Dirk Menche - Publications

Affiliations: 
2005-2008 Helmholtz Centre for Infection Research 
 2008-2011 Organisch-Chemisches Institut Ruprecht-Karls-Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany 
 2011- Kekulé-Institut für Organische Chemie und Biochemie Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Nordrhein-Westfalen, Germany 
Website:
https://www.menche.uni-bonn.de/

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Meringdal JW, Bade L, Bendas G, Menche D. Diversity Oriented Synthesis of Novel Xanthones Reveal Potent Doxorubicin-Inspired Analogs. Chemmedchem. e202400055. PMID 38351738 DOI: 10.1002/cmdc.202400055  0.348
2023 Babczyk A, Menche D. Total Synthesis of Pentamycin by a Conformationally Biased Double Stille Ring Closure with a Trienyl-bis-stannane. Journal of the American Chemical Society. 145: 10974-10979. PMID 37162233 DOI: 10.1021/jacs.3c03011  0.375
2022 Gao X, Menche D. Sequential Methods for Di- and Tetrahydro-Pyranone Synthesis Enable Concise Access to Tuscolid δ-Lactone. Chemistry, An Asian Journal. PMID 36541601 DOI: 10.1002/asia.202201193  0.395
2022 Estévez-Gallego J, Álvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, Martínez JC, Lucena-Agell D, Prota AE, Bonato F, Bargsten K, Cornelus J, Giménez-Abián JF, Northcote P, Steinmetz MO, et al. Chemical modulation of microtubule structure through the laulimalide/peloruside site. Structure (London, England : 1993). PMID 36462501 DOI: 10.1016/j.str.2022.11.006  0.375
2022 Meringdal JW, Kilian A, Li WC, Heinemann MJB, Rausch M, Schneider T, Menche D. Modular Synthesis of Halogenated Xanthones by a Divergent Coupling Strategy. The Journal of Organic Chemistry. PMID 35776916 DOI: 10.1021/acs.joc.2c01157  0.318
2021 Scheeff S, Rivière S, Ruiz J, Dedenbach S, Menche D. Modular Total Synthesis of -Archazolids and Archazologs. The Journal of Organic Chemistry. PMID 34293866 DOI: 10.1021/acs.joc.1c00946  0.419
2021 Scheeff S, Rivière S, Ruiz J, Dedenbach S, Menche D. Modular Total Synthesis of -Archazolids and Archazologs. The Journal of Organic Chemistry. PMID 34293866 DOI: 10.1021/acs.joc.1c00946  0.419
2020 Wollnitzke P, Essig S, Gölz JP, von Schwarzenberg K, Menche D. Total Synthesis of Ajudazol A by a Modular Oxazole Diversification Strategy. Organic Letters. 22: 6344-6348. PMID 32806171 DOI: 10.1021/Acs.Orglett.0C02188  0.787
2020 Wosniok PR, Knopf C, Dreisigacker S, Orozco-Rodriguez JM, Hinkelmann B, Müller PP, Brönstrup M, Menche D. SAR Studies of the Leupyrrins: Design and Total Synthesis of Highly Potent Simplified Leupylogs. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32608026 DOI: 10.1002/Chem.202002622  0.489
2020 Wingen L, Rausch M, Schneider T, Menche D. Modular Total Synthesis of Farnesyl Analogs of Cell Wall Precursors Lipid I and II, Containing the S. aureus Pentaglycine Bridge Modification. The Journal of Organic Chemistry. PMID 32571025 DOI: 10.1021/Acs.Joc.0C01004  0.389
2020 Wingen LM, Rausch M, Schneider T, Menche D. Synthesis of Tetramic Acid Fragments Derived from Vancoresmycin Showing Inhibitory Effects Towards S. aureus. Chemmedchem. PMID 32497343 DOI: 10.1002/Cmdc.202000241  0.333
2020 Menche D, Rivière S, Vielmuth C, Ennenbach C, Abdelrahman A, Lemke C, Gütschow M, Müller CE. Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids. Chemmedchem. PMID 32363789 DOI: 10.1002/Cmdc.202000154  0.421
2020 Scheeff S, Rivière S, Ruiz J, Abdelrahman A, Schulz-Fincke AC, Köse M, Tiburcy F, Wieczorek H, Gütschow M, Müller CE, Menche D. Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs. Journal of Medicinal Chemistry. PMID 31990540 DOI: 10.1021/Acs.Jmedchem.9B01887  0.382
2019 Göricke B, Bieber MF, Mohr KE, Menche D. Stereochemical Determination of Tuscolid/Tuscorons and Total Synthesis of Tuscoron D and E: Insights into the Tuscolid/Tuscoron Rearrangement. Angewandte Chemie (International Ed. in English). PMID 31347233 DOI: 10.1002/Anie.201906166  0.372
2019 Palm A, Knopf C, Schmalzbauer B, Menche D. Enantioselective Total Synthesis of (+)-Salimabromide Reveals Almost Racemic Nature of Natural Salimabromide. Organic Letters. 21: 1939-1942. PMID 30840465 DOI: 10.1021/Acs.Orglett.9B00706  0.469
2018 Scheeff S, Menche D. Total Synthesis of Archazolid F. Organic Letters. PMID 30548075 DOI: 10.1021/Acs.Orglett.8B03715  0.426
2017 Scheeff S, Menche D. Total syntheses of the archazolids: an emerging class of novel anticancer drugs. Beilstein Journal of Organic Chemistry. 13: 1085-1098. PMID 28684988 DOI: 10.3762/Bjoc.13.108  0.421
2017 Thiede S, Wosniok PR, Herkommer D, Debnar T, Tian M, Wang T, Schrempp M, Menche D. Cover Picture: Total Synthesis of Leupyrrins A1 and B1 , Highly Potent Antifungal Agents from the Myxobacterium Sorangium cellulosum (Chem. Eur. J. 14/2017) Chemistry - a European Journal. 23: 3222-3222. DOI: 10.1002/Chem.201605970  0.588
2016 Thiede S, Wosniok PR, Herkommer D, Debnar T, Tian M, Wang T, Schrempp M, Menche D. Total Synthesis of Leupyrrins A1 and B1, Highly Potent Antifungal Agents from the Myxobacterium Sorangium cellulosum. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27906488 DOI: 10.1002/Chem.201604445  0.813
2016 Thiede S, Wosniok PR, Herkommer D, Schulz-Fincke AC, Gütschow M, Menche D. Total Synthesis of Leupyrrin B1: A Potent Inhibitor of Human Leukocyte Elastase. Organic Letters. PMID 27486674 DOI: 10.1021/Acs.Orglett.6B01724  0.772
2016 Bretzke S, Scheeff S, Vollmeyer F, Eberhagen F, Rominger F, Menche D. Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji-Trost coupling. Beilstein Journal of Organic Chemistry. 12: 1111-21. PMID 27340499 DOI: 10.3762/Bjoc.12.107  0.478
2016 Gölz JP, NejatyJahromy Y, Bauer M, Muhammad A, Schnakenburg G, Grimme S, Schiemann O, Menche D. Design, Synthesis, EPR-Studies and Conformational Bias of Novel Spin-Labeled DCC-Analogues for the Highly Regioselective Labeling of Aliphatic and Aromatic Carboxylic Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27272435 DOI: 10.1002/Chem.201600528  0.768
2016 Essig S, Menche D. Stereoselective Synthesis of Isochromanones by an Asymmetric Ortho-Lithiation Strategy: Synthetic Access to the Isochromanone Core of the Ajudazols. The Journal of Organic Chemistry. 81: 1943-66. PMID 26824669 DOI: 10.1021/Acs.Joc.5B02781  0.478
2016 Essig S, Schmalzbauer B, Bretzke S, Scherer O, Koeberle A, Werz O, Müller R, Menche D. Predictive Bioinformatic Assignment of Methyl-Bearing Stereocenters, Total Synthesis, and an Additional Molecular Target of Ajudazol B. The Journal of Organic Chemistry. 81: 1333-57. PMID 26796481 DOI: 10.1021/Acs.Joc.5B02844  0.485
2016 Thiede S, Winterscheid PM, Hartmann J, Schnakenburg G, Essig S, Menche D. Regiodivergent Iodocyclizations for the Highly Diastereoselective Synthesis of syn - And anti -Hydroxyl-Isochromanones and -Isobenzofuranones: Concise Synthesis of the Isochromanone Core of the Ajudazols Synthesis (Germany). 48: 697-709. DOI: 10.1055/S-0035-1561278  0.471
2016 Menche D. Stereoselective Synthesis of Isochromanones with and Without Activated Spin Intermediates: Total Synthesis of Ajudazol B Strategies and Tactics in Organic Synthesis. 12: 193-213. DOI: 10.1016/B978-0-08-100756-3.00007-8  0.52
2016 Gölz JP, Bockelmann S, Mayer K, Steinhoff H, Wieczorek H, Huss M, Klare JP, Menche D. Back Cover: EPR Studies of V-ATPase with Spin-Labeled Inhibitors DCC and Archazolid: Interaction Dynamics with Proton Translocating Subunit c (ChemMedChem 4/2016) Chemmedchem. 11: 444-444. DOI: 10.1002/Cmdc.201600047  0.736
2016 Menche D. Applications of Domino Transformations in Organic Synthesis. Volumes 1 and 2. Science of Synthesis Workbench Edition. Edited by Scott A. Snyder. Angewandte Chemie International Edition. 55: 12953-12953. DOI: 10.1002/Anie.201608357  0.361
2016 Menche D. Applications of Domino Transformations in Organic Synthesis. Band 1 und 2. Science of Synthesis Workbench Edition. Herausgegeben von Scott A. Snyder. Angewandte Chemie. 128: 13145-13145. DOI: 10.1002/Ange.201608357  0.342
2015 Gölz JP, Bockelmann S, Mayer K, Steinhoff HJ, Wieczorek H, Huss M, Klare JP, Menche D. EPR Studies of V-ATPase with Spin-Labeled Inhibitors DCC and Archazolid: Interaction Dynamics with Proton Translocating Subunit c. Chemmedchem. PMID 26662886 DOI: 10.1002/Cmdc.201500500  0.756
2015 Schrempp M, Thiede S, Herkommer D, Gansäuer A, Menche D. Synthesis of α-Chiral Butyrolactones by Highly Stereoselective Radical Transfer or Sequential Asymmetric Alkylations: Concise Preparation of Leupyrrin Moieties. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 16266-71. PMID 26354047 DOI: 10.1002/Chem.201502263  0.786
2015 Wang T, Schrempp M, Berndhäuser A, Schiemann O, Menche D. Efficient and General Aerobic Oxidative Cross-Coupling of THIQs with Organozinc Reagents Catalyzed by CuCl2: Proof of a Radical Intermediate. Organic Letters. PMID 26252357 DOI: 10.1021/Acs.Orglett.5B01845  0.6
2015 Schmalzbauer B, Menche D. Concise Synthesis of the Tricyclic Core of Salimabromide. Organic Letters. 17: 2956-9. PMID 26020357 DOI: 10.1021/Acs.Orglett.5B01231  0.461
2015 Herkommer D, Thiede S, Wosniok PR, Dreisigacker S, Tian M, Debnar T, Irschik H, Menche D. Stereochemical determination of the leupyrrins and total synthesis of leupyrrin A1. Journal of the American Chemical Society. 137: 4086-9. PMID 25769018 DOI: 10.1021/Jacs.5B01894  0.785
2015 Herkommer D, Dreisigacker S, Sergeev G, Sasse F, Gohlke H, Menche D. Design, synthesis, and biological evaluation of simplified side chain hybrids of the potent actin binding polyketides rhizopodin and bistramide. Chemmedchem. 10: 470-89. PMID 25641798 DOI: 10.1002/Cmdc.201402508  0.749
2014 Herkommer D, Schmalzbauer B, Menche D. Sequential catalysis for stereoselective synthesis of complex polyketides. Natural Product Reports. 31: 456-67. PMID 24362363 DOI: 10.1039/C3Np70093C  0.78
2014 Debnar T, Menche D. Sequential Catalysis for the Stereoselective Synthesis of Complex Polyketides Molecular Catalysts: Structure and Functional Design. 299-312. DOI: 10.1002/9783527673278.ch14  0.357
2013 Kretschmer M, Dieckmann M, Li P, Rudolph S, Herkommer D, Troendlin J, Menche D. Modular total synthesis of rhizopodin: a highly potent G-actin dimerizing macrolide. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 15993-6018. PMID 24123414 DOI: 10.1002/Chem.201302197  0.801
2013 Felder S, Dreisigacker S, Kehraus S, Neu E, Bierbaum G, Wright PR, Menche D, Schäberle TF, König GM. Salimabromide: unexpected chemistry from the obligate marine myxobacterium Enhygromxya salina. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 9319-24. PMID 23703738 DOI: 10.1002/Chem.201301379  0.321
2013 Debnar T, Wang T, Menche D. Stereoselective synthesis of the butyrolactone and the oxazoline/furan fragment of leupyrrin A(1). Organic Letters. 15: 2774-7. PMID 23682963 DOI: 10.1021/Ol401110X  0.635
2013 Schmalzbauer B, Herrmann J, Müller R, Menche D. Total synthesis and antibacterial activity of dysidavarone A. Organic Letters. 15: 964-7. PMID 23391209 DOI: 10.1021/Ol400156U  0.453
2013 Dieckmann M, Menche D. Stereoselective synthesis of 1,3-anti diols by an Ipc-mediated domino aldol-coupling/reduction sequence. Organic Letters. 15: 228-31. PMID 23259690 DOI: 10.1021/Ol3033303  0.443
2013 Debnar T, Dreisigacker S, Menche D. Highly regioselective opening of zirconacyclopentadienes by remote coordination: concise synthesis of the furan core of the leupyrrins. Chemical Communications (Cambridge, England). 49: 725-7. PMID 23230573 DOI: 10.1039/C2Cc37678D  0.458
2013 Altendorfer M, Raja A, Sasse F, Irschik H, Menche D. Modular synthesis of polyene side chain analogues of the potent macrolide antibiotic etnangien by a flexible coupling strategy based on hetero-bis-metallated alkenes. Organic & Biomolecular Chemistry. 11: 2116-39. PMID 23196931 DOI: 10.1039/C2Ob26906F  0.447
2013 Essig S, Menche D. Stereochemistry and total synthesis of complex myxobacterial macrolides Pure and Applied Chemistry. 85: 1103-1120. DOI: 10.1351/Pac-Con-12-09-12  0.468
2013 Dieckmann M, Rudolph S, Lang C, Ahlbrecht W, Menche D. Studies on C18-C20 aldol couplings of rhizopodin Synthesis (Germany). 45: 2305-2315. DOI: 10.1055/S-0033-1338493  0.424
2013 Tang B, Wang L, Menche D. Diastereoselective synthesis of 1,3- Syn -oxazines via a tandem hemiaminalization and Tsuji-Trost reaction Synlett. 24: 625-629. DOI: 10.1055/S-0032-1318300  0.479
2012 Dieckmann M, Rudolph S, Dreisigacker S, Menche D. Concise synthesis of the macrocyclic core of rhizopodin by a Heck macrocyclization strategy. The Journal of Organic Chemistry. 77: 10782-8. PMID 23157362 DOI: 10.1021/Jo302134Y  0.486
2012 Wang L, Menche D. Construction of multisubstituted tetrahydropyrans by a domino oxa-Michael/Tsuji-Trost reaction. The Journal of Organic Chemistry. 77: 10811-23. PMID 23140526 DOI: 10.1021/Jo302102X  0.419
2012 Essig S, Bretzke S, Müller R, Menche D. Full stereochemical determination of ajudazols A and B by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy. Journal of the American Chemical Society. 134: 19362-5. PMID 23127125 DOI: 10.1021/Ja309685N  0.403
2012 Persch E, Basile T, Bockelmann S, Huss M, Wieczorek H, Carlomagno T, Menche D. Synthesis and biological evaluation of a water-soluble derivative of the potent V-ATPase inhibitor archazolid. Bioorganic & Medicinal Chemistry Letters. 22: 7735-8. PMID 23122818 DOI: 10.1016/J.Bmcl.2012.09.081  0.331
2012 Wang L, Menche D. Concise synthesis of acetal-protected syn 1,3-diols by a tandem hemiacetal formation/Tsuji-Trost reaction. Angewandte Chemie (International Ed. in English). 51: 9425-7. PMID 22893592 DOI: 10.1002/Anie.201203911  0.492
2012 Altendorfer M, Irschik H, Menche D. Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien. Bioorganic & Medicinal Chemistry Letters. 22: 5731-4. PMID 22832317 DOI: 10.1016/J.Bmcl.2012.06.070  0.322
2012 Altendorfer M, Menche D. Efficient synthesis of diverse hetero-bis-metallated alkenes as modular reagents towards highly conjugated and isolated olefinic systems. Chemical Communications (Cambridge, England). 48: 8267-9. PMID 22797531 DOI: 10.1039/C2Cc34052F  0.438
2012 Dreisigacker S, Latek D, Bockelmann S, Huss M, Wieczorek H, Filipek S, Gohlke H, Menche D, Carlomagno T. Understanding the inhibitory effect of highly potent and selective archazolides binding to the vacuolar ATPase. Journal of Chemical Information and Modeling. 52: 2265-72. PMID 22747331 DOI: 10.1021/Ci300242D  0.308
2012 Dieckmann M, Kretschmer M, Li P, Rudolph S, Herkommer D, Menche D. Total synthesis of rhizopodin. Angewandte Chemie (International Ed. in English). 51: 5667-70. PMID 22532514 DOI: 10.1002/anie.201201946  0.78
2012 Kretschmer M, Menche D. Stereocontrolled synthesis of the C8-C22 fragment of rhizopodin. Organic Letters. 14: 382-5. PMID 22149453 DOI: 10.1021/Ol203130B  0.406
2012 Wang L, Menche D. Kurze Synthese von Acetal-geschützten 1,3-syn-Diolen durch einen Tandemprozess aus Halbacetalbildung und Tsuji-Trost-Reaktion Angewandte Chemie. 124: 9559-9562. DOI: 10.1002/Ange.201203911  0.385
2011 Horstmann N, Essig S, Bockelmann S, Wieczorek H, Huss M, Sasse F, Menche D. Archazolid A-15-O-β-D-glucopyranoside and iso-archazolid B: potent V-ATPase inhibitory polyketides from the myxobacteria Cystobacter violaceus and Archangium gephyra. Journal of Natural Products. 74: 1100-5. PMID 21513292 DOI: 10.1021/Np200036V  0.314
2011 Menche D, Wang L, Li P. Domino Synthesis of Complex Tetrahydropyrans Synfacts. 2011: 0181-0181. DOI: 10.1055/S-0030-1259334  0.382
2011 Menche D, Essig S. Classics in Total Synthesis III. Further Targets, Strategies, Methods. Von K. C. Nicolaou und Jason S. Chen. Angewandte Chemie. 123: 6119-6120. DOI: 10.1002/Ange.201103334  0.32
2010 Wang L, Li P, Menche D. Concise synthesis of tetrahydropyrans by a tandem oxa-Michael/Tsuji-Trost reaction. Angewandte Chemie (International Ed. in English). 49: 9270-3. PMID 20979071 DOI: 10.1002/Anie.201003304  0.564
2010 Morgen M, Bretzke S, Li P, Menche D. Stereodivergent synthesis of 1,3-syn- and -anti-tetrahydropyrimidinones. Organic Letters. 12: 4494-7. PMID 20831256 DOI: 10.1021/Ol101755M  0.522
2010 Li P, Li J, Arikan F, Ahlbrecht W, Dieckmann M, Menche D. Stereoselective total synthesis of etnangien and etnangien methyl ester. The Journal of Organic Chemistry. 75: 2429-44. PMID 20334428 DOI: 10.1021/Jo100201F  0.564
2010 Menche D, Li P, Irschik H. Design, synthesis and biological evaluation of simplified analogues of the RNA polymerase inhibitor etnangien. Bioorganic & Medicinal Chemistry Letters. 20: 939-41. PMID 20045639 DOI: 10.1016/J.Bmcl.2009.12.066  0.455
2010 Kretschmer M, Menche D. Recent advances in the stereochemical determination and total synthesis of myxobacterial polyketides Synlett. 2989-3007. DOI: 10.1055/S-0030-1259070  0.464
2010 Menche D, Morgen M, Bretzke S, Li P. Synthesis of 1,3-synand -anti-Tetrahydro-pyrimidinones Synfacts. 2010: 1380-1380. DOI: 10.1055/S-0030-1258884  0.383
2010 Bringmann G, Menche D, Brun R, Msuta T, Abegaz B. ChemInform Abstract: Novel Concepts in Directed Biaryl Synthesis. Part 98. Bulbine-Knipholone (I), a New, Axially Chiral Phenylanthraquinone from Bulbine abyssinica (Asphodelaceae): Isolation, Structural Elucidation, Synthesis, and Antiplasmodial Activity Cheminform. 33: no-no. DOI: 10.1002/chin.200230252  0.499
2010 Wang L, Li P, Menche D. Kurze Synthese von Tetrahydropyranen durch eine Oxa-Michael-Tsuji-Trost-Tandemreaktion Angewandte Chemie. 122: 9456-9460. DOI: 10.1002/Ange.201003304  0.54
2009 Menche D, Hassfeld J, Li J, Mayer K, Rudolph S. Modular total synthesis of archazolid A and B. The Journal of Organic Chemistry. 74: 7220-9. PMID 19739663 DOI: 10.1021/Jo901565N  0.496
2009 Li P, Li J, Arikan F, Ahlbrecht W, Dieckmann M, Menche D. Total synthesis of etnangien. Journal of the American Chemical Society. 131: 11678-9. PMID 19645468 DOI: 10.1021/Ja9056163  0.566
2009 Li P, Menche D. Cycloadditions in the total synthesis of sporolide B. Angewandte Chemie (International Ed. in English). 48: 5078-80. PMID 19514024 DOI: 10.1002/Anie.200901894  0.547
2009 Li J, Li P, Menche D. An efficient procedure for the direct nucleophilic substitution of the abiko-masamune auxiliary Synlett. 2417-2420. DOI: 10.1055/S-0029-1217819  0.473
2009 Li J, Menche D. Direct methods for stereoselective polypropionate synthesis: A survey Synthesis. 2293-2315. DOI: 10.1055/S-0029-1216881  0.412
2009 Li J, Menche D. Selective deprotection of silyl ethers with sodium periodate Synthesis. 1904-1908. DOI: 10.1055/S-0028-1088062  0.337
2009 Li P, Menche D. Cycloadditionen in der Totalsynthese von Sporolid B Angewandte Chemie. 121: 5180-5182. DOI: 10.1002/Ange.200901894  0.359
2008 Menche D, Arikan F, Perlova O, Horstmann N, Ahlbrecht W, Wenzel SC, Jansen R, Irschik H, Müller R. Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. Journal of the American Chemical Society. 130: 14234-43. PMID 18826315 DOI: 10.1021/Ja804194C  0.379
2008 Menche D. New methods for stereochemical determination of complex polyketides: configurational assignment of novel metabolites from myxobacteria. Natural Product Reports. 25: 905-18. PMID 18820758 DOI: 10.1039/B707989N  0.312
2008 Arikan F, Li J, Menche D. Diastereodivergent aldol reactions of beta-alkoxy ethyl ketones: modular access to (1,4)-syn and -anti polypropionates. Organic Letters. 10: 3521-4. PMID 18630925 DOI: 10.1021/Ol801292T  0.346
2008 Farès C, Hassfeld J, Menche D, Carlomagno T. Simultaneous determination of the conformation and relative configuration of archazolide A by using nuclear overhauser effects, J couplings, and residual dipolar couplings Angewandte Chemie - International Edition. 47: 3722-3726. PMID 18399562 DOI: 10.1002/Anie.200800225  0.302
2007 Menche D, Arikan F, Li J, Rudolph S, Sasse F. Efficient one-pot synthesis of biologically active polysubstituted aromatic amines. Bioorganic & Medicinal Chemistry. 15: 7311-7. PMID 17870540 DOI: 10.1016/J.Bmc.2007.08.048  0.45
2007 Menche D, Hassfeld J, Steinmetz H, Huss M, Wieczorek H, Sasse F. The first hydroxylated archazolid from the myxobacterium Cystobacter violaceus: isolation, structural elucidation and V-ATPase inhibition. The Journal of Antibiotics. 60: 328-31. PMID 17551213 DOI: 10.1038/Ja.2007.43  0.304
2007 Menche D, Hassfeld J, Li J, Rudolph S. Total synthesis of archazolid A. Journal of the American Chemical Society. 129: 6100-1. PMID 17455939 DOI: 10.1021/ja071461o  0.346
2007 Menche D, Hassfeld J, Sasse F, Huss M, Wieczorek H. Design, synthesis, and biological evaluation of novel analogues of archazolid: a highly potent simplified V-ATPase inhibitor. Bioorganic & Medicinal Chemistry Letters. 17: 1732-5. PMID 17239591 DOI: 10.1016/J.Bmcl.2006.12.073  0.37
2007 Sasse F, Menche D. Success in tubulysin D synthesis. Nature Chemical Biology. 3: 87-9. PMID 17235344 DOI: 10.1038/Nchembio0207-87  0.374
2007 Menche D, Arikan F, Li J, Rudolph S. Directed reductive amination of beta-hydroxy-ketones: convergent assembly of the ritonavir/lopinavir core. Organic Letters. 9: 267-70. PMID 17217281 DOI: 10.1021/Ol062715Y  0.379
2007 Menche D, Hassfeld J, Li J, Rudolph S. Synthesis of Archazolid A Synfacts. 2007: 1016-1016. DOI: 10.1055/S-2007-968942  0.463
2007 Menche D, Böhm S, Li J, Rudolph S, Zander W. Tertiary Amine Synthesis via a Thiourea-Catalyzed Reductive Amination Synfacts. 2007: 0436-0436. DOI: 10.1055/S-2007-968353  0.481
2007 Menche D, Böhm S, Li J, Rudolph S, Zander W. Synthesis of hindered tertiary amines by a mild reductive amination procedure Tetrahedron Letters. 48: 365-369. DOI: 10.1016/J.Tetlet.2006.11.082  0.404
2007 Menche D, Hassfeld J, Steinmetz H, Huss M, Wieczorek H, Sasse F. Archazolid-7-O-β-D-glucopyranoside - Isolation, structural elucidation and solution conformation of a novel V-ATPase inhibitor from the myxobacterium Cystobacter violaceus European Journal of Organic Chemistry. 1196-1202. DOI: 10.1002/Ejoc.200600912  0.333
2006 Hassfeld J, Farès C, Steinmetz H, Carlomagno T, Menche D. Stereochemical determination of archazolid A and B, highly potent vacuolar-type ATPase inhibitors from the myxobacterium Archangium gephyra Organic Letters. 8: 4751-4754. PMID 17020294 DOI: 10.1021/Ol061831Y  0.366
2006 Menche D, Hassfeld J, Li J, Menche G, Ritter A, Rudolph S. Hydrogen bond catalyzed direct reductive amination of ketones. Organic Letters. 8: 741-4. PMID 16468756 DOI: 10.1021/Ol053001A  0.317
2006 Menche D, Arikan F. Thiourea-catalyzed direct reductive amination of aldehydes Synlett. 841-844. DOI: 10.1055/S-2006-939052  0.354
2006 Menche D, Hassfeld J, Li J, Menche G, Ritter A, Rudolph S. Thiourea-Catalyzed Reductive Amination of Ketones Synfacts. 2006: 390-390. DOI: 10.1055/S-2006-932101  0.416
2005 Paterson I, Gottschling D, Menche D. Towards the combinatorial synthesis of spongistatin fragment libraries by using asymmetric aldol reactions on solid support. Chemical Communications (Cambridge, England). 3568-70. PMID 16010326 DOI: 10.1039/B505746A  0.589
2005 Paterson I, Menche D, Håkansson AE, Longstaff A, Wong D, Barasoain I, Buey RM, Díaz JF. Design, synthesis and biological evaluation of novel, simplified analogues of laulimalide: modification of the side chain. Bioorganic & Medicinal Chemistry Letters. 15: 2243-7. PMID 15837302 DOI: 10.1016/J.Bmcl.2005.03.018  0.514
2005 Paterson I, Menche D, Britton R, Håkansson AE, Silva-Martínez MA. Conformational studies and solution structure of laulimalide and simplified analogues using NMR spectroscopy and molecular modelling Tetrahedron Letters. 46: 3677-3682. DOI: 10.1016/J.Tetlet.2005.03.149  0.595
2004 Paterson I, Bergmann H, Menche D, Berkessel A. Synthesis of novel 11-desmethyl analogues of laulimalide by Nozaki-Kishi coupling. Organic Letters. 6: 1293-5. PMID 15070320 DOI: 10.1021/Ol049791Q  0.707
2003 Berkessel A, Menche D, Sklorz CA, Schröder M, Paterson I. A highly enantioselective catalyst for the asymmetric Nozaki-Hiyama-Kishi reaction of allylic and vinylic halides. Angewandte Chemie (International Ed. in English). 42: 1032-5. PMID 12616559 DOI: 10.1002/Anie.200390265  0.626
2002 Abegaz BM, Bezabih M, Msuta T, Brun R, Menche D, Mühlbacher J, Bringmann G. Gaboroquinones A and B and 4'-O-demethylknipholone-4'-O-beta-D-glucopyranoside, phenylanthraquinones from the roots of Bulbine frutescens. Journal of Natural Products. 65: 1117-21. PMID 12193014 DOI: 10.1021/Np0201218  0.412
2002 Bringmann G, Menche D, Mühlbacher J, Reichert M, Saito N, Pfeiffer SS, Lipshutz BH. On the verge of axial chirality: atroposelective synthesis of the AB-biaryl fragment of vancomycin. Organic Letters. 4: 2833-6. PMID 12182567 DOI: 10.1021/Ol026182E  0.521
2002 Bringmann G, Menche D, Kraus J, Mühlbacher J, Peters K, Peters EM, Brun R, Bezabih M, Abegaz BM. Atropo-enantioselective total synthesis of knipholone and related antiplasmodial phenylanthraquinones. The Journal of Organic Chemistry. 67: 5595-610. PMID 12153257 DOI: 10.1021/Jo020189S  0.574
2002 Bringmann G, Menche D, Brun R, Msuta T, Abegaz B. Bulbine-knipholone, a new, axially chiral phenylanthraquinone from Bulbine abyssinica (Asphodelaceae): Isolation, structural elucidation, synthesis, and antiplasmodial activity European Journal of Organic Chemistry. 1107-1111. DOI: 10.1002/1099-0690(200203)2002:6<1107::Aid-Ejoc1107>3.0.Co;2-4  0.51
2001 Bringmann G, Menche D. Stereoselective total synthesis of axially chiral natural products via biaryl lactones. Accounts of Chemical Research. 34: 615-24. PMID 11513568 DOI: 10.1021/Ar000106Z  0.571
2001 Bringmann G, Menche D. First, Atropo-Enantioselective Total Synthesis of the Axially Chiral Phenylanthraquinone Natural Products Knipholone and 6'-O-Methylknipholone Novel Concepts in Directed Biaryl Synthesis, Part 93. This work was supported by the Deutsche Forschungsgemeinschaft (grant: SFB 347) and by the Fonds der Chemischen Industrie. We thank Prof. B. M. Abegaz und Dr. M. Bezabih for an authentic sample of 6'-O-methylknipholone and for valuable discussions. We thank J. Kraus for helpful suggestions and V. Barthel for technical support. Part 92: G. Bringmann, J. Hinrichs, K. Peters, E.-M. Peters, J. Org. Chem. 2001, 66, 629-632. Angewandte Chemie (International Ed. in English). 40: 1687-1690. PMID 11353480 DOI: 10.1002/1521-3773(20010504)40:9<1687::AID-ANIE16870>3.0.CO;2-6  0.382
2001 Bringmann G, Menche D. First, atropo-enantioselective total synthesis of the axially chiral phenylanthraquinone natural products knipholone and 6′-O-methylknipholone Angewandte Chemie - International Edition. 40: 1687-1690. DOI: 10.1002/1521-3773(20010504)40:9<1687::Aid-Anie16870>3.0.Co;2-6  0.506
2001 Bringmann G, Menche D. Erste, atrop-enantioselektive Totalsynthese der axial-chiralen Phenylanthrachinon-Naturstoffe Knipholon und 6′-O-Methylknipholon Angewandte Chemie. 113: 1733-1736. DOI: 10.1002/1521-3757(20010504)113:9<1733::Aid-Ange17330>3.0.Co;2-H  0.383
1999 Bringmann G, Menche D, Bezabih M, Abegaz BM, Kaminsky R. Antiplasmodial activity of knipholone and related natural phenylanthraquinones. Planta Medica. 65: 757-8. PMID 10630123 DOI: 10.1055/S-2006-960859  0.444
1999 Bringmann G, Kraus J, Menche D, Messer K. Elucidation of the absolute configuration of knipholone and knipholone anthrone by quantum chemical CD calculations Tetrahedron. 55: 7563-7572. DOI: 10.1016/S0040-4020(99)00391-9  0.414
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