Amber M. Hohl, Ph.D. - Related publications

2012 Biochemistry University of Iowa, Iowa City, IA 
Genetics, Cell Biology, Oncology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Dougherty AC, Hawaz MG, Hoang KG, Trac J, Keck JM, Ayes C, Deweese JE. Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity. Acs Omega. 6: 25892-25903. PMID 34660952 DOI: 10.1021/acsomega.1c02083   
2021 Padmanabhan S, Sanyal K, Dubey D. Identification and analysis of the origin recognition complex in the human fungal pathogen . Micropublication Biology. 2021. PMID 34568775 DOI: 10.17912/micropub.biology.000465   
2021 Bonilla B, Brown AI, Hengel SR, Rapchak KS, Mitchell D, Pressimone CA, Fagunloye AA, Luong TT, Russell RA, Vyas RK, Mertz TM, Zaher HS, Mosammaparast N, Malc EP, Mieczkowski PA, et al. The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. Elife. 10. PMID 34723799 DOI: 10.7554/eLife.68080   
2021 Ali S, Zhang T, Lambing C, Wang W, Zhang P, Xie L, Wang J, Khan N, Zhang Q. Loss of chromatin remodeler DDM1 causes segregation distortion in Arabidopsis thaliana. Planta. 254: 107. PMID 34694462 DOI: 10.1007/s00425-021-03763-5   
2021 Singh JK, Smith R, Rother MB, de Groot AJL, Wiegant WW, Vreeken K, D'Augustin O, Kim RQ, Qian H, Krawczyk PM, González-Prieto R, Vertegaal ACO, Lamers M, Huet S, van Attikum H. Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining. Nature Communications. 12: 6560. PMID 34772923 DOI: 10.1038/s41467-021-26691-0   
2021 Gómez-González B, Ortega P, Aguilera A. Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast. Methods in Enzymology. 661: 121-138. PMID 34776209 DOI: 10.1016/bs.mie.2021.08.010   
2021 Llorens-Agost M, Ensminger M, Le HP, Gawai A, Liu J, Cruz-García A, Bhetawal S, Wood RD, Heyer WD, Löbrich M. POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis. Nature Cell Biology. 23: 1095-1104. PMID 34616022 DOI: 10.1038/s41556-021-00764-0   
2021 Day M, Oliver AW, Pearl LH. Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. Dna Repair. 108: 103232. PMID 34678589 DOI: 10.1016/j.dnarep.2021.103232   
2021 Nitiss JL, Kiianitsa K, Sun Y, Nitiss KC, Maizels N. Topoisomerase Assays. Current Protocols. 1: e250. PMID 34606690 DOI: 10.1002/cpz1.250   
2021 Joshi R, Banerjee SJ, Curtiss J, Ashley AK. DNA ligase IV mutations confer shorter lifespan and increased sensitivity to nutrient stress in Drosophila melanogaster. Journal of Applied Genetics. PMID 34817771 DOI: 10.1007/s13353-021-00637-0   
2021 Cantor SB. Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer". Dna Repair. 107: 103209. PMID 34419699 DOI: 10.1016/j.dnarep.2021.103209   
2021 Sarkar R, Petrushenko ZM, Dawson DS, Rybenkov VV. Ycs4 Subunit of Condensin Binds DNA and Modulates the Enzyme Turnover. Biochemistry. PMID 34723504 DOI: 10.1021/acs.biochem.1c00473   
2021 Heath J, Cheyou ES, Findlay S, Luo VM, Carpio EP, Lee J, Djerir B, Chen X, Morin T, Lebeau B, Karam M, Bagci H, Grapton D, Ursini-Siegel J, Côté JF, et al. POGZ promotes homology-directed DNA repair in an HP1-dependent manner. Embo Reports. e51041. PMID 34758190 DOI: 10.15252/embr.202051041   
2021 Chen Y, Li Y, Xiong J, Lan B, Wang X, Liu J, Lin J, Fei Z, Zheng X, Chen C. Role of PRKDC in cancer initiation, progression, and treatment. Cancer Cell International. 21: 563. PMID 34702253 DOI: 10.1186/s12935-021-02229-8   
2021 Zhang J, Nandakumar J, Shibuya H. BRCA2 in mammalian meiosis. Trends in Cell Biology. PMID 34625364 DOI: 10.1016/j.tcb.2021.09.003   
2021 Swan RL, Cowell IG, Austin CA. . Molecular Pharmacology. PMID 34689119 DOI: 10.1124/molpharm.121.000374   
2021 Leavitt JC, Gilcrease EB, Woodbury BM, Teschke CM, Casjens SR. Intravirion DNA Can Access the Space Occupied by the Bacteriophage P22 Ejection Proteins. Viruses. 13. PMID 34452369 DOI: 10.3390/v13081504   
2021 Bailey CG, Gupta S, Metierre C, Amarasekera PMS, O'Young P, Kyaw W, Laletin T, Francis H, Semaan C, Sharifi Tabar M, Singh KP, Mullighan CG, Wolkenhauer O, Schmitz U, Rasko JEJ. Structure-function relationships explain CTCF zinc finger mutation phenotypes in cancer. Cellular and Molecular Life Sciences : Cmls. PMID 34657170 DOI: 10.1007/s00018-021-03946-z   
2021 Cappadocia L, Kochańczyk T, Lima CD. DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA. The Embo Journal. e103787. PMID 34585421 DOI: 10.15252/embj.2019103787   
2021 Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo TE, Ferguson B, Naqi A, Walker GJ, Bolderson E, Gamsjaeger R, O'Byrne KJ, Cubeddu L, Khanna KK, Richard DJ. hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage. Scientific Reports. 11: 20256. PMID 34642383 DOI: 10.1038/s41598-021-99355-0   
2021 Meier B, Volkova NV, Wang B, González-Huici V, Bertolini S, Campbell PJ, Gerstung M, Gartner A. C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation. Plos One. 16: e0258269. PMID 34614038 DOI: 10.1371/journal.pone.0258269   
2021 Zhang X, Zheng Q. How DNA affects the hyperthermophilic protein Ape10b2 for oligomerization: an investigation using multiple short molecular dynamics simulations. Physical Chemistry Chemical Physics : Pccp. 23: 25841-25849. PMID 34763347 DOI: 10.1039/d1cp04341b   
2021 Chatterjee C, Majumdar S, Deshpande S, Pant D, Matheshwaran S. Real-time kinetic studies of Mycobacterium tuberculosis LexA-DNA interaction. Bioscience Reports. 41. PMID 34792534 DOI: 10.1042/BSR20211419   
2021 Sekurova ON, Sun YQ, Zehl M, Rückert C, Stich A, Busche T, Kalinowski J, Zotchev SB. Coupling of the engineered DNA "mutator" to a biosensor as a new paradigm for activation of silent biosynthetic gene clusters in Streptomyces. Nucleic Acids Research. 49: 8396-8405. PMID 34197612 DOI: 10.1093/nar/gkab583   
2021 Pan J, Lian K, Sarre A, Leiros HS, Williamson A. Bacteriophage origin of some minimal ATP-dependent DNA ligases: a new structure from Burkholderia pseudomallei with striking similarity to Chlorella virus ligase. Scientific Reports. 11: 18693. PMID 34548548 DOI: 10.1038/s41598-021-98155-w   
2021 Sánchez-Osuna M, Cortés P, Lee M, Smith AT, Barbé J, Erill I. Non-canonical LexA proteins regulate the SOS response in the Bacteroidetes. Nucleic Acids Research. PMID 34614190 DOI: 10.1093/nar/gkab773   
2021 Ma J, Shi Q, Cui G, Sheng H, Botuyan MV, Zhou Y, Yan Y, He Y, Wang L, Wang Y, Mer G, Ye D, Wang C, Huang H. SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition. Nature Communications. 12: 5779. PMID 34599168 DOI: 10.1038/s41467-021-26049-6   
2021 Sanchez-Bailon MP, Choi SY, Dufficy ER, Sharma K, McNee GS, Gunnell E, Chiang K, Sahay D, Maslen S, Stewart GS, Skehel JM, Dreveny I, Davies CC. Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair. Nature Communications. 12: 6313. PMID 34728620 DOI: 10.1038/s41467-021-26413-6   
2021 Austin CA, Cowell IG, Khazeem MM, Lok D, Ng HT. TOP2B's contributions to transcription. Biochemical Society Transactions. PMID 34747992 DOI: 10.1042/BST20200454   
2021 Mishra S, Jeon J, Kang JK, Song SH, Kim TY, Ban C, Choi H, Kim Y, Kim M, Park JW. Direct Detection of Low Abundance Genes of Single Point Mutation. Nano Letters. PMID 34672610 DOI: 10.1021/acs.nanolett.1c02728   
2021 Liang W, Li J, Sun L, Liu Y, Lan Z, Qian W. Deciphering the synergistic and redundant roles of CG and non-CG DNA methylation in plant development and transposable element silencing. The New Phytologist. PMID 34655488 DOI: 10.1111/nph.17804   
2021 Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Roman HL, Posada LM, Gunaratne C, Li J, Dupere-Richer D, et al. DNMT3A harboring leukemia-associated mutations directs sensitivity to DNA damage at replication forks. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34716195 DOI: 10.1158/1078-0432.CCR-21-2863   
2021 Li J, Liang W, Liu Y, Ren Z, Ci D, Chang J, Qian W. The Arabidopsis ATR-SOG1 signaling module regulates pleiotropic developmental adjustments in response to 3'-blocked DNA repair intermediates. The Plant Cell. PMID 34791445 DOI: 10.1093/plcell/koab282   
2021 Lin Y, Zhang X, Wang Y, Zhang J, Liu Q. Single-stranded DNA generated by high temperature accepts protons and builds up mutagenic and carcinogenic strong acids. Molecular Biology Reports. PMID 34643928 DOI: 10.1007/s11033-021-06804-0   
2021 Gabriel P, Maranha FG, Nordlander E, Neves A, Terenzi H. A heterotrinuclear bioinspired coordination complex capable of binding to DNA and emulation of nuclease activity. Journal of Inorganic Biochemistry. 226: 111631. PMID 34717251 DOI: 10.1016/j.jinorgbio.2021.111631   
2021 Liu J, Mei Q, Nimer S, Fitzgerald DM, Rosenberg SM. Genomic mapping of DNA-repair reaction intermediates in living cells with engineered DNA structure-trap proteins. Methods in Enzymology. 661: 155-181. PMID 34776211 DOI: 10.1016/bs.mie.2021.09.015   
2021 Park SH, Kim Y, Ra JS, Wie MW, Kang MS, Kang S, Myung K, Lee KY. Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair. Nucleic Acids Research. PMID 34718749 DOI: 10.1093/nar/gkab999   
2021 Thakur BL, Ray A, Redon CE, Aladjem MI. Preventing excess replication origin activation to ensure genome stability. Trends in Genetics : Tig. PMID 34625299 DOI: 10.1016/j.tig.2021.09.008   
2021 Clay DE, Bretscher HS, Jezuit EA, Bush KB, Fox DT. Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation. The Journal of Cell Biology. 220. PMID 34613334 DOI: 10.1083/jcb.202106116   
2021 Kumar R, Bahng S, Marians KJ. The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities. Nucleic Acids Research. PMID 34747485 DOI: 10.1093/nar/gkab1027   
2021 Sugiyama T, Keinard B, Best G, Sanyal MR. Biochemical and photochemical mechanisms that produce different UV-induced mutation spectra. Mutation Research. 823: 111762. PMID 34563793 DOI: 10.1016/j.mrfmmm.2021.111762   
2021 Jay A, Reitz D, Namekawa SH, Heyer WD. Cancer testis antigens and genomic instability: More than immunology. Dna Repair. 108: 103214. PMID 34481156 DOI: 10.1016/j.dnarep.2021.103214   
2021 Guo Y, Rall-Scharpf M, Bourdon JC, Wiesmüller L, Biber S. p53 isoforms differentially impact on the POLι dependent DNA damage tolerance pathway. Cell Death & Disease. 12: 941. PMID 34645785 DOI: 10.1038/s41419-021-04224-3   
2021 Xue C, Wang L, Huang H, Wang R, Yuan P, Wu ZS. Stimuli-Induced Upgrade of Nuclease-Resistant DNA Nanostructure Composed of a Single Molecular Beacon for Detecting Mutant Genes. Acs Sensors. PMID 34731570 DOI: 10.1021/acssensors.1c01423   
2021 Park SH, Kim SJ, Myung K, Lee KY. Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism. Scientific Reports. 11: 21817. PMID 34751190 DOI: 10.1038/s41598-021-01336-w   
2021 Bürmann F, Funke LFH, Chin JW, Löwe J. Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Molecular Cell. PMID 34739874 DOI: 10.1016/j.molcel.2021.10.011   
2021 Sobrino-Reig E, Meizoso T, García J, Varillas-Delgado D, Martin YB. Morphological predictors for microsatellite instability in urothelial carcinoma. Diagnostic Pathology. 16: 106. PMID 34801034 DOI: 10.1186/s13000-021-01168-2   
2021 James RC, Bellani MA, Zhang J, Huang J, Shaik A, Pokharel D, Gali H, Gichimu J, Thazhathveetil AK, Seidman MM. Visualizing replication fork encounters with DNA interstrand crosslinks. Methods in Enzymology. 661: 53-75. PMID 34776223 DOI: 10.1016/bs.mie.2021.08.015   
2021 Okafor IC, Choi J, Ha T. Single Molecule Methods for studying CRISPR Cas9-Induced DNA Unwinding. Methods (San Diego, Calif.). PMID 34767923 DOI: 10.1016/j.ymeth.2021.11.003   
2021 Berger MB, Walker AR, Vázquez-Montelongo EA, Cisneros GA. Computational investigations of selected enzymes from two iron and α-ketoglutarate-dependent families. Physical Chemistry Chemical Physics : Pccp. 23: 22227-22240. PMID 34586107 DOI: 10.1039/d1cp03800a