Year |
Citation |
Score |
2024 |
Arai S, Gao Y, Yu Z, Xie L, Wang L, Zhang T, Nouri M, Chen S, Asara JM, Balk SP. A carboxy-terminal ubiquitylation site regulates androgen receptor activity. Communications Biology. 7: 25. PMID 38182874 DOI: 10.1038/s42003-023-05709-x |
0.367 |
|
2023 |
Guo J, Wei Z, Jia T, Wang L, Nama N, Liang J, Liao X, Liu X, Gao Y, Liu X, Wang K, Fu B, Chen SS. Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions. Journal of Translational Medicine. 21: 716. PMID 37828515 DOI: 10.1186/s12967-023-04429-4 |
0.602 |
|
2023 |
Fu B, Wang L, Jia T, Wei Z, Nama N, Liang J, Liao X, Liu X, Gao Y, Liu X, Mao RS, Wang K, Guo J, Chen SS. Androgen receptor and MYC transcriptomes are equilibrated in multilayer regulatory circuitries in prostate cancer. The Prostate. PMID 37565264 DOI: 10.1002/pros.24603 |
0.544 |
|
2023 |
Wei Z, Wang S, Xu Y, Wang W, Soares F, Ahmed M, Su P, Wang T, Orouji E, Xu X, Zeng Y, Chen S, Liu X, Jia T, Liu Z, ... Chen S, et al. MYC reshapes CTCF-mediated chromatin architecture in prostate cancer. Nature Communications. 14: 1787. PMID 36997534 DOI: 10.1038/s41467-023-37544-3 |
0.507 |
|
2022 |
Zhang H, Zhang L, Chen S, Yao M, Ma Z, Yuan Y. Yeast-based evolutionary modeling of androgen receptor mutations and natural selection. Plos Genetics. 18: e1010518. PMID 36459502 DOI: 10.1371/journal.pgen.1010518 |
0.372 |
|
2022 |
Zhang H, Zhang L, Xu Y, Chen S, Ma Z, Yao M, Li F, Li B, Yuan Y. Simulating androgen receptor selection in designer yeast. Synthetic and Systems Biotechnology. 7: 1108-1116. PMID 36017332 DOI: 10.1016/j.synbio.2022.07.005 |
0.44 |
|
2021 |
Guo H, Wu Y, Nouri M, Spisak S, Russo JW, Sowalsky AG, Pomerantz MM, Wei Z, Korthauer K, Seo JH, Wang L, Arai S, Freedman ML, He HH, Chen S, et al. Androgen receptor and MYC equilibration centralizes on developmental super-enhancer. Nature Communications. 12: 7308. PMID 34911936 DOI: 10.1038/s41467-021-27077-y |
0.584 |
|
2021 |
Liang J, Wang L, Poluben L, Nouri M, Arai S, Xie L, Voznesensky OS, Cato L, Yuan X, Russo JW, Long HW, Brown M, Chen S, Balk SP. Androgen receptor splice variant 7 functions independently of the full length receptor in prostate cancer cells. Cancer Letters. PMID 34256096 DOI: 10.1016/j.canlet.2021.07.013 |
0.585 |
|
2021 |
Gao X, Liang J, Wang L, Zhang Z, Yuan P, Wang J, Gao Y, Ma F, Calagua C, Ye H, Voznesensky O, Wang S, Wang T, Liu J, Chen S, et al. Phosphorylation of the Androgen Receptor at Ser81 is co-sustained by CDK1 and CDK9 and leads to AR-mediated transactivation in prostate cancer. Molecular Oncology. PMID 33932081 DOI: 10.1002/1878-0261.12968 |
0.557 |
|
2020 |
Canesin G, Di Ruscio A, Li M, Ummarino S, Hedblom A, Choudhury R, Krzyzanowska A, Csizmadia E, Palominos M, Stiehm A, Ebralidze A, Chen SY, Bassal MA, Zhao P, Tolosano E, et al. Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases. Cell Reports. 32: 108181. PMID 32966797 DOI: 10.1016/j.celrep.2020.108181 |
0.398 |
|
2018 |
Tinzl M, Chen B, Chen SY, Semenas J, Abrahamsson PA, Dizeyi N. Correction: Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer. Plos One. 13: e0209544. PMID 30562402 DOI: 10.1371/journal.pone.0209544 |
0.442 |
|
2018 |
Russo JW, Liu X, Ye H, Calagua C, Chen S, Voznesensky O, Condulis J, Ma F, Taplin ME, Einstein DJ, Balk SP, Chen S. Phosphorylation of Androgen Receptor Serine 81 is Associated with its Reactivation in Castration-Resistant Prostate Cancer. Cancer Letters. PMID 30217568 DOI: 10.1016/J.Canlet.2018.09.014 |
0.619 |
|
2017 |
Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, Zhang T, Russo J, Cai C, Yuan X, Liu J, Chen S, Balk SP. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Research. PMID 28062857 DOI: 10.1093/Nar/Gkw1291 |
0.698 |
|
2016 |
Gao S, Gao Y, He HH, Han D, Han W, Avery A, Macoska JA, Liu X, Chen S, Ma F, Chen S, Balk SP, Cai C. Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein. Cell Reports. 17: 966-976. PMID 27760327 DOI: 10.1016/J.Celrep.2016.09.064 |
0.764 |
|
2016 |
Sun R, Zhang S, Hu W, Lu X, Lou N, Yang Z, Chen S, Zhang X, Yang H. Valproic Acid Attenuates Skeletal Muscle Wasting by Inhibiting C/EBPβ-regulated Atrogin1 Expression in Cancer Cachexia. American Journal of Physiology. Cell Physiology. ajpcell.00344.2015. PMID 27122162 DOI: 10.1152/Ajpcell.00344.2015 |
0.344 |
|
2016 |
Liu X, Han W, Gulla S, Simon NI, Gao Y, Liu J, Wang L, Yang H, Zhang X, Chen S. Androgen ablation elicits PP1-dependence for AR stabilization and transactivation in prostate cancer. The Prostate. PMID 26847655 DOI: 10.1002/Pros.23157 |
0.655 |
|
2016 |
Liu X, Gao Y, Cai C, Balk S, Chen S. Abstract A13: Androgen receptor functions as an adaptor protein for recruitment of protein phosphatase 1a to chromatin and CDK9 mobilization Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-A13 |
0.703 |
|
2015 |
Liu X, Han W, Gulla S, Simon NI, Gao Y, Cai C, Yang H, Zhang X, Liu J, Balk SP, Chen S. Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation. Oncotarget. PMID 26636645 DOI: 10.18632/Oncotarget.6434 |
0.769 |
|
2015 |
Wang X, Chen X, Han W, Ruan A, Chen L, Wang R, Xu Z, Xiao P, Lu X, Zhao Y, Zhou J, Chen S, Du Q, Yang H, Zhang X. miR-200c Targets CDK2 and Suppresses Tumorigenesis in Renal Cell Carcinoma. Molecular Cancer Research : McR. PMID 26248649 DOI: 10.1158/1541-7786.Mcr-15-0128 |
0.336 |
|
2015 |
Sowalsky AG, Xia Z, Wang L, Zhao H, Chen S, Bubley GJ, Balk SP, Li W. Whole transcriptome sequencing reveals extensive unspliced mRNA in metastatic castration-resistant prostate cancer. Molecular Cancer Research : McR. 13: 98-106. PMID 25189356 DOI: 10.1158/1541-7786.Mcr-14-0273 |
0.588 |
|
2015 |
Gao Y, Gao S, He H, Liu X, Chen S, Ma F, Liu XS, Brown M, Balk SP, Chen S, Cai C. Abstract 1849: Androgen receptor transcriptionally represses genes mediating DNA synthesis and repair in prostate cancer Cancer Research. 75: 1849-1849. DOI: 10.1158/1538-7445.Am2015-1849 |
0.743 |
|
2014 |
Cai C, He HH, Gao S, Chen S, Yu Z, Gao Y, Chen S, Chen MW, Zhang J, Ahmed M, Wang Y, Metzger E, Schüle R, Liu XS, Brown M, et al. Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity. Cell Reports. 9: 1618-27. PMID 25482560 DOI: 10.1016/J.Celrep.2014.11.008 |
0.683 |
|
2014 |
Hsieh CL, Fei T, Chen Y, Li T, Gao Y, Wang X, Sun T, Sweeney CJ, Lee GS, Chen S, Balk SP, Liu XS, Brown M, Kantoff PW. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7319-24. PMID 24778216 DOI: 10.1073/Pnas.1324151111 |
0.782 |
|
2014 |
Yang H, Chen X, Wang X, Li Y, Chen S, Qian X, Wang R, Chen L, Han W, Ruan A, Du Q, Olumi AF, Zhang X. Inhibition of PP2A activity confers a TRAIL-sensitive phenotype during malignant transformation. Molecular Cancer Research : McR. 12: 217-27. PMID 24296757 DOI: 10.1158/1541-7786.MCR-13-0441 |
0.311 |
|
2013 |
Gao Y, Chen S. Proline-Directed Androgen Receptor Phosphorylation. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 7: 75. PMID 25866551 DOI: 10.4172/1747-0862.1000075 |
0.339 |
|
2013 |
Tinzl M, Chen B, Chen SY, Semenas J, Abrahamsson PA, Dizeyi N. Interaction between c-jun and androgen receptor determines the outcome of taxane therapy in castration resistant prostate cancer. Plos One. 8: e79573. PMID 24260253 DOI: 10.1371/journal.pone.0079573 |
0.483 |
|
2012 |
Chen S, Gulla S, Cai C, Balk SP. Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation. The Journal of Biological Chemistry. 287: 8571-83. PMID 22275373 DOI: 10.1074/Jbc.M111.325290 |
0.698 |
|
2012 |
Sun T, Yang M, Chen S, Balk S, Pomerantz M, Hsieh CL, Brown M, Lee GS, Kantoff PW. The altered expression of MiR-221/-222 and MiR-23b/-27b is associated with the development of human castration resistant prostate cancer. The Prostate. 72: 1093-103. PMID 22127852 DOI: 10.1002/Pros.22456 |
0.6 |
|
2012 |
Tinzl M, Chen B, Chen S, Abrahamsson P, Dizeyi N. 934 Androgen receptor expression is induced by docetaxel in prostate cancer cells European Urology Supplements. 11: e934-e934a. DOI: 10.1016/S1569-9056(12)60931-2 |
0.597 |
|
2011 |
Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z, Chen S, Nelson PS, Liu XS, Brown M, Balk SP. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell. 20: 457-71. PMID 22014572 DOI: 10.1016/J.Ccr.2011.09.001 |
0.767 |
|
2011 |
Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon NI, Wang H, Chen S, Balk SP. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Research. 71: 6503-13. PMID 21868758 DOI: 10.1158/0008-5472.Can-11-0532 |
0.712 |
|
2011 |
Sun T, Yang M, Chen S, Balk S, Pomerantz M, Brown M, Kantoff PW, Lee GM. Abstract 174: MicroRNA signatures of castration resistant human prostate cancer Cancer Research. 71: 174-174. DOI: 10.1158/1538-7445.Am2011-174 |
0.385 |
|
2011 |
Tinzl M, Chen B, Fang K, Chen S, Abrahamsson P, Dizeyi N. 941 C-JUN INTERVENES WITH DOCETAXEL THERAPY IN CASTRATION-RESISTANT PROSTATE CANCER: AR STILL MATTERS European Urology Supplements. 10: 294. DOI: 10.1016/S1569-9056(11)60923-8 |
0.474 |
|
2009 |
Chen S, Kesler CT, Paschal BM, Balk SP. Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. The Journal of Biological Chemistry. 284: 25576-84. PMID 19622840 DOI: 10.1074/Jbc.M109.043133 |
0.596 |
|
2009 |
Cai C, Wang H, Xu Y, Chen S, Balk SP. Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Research. 69: 6027-32. PMID 19584279 DOI: 10.1158/0008-5472.Can-09-0395 |
0.753 |
|
2009 |
Cai C, Portnoy DC, Wang H, Jiang X, Chen S, Balk SP. Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2. Cancer Research. 69: 5202-9. PMID 19491261 DOI: 10.1158/0008-5472.Can-09-0026 |
0.752 |
|
2008 |
Hsieh CL, Cai C, Giwa A, Bivins A, Chen SY, Sabry D, Govardhan K, Shemshedini L. Expression of a hyperactive androgen receptor leads to androgen-independent growth of prostate cancer cells. Journal of Molecular Endocrinology. 41: 13-23. PMID 18469090 DOI: 10.1677/Jme-07-0158 |
0.855 |
|
2007 |
Cai C, Hsieh CL, Omwancha J, Zheng Z, Chen SY, Baert JL, Shemshedini L. ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion. Molecular Endocrinology (Baltimore, Md.). 21: 1835-46. PMID 17505060 DOI: 10.1210/Me.2006-0480 |
0.793 |
|
2007 |
Cai C, Chen SY, Zheng Z, Omwancha J, Lin MF, Balk SP, Shemshedini L. Androgen regulation of soluble guanylyl cyclasealpha1 mediates prostate cancer cell proliferation. Oncogene. 26: 1606-15. PMID 16964290 DOI: 10.1038/Sj.Onc.1209956 |
0.806 |
|
2006 |
Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP. Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proceedings of the National Academy of Sciences of the United States of America. 103: 15969-74. PMID 17043241 DOI: 10.1073/Pnas.0604193103 |
0.593 |
|
2006 |
Xu Y, Chen SY, Ross KN, Balk SP. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins Cancer Research. 66: 7783-7792. PMID 16885382 DOI: 10.1158/0008-5472.Can-05-4472 |
0.572 |
|
2006 |
Omwancha J, Zhou XF, Chen SY, Baslan T, Fisher CJ, Zheng Z, Cai C, Shemshedini L. Makorin RING finger protein 1 (MKRN1) has negative and positive effects on RNA polymerase II-dependent transcription. Endocrine. 29: 363-73. PMID 16785614 DOI: 10.1385/Endo:29:2:363 |
0.733 |
|
2006 |
Chen SY, Cai C, Fisher CJ, Zheng Z, Omwancha J, Hsieh CL, Shemshedini L. c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation. Oncogene. 25: 7212-23. PMID 16732317 DOI: 10.1038/sj.onc.1209705 |
0.794 |
|
2006 |
Chen SY, Wulf G, Zhou XZ, Rubin MA, Lu KP, Balk SP. Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Molecular and Cellular Biology. 26: 929-39. PMID 16428447 DOI: 10.1128/Mcb.26.3.929-939.2006 |
0.455 |
|
2006 |
Zheng Z, Cai C, Omwancha J, Chen SY, Baslan T, Shemshedini L. SUMO-3 enhances androgen receptor transcriptional activity through a sumoylation-independent mechanism in prostate cancer cells. The Journal of Biological Chemistry. 281: 4002-12. PMID 16361251 DOI: 10.1074/Jbc.M509260200 |
0.806 |
|
2004 |
Masiello D, Chen S, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, Balk SP. Recruitment of β-Catenin by Wild-Type or Mutant Androgen Receptors Correlates with Ligand-Stimulated Growth of Prostate Cancer Cells Molecular Endocrinology. 18: 2388-2401. PMID 15256534 DOI: 10.1210/Me.2003-0436 |
0.649 |
|
2004 |
Salas TR, Kim J, Vakar-Lopez F, Sabichi AL, Troncoso P, Jenster G, Kikuchi A, Chen SY, Shemshedini L, Suraokar M, Logothetis CJ, DiGiovanni J, Lippman SM, Menter DG. Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity. The Journal of Biological Chemistry. 279: 19191-200. PMID 14985354 DOI: 10.1074/Jbc.M309560200 |
0.74 |
|
2001 |
Bubulya A, Chen SY, Fisher CJ, Zheng Z, Shen XQ, Shemshedini L. c-Jun potentiates the functional interaction between the amino and carboxyl termini of the androgen receptor. The Journal of Biological Chemistry. 276: 44704-11. PMID 11577103 DOI: 10.1074/Jbc.M107346200 |
0.74 |
|
2001 |
Shenk JL, Fisher CJ, Chen SY, Zhou XF, Tillman K, Shemshedini L. p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction. The Journal of Biological Chemistry. 276: 38472-9. PMID 11504717 DOI: 10.1074/Jbc.M103652200 |
0.832 |
|
2000 |
Zhou D, Quach KM, Yang C, Lee SY, Pohajdak B, Chen S. PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1). Molecular Endocrinology (Baltimore, Md.). 14: 986-98. PMID 10894149 DOI: 10.1210/Mend.14.7.0480 |
0.325 |
|
1999 |
Lavrovsky Y, Tyagi RK, Chen S, Song CS, Chatterjee B, Roy AK. Ribozyme-mediated cleavage of the estrogen receptor messenger RNA and inhibition of receptor function in target cells. Molecular Endocrinology (Baltimore, Md.). 13: 925-34. PMID 10379891 DOI: 10.1210/Mend.13.6.0302 |
0.381 |
|
1996 |
Chatterjee B, Song CS, Jung MH, Chen S, Walter CA, Herbert DC, Weaker FJ, Mancini MA, Roy AK. Targeted overexpression of androgen receptor with a liver-specific promoter in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 728-33. PMID 8570624 DOI: 10.1073/Pnas.93.2.728 |
0.302 |
|
1995 |
Song CS, Jung MH, Supakar PC, Chen S, Vellanoweth RL, Chatterjee B, Roy AK. Regulation of androgen action by receptor gene inhibition. Annals of the New York Academy of Sciences. 761: 97-108. PMID 7625753 DOI: 10.1111/J.1749-6632.1995.Tb31372.X |
0.41 |
|
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