Lynne Cassimeris - Publications

Affiliations: 
Molecular Biology Lehigh University, Bethlehem, PA, United States 
Area:
Cell Biology, Molecular Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Leung JC, Cassimeris L. Reorganization of paclitaxel-stabilized microtubule arrays at mitotic entry: roles of depolymerizing kinesins and severing proteins. Cancer Biology & Therapy. 1-11. PMID 31345098 DOI: 10.1080/15384047.2019.1638678  0.548
2018 Cassimeris L, Leung JC, Odde DJ. Monte Carlo simulations of microtubule arrays: The critical roles of rescue transitions, the cell boundary, and tubulin concentration in shaping microtubule distributions. Plos One. 13: e0197538. PMID 29782540 DOI: 10.1371/Journal.Pone.0197538  0.485
2015 Silva VC, Plooster M, Leung JC, Cassimeris L. A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells. Cell Cycle (Georgetown, Tex.). 14: 1070-81. PMID 25602147 DOI: 10.1080/15384101.2015.1007781  0.357
2014 Silva VC, Cassimeris L. CAMSAPs add to the growing microtubule minus-end story. Developmental Cell. 28: 221-2. PMID 24525183 DOI: 10.1016/J.Devcel.2014.01.025  0.431
2014 Thomas NE, Thamkachy R, Sivakumar KC, Sreedevi KJ, Louis XL, Thomas SA, Kumar R, Rajasekharan KN, Cassimeris L, Sengupta S. Reversible action of diaminothiazoles in cancer cells is implicated by the induction of a fast conformational change of tubulin and suppression of microtubule dynamics. Molecular Cancer Therapeutics. 13: 179-89. PMID 24194566 DOI: 10.1158/1535-7163.Mct-13-0479  0.414
2013 Silva VC, Cassimeris L. Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1. Molecular Biology of the Cell. 24: 3819-31. PMID 24152729 DOI: 10.1091/Mbc.E13-02-0108  0.46
2013 Cassimeris L, Guglielmi L, Denis V, Larroque C, Martineau P. Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody. Plos One. 8: e59812. PMID 23555790 DOI: 10.1371/Journal.Pone.0059812  0.514
2012 Nakamura S, Grigoriev I, Nogi T, Hamaji T, Cassimeris L, Mimori-Kiyosue Y. Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells. Plos One. 7: e51442. PMID 23251535 DOI: 10.1371/Journal.Pone.0051442  0.456
2012 Carney BK, Caruso Silva V, Cassimeris L. The microtubule cytoskeleton is required for a G2 cell cycle delay in cancer cells lacking stathmin and p53. Cytoskeleton (Hoboken, N.J.). 69: 278-89. PMID 22407961 DOI: 10.1002/Cm.21024  0.446
2012 Cassimeris L, Silva VC, Miller E, Ton Q, Molnar C, Fong J. Fueled by microtubules: does tubulin dimer/polymer partitioning regulate intracellular metabolism? Cytoskeleton (Hoboken, N.J.). 69: 133-43. PMID 22328323 DOI: 10.1002/Cm.21008  0.374
2011 Carney B, Caruso V, Cassimeris L. Abstract C32: Stathmin depletion from cells lacking p53 delays mitotic entry by increasing microtubule stability during interphase Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C32  0.445
2010 Cassimeris L, Tran P. Microtubules: in vivo. Preface. Methods in Cell Biology. 97: xvii-xviii. PMID 20719261 DOI: 10.1016/S0091-679X(10)97031-3  0.476
2010 Blake-Hodek KA, Cassimeris L, Huffaker TC. Regulation of microtubule dynamics by Bim1 and Bik1, the budding yeast members of the EB1 and CLIP-170 families of plus-end tracking proteins. Molecular Biology of the Cell. 21: 2013-23. PMID 20392838 DOI: 10.1091/Mbc.E10-02-0083  0.518
2010 Carney BK, Cassimeris L. Stathmin/oncoprotein 18, a microtubule regulatory protein, is required for survival of both normal and cancer cell lines lacking the tumor suppressor, p53. Cancer Biology & Therapy. 9: 699-709. PMID 20200495 DOI: 10.4161/Cbt.9.9.11430  0.375
2009 Ringhoff DN, Cassimeris L. Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility. Bmc Genomics. 10: 343. PMID 19643027 DOI: 10.1186/1471-2164-10-343  0.76
2009 Ringhoff DN, Cassimeris L. Stathmin regulates centrosomal nucleation of microtubules and tubulin dimer/polymer partitioning. Molecular Biology of the Cell. 20: 3451-8. PMID 19515833 DOI: 10.1091/Mbc.E09-02-0140  0.781
2009 Cassimeris L, Becker B, Carney B. TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability. Cell Motility and the Cytoskeleton. 66: 535-45. PMID 19373773 DOI: 10.1002/Cm.20359  0.554
2009 Cassimeris L. Microtubule assembly: lattice GTP to the rescue. Current Biology : Cb. 19: R174-6. PMID 19243696 DOI: 10.1016/J.Cub.2008.12.035  0.474
2008 Skibbens RV, Ringhoff DN, Marzillier J, Cassimeris L, Eastman L. Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae. Cell Cycle (Georgetown, Tex.). 7: 3928-34. PMID 19098428 DOI: 10.4161/Cc.7.24.7380  0.734
2008 Mehiri M, Jing B, Ringhoff D, Janout V, Cassimeris L, Regen SL. Cellular entry and nuclear targeting by a highly anionic molecular umbrella. Bioconjugate Chemistry. 19: 1510-3. PMID 18681467 DOI: 10.1021/Bc8001826  0.718
2008 Bartolini F, Moseley JB, Schmoranzer J, Cassimeris L, Goode BL, Gundersen GG. The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. The Journal of Cell Biology. 181: 523-36. PMID 18458159 DOI: 10.1083/Jcb.200709029  0.463
2007 Cassimeris L. Tubulin delivery: polymerization chaperones for microtubule assembly? Developmental Cell. 13: 455-6. PMID 17925218 DOI: 10.1016/J.Devcel.2007.09.009  0.507
2007 Warren JC, Cassimeris L. The contributions of microtubule stability and dynamic instability to adenovirus nuclear localization efficiency. Cell Motility and the Cytoskeleton. 64: 675-89. PMID 17565754 DOI: 10.1002/Cm.20215  0.427
2006 Murphy ME, Cassimeris L. A novel cancer therapy approach targeting microtubule function. Cancer Biology & Therapy. 5: 1721-3. PMID 17224630 DOI: 10.4161/Cbt.5.12.3736  0.313
2006 Warren JC, Rutkowski A, Cassimeris L. Infection with replication-deficient adenovirus induces changes in the dynamic instability of host cell microtubules. Molecular Biology of the Cell. 17: 3557-68. PMID 16775012 DOI: 10.1091/Mbc.E05-09-0850  0.453
2006 Cassimeris L. Mitosis: riding the protofilament curl. Current Biology : Cb. 16: R214-6. PMID 16546076 DOI: 10.1016/J.Cub.2006.02.025  0.334
2005 Becker BE, Cassimeris L. Cytoskeleton: microtubules born on the run. Current Biology : Cb. 15: R551-4. PMID 16051163 DOI: 10.1016/J.Cub.2005.07.006  0.443
2005 VanBuren V, Cassimeris L, Odde DJ. Mechanochemical model of microtubule structure and self-assembly kinetics. Biophysical Journal. 89: 2911-26. PMID 15951387 DOI: 10.1529/Biophysj.105.060913  0.762
2005 Bartolini F, Tian G, Piehl M, Cassimeris L, Lewis SA, Cowan NJ. Identification of a novel tubulin-destabilizing protein related to the chaperone cofactor E. Journal of Cell Science. 118: 1197-207. PMID 15728251 DOI: 10.1242/Jcs.01719  0.774
2004 Cassimeris L. Cell division: eg'ing on microtubule flux. Current Biology : Cb. 14: R1000-2. PMID 15589134 DOI: 10.1016/J.Cub.2004.11.022  0.457
2004 Piehl M, Tulu US, Wadsworth P, Cassimeris L. Centrosome maturation: measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1. Proceedings of the National Academy of Sciences of the United States of America. 101: 1584-8. PMID 14747658 DOI: 10.1073/Pnas.0308205100  0.791
2004 Cassimeris L, Morabito J. TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. Molecular Biology of the Cell. 15: 1580-90. PMID 14718566 DOI: 10.1091/Mbc.E03-07-0544  0.52
2003 Bellows AM, Kenna MA, Cassimeris L, Skibbens RV. Human EFO1p exhibits acetyltransferase activity and is a unique combination of linker histone and Ctf7p/Eco1p chromatid cohesion establishment domains. Nucleic Acids Research. 31: 6334-43. PMID 14576321 DOI: 10.1093/Nar/Gkg811  0.358
2003 Cassimeris L, Skibbens RV. Regulated assembly of the mitotic spindle: a perspective from two ends. Current Issues in Molecular Biology. 5: 99-112. PMID 12866832  0.363
2003 Piehl M, Cassimeris L. Organization and dynamics of growing microtubule plus ends during early mitosis. Molecular Biology of the Cell. 14: 916-25. PMID 12631713 DOI: 10.1091/Mbc.E02-09-0607  0.797
2003 Segerman B, Holmfeldt P, Morabito J, Cassimeris L, Gullberg M. Autonomous and phosphorylation-responsive microtubule-regulating activities of the N-terminus of Op18/stathmin. Journal of Cell Science. 116: 197-205. PMID 12456729 DOI: 10.1242/Jcs.00205  0.419
2002 VanBuren V, Odde DJ, Cassimeris L. Estimates of lateral and longitudinal bond energies within the microtubule lattice. Proceedings of the National Academy of Sciences of the United States of America. 99: 6035-40. PMID 11983898 DOI: 10.1073/Pnas.092504999  0.732
2002 Cassimeris L. The oncoprotein 18/stathmin family of microtubule destabilizers. Current Opinion in Cell Biology. 14: 18-24. PMID 11792540 DOI: 10.1016/S0955-0674(01)00289-7  0.508
2001 Cassimeris L, Gard D, Tran PT, Erickson HP. XMAP215 is a long thin molecule that does not increase microtubule stiffness. Journal of Cell Science. 114: 3025-33. PMID 11686305  0.339
2001 Cassimeris L, Spittle C. Regulation of microtubule-associated proteins. International Review of Cytology. 210: 163-226. PMID 11580206 DOI: 10.1016/S0074-7696(01)10006-9  0.789
2001 Holmfeldt P, Larsson N, Segerman B, Howell B, Morabito J, Cassimeris L, Gullberg M. The catastrophe-promoting activity of ectopic Op18/stathmin is required for disruption of mitotic spindles but not interphase microtubules. Molecular Biology of the Cell. 12: 73-83. PMID 11160824 DOI: 10.1091/Mbc.12.1.73  0.419
2000 Spittle C, Charrasse S, Larroque C, Cassimeris L. The interaction of TOGp with microtubules and tubulin. The Journal of Biological Chemistry. 275: 20748-53. PMID 10770946 DOI: 10.1074/Jbc.M002597200  0.796
1999 Cha B, Cassimeris L, Gard DL. XMAP230 is required for normal spindle assembly in vivo and in vitro. Journal of Cell Science. 112: 4337-46. PMID 10564651  0.416
1999 Howell B, Deacon H, Cassimeris L. Decreasing oncoprotein 18/stathmin levels reduces microtubule catastrophes and increases microtubule polymer in vivo. Journal of Cell Science. 112: 3713-22. PMID 10523507  0.361
1999 Larsson N, Segerman B, Howell B, Fridell K, Cassimeris L, Gullberg M. Op18/stathmin mediates multiple region-specific tubulin and microtubule-regulating activities. The Journal of Cell Biology. 146: 1289-302. PMID 10491392 DOI: 10.1083/Jcb.146.6.1289  0.485
1999 Vasquez RJ, Gard DL, Cassimeris L. Phosphorylation by CDK1 regulates XMAP215 function in vitro. Cell Motility and the Cytoskeleton. 43: 310-21. PMID 10423272 DOI: 10.1002/(Sici)1097-0169(1999)43:4<310::Aid-Cm4>3.0.Co;2-J  0.485
1999 Cassimeris L. Accessory protein regulation of microtubule dynamics throughout the cell cycle. Current Opinion in Cell Biology. 11: 134-41. PMID 10047516 DOI: 10.1016/S0955-0674(99)80017-9  0.549
1999 Larsson N, Segerman B, Gradin HM, Wandzioch E, Cassimeris L, Gullberg M. Mutations of oncoprotein 18/stathmin identify tubulin-directed regulatory activities distinct from tubulin association. Molecular and Cellular Biology. 19: 2242-50. PMID 10022911 DOI: 10.1128/Mcb.19.3.2242  0.44
1999 Howell B, Larsson N, Gullberg M, Cassimeris L. Dissociation of the tubulin-sequestering and microtubule catastrophe-promoting activities of oncoprotein 18/stathmin. Molecular Biology of the Cell. 10: 105-18. PMID 9880330 DOI: 10.1091/Mbc.10.1.105  0.422
1998 Charrasse S, Schroeder M, Gauthier-Rouviere C, Ango F, Cassimeris L, Gard DL, Larroque C. The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215. Journal of Cell Science. 111: 1371-83. PMID 9570755  0.392
1998 Hamill DR, Howell B, Cassimeris L, Suprenant KA. Purification of a WD repeat protein, EMAP, that promotes microtubule dynamics through an inhibition of rescue. The Journal of Biological Chemistry. 273: 9285-91. PMID 9535922 DOI: 10.1074/jbc.273.15.9285  0.443
1997 Moore RC, Zhang M, Cassimeris L, Cyr RJ. In vitro assembled plant microtubules exhibit a high state of dynamic instability. Cell Motility and the Cytoskeleton. 38: 278-86. PMID 9384218 DOI: 10.1002/(Sici)1097-0169(1997)38:3<278::Aid-Cm6>3.0.Co;2-1  0.347
1997 Howell B, Odde DJ, Cassimeris L. Kinase and phosphatase inhibitors cause rapid alterations in microtubule dynamic instability in living cells. Cell Motility and the Cytoskeleton. 38: 201-14. PMID 9331223 DOI: 10.1002/(Sici)1097-0169(1997)38:2<201::Aid-Cm8>3.0.Co;2-9  0.431
1997 Vasquez RJ, Howell B, Yvon AM, Wadsworth P, Cassimeris L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Molecular Biology of the Cell. 8: 973-85. PMID 9201709 DOI: 10.1091/Mbc.8.6.973  0.515
1996 Spittle CS, Cassimeris L. Mechanisms blocking microtubule minus end assembly: evidence for a tubulin dimer-binding protein. Cell Motility and the Cytoskeleton. 34: 324-35. PMID 8871819 DOI: 10.1002/(Sici)1097-0169(1996)34:4<324::Aid-Cm7>3.0.Co;2-7  0.798
1996 Odde DJ, Buettner HM, Cassimeris L. Spectral Analysis of Microtubule Assembly Dynamics Aiche Journal. 42: 1434-1442. DOI: 10.1002/Aic.690420524  0.473
1995 Odde DJ, Cassimeris L, Buettner HM. Kinetics of microtubule catastrophe assessed by probabilistic analysis. Biophysical Journal. 69: 796-802. PMID 8519980 DOI: 10.1016/S0006-3495(95)79953-2  0.344
1995 Vasquez R, Howell B, Yvon A, Wadsworth P, Cassimeris L. Nanomolar Nocodazole Puts The Brakes On Microtubule Dynamic Instability In-Vivo Molecular Biology of the Cell. 6. DOI: 10.7275/R50C4T0S  0.417
1994 Vasquez RJ, Gard DL, Cassimeris L. XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover. The Journal of Cell Biology. 127: 985-93. PMID 7962080 DOI: 10.1083/Jcb.127.4.985  0.503
1993 Cassimeris L. Regulation of microtubule dynamic instability. Cell Motility and the Cytoskeleton. 26: 275-81. PMID 8299143 DOI: 10.1002/Cm.970260402  0.547
1991 Cassimeris L, Salmon ED. Kinetochore microtubules shorten by loss of subunits at the kinetochores of prometaphase chromosomes. Journal of Cell Science. 98: 151-8. PMID 2055954  0.39
1990 Cassimeris L, Rieder CL, Rupp G, Salmon ED. Stability of microtubule attachment to metaphase kinetochores in PtK1 cells. Journal of Cell Science. 96: 9-15. PMID 2197288  0.419
1988 Cassimeris L, Pryer NK, Salmon ED. Real-time observations of microtubule dynamic instability in living cells. The Journal of Cell Biology. 107: 2223-31. PMID 3198684  0.38
1988 Cassimeris L, Inoué S, Salmon ED. Microtubule dynamics in the chromosomal spindle fiber: analysis by fluorescence and high-resolution polarization microscopy. Cell Motility and the Cytoskeleton. 10: 185-96. PMID 3180243 DOI: 10.1002/cm.970100123  0.364
1986 Rieder CL, Davison EA, Jensen LC, Cassimeris L, Salmon ED. Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindle. The Journal of Cell Biology. 103: 581-91. PMID 3733881 DOI: 10.1083/Jcb.103.2.581  0.358
1986 Cassimeris LU, Wadsworth P, Salmon ED. Dynamics of microtubule depolymerization in monocytes. The Journal of Cell Biology. 102: 2023-32. PMID 3519619  0.445
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