Shaoyong Chen, Ph.D. - Publications

Affiliations: 
2002 The University of Toledo 
Area:
Molecular Biology, Cell Biology, Oncology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Arai S, Gao Y, Yu Z, Xie L, Wang L, Zhang T, Nouri M, Chen S, Asara JM, Balk SP. A carboxy-terminal ubiquitylation site regulates androgen receptor activity. Communications Biology. 7: 25. PMID 38182874 DOI: 10.1038/s42003-023-05709-x  0.367
2023 Guo J, Wei Z, Jia T, Wang L, Nama N, Liang J, Liao X, Liu X, Gao Y, Liu X, Wang K, Fu B, Chen SS. Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions. Journal of Translational Medicine. 21: 716. PMID 37828515 DOI: 10.1186/s12967-023-04429-4  0.602
2023 Fu B, Wang L, Jia T, Wei Z, Nama N, Liang J, Liao X, Liu X, Gao Y, Liu X, Mao RS, Wang K, Guo J, Chen SS. Androgen receptor and MYC transcriptomes are equilibrated in multilayer regulatory circuitries in prostate cancer. The Prostate. PMID 37565264 DOI: 10.1002/pros.24603  0.544
2023 Wei Z, Wang S, Xu Y, Wang W, Soares F, Ahmed M, Su P, Wang T, Orouji E, Xu X, Zeng Y, Chen S, Liu X, Jia T, Liu Z, ... Chen S, et al. MYC reshapes CTCF-mediated chromatin architecture in prostate cancer. Nature Communications. 14: 1787. PMID 36997534 DOI: 10.1038/s41467-023-37544-3  0.507
2022 Zhang H, Zhang L, Chen S, Yao M, Ma Z, Yuan Y. Yeast-based evolutionary modeling of androgen receptor mutations and natural selection. Plos Genetics. 18: e1010518. PMID 36459502 DOI: 10.1371/journal.pgen.1010518  0.372
2022 Zhang H, Zhang L, Xu Y, Chen S, Ma Z, Yao M, Li F, Li B, Yuan Y. Simulating androgen receptor selection in designer yeast. Synthetic and Systems Biotechnology. 7: 1108-1116. PMID 36017332 DOI: 10.1016/j.synbio.2022.07.005  0.44
2021 Guo H, Wu Y, Nouri M, Spisak S, Russo JW, Sowalsky AG, Pomerantz MM, Wei Z, Korthauer K, Seo JH, Wang L, Arai S, Freedman ML, He HH, Chen S, et al. Androgen receptor and MYC equilibration centralizes on developmental super-enhancer. Nature Communications. 12: 7308. PMID 34911936 DOI: 10.1038/s41467-021-27077-y  0.584
2021 Liang J, Wang L, Poluben L, Nouri M, Arai S, Xie L, Voznesensky OS, Cato L, Yuan X, Russo JW, Long HW, Brown M, Chen S, Balk SP. Androgen receptor splice variant 7 functions independently of the full length receptor in prostate cancer cells. Cancer Letters. PMID 34256096 DOI: 10.1016/j.canlet.2021.07.013  0.585
2021 Gao X, Liang J, Wang L, Zhang Z, Yuan P, Wang J, Gao Y, Ma F, Calagua C, Ye H, Voznesensky O, Wang S, Wang T, Liu J, Chen S, et al. Phosphorylation of the Androgen Receptor at Ser81 is co-sustained by CDK1 and CDK9 and leads to AR-mediated transactivation in prostate cancer. Molecular Oncology. PMID 33932081 DOI: 10.1002/1878-0261.12968  0.557
2020 Canesin G, Di Ruscio A, Li M, Ummarino S, Hedblom A, Choudhury R, Krzyzanowska A, Csizmadia E, Palominos M, Stiehm A, Ebralidze A, Chen SY, Bassal MA, Zhao P, Tolosano E, et al. Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases. Cell Reports. 32: 108181. PMID 32966797 DOI: 10.1016/j.celrep.2020.108181  0.398
2018 Tinzl M, Chen B, Chen SY, Semenas J, Abrahamsson PA, Dizeyi N. Correction: Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer. Plos One. 13: e0209544. PMID 30562402 DOI: 10.1371/journal.pone.0209544  0.442
2018 Russo JW, Liu X, Ye H, Calagua C, Chen S, Voznesensky O, Condulis J, Ma F, Taplin ME, Einstein DJ, Balk SP, Chen S. Phosphorylation of Androgen Receptor Serine 81 is Associated with its Reactivation in Castration-Resistant Prostate Cancer. Cancer Letters. PMID 30217568 DOI: 10.1016/J.Canlet.2018.09.014  0.619
2017 Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, Zhang T, Russo J, Cai C, Yuan X, Liu J, Chen S, Balk SP. Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer. Nucleic Acids Research. PMID 28062857 DOI: 10.1093/Nar/Gkw1291  0.698
2016 Gao S, Gao Y, He HH, Han D, Han W, Avery A, Macoska JA, Liu X, Chen S, Ma F, Chen S, Balk SP, Cai C. Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein. Cell Reports. 17: 966-976. PMID 27760327 DOI: 10.1016/J.Celrep.2016.09.064  0.764
2016 Sun R, Zhang S, Hu W, Lu X, Lou N, Yang Z, Chen S, Zhang X, Yang H. Valproic Acid Attenuates Skeletal Muscle Wasting by Inhibiting C/EBPβ-regulated Atrogin1 Expression in Cancer Cachexia. American Journal of Physiology. Cell Physiology. ajpcell.00344.2015. PMID 27122162 DOI: 10.1152/Ajpcell.00344.2015  0.344
2016 Liu X, Han W, Gulla S, Simon NI, Gao Y, Liu J, Wang L, Yang H, Zhang X, Chen S. Androgen ablation elicits PP1-dependence for AR stabilization and transactivation in prostate cancer. The Prostate. PMID 26847655 DOI: 10.1002/Pros.23157  0.655
2016 Liu X, Gao Y, Cai C, Balk S, Chen S. Abstract A13: Androgen receptor functions as an adaptor protein for recruitment of protein phosphatase 1a to chromatin and CDK9 mobilization Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-A13  0.703
2015 Liu X, Han W, Gulla S, Simon NI, Gao Y, Cai C, Yang H, Zhang X, Liu J, Balk SP, Chen S. Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation. Oncotarget. PMID 26636645 DOI: 10.18632/Oncotarget.6434  0.769
2015 Wang X, Chen X, Han W, Ruan A, Chen L, Wang R, Xu Z, Xiao P, Lu X, Zhao Y, Zhou J, Chen S, Du Q, Yang H, Zhang X. miR-200c Targets CDK2 and Suppresses Tumorigenesis in Renal Cell Carcinoma. Molecular Cancer Research : McR. PMID 26248649 DOI: 10.1158/1541-7786.Mcr-15-0128  0.336
2015 Sowalsky AG, Xia Z, Wang L, Zhao H, Chen S, Bubley GJ, Balk SP, Li W. Whole transcriptome sequencing reveals extensive unspliced mRNA in metastatic castration-resistant prostate cancer. Molecular Cancer Research : McR. 13: 98-106. PMID 25189356 DOI: 10.1158/1541-7786.Mcr-14-0273  0.588
2015 Gao Y, Gao S, He H, Liu X, Chen S, Ma F, Liu XS, Brown M, Balk SP, Chen S, Cai C. Abstract 1849: Androgen receptor transcriptionally represses genes mediating DNA synthesis and repair in prostate cancer Cancer Research. 75: 1849-1849. DOI: 10.1158/1538-7445.Am2015-1849  0.743
2014 Cai C, He HH, Gao S, Chen S, Yu Z, Gao Y, Chen S, Chen MW, Zhang J, Ahmed M, Wang Y, Metzger E, Schüle R, Liu XS, Brown M, et al. Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity. Cell Reports. 9: 1618-27. PMID 25482560 DOI: 10.1016/J.Celrep.2014.11.008  0.683
2014 Hsieh CL, Fei T, Chen Y, Li T, Gao Y, Wang X, Sun T, Sweeney CJ, Lee GS, Chen S, Balk SP, Liu XS, Brown M, Kantoff PW. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7319-24. PMID 24778216 DOI: 10.1073/Pnas.1324151111  0.782
2014 Yang H, Chen X, Wang X, Li Y, Chen S, Qian X, Wang R, Chen L, Han W, Ruan A, Du Q, Olumi AF, Zhang X. Inhibition of PP2A activity confers a TRAIL-sensitive phenotype during malignant transformation. Molecular Cancer Research : McR. 12: 217-27. PMID 24296757 DOI: 10.1158/1541-7786.MCR-13-0441  0.311
2013 Gao Y, Chen S. Proline-Directed Androgen Receptor Phosphorylation. Journal of Molecular and Genetic Medicine : An International Journal of Biomedical Research. 7: 75. PMID 25866551 DOI: 10.4172/1747-0862.1000075  0.339
2013 Tinzl M, Chen B, Chen SY, Semenas J, Abrahamsson PA, Dizeyi N. Interaction between c-jun and androgen receptor determines the outcome of taxane therapy in castration resistant prostate cancer. Plos One. 8: e79573. PMID 24260253 DOI: 10.1371/journal.pone.0079573  0.483
2012 Chen S, Gulla S, Cai C, Balk SP. Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation. The Journal of Biological Chemistry. 287: 8571-83. PMID 22275373 DOI: 10.1074/Jbc.M111.325290  0.698
2012 Sun T, Yang M, Chen S, Balk S, Pomerantz M, Hsieh CL, Brown M, Lee GS, Kantoff PW. The altered expression of MiR-221/-222 and MiR-23b/-27b is associated with the development of human castration resistant prostate cancer. The Prostate. 72: 1093-103. PMID 22127852 DOI: 10.1002/Pros.22456  0.6
2012 Tinzl M, Chen B, Chen S, Abrahamsson P, Dizeyi N. 934 Androgen receptor expression is induced by docetaxel in prostate cancer cells European Urology Supplements. 11: e934-e934a. DOI: 10.1016/S1569-9056(12)60931-2  0.597
2011 Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z, Chen S, Nelson PS, Liu XS, Brown M, Balk SP. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell. 20: 457-71. PMID 22014572 DOI: 10.1016/J.Ccr.2011.09.001  0.767
2011 Cai C, Chen S, Ng P, Bubley GJ, Nelson PS, Mostaghel EA, Marck B, Matsumoto AM, Simon NI, Wang H, Chen S, Balk SP. Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors. Cancer Research. 71: 6503-13. PMID 21868758 DOI: 10.1158/0008-5472.Can-11-0532  0.712
2011 Sun T, Yang M, Chen S, Balk S, Pomerantz M, Brown M, Kantoff PW, Lee GM. Abstract 174: MicroRNA signatures of castration resistant human prostate cancer Cancer Research. 71: 174-174. DOI: 10.1158/1538-7445.Am2011-174  0.385
2011 Tinzl M, Chen B, Fang K, Chen S, Abrahamsson P, Dizeyi N. 941 C-JUN INTERVENES WITH DOCETAXEL THERAPY IN CASTRATION-RESISTANT PROSTATE CANCER: AR STILL MATTERS European Urology Supplements. 10: 294. DOI: 10.1016/S1569-9056(11)60923-8  0.474
2009 Chen S, Kesler CT, Paschal BM, Balk SP. Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1. The Journal of Biological Chemistry. 284: 25576-84. PMID 19622840 DOI: 10.1074/Jbc.M109.043133  0.596
2009 Cai C, Wang H, Xu Y, Chen S, Balk SP. Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Research. 69: 6027-32. PMID 19584279 DOI: 10.1158/0008-5472.Can-09-0395  0.753
2009 Cai C, Portnoy DC, Wang H, Jiang X, Chen S, Balk SP. Androgen receptor expression in prostate cancer cells is suppressed by activation of epidermal growth factor receptor and ErbB2. Cancer Research. 69: 5202-9. PMID 19491261 DOI: 10.1158/0008-5472.Can-09-0026  0.752
2008 Hsieh CL, Cai C, Giwa A, Bivins A, Chen SY, Sabry D, Govardhan K, Shemshedini L. Expression of a hyperactive androgen receptor leads to androgen-independent growth of prostate cancer cells. Journal of Molecular Endocrinology. 41: 13-23. PMID 18469090 DOI: 10.1677/Jme-07-0158  0.855
2007 Cai C, Hsieh CL, Omwancha J, Zheng Z, Chen SY, Baert JL, Shemshedini L. ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion. Molecular Endocrinology (Baltimore, Md.). 21: 1835-46. PMID 17505060 DOI: 10.1210/Me.2006-0480  0.793
2007 Cai C, Chen SY, Zheng Z, Omwancha J, Lin MF, Balk SP, Shemshedini L. Androgen regulation of soluble guanylyl cyclasealpha1 mediates prostate cancer cell proliferation. Oncogene. 26: 1606-15. PMID 16964290 DOI: 10.1038/Sj.Onc.1209956  0.806
2006 Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP. Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proceedings of the National Academy of Sciences of the United States of America. 103: 15969-74. PMID 17043241 DOI: 10.1073/Pnas.0604193103  0.593
2006 Xu Y, Chen SY, Ross KN, Balk SP. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins Cancer Research. 66: 7783-7792. PMID 16885382 DOI: 10.1158/0008-5472.Can-05-4472  0.572
2006 Omwancha J, Zhou XF, Chen SY, Baslan T, Fisher CJ, Zheng Z, Cai C, Shemshedini L. Makorin RING finger protein 1 (MKRN1) has negative and positive effects on RNA polymerase II-dependent transcription. Endocrine. 29: 363-73. PMID 16785614 DOI: 10.1385/Endo:29:2:363  0.733
2006 Chen SY, Cai C, Fisher CJ, Zheng Z, Omwancha J, Hsieh CL, Shemshedini L. c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation. Oncogene. 25: 7212-23. PMID 16732317 DOI: 10.1038/sj.onc.1209705  0.794
2006 Chen SY, Wulf G, Zhou XZ, Rubin MA, Lu KP, Balk SP. Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction. Molecular and Cellular Biology. 26: 929-39. PMID 16428447 DOI: 10.1128/Mcb.26.3.929-939.2006  0.455
2006 Zheng Z, Cai C, Omwancha J, Chen SY, Baslan T, Shemshedini L. SUMO-3 enhances androgen receptor transcriptional activity through a sumoylation-independent mechanism in prostate cancer cells. The Journal of Biological Chemistry. 281: 4002-12. PMID 16361251 DOI: 10.1074/Jbc.M509260200  0.806
2004 Masiello D, Chen S, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, Balk SP. Recruitment of β-Catenin by Wild-Type or Mutant Androgen Receptors Correlates with Ligand-Stimulated Growth of Prostate Cancer Cells Molecular Endocrinology. 18: 2388-2401. PMID 15256534 DOI: 10.1210/Me.2003-0436  0.649
2004 Salas TR, Kim J, Vakar-Lopez F, Sabichi AL, Troncoso P, Jenster G, Kikuchi A, Chen SY, Shemshedini L, Suraokar M, Logothetis CJ, DiGiovanni J, Lippman SM, Menter DG. Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity. The Journal of Biological Chemistry. 279: 19191-200. PMID 14985354 DOI: 10.1074/Jbc.M309560200  0.74
2001 Bubulya A, Chen SY, Fisher CJ, Zheng Z, Shen XQ, Shemshedini L. c-Jun potentiates the functional interaction between the amino and carboxyl termini of the androgen receptor. The Journal of Biological Chemistry. 276: 44704-11. PMID 11577103 DOI: 10.1074/Jbc.M107346200  0.74
2001 Shenk JL, Fisher CJ, Chen SY, Zhou XF, Tillman K, Shemshedini L. p53 represses androgen-induced transactivation of prostate-specific antigen by disrupting hAR amino- to carboxyl-terminal interaction. The Journal of Biological Chemistry. 276: 38472-9. PMID 11504717 DOI: 10.1074/Jbc.M103652200  0.832
2000 Zhou D, Quach KM, Yang C, Lee SY, Pohajdak B, Chen S. PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1). Molecular Endocrinology (Baltimore, Md.). 14: 986-98. PMID 10894149 DOI: 10.1210/Mend.14.7.0480  0.325
1999 Lavrovsky Y, Tyagi RK, Chen S, Song CS, Chatterjee B, Roy AK. Ribozyme-mediated cleavage of the estrogen receptor messenger RNA and inhibition of receptor function in target cells. Molecular Endocrinology (Baltimore, Md.). 13: 925-34. PMID 10379891 DOI: 10.1210/Mend.13.6.0302  0.381
1996 Chatterjee B, Song CS, Jung MH, Chen S, Walter CA, Herbert DC, Weaker FJ, Mancini MA, Roy AK. Targeted overexpression of androgen receptor with a liver-specific promoter in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 728-33. PMID 8570624 DOI: 10.1073/Pnas.93.2.728  0.302
1995 Song CS, Jung MH, Supakar PC, Chen S, Vellanoweth RL, Chatterjee B, Roy AK. Regulation of androgen action by receptor gene inhibition. Annals of the New York Academy of Sciences. 761: 97-108. PMID 7625753 DOI: 10.1111/J.1749-6632.1995.Tb31372.X  0.41
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