Blood. 118: 6849-59. PMID 22039254 DOI: 10.1182/Blood-2011-02-338434 |
0.815 |
|
2011 |
Karaba AH, Kopp SJ, Longnecker R. Herpesvirus entry mediator and nectin-1 mediate herpes simplex virus 1 infection of the murine cornea. Journal of Virology. 85: 10041-7. PMID 21795335 DOI: 10.1128/Jvi.05445-11 |
0.716 |
|
2011 |
Rowe CL, Matsuura H, Jardetzky TS, Longnecker R. Investigation of the function of the putative self-association site of Epstein-Barr virus (EBV) glycoprotein 42 (gp42) Virology. 415: 122-131. PMID 21550622 DOI: 10.1016/J.Virol.2011.04.003 |
0.469 |
|
2011 |
Connolly SA, Jackson JO, Jardetzky TS, Longnecker R. Fusing structure and function: A structural view of the herpesvirus entry machinery Nature Reviews Microbiology. 9: 369-381. PMID 21478902 DOI: 10.1038/Nrmicro2548 |
0.497 |
|
2011 |
Plate AE, Reimer JJ, Jardetzky TS, Longnecker R. Mapping regions of Epstein-Barr virus (EBV) glycoprotein B (gB) important for fusion function with gH/gL. Virology. 413: 26-38. PMID 21376360 DOI: 10.1016/J.Virol.2010.12.006 |
0.827 |
|
2011 |
Cen O, Longnecker RM. Rapamycin Reverses Splenomegaly and Inhibits Tumor Development in a Transgenic Model of Epstein-Barr Virus–Related Burkitt's Lymphoma Molecular Cancer Therapeutics. 10: 679-686. PMID 21282357 DOI: 10.1158/1535-7163.Mct-10-0833 |
0.433 |
|
2010 |
Matsuura H, Kirschner AN, Longnecker R, Jardetzky TS. Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex Proceedings of the National Academy of Sciences of the United States of America. 107: 22641-22646. PMID 21149717 DOI: 10.1073/Pnas.1011806108 |
0.534 |
|
2010 |
Jackson JO, Longnecker R. Reevaluating herpes simplex virus hemifusion. Journal of Virology. 84: 11814-11821. PMID 20844038 DOI: 10.1128/Jvi.01615-10 |
0.513 |
|
2010 |
Liu F, Marquardt G, Kirschner AN, Longnecker R, Jardetzky TS. Mapping the N-terminal residues of Epstein-Barr virus gp42 that bind gH/gL by using fluorescence polarization and cell-based fusion assays Journal of Virology. 84: 10375-10385. PMID 20668073 DOI: 10.1128/Jvi.00381-10 |
0.533 |
|
2010 |
Fan Q, Longnecker R. The Ig-like V-type domain of paired Ig-like type 2 receptor alpha is critical for herpes simplex virus type 1-mediated membrane fusion Journal of Virology. 84: 8664-8672. PMID 20573830 DOI: 10.1128/Jvi.01039-10 |
0.419 |
|
2010 |
Swanson-Mungerson M, Bultema R, Longnecker R. Epstein–Barr virus LMP2A imposes sensitivity to apoptosis Journal of General Virology. 91: 2197-2202. PMID 20484564 DOI: 10.1099/Vir.0.021444-0 |
0.525 |
|
2010 |
Shaw PL, Kirschner AN, Jardetzky TS, Longnecker R. Characteristics of Epstein-Barr virus envelope protein gp42 Virus Genes. 40: 307-319. PMID 20162447 DOI: 10.1007/S11262-010-0455-X |
0.513 |
|
2010 |
Bieging KT, Swanson-Mungerson M, Amick AC, Longnecker R. Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2A. Cell Cycle (Georgetown, Tex.). 9: 901-8. PMID 20160479 DOI: 10.4161/Cc.9.5.10840 |
0.825 |
|
2010 |
Jackson JO, Lin E, Spear PG, Longnecker R. Insertion mutations in herpes simplex virus 1 glycoprotein H reduce cell surface expression, slow the rate of cell fusion, or abrogate functions in cell fusion and viral entry. Journal of Virology. 84: 2038-46. PMID 20007280 DOI: 10.1128/Jvi.02215-09 |
0.507 |
|
2009 |
Bieging KT, Amick AC, Longnecker R. Epstein-Barr virus LMP2A bypasses p53 inactivation in a MYC model of lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 17945-50. PMID 19815507 DOI: 10.1073/Pnas.0907994106 |
0.805 |
|
2009 |
Plate AE, Smajlovi? J, Jardetzky TS, Longnecker R. Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion Journal of Virology. 83: 7678-7689. PMID 19457993 DOI: 10.1128/Jvi.00457-09 |
0.838 |
|
2009 |
Sorem J, Jardetzky TS, Longnecker R. Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes Journal of Virology. 83: 6664-6672. PMID 19369343 DOI: 10.1128/Jvi.00195-09 |
0.833 |
|
2009 |
Sorem J, Longnecker R. Cleavage of Epstein-Barr virus glycoprotein B is required for full function in cell-cell fusion with both epithelial and B cells. The Journal of General Virology. 90: 591-5. PMID 19218203 DOI: 10.1099/Vir.0.007237-0 |
0.824 |
|
2009 |
Kirschner AN, Sorem J, Longnecker R, Jardetzky TS. Structure of Epstein-Barr Virus Glycoprotein 42 Suggests a Mechanism for Triggering Receptor-Activated Virus Entry Structure. 17: 223-233. PMID 19217393 DOI: 10.1016/J.Str.2008.12.010 |
0.802 |
|
2009 |
Backovic M, Longnecker R, Jardetzky TS. Structure of a trimeric variant of the Epstein-Barr virus glycoprotein B Proceedings of the National Academy of Sciences of the United States of America. 106: 2880-2885. PMID 19196955 DOI: 10.1073/Pnas.0810530106 |
0.523 |
|
2009 |
Bultema R, Longnecker R, Swanson-Mungerson M. Epstein-Barr virus LMP2A accelerates MYC-induced lymphomagenesis. Oncogene. 28: 1471-1476. PMID 19182823 DOI: 10.1038/Onc.2008.492 |
0.524 |
|
2009 |
Ikeda M, Longnecker R. The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling. Virology. 385: 183-191. PMID 19081591 DOI: 10.1016/J.Virol.2008.11.018 |
0.483 |
|
2009 |
Hsiao FC, Tai AK, Deglon A, Sutkowski N, Longnecker R, Huber BT. EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM. Virology. 385: 261-6. PMID 19070345 DOI: 10.1016/J.Virol.2008.11.025 |
0.327 |
|
2009 |
Reimer JJ, Backovic M, Deshpande CG, Jardetzky T, Longnecker R. Analysis of Epstein-Barr virus glycoprotein B functional domains via linker insertion mutagenesis. Journal of Virology. 83: 734-47. PMID 18987135 DOI: 10.1128/Jvi.01817-08 |
0.563 |
|
2009 |
Anderson LJ, Longnecker R. Epstein-Barr virus latent membrane protein 2A exploits Notch1 to alter B-cell identity in vivo. Blood. 113: 108-16. PMID 18815281 DOI: 10.1182/Blood-2008-06-160937 |
0.536 |
|
2009 |
Bieging KT, Amick AC, Longnecker R. Abstract B30: EBV LMP2A bypasses p53 inactivation in a MYC model of lymphomagenesis Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B30 |
0.785 |
|
2008 |
Rovedo M, Longnecker R. Epstein-Barr Virus Latent Membrane Protein 2A Preferentially Signals through the Src Family Kinase Lyn Journal of Virology. 82: 8520-8528. PMID 18579586 DOI: 10.1128/Jvi.00843-08 |
0.832 |
|
2008 |
Anderson LJ, Longnecker R. EBV LMP2A provides a surrogate pre-B cell receptor signal through constitutive activation of the ERK/MAPK pathway. The Journal of General Virology. 89: 1563-8. PMID 18559925 DOI: 10.1099/Vir.0.2008/001461-0 |
0.506 |
|
2008 |
Rechsteiner MP, Berger C, Zauner L, Sigrist JA, Weber M, Longnecker R, Bernasconi M, Nadal D. Latent membrane protein 2B regulates susceptibility to induction of lytic Epstein-Barr virus infection. Journal of Virology. 82: 1739-47. PMID 18057232 DOI: 10.1128/Jvi.01723-07 |
0.616 |
|
2008 |
Anderson LJ, Longnecker R. An auto-regulatory loop for EBV LMP2A involves activation of Notch Virology. 371: 257-266. PMID 17980397 DOI: 10.1016/J.Virol.2007.10.009 |
0.391 |
|
2007 |
Zhang M, Veselits M, O'Neill S, Hou P, Reddi AL, Berlin I, Ikeda M, Nash PD, Longnecker R, Band H, Clark MR. Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor. Journal of Immunology (Baltimore, Md. : 1950). 179: 4435-43. PMID 17878339 DOI: 10.4049/Jimmunol.179.7.4435 |
0.377 |
|
2007 |
Backovic M, Leser GP, Lamb RA, Longnecker R, Jardetzky TS. Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins. Virology. 368: 102-13. PMID 17655906 DOI: 10.1016/J.Virol.2007.06.031 |
0.492 |
|
2007 |
Fukuda M, Longnecker R. Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt pathway Journal of Virology. 81: 9299-9306. PMID 17582000 DOI: 10.1128/Jvi.00537-07 |
0.444 |
|
2007 |
Kirschner AN, Lowrey AS, Longnecker R, Jardetzky TS. Binding-site interactions between epstein-barr virus fusion proteins gp42 and gH/gL reveal a peptide that inhibits both epithelial and B-cell membrane fusion Journal of Virology. 81: 9216-9229. PMID 17581996 DOI: 10.1128/Jvi.00575-07 |
0.516 |
|
2007 |
Backovic M, Jardetzky TS, Longnecker R. Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity Journal of Virology. 81: 9596-9600. PMID 17553877 DOI: 10.1128/Jvi.00758-07 |
0.564 |
|
2007 |
Omerović J, Longnecker R. Functional Homology of gHs and gLs from EBV-related γ-herpesviruses for EBV-induced Membrane Fusion Virology. 365: 157-165. PMID 17477951 DOI: 10.1016/J.Virol.2007.03.054 |
0.589 |
|
2007 |
Swanson-Mungerson M, Longnecker RM. Epstein–Barr virus latent membrane protein 2A and autoimmunity Trends in Immunology. 28: 213-218. PMID 17398159 DOI: 10.1016/J.It.2007.03.002 |
0.465 |
|
2007 |
Ikeda M, Longnecker R. Cholesterol is Critical for Epstein-Barr Virus Latent Membrane Protein 2A Trafficking and Protein Stability Virology. 360: 461-468. PMID 17150237 DOI: 10.1016/J.Virol.2006.10.046 |
0.459 |
|
2007 |
Rovedo M, Longnecker R. Epstein-Barr Virus Latent Membrane Protein 2B (LMP2B) Modulates LMP2A Activity Journal of Virology. 81: 84-94. PMID 17035319 DOI: 10.1128/Jvi.01302-06 |
0.845 |
|
2006 |
Kirschner AN, Omerovi? J, Popov B, Longnecker R, Jardetzky TS. Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion Journal of Virology. 80: 9444-9454. PMID 16973550 DOI: 10.1128/Jvi.00572-06 |
0.535 |
|
2006 |
Swanson-Mungerson M, Bultema R, Longnecker R. Epstein-Barr Virus LMP2A Enhances B-Cell Responses In Vivo and In Vitro Journal of Virology. 80: 6764-6770. PMID 16809282 DOI: 10.1128/Jvi.00433-06 |
0.516 |
|
2006 |
Lu J, Lin WH, Chen SY, Longnecker R, Tsai SC, Chen CL, Tsai CH. Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells. The Journal of Biological Chemistry. 281: 8806-14. PMID 16431925 DOI: 10.1074/Jbc.M507305200 |
0.504 |
|
2005 |
Omerović J, Lev L, Longnecker R. The Amino Terminus of Epstein-Barr Virus Glycoprotein gH Is Important for Fusion with Epithelial and B Cells Journal of Virology. 79: 12408-12415. PMID 16160168 DOI: 10.1128/Jvi.79.19.12408-12415.2005 |
0.581 |
|
2005 |
Fukuda M, Longnecker RM. Epstein-Barr Virus (EBV) Latent Membrane Protein 2A Regulates B-Cell Receptor-Induced Apoptosis and EBV Reactivation through Tyrosine Phosphorylation Journal of Virology. 79: 8655-8660. PMID 15956608 DOI: 10.1128/Jvi.79.13.8655-8660.2005 |
0.53 |
|
2005 |
Swanson-Mungerson MA, Caldwell RG, Bultema R, Longnecker RM. Epstein-Barr Virus LMP2A Alters In Vivo and In Vitro Models of B-Cell Anergy, but Not Deletion, in Response to Autoantigen Journal of Virology. 79: 7355-7362. PMID 15919890 DOI: 10.1128/Jvi.79.12.7355-7362.2005 |
0.554 |
|
2005 |
Stefan M, Portis T, Longnecker R, Nicholls RD. A nonimprinted Prader-Willi Syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted PWS loci do not alter genome-wide mRNA levels Genomics. 85: 630-640. PMID 15820315 DOI: 10.1016/J.Ygeno.2005.02.004 |
0.305 |
|
2005 |
Park SJ, Seo MD, Lee SK, Ikeda M, Longnecker R, Lee BJ. Expression and characterization of N-terminal domain of Epstein-Barr virus latent membrane protein 2A in Escherichia coli. Protein Expression and Purification. 41: 9-17. PMID 15802216 DOI: 10.1016/J.Pep.2004.07.006 |
0.478 |
|
2005 |
Ikeda M, Longnecker RM. Pre-B-cell colony formation assay. Methods of Molecular Biology. 292: 279-283. PMID 15507715 DOI: 10.1385/1-59259-848-X:279 |
0.507 |
|
2005 |
McShane MP, Longnecker R. Analysis of fusion using a virus-free cell fusion assay. Methods in Molecular Biology (Clifton, N.J.). 292: 187-96. PMID 15507709 DOI: 10.1385/1-59259-848-X:187 |
0.849 |
|
2004 |
McShane MP, Longnecker R. Cell-surface expression of a mutated Epstein-Barr virus glycoprotein B allows fusion independent of other viral proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 17474-9. PMID 15583133 DOI: 10.1073/Pnas.0404535101 |
0.855 |
|
2004 |
Katzman RB, Longnecker R. LMP2A does not require palmitoylation to localize to buoyant complexes or for function. Journal of Virology. 78: 10878-87. PMID 15452208 DOI: 10.1128/Jvi.78.20.10878-10887.2004 |
0.772 |
|
2004 |
Portis T, Longnecker RM. Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway. Oncogene. 23: 8619-8628. PMID 15361852 DOI: 10.1038/Sj.Onc.1207905 |
0.488 |
|
2004 |
Portis T, Ikeda M, Longnecker RM. Epstein-Barr virus LMP2A: regulating cellular ubiquitination processes for maintenance of viral latency? Trends in Immunology. 25: 422-426. PMID 15275641 DOI: 10.1016/J.It.2004.05.009 |
0.553 |
|
2004 |
Silva AL, Omerovi? J, Jardetzky TS, Longnecker R. Mutational analyses of Epstein-Barr virus glycoprotein 42 reveal functional domains not involved in receptor binding but required for membrane fusion Journal of Virology. 78: 5946-5956. PMID 15140992 DOI: 10.1128/Jvi.78.11.5946-5956.2004 |
0.511 |
|
2004 |
Ikeda A, Merchant M, Lev L, Longnecker R, Ikeda M. Latent membrane protein 2A, a viral B cell receptor homologue, induces CD5+ B-1 cell development. Journal of Immunology. 172: 5329-5337. PMID 15100272 DOI: 10.4049/Jimmunol.172.9.5329 |
0.73 |
|
2004 |
Shaikh S, Skoczylas C, Longnecker R, Rundell K. Inability of simian virus 40 to establish productive infection of lymphoblastic cell lines. Journal of Virology. 78: 4917-20. PMID 15078974 DOI: 10.1128/Jvi.78.9.4917-4920.2004 |
0.455 |
|
2004 |
Portis T, Longnecker R. Epstein-Barr virus (EBV) LMP2A alters normal transcriptional regulation following B-cell receptor activation. Virology. 318: 524-533. PMID 14972521 DOI: 10.1016/J.Virol.2003.09.017 |
0.548 |
|
2004 |
Fukuda M, Longnecker R. Latent Membrane Protein 2A Inhibits Transforming Growth Factor-β1-Induced Apoptosis through the Phosphatidylinositol 3-Kinase/Akt Pathway Journal of Virology. 78: 1697-1705. PMID 14747535 DOI: 10.1128/Jvi.78.4.1697-1705.2004 |
0.374 |
|
2003 |
Katzman RB, Longnecker R. Cholesterol-dependent infection of Burkitt's lymphoma cell lines by Epstein-Barr virus. The Journal of General Virology. 84: 2987-92. PMID 14573803 DOI: 10.1099/Vir.0.19252-0 |
0.811 |
|
2003 |
Ressing ME, Van Leeuwen D, Verreck FAW, Gomez R, Heemskerk B, Toebes M, Mullen MM, Jardetzky TS, Longnecker R, Schilham MW, Ottenhoff THM, Neefjes J, Schumacher TN, Hutt-Fletcher LM, Wiertz EJHJ. Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition Proceedings of the National Academy of Sciences of the United States of America. 100: 11583-11588. PMID 14504389 DOI: 10.1073/Pnas.2034960100 |
0.476 |
|
2003 |
Spear PG, Longnecker R. Herpesvirus entry: an update. Journal of Virology. 77: 10179-85. PMID 12970403 DOI: 10.1128/Jvi.77.19.10179-10185.2003 |
0.498 |
|
2003 |
Speck P, Callen DF, Longnecker R. Absence of the Epstein-Barr virus genome in breast cancer-derived cell lines. Journal of the National Cancer Institute. 95: 1253-4; author reply. PMID 12928356 DOI: 10.1093/Jnci/Djg041 |
0.354 |
|
2003 |
Portis T, Dyck P, Longnecker R. Epstein-Barr Virus (EBV) LMP2A induces alterations in gene transcription similar to those observed in Reed-Sternberg cells of Hodgkin lymphoma. Blood. 102: 4166-4178. PMID 12907455 DOI: 10.1182/Blood-2003-04-1018 |
0.558 |
|
2003 |
Swanson-Mungerson M, Ikeda M, Lev L, Longnecker R, Portis T. Identification of latent membrane protein 2A (LMP2A) specific targets for treatment and eradication of Epstein–Barr virus (EBV)-associated diseases Journal of Antimicrobial Chemotherapy. 52: 152-154. PMID 12837743 DOI: 10.1093/Jac/Dkg306 |
0.407 |
|
2003 |
McShane MP, Mullen MM, Haan KM, Jardetzky TS, Longnecker R. Mutational analysis of the HLA class II interaction with Epstein-Barr virus glycoprotein 42 Journal of Virology. 77: 7655-7662. PMID 12805465 DOI: 10.1128/Jvi.77.13.7655-7662.2003 |
0.778 |
|
2003 |
Ikeda A, Caldwell RG, Longnecker R, Ikeda M. Itchy, a Nedd4 ubiquitin ligase, downregulates latent membrane protein 2A activity in B-cell signaling. Journal of Virology. 77: 5529-5534. PMID 12692257 DOI: 10.1128/Jvi.77.9.5529-5534.2003 |
0.464 |
|
2003 |
Portis T, Longnecker R. Epstein-Barr Virus LMP2A Interferes with Global Transcription Factor Regulation When Expressed during B-Lymphocyte Development Journal of Virology. 77: 105-114. PMID 12477815 DOI: 10.1128/Jvi.77.1.105-114.2003 |
0.527 |
|
2002 |
Cooper L, Longnecker RM. Inhibition of host kinase activity altered by the LMP2A signalosome-a therapeutic target for Epstein-Barr virus latency and associated disease. Antiviral Research. 56: 219-231. PMID 12406506 DOI: 10.1016/S0166-3542(02)00110-9 |
0.486 |
|
2002 |
Ikeda M, Ikeda A, Longnecker R. Lysine-independent ubiquitination of Epstein-Barr virus LMP2A. Virology. 300: 153-159. PMID 12202215 DOI: 10.1006/Viro.2002.1562 |
0.456 |
|
2002 |
Inabe K, Miyawaki T, Longnecker R, Matsukura H, Tsukada S, Kurosaki T. Bruton's tyrosine kinase regulates B cell antigen receptor-mediated JNK1 response through Rac1 and phospholipase C-γ2 activation Febs Letters. 514: 260-262. PMID 11943162 DOI: 10.1016/S0014-5793(02)02375-X |
0.398 |
|
2002 |
Mullen MM, Haan KM, Longnecker R, Jardetzky TS. Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1 Molecular Cell. 9: 375-385. PMID 11864610 DOI: 10.1016/S1097-2765(02)00465-3 |
0.818 |
|
2002 |
Portis T, Cooper L, Dennis P, Longnecker R. The LMP2A signalosome--a therapeutic target for Epstein-Barr virus latency and associated disease. Frontiers in Bioscience : a Journal and Virtual Library. 7: d414-26. PMID 11815296 DOI: 10.2741/Portis |
0.52 |
|
2002 |
Speck P, Ikeda M, Ikeda A, Lederman HM, Longnecker R. Signal transduction through the B cell antigen receptor is normal in ataxia-telangiectasia B lymphocytes. Journal of Biological Chemistry. 277: 4123-4127. PMID 11733529 DOI: 10.1074/Jbc.M110109200 |
0.476 |
|
2001 |
Merchant M, Swart R, Katzman RB, Ikeda M, Ikeda A, Longnecker R, Dykstra ML, Pierce SK. The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function. International Reviews of Immunology. 20: 805-35. PMID 11913951 DOI: 10.3109/08830180109045591 |
0.838 |
|
2001 |
Haan KM, Kyeong Lee S, Longnecker R. Different functional domains in the cytoplasmic tail of glycoprotein B are involved in Epstein-Barr virus-induced membrane fusion Virology. 290: 106-114. PMID 11882994 DOI: 10.1006/Viro.2001.1141 |
0.845 |
|
2001 |
Scholle F, Longnecker R, Raab-Traub N. Analysis of the Phosphorylation Status of Epstein–Barr Virus LMP2A in Epithelial Cells Virology. 291: 208-214. PMID 11878890 DOI: 10.1006/Viro.2001.1197 |
0.383 |
|
2001 |
Merchant M, Longnecker R. LMP2A survival and developmental signals are transmitted through Btk-dependent and Btk-independent pathways Virology. 291: 46-54. PMID 11878875 DOI: 10.1006/Viro.2001.1187 |
0.736 |
|
2001 |
Dawson CW, George JH, Blake SMS, Longnecker RM, Young LS. The Epstein–Barr Virus Encoded Latent Membrane Protein 2A Augments Signaling from Latent Membrane Protein 1 Virology. 289: 192-207. PMID 11689042 DOI: 10.1006/Viro.2001.1142 |
0.479 |
|
2001 |
Engels N, Merchant M, Pappu R, Chan AC, Longnecker R, Wienands J. Epstein-Barr Virus Latent Membrane Protein 2a (Lmp2a) Employs the Slp-65 Signaling Module Journal of Experimental Medicine. 194: 255-264. PMID 11489945 DOI: 10.1084/Jem.194.3.255 |
0.728 |
|
2001 |
Gahn B, Siller-Lopez F, Pirooz AD, Yvon E, Gottschalk S, Longnecker R, Brenner MK, Heslop HE, Aguilar-Cordova E, Rooney CM. Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen : A potential treatment strategy for Epstein-Barr virus-positive Hodgkin's lymphoma International Journal of Cancer. 93: 706-713. PMID 11477583 DOI: 10.1002/Ijc.1396 |
0.377 |
|
2001 |
Ikeda M, Ikeda A, Longnecker R. PY Motifs of Epstein-Barr Virus LMP2A Regulate Protein Stability and Phosphorylation of LMP2A-Associated Proteins Journal of Virology. 75: 5711-5718. PMID 11356981 DOI: 10.1128/Jvi.75.12.5711-5718.2001 |
0.54 |
|
2001 |
Haan KM, Aiyar A, Longnecker R. Establishment of latent Epstein-Barr virus infection and stable episomal maintenance in murine B-cell lines Journal of Virology. 75: 3016-3020. PMID 11222728 DOI: 10.1128/Jvi.75.6.3016-3020.2001 |
0.85 |
|
2001 |
Dykstra ML, Longnecker R, Pierce SK. Epstein-Barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR. Immunity. 14: 57-67. PMID 11163230 DOI: 10.1016/S1074-7613(01)00089-9 |
0.463 |
|
2000 |
Speck P, Longnecker R. Infection of breast epithelial cells with epstein-barr virus via cell-to-cell contact Journal of the National Cancer Institute. 92: 1849-1851. PMID 11078764 DOI: 10.1093/Jnci/92.22.1849 |
0.446 |
|
2000 |
Speck P, Haan KM, Longnecker R. Epstein-Barr virus entry into cells Virology. 277: 1-5. PMID 11062029 DOI: 10.1006/Viro.2000.0624 |
0.812 |
|
2000 |
Swart R, Ruf IK, Sample J, Longnecker R. Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-kinase/Akt pathway Journal of Virology. 74: 10838-10845. PMID 11044134 DOI: 10.1128/Jvi.74.22.10838-10845.2000 |
0.833 |
|
2000 |
Merchant M, Caldwell RG, Longnecker R. The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo Journal of Virology. 74: 9115-9124. PMID 10982358 DOI: 10.1128/Jvi.74.19.9115-9124.2000 |
0.729 |
|
2000 |
Longan L, Longnecker R. Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epithelia. Journal of General Virology. 81: 2245-2252. PMID 10950982 DOI: 10.1099/0022-1317-81-9-2245 |
0.47 |
|
2000 |
Haan KM, Longnecker R. Coreceptor restriction within the HLA-DQ locus for Epstein-Barr virus infection Proceedings of the National Academy of Sciences of the United States of America. 97: 9252-9257. PMID 10908662 DOI: 10.1073/Pnas.160171697 |
0.825 |
|
2000 |
Longnecker R, Merchant M, Brown ME, Fruehling S, Bickford JO, Ikeda M, Harty RN. WW- and SH3-domain interactions with epstein-barr virus LMP2A Experimental Cell Research. 257: 332-340. PMID 10837147 DOI: 10.1006/Excr.2000.4900 |
0.669 |
|
2000 |
Longnecker R. Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence? Advances in Cancer Research. 79: 175-200. PMID 10818681 DOI: 10.1016/S0065-230X(00)79006-3 |
0.522 |
|
2000 |
Ikeda M, Ikeda A, Longan LC, Longnecker R. The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases. Virology. 268: 178-191. PMID 10683340 DOI: 10.1006/Viro.1999.0166 |
0.528 |
|
2000 |
Haan KM, Kwok WW, Longnecker R, Speck P. Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor Journal of Virology. 74: 2451-2454. PMID 10666279 DOI: 10.1128/Jvi.74.5.2451-2454.2000 |
0.826 |
|
2000 |
Caldwell RG, Brown RC, Longnecker R. Epstein-Barr Virus LMP2A-Induced B-Cell Survival in Two Unique Classes of EμLMP2A Transgenic Mice Journal of Virology. 74: 1101-1113. PMID 10627520 DOI: 10.1128/Jvi.74.3.1101-1113.2000 |
0.598 |
|
1999 |
Swart R, Fruehling S, Longnecker RM. Tyrosines 60, 64, and 101 of Epstein–Barr Virus LMP2A Are Not Essential for Blocking B Cell Signal Transduction Virology. 263: 485-495. PMID 10544120 DOI: 10.1006/Viro.1999.9964 |
0.84 |
|
1999 |
Speck P, Kline KA, Cheresh P, Longnecker R. Epstein-Barr virus lacking latent membrane protein 2 immortalizes B cells with efficiency indistinguishable from that of wild-type virus. The Journal of General Virology. 80: 2193-203. PMID 10466819 DOI: 10.1099/0022-1317-80-8-2193 |
0.553 |
|
1999 |
Speck P, Longnecker RM. Epstein-Barr virus (EBV) infection visualized by EGFP expression demonstrates dependence on known mediators of EBV entry Archives of Virology. 144: 1123-1137. PMID 10446648 DOI: 10.1007/S007050050574 |
0.514 |
|
1999 |
Gabriel JM, Merchant M, Ohta T, Ji Y, Caldwell RG, Ramsey MJ, Tucker JD, Longnecker R, Nicholls RD. A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes. Proceedings of the National Academy of Sciences of the United States of America. 96: 9258-63. PMID 10430930 DOI: 10.1073/Pnas.96.16.9258 |
0.606 |
|
1999 |
Scholle F, Longnecker R, Raab-Traub N. Epithelial cell adhesion to extracellular matrix proteins induces tyrosine phosphorylation of the Epstein-Barr virus latent membrane protein 2: a role for C-terminal Src kinase. Journal of Virology. 73: 4767-4775. PMID 10233937 DOI: 10.1128/Jvi.73.6.4767-4775.1999 |
0.472 |
|
1999 |
Kaye KM, Izumi KM, Li H, Johannsen E, Davidson D, Longnecker R, Kieff E. An Epstein-Barr Virus That Expresses Only the First 231 LMP1 Amino Acids Efficiently Initiates Primary B-Lymphocyte Growth Transformation Journal of Virology. 73: 10525-10530. DOI: 10.1128/Jvi.73.12.10525-10530.1999 |
0.489 |
|
1998 |
Pertel PE, Spear PG, Longnecker R. Human herpesvirus-8 glycoprotein B interacts with Epstein-Barr virus (EBV) glycoprotein 110 but fails to complement the infectivity of EBV mutants. Virology. 251: 402-13. PMID 9837804 DOI: 10.1006/Viro.1998.9412 |
0.529 |
|
1998 |
Caldwell RG, Wilson JB, Anderson SJ, Longnecker R. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity. 9: 405-11. PMID 9768760 DOI: 10.1016/S1074-7613(00)80623-8 |
0.61 |
|
1998 |
Fruehling S, Swart R, Dolwick KM, Kremmer E, Longnecker RM. Tyrosine 112 of Latent Membrane Protein 2A Is Essential for Protein Tyrosine Kinase Loading and Regulation of Epstein-Barr Virus Latency Journal of Virology. 72: 7796-7806. PMID 9733815 DOI: 10.1128/Jvi.72.10.7796-7806.1998 |
0.841 |
|
1998 |
Fluckiger AC, Li Z, Kato RM, Wahl MI, Ochs HD, Longnecker R, Kinet JP, Witte ON, Scharenberg AM, Rawlings DJ. Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation. The Embo Journal. 17: 1973-85. PMID 9524120 DOI: 10.1093/Emboj/17.7.1973 |
0.361 |
|
1997 |
Lee SK, Compton T, Longnecker R. Failure to complement infectivity of EBV and HSV-1 glycoprotein B (gB) deletion mutants with gBs from different human herpesvirus subfamilies. Virology. 237: 170-81. PMID 9344919 DOI: 10.1006/Viro.1997.8765 |
0.457 |
|
1997 |
Fruehling S, Longnecker R. The Immunoreceptor Tyrosine-Based Activation Motif of Epstein–Barr Virus LMP2A Is Essential for Blocking BCR-Mediated Signal Transduction☆ Virology. 235: 241-251. PMID 9281504 DOI: 10.1006/Viro.1997.8690 |
0.531 |
|
1997 |
Rochford R, Miller CL, Cannon MJ, Izumi KM, Kieff E, Longnecker R. In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2). Archives of Virology. 142: 707-20. PMID 9170499 DOI: 10.1007/S007050050113 |
0.52 |
|
1997 |
Lee SK, Longnecker R. The Epstein-Barr virus glycoprotein 110 carboxy-terminal tail domain is essential for lytic virus replication. Journal of Virology. 71: 4092-4097. DOI: 10.1128/Jvi.71.5.4092-4097.1997 |
0.477 |
|
1996 |
Longnecker R, Miller CL. Regulation of Epstein-Barr virus latency by latent membrane protein 2. Trends in Microbiology. 4: 38-42. PMID 8824794 DOI: 10.1016/0966-842X(96)81504-6 |
0.543 |
|
1996 |
Fruehling S, Lee SK, Herrold R, Frech B, Laux G, Kremmer E, Grässer FA, Longnecker R. Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction. Journal of Virology. 70: 6216-6226. PMID 8709248 DOI: 10.1128/Jvi.70.9.6216-6226.1996 |
0.479 |
|
1996 |
Herrold RE, Marchini A, Fruehling S, Longnecker R. Glycoprotein 110, the Epstein-Barr virus homolog of herpes simplex virus glycoprotein B, is essential for Epstein-Barr virus replication in vivo. Journal of Virology. 70: 2049-2054. PMID 8627735 DOI: 10.1128/Jvi.70.3.2049-2054.1996 |
0.554 |
|
1995 |
Miller CL, Burkhardt AL, Lee JH, Stealey B, Longnecker R, Bolen JB, Kieff E. Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity. 2: 155-66. PMID 7895172 DOI: 10.1016/S1074-7613(95)80040-9 |
0.442 |
|
1994 |
Miller CL, Lee JH, Kieff E, Longnecker R. An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking. Proceedings of the National Academy of Sciences of the United States of America. 91: 772-6. PMID 8290598 DOI: 10.1073/Pnas.91.2.772 |
0.543 |
|
1993 |
Longnecker R, Miller CL, Tomkinson B, Miao XQ, Kieff E. Deletion of DNA encoding the first five transmembrane domains of Epstein-Barr virus latent membrane proteins 2A and 2B. Journal of Virology. 67: 5068-74. PMID 8392630 DOI: 10.1128/Jvi.67.8.5068-5074.1993 |
0.535 |
|
1993 |
Longnecker R, Miller CL, Miao XQ, Tomkinson B, Kieff E. The last seven transmembrane and carboxy-terminal cytoplasmic domains of Epstein-Barr virus latent membrane protein 2 (LMP2) are dispensable for lymphocyte infection and growth transformation in vitro. Journal of Virology. 67: 2006-13. PMID 8383224 DOI: 10.1128/Jvi.67.4.2006-2013.1993 |
0.526 |
|
1993 |
Tomkinson B, Robertson E, Yalamanchili R, Longnecker R, Kieff E. Epstein-Barr virus recombinants from overlapping cosmid fragments. Journal of Virology. 67: 7298-7306. PMID 8230453 DOI: 10.1128/Jvi.67.12.7298-7306.1993 |
0.414 |
|
1993 |
Miller CL, Longnecker R, Kieff E. Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes. Journal of Virology. 67: 3087-94. PMID 7684459 DOI: 10.1128/Jvi.67.6.3087-3094.1993 |
0.523 |
|
1993 |
Marchini A, Kieff E, Longnecker R. Marker rescue of a transformation-negative Epstein-Barr virus recombinant from an infected Burkitt lymphoma cell line: a method useful for analysis of genes essential for transformation. Journal of Virology. 67: 606-609. DOI: 10.1128/Jvi.67.1.606-609.1993 |
0.473 |
|
1992 |
Longnecker R, Miller CL, Miao XQ, Marchini A, Kieff E. The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential. Journal of Virology. 66: 6461-9. PMID 1328675 DOI: 10.1128/Jvi.66.11.6461-6469.1992 |
0.515 |
|
1992 |
Burkhardt AL, Bolen JB, Kieff E, Longnecker R. An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases. Journal of Virology. 66: 5161-5167. PMID 1321296 DOI: 10.1128/Jvi.66.8.5161-5167.1992 |
0.468 |
|
1992 |
Marchini A, Longnecker R, Kieff E. Epstein-Barr virus (EBV)-negative B-lymphoma cell lines for clonal isolation and replication of EBV recombinants. Journal of Virology. 66: 4972-4981. PMID 1321281 DOI: 10.1128/Jvi.66.8.4972-4981.1992 |
0.544 |
|
1991 |
Longnecker R, Druker B, Roberts TM, Kieff E. An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase. Journal of Virology. 65: 3681-92. PMID 1710288 DOI: 10.1128/Jvi.65.7.3681-3692.1991 |
0.535 |
|
1991 |
Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, Longnecker R, Kieff E, Rickinson A. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell. 65: 1107-1115. PMID 1648447 DOI: 10.1016/0092-8674(91)90007-L |
0.582 |
|
1990 |
Adams AE, Johnson DI, Longnecker RM, Sloat BF, Pringle JR. CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. The Journal of Cell Biology. 111: 131-42. PMID 2195038 DOI: 10.1083/Jcb.111.1.131 |
0.359 |
|
1990 |
Longnecker R, Kieff E. A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1. Journal of Virology. 64: 2319-2326. PMID 2157888 DOI: 10.1128/Jvi.64.5.2319-2326.1990 |
0.466 |
|
1988 |
Meignier B, Longnecker R, Roizman B. In vivo behavior of genetically engineered herpes simplex viruses R7017 and R7020: construction and evaluation in rodents. The Journal of Infectious Diseases. 158: 602-14. PMID 2842408 DOI: 10.1093/Infdis/158.3.602 |
0.347 |
|
1988 |
Meignier B, Longnecker R, Mavromara-Nazos P, Sears AE, Roizman B. Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1. Virology. 162: 251-4. PMID 2827384 DOI: 10.1016/0042-6822(88)90417-5 |
0.407 |
|
1987 |
Purves FC, Longnecker RM, Leader DP, Roizman B. Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture. Journal of Virology. 61: 2896-901. PMID 3039176 DOI: 10.1128/Jvi.61.9.2896-2901.1987 |
0.488 |
|
1987 |
Longnecker R, Chatterjee S, Whitley RJ, Roizman B. Identification of a herpes simplex virus 1 glycoprotein gene within a gene cluster dispensable for growth in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 4303-7. PMID 3035578 DOI: 10.1073/Pnas.84.12.4303 |
0.408 |
|
1987 |
Longnecker R, Roizman B. Clustering of genes dispensable for growth in culture in the S component of the HSV-1 genome Science. 236: 573-576. PMID 3033823 DOI: 10.1126/Science.3033823 |
0.308 |
|
1986 |
Longnecker R, Roizman B. Generation of an inverting herpes simplex virus 1 mutant lacking the L-S junction a sequences, an origin of DNA synthesis, and several genes including those specifying glycoprotein E and the alpha 47 gene. Journal of Virology. 58: 583-591. PMID 3009870 DOI: 10.1128/Jvi.58.2.583-591.1986 |
0.318 |
|
1986 |
Ackermann M, Longnecker R, Roizman B, Pereira L. Identification, properties, and gene location of a novel glycoprotein specified by herpes simplex virus 1. Virology. 150: 207-220. PMID 3006335 DOI: 10.1016/0042-6822(86)90280-1 |
0.386 |
|
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