Year |
Citation |
Score |
2023 |
Zhang W, Sun Y, Yang Y, Chen Y. Impaired intracellular calcium homeostasis enhances protein O-GlcNAcylation and promotes vascular calcification and stiffness in diabetes. Redox Biology. 63: 102720. PMID 37230005 DOI: 10.1016/j.redox.2023.102720 |
0.343 |
|
2023 |
Giri S, Suo C, Pardi R, Fishbein GA, Rezvani K, Chen Y, Wang X. COP9 Signalosome Promotes Neointimal Hyperplasia via Deneddylation and CSN5-Mediated Nuclear Export. Biorxiv : the Preprint Server For Biology. PMID 37090553 DOI: 10.1101/2023.04.11.536468 |
0.33 |
|
2022 |
Ying KE, Feng W, Ying WZ, Li X, Xing D, Sun Y, Chen Y, Sanders PW. Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4. Redox Biology. 52: 102296. PMID 35378363 DOI: 10.1016/j.redox.2022.102296 |
0.358 |
|
2020 |
Chen Y, Zhao X, Wu H. Transcriptional Programming in Arteriosclerotic Disease: A Multifaceted Function of the Runx2 (Runt-Related Transcription Factor 2). Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120313791. PMID 33115268 DOI: 10.1161/ATVBAHA.120.313791 |
0.359 |
|
2020 |
Chen Y, Zhao X, Wu H. Arterial Stiffness: A Focus on Vascular Calcification and Its Link to Bone Mineralization. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120313131. PMID 32237904 DOI: 10.1161/Atvbaha.120.313131 |
0.455 |
|
2020 |
Li Z, Zhao Z, Cai Z, Sun Y, Li L, Yao F, Yang L, Zhou Y, Zhu H, Fu Y, Wang L, Fang W, Chen Y, Kong W. Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119314113. PMID 32212850 DOI: 10.1161/Atvbaha.119.314113 |
0.356 |
|
2020 |
Yang SZ, Xu F, Yuan K, Sun Y, Zhou T, Zhao X, McDonald JM, Chen Y. Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31896813 DOI: 10.1038/S41374-019-0365-Z |
0.368 |
|
2020 |
Zhang W, Sun Y, Yang Y, Chen Y. Enhanced Vascular Calcification and Stiffness in Diabetic Mice with SMC‐specific STIM1 deficiency The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04443 |
0.337 |
|
2019 |
Xu F, Sun Y, Yang SZ, Zhou T, Jhala N, McDonald J, Chen Y. Cytoplasmic PARP-1 Promotes Pancreatic Cancer Tumorigenesis and Resistance. International Journal of Cancer. PMID 30614530 DOI: 10.1002/Ijc.32108 |
0.384 |
|
2018 |
Yang Y, Sun Y, Chen J, Bradley WE, Dell'Italia LJ, Wu H, Chen Y. AKT-independent activation of p38 MAP kinase promotes vascular calcification. Redox Biology. 16: 97-103. PMID 29495001 DOI: 10.1016/J.Redox.2018.02.009 |
0.458 |
|
2017 |
Sun Y, Byon CH, Yang Y, Bradley WE, Dell'Italia LJ, Sanders PW, Agarwal A, Wu H, Chen Y. Dietary potassium regulates vascular calcification and arterial stiffness. Jci Insight. 2. PMID 28978809 DOI: 10.1172/Jci.Insight.94920 |
0.421 |
|
2017 |
Yang SZ, Xu F, Zhou T, Zhao X, McDonald JM, Chen Y. The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis inducing ligand. The Journal of Biological Chemistry. PMID 28476883 DOI: 10.1074/Jbc.M117.786830 |
0.376 |
|
2016 |
Agamasu C, Ghanam RH, Xu F, Sun Y, Chen Y, Saad JS. The Interplay Between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt. The Journal of Biological Chemistry. PMID 27872186 DOI: 10.1074/Jbc.M116.752816 |
0.308 |
|
2016 |
Byon CH, Heath JM, Chen Y. Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cells. Redox Biology. 9: 244-253. PMID 27591403 DOI: 10.1016/J.Redox.2016.08.015 |
0.663 |
|
2016 |
Tran NT, Su H, Khodadadi-Jamayran A, Lin S, Zhang L, Zhou D, Pawlik KM, Townes TM, Chen Y, Mulloy JC, Zhao X. The AS-RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation. Embo Reports. PMID 27118388 DOI: 10.15252/Embr.201541970 |
0.305 |
|
2016 |
Tzou YM, Bailey SK, Yuan K, Shin R, Zhang W, Chen Y, Singh RK, Shevde LA, Rama Krishna N. Identification of initial leads directed at the calmodulin-binding region on the Src-SH2 domain that exhibit anti-proliferation activity against pancreatic cancer. Bioorganic & Medicinal Chemistry Letters. PMID 26803204 DOI: 10.1016/J.Bmcl.2016.01.027 |
0.351 |
|
2016 |
Ma L, Ambalavanan N, Liu H, Sun Y, Jhala N, Bradley WE, Dell'Italia LJ, Michalek S, Wu H, Steele C, Benza RL, Chen Y. TLR4 regulates pulmonary vascular homeostasis and remodeling via redox signaling. Frontiers in Bioscience (Landmark Edition). 21: 397-409. PMID 26709781 DOI: 10.2741/4396 |
0.378 |
|
2015 |
Yuan K, Yong S, Xu F, Zhou T, McDonald JM, Chen Y. Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer. Oncotarget. PMID 26320171 DOI: 10.18632/Oncotarget.4490 |
0.399 |
|
2015 |
Byon CH, Chen Y. Molecular Mechanisms of Vascular Calcification in Chronic Kidney Disease: The Link between Bone and the Vasculature. Current Osteoporosis Reports. 13: 206-15. PMID 25947259 DOI: 10.1007/S11914-015-0270-3 |
0.371 |
|
2015 |
Deng L, Huang L, Sun Y, Heath JM, Wu H, Chen Y. Inhibition of FOXO1/3 promotes vascular calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 175-83. PMID 25378413 DOI: 10.1161/Atvbaha.114.304786 |
0.689 |
|
2014 |
Heath JM, Sun Y, Yuan K, Bradley WE, Litovsky S, Dell'Italia LJ, Chatham JC, Wu H, Chen Y. Activation of AKT by O-linked N-acetylglucosamine induces vascular calcification in diabetes mellitus. Circulation Research. 114: 1094-102. PMID 24526702 DOI: 10.1161/Circresaha.114.302968 |
0.659 |
|
2014 |
Yuan K, Zhou T, McDonald J, Chen Y. Abstract 2268: Augmentation of DR5 expression by calmodulin antagonists sensitizes TRA-8-induced apoptosis in pancreatic cancer Cancer Research. 74: 2268-2268. DOI: 10.1158/1538-7445.Am2014-2268 |
0.403 |
|
2013 |
Yuan K, Sun Y, Zhou T, McDonald J, Chen Y. PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4750-9. PMID 23833311 DOI: 10.1158/1078-0432.Ccr-13-0516 |
0.307 |
|
2013 |
Fernandez TF, Samal AB, Bedwell GJ, Chen Y, Saad JS. Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin. The Journal of Biological Chemistry. 288: 21898-908. PMID 23760276 DOI: 10.1074/Jbc.M113.471821 |
0.37 |
|
2013 |
Yuan K, Zhou T, McDonald J, Chen Y. Abstract 2953: Inhibition of calmodulin enhances TRA-8-induced apoptosis in pancreatic cancer cells . Cancer Research. 73: 2953-2953. DOI: 10.1158/1538-7445.Am2013-2953 |
0.415 |
|
2013 |
Yuan K, Sun Y, Zhou T, McDonald J, Chen Y. Abstract 2947: PARP-1 regulates death receptor 5-mediated apoptosis in pancreatic cancer. Cancer Research. 73: 2947-2947. DOI: 10.1158/1538-7445.Am2013-2947 |
0.398 |
|
2012 |
Sun Y, Byon CH, Yuan K, Chen J, Mao X, Heath JM, Javed A, Zhang K, Anderson PG, Chen Y. Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. Circulation Research. 111: 543-52. PMID 22773442 DOI: 10.1161/Circresaha.112.267237 |
0.693 |
|
2012 |
Mao X, Debenedittis P, Sun Y, Chen J, Yuan K, Jiao K, Chen Y. Vascular smooth muscle cell Smad4 gene is important for mouse vascular development. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2171-7. PMID 22772757 DOI: 10.1161/Atvbaha.112.253872 |
0.415 |
|
2012 |
Chen J, Yuan K, Mao X, Miano JM, Wu H, Chen Y. Serum response factor regulates bone formation via IGF-1 and Runx2 signals. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1659-68. PMID 22434656 DOI: 10.1002/Jbmr.1607 |
0.379 |
|
2012 |
Jing G, Yuan K, Liang Q, Sun Y, Mao X, McDonald JM, Chen Y. Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 82-90. PMID 21912376 DOI: 10.1038/Labinvest.2011.131 |
0.329 |
|
2012 |
Yuan K, Zhou T, McDonald J, Chen Y. Abstract 246: Calmodulin binding to death receptor-5 regulates pancreatic cancer apoptosis Cancer Research. 72: 246-246. DOI: 10.1158/1538-7445.Am2012-246 |
0.417 |
|
2011 |
Pan D, Yan Q, Chen Y, McDonald JM, Song Y. Trifluoperazine regulation of calmodulin binding to Fas: a computational study. Proteins. 79: 2543-56. PMID 21656570 DOI: 10.1002/Prot.23081 |
0.328 |
|
2011 |
Yuan K, Jing G, Chen J, Liu H, Zhang K, Li Y, Wu H, McDonald JM, Chen Y. Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK). The Journal of Biological Chemistry. 286: 24776-84. PMID 21613217 DOI: 10.1074/Jbc.M110.202804 |
0.424 |
|
2011 |
Jing G, Yuan K, Turk AN, Jhala NC, Arnoletti JP, Zhang K, McDonald JM, Chen Y. Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 896-904. PMID 21464824 DOI: 10.1038/Labinvest.2011.60 |
0.408 |
|
2011 |
Byon CH, Sun Y, Chen J, Yuan K, Mao X, Heath JM, Anderson PG, Tintut Y, Demer LL, Wang D, Chen Y. Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1387-96. PMID 21454810 DOI: 10.1161/Atvbaha.110.222547 |
0.699 |
|
2011 |
Ma L, Chang J, Wu H, Chen Y. Hypoxia-Induced Pulmonary Arterial Hypertension: The Role of TLR4 Blood. 118: 1146-1146. DOI: 10.1182/Blood.V118.21.1146.1146 |
0.354 |
|
2011 |
Yuan K, Jing G, Chen J, Chen Y. Abstract 4776: Calmodulin modulates Fas-induced survival signals in pancreatic cancer cells Cancer Research. 71: 4776-4776. DOI: 10.1158/1538-7445.Am2011-4776 |
0.418 |
|
2011 |
Jing G, Yuan K, Turk AN, McDonald JM, Chen Y. Abstract 4089: Calmodulin antagonists inhibit cholangiocarcinoma tumorigenesis independent of gemcitabine by the activating of caspase 2 Cancer Research. 71: 4089-4089. DOI: 10.1158/1538-7445.Am2011-4089 |
0.405 |
|
2010 |
Chen J, Sun Y, Mao X, Liu Q, Wu H, Chen Y. RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis. The Journal of Biological Chemistry. 285: 36315-21. PMID 20837480 DOI: 10.1074/Jbc.M110.157743 |
0.399 |
|
2010 |
Pan D, Yan Q, Chen Y, McDonald JM, Song Y. Abstract 96: Conformational and thermodynamics analyses of the regulation of trifluoperazine on camodulin binding to Fas: Implications for cancer chemotherapy Cancer Research. 70: 96-96. DOI: 10.1158/1538-7445.Am10-96 |
0.347 |
|
2010 |
Jing G, Turk AN, Sun Y, Pawar P, Chen Y, McDonald JM. Abstract 126: Gemcitabine enhances therapeutic effect of tamoxifen on cholangiocarcinoma Cancer Research. 70: 126-126. DOI: 10.1158/1538-7445.Am10-126 |
0.391 |
|
2009 |
Byon CH, Hardy RW, Ren C, Ponnazhagan S, Welch DR, McDonald JM, Chen Y. Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 1221-8. PMID 19752858 DOI: 10.1038/Labinvest.2009.97 |
0.326 |
|
2009 |
Pawar P, Ma L, Byon CH, Liu H, Ahn EY, Jhala N, Arnoletti JP, McDonald JM, Chen Y. Molecular mechanisms of tamoxifen therapy for cholangiocarcinoma: role of calmodulin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1288-96. PMID 19228732 DOI: 10.1158/1078-0432.Ccr-08-1150 |
0.417 |
|
2008 |
Schneider DJ, Chen Y, Sobel BE. The effect of plasminogen activator inhibitor type 1 on apoptosis. Thrombosis and Haemostasis. 100: 1037-40. PMID 19132227 DOI: 10.1160/Th08-04-0234 |
0.404 |
|
2008 |
Suever JD, Chen Y, McDonald JM, Song Y. Conformation and free energy analyses of the complex of calcium-bound calmodulin and the Fas death domain. Biophysical Journal. 95: 5913-21. PMID 18820240 DOI: 10.1529/Biophysj.108.130542 |
0.314 |
|
2008 |
Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, Liu J, Feng X, McDonald JM, Michalek S, He Y, Yu M, Fu YX, Wen R, Wu H, et al. Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis. The Journal of Biological Chemistry. 283: 29593-601. PMID 18728019 DOI: 10.1074/Jbc.M802493200 |
0.316 |
|
2008 |
Byon CH, Javed A, Dai Q, Kappes JC, Clemens TL, Darley-Usmar VM, McDonald JM, Chen Y. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. The Journal of Biological Chemistry. 283: 15319-27. PMID 18378684 DOI: 10.1074/Jbc.M800021200 |
0.445 |
|
2008 |
Pawar PS, Micoli KJ, Ding H, Cook WJ, Kappes JC, Chen Y, McDonald JM. Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling. The Biochemical Journal. 412: 459-68. PMID 18257744 DOI: 10.1042/Bj20071507 |
0.394 |
|
2008 |
Chen Y, Pawar P, Pan G, Ma L, Liu H, McDonald JM. Calmodulin binding to the Fas-mediated death-inducing signaling complex in cholangiocarcinoma cells. Journal of Cellular Biochemistry. 103: 788-99. PMID 17654480 DOI: 10.1002/Jcb.21447 |
0.417 |
|
2007 |
Pan G, Ahn EY, Chen Y, Feng G, Reddy V, Jhala NC, McDonald JM. Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma. International Journal of Oncology. 31: 843-50. PMID 17786316 DOI: 10.3892/Ijo.31.4.843 |
0.386 |
|
2006 |
Chen Y, Xu J, Jhala N, Pawar P, Zhu ZB, Ma L, Byon CH, McDonald JM. Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein. The American Journal of Pathology. 169: 1833-42. PMID 17071604 DOI: 10.2353/Ajpath.2006.060234 |
0.434 |
|
2006 |
Chen Y, Budd RC, Kelm RJ, Sobel BE, Schneider DJ. Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1777-83. PMID 16709941 DOI: 10.1161/01.Atv.0000227514.50065.2A |
0.434 |
|
2006 |
Chen Y, Schneider D, Sobel B. Increased expression of plasminogen activator inhibitor type 1 promotes proliferation of vascular smooth muscle cells Journal of Molecular and Cellular Cardiology. 40: 1010. DOI: 10.1016/J.Yjmcc.2006.03.261 |
0.423 |
|
2004 |
Chen Y, Kelm RJ, Budd RC, Sobel BE, Schneider DJ. Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1. Journal of Cellular Biochemistry. 92: 178-88. PMID 15095413 DOI: 10.1002/Jcb.20058 |
0.442 |
|
2003 |
Nordt TK, Ernst S, Chen Y, Schneider DJ, Bode C, Sobel BE. Genotype-dependent inhibition of PAl-1 expression in human vascular smooth muscle cells by PPAR-Gamma agonists Journal of the American College of Cardiology. 41: 248. DOI: 10.1016/S0735-1097(03)81739-4 |
0.384 |
|
2002 |
Chen Y, Schneider DJ. The independence of signaling pathways mediating increased expression of plasminogen activator inhibitor type 1 in HepG2 cells exposed to free fatty acids or triglycerides. International Journal of Experimental Diabetes Research. 3: 109-18. PMID 11991197 DOI: 10.1080/15604280214488 |
0.328 |
|
2001 |
Chen Y, Billadello JJ, Schneider DJ. Identification and localization of a fatty acid response region in the human plasminogen activator inhibitor-1 gene. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2696-701. PMID 11116074 DOI: 10.1161/01.Atv.20.12.2696 |
0.347 |
|
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