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Todd D. Giorgio - Publications

Affiliations: 
Biomedical Engineering Vanderbilt University, Nashville, TN 
Area:
Biomedical Engineering, Nanotechnology, Oncology, Nanoscience
Website:
https://engineering.vanderbilt.edu/bio/todd-giorgio
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Glass EB, Hoover A, Harris W, Mirafzali Z, Giorgio TD, Wilson A, Yull F. Abstract 4138: Understanding the effects of NF-kappaB signaling on macrophage phenotype to inform therapeutic approaches Cancer Research. 79: 4138-4138. DOI: 10.1158/1538-7445.Am2019-4138  0.342
2018 Jackson MA, Bedingfield SK, Yu F, Stokan ME, Miles RE, Curvino EJ, Hoogenboezem EN, Bonami RH, Patel SS, Kendall PL, Giorgio TD, Duvall CL. Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes. Biomaterials. 192: 245-259. PMID 30458360 DOI: 10.1016/J.Biomaterials.2018.11.010  0.317
2017 Jackson MA, Werfel TA, Curvino EJ, Yu F, Kavanaugh TE, Sarett SM, Dockery MD, Kilchrist KV, Jackson AN, Giorgio TD, Duvall CL. Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol. Acs Nano. PMID 28548843 DOI: 10.1021/Acsnano.7B01110  0.362
2017 Werfel TA, Jackson MA, Kavanaugh TE, Kirkbride KC, Miteva M, Giorgio TD, Duvall C. Combinatorial optimization of PEG architecture and hydrophobic content improves siRNA polyplex stability, pharmacokinetics, and potency in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28366646 DOI: 10.1016/J.Jconrel.2017.03.389  0.332
2017 Cook AL, Carson CS, Marvinney CE, Giorgio TD, Mu RR. Sensing trace levels of molecular species in solution via zinc oxide nanoprobe Raman spectroscopy Journal of Raman Spectroscopy. 48: 1116-1121. DOI: 10.1002/Jrs.5180  0.3
2016 Miller SE, Bell CS, Mejias R, McClain MS, Cover TL, Giorgio TD. Colistin-Functionalized Nanoparticles for the Rapid Capture of Acinetobacter baumannii. Journal of Biomedical Nanotechnology. 12: 1806-19. PMID 29345892 DOI: 10.1166/Jbn.2016.2273  0.33
2016 Ortega RA, Barham W, Sharman K, Tikhomirov O, Giorgio TD, Yull FE. Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions. International Journal of Nanomedicine. 11: 2163-77. PMID 27274241 DOI: 10.2147/Ijn.S93483  0.691
2016 Sarett SM, Werfel TA, Chandra I, Jackson MA, Kavanaugh TE, Hattaway ME, Giorgio TD, Duvall CL. Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing. Biomaterials. 97: 122-132. PMID 27163624 DOI: 10.1016/J.Biomaterials.2016.04.017  0.325
2016 Ortega RA, Barham W, Sharman K, Tikhomirov O, Giorgio TD, Yull FE. Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions International Journal of Nanomedicine. 11: 2163-2177. DOI: 10.2147/IJN.S93483  0.667
2016 Dockery MD, Poorman ME, Chaplin VL, Spears RA, Caskey CF, Grissom WA, Giorgio TD. Abstract A086: Real-time in vivo characterization of spatiotemporal immunotherapeutic response to high intensity focused ultrasound with a novel NF-kB reporter model of human breast cancer Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A086  0.341
2016 Barham W, Wilson A, Ortega R, Saskowski J, Tikhomirov O, Giorgio T, Khabele D, Yull FE. Abstract B70: Targeted activation of macrophages to limit ovarian cancer progression. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-B70  0.643
2016 Dockery M, Poorman M, Dudzinski S, Barham W, Chaplin V, Spears R, Kusunose J, Yull F, Caskey C, Grissom W, Giorgio T. Abstract A06: Novel NF-kB reporter murine model of spontaneous, metastatic breast cancer for spatiotemporal monitoring of local and systemic therapeutic response Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-A06  0.317
2015 Miteva M, Kirkbride KC, Kilchrist KV, Werfel TA, Li H, Nelson CE, Gupta MK, Giorgio TD, Duvall CL. Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers. Biomaterials. 38: 97-107. PMID 25453977 DOI: 10.1016/J.Biomaterials.2014.10.036  0.3
2015 Li H, Miteva M, Kirkbride KC, Cheng MJ, Nelson CE, Simpson EM, Gupta MK, Duvall CL, Giorgio TD. Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery. Biomacromolecules. 16: 192-201. PMID 25414930 DOI: 10.1021/Bm501394M  0.375
2015 Ortega RA, Barham WJ, Kumar B, Tikhomirov O, McFadden ID, Yull FE, Giorgio TD. Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages. Nanoscale. 7: 500-10. PMID 25408159 DOI: 10.1039/C4Nr03962A  0.679
2015 Barham W, Tikhomirov O, Ortega R, Saskowski J, Thompson CS, Wilson A, Blackwell T, Mirafzali Z, Khabele D, Giorgio T, Yull FE. Abstract 294: A novel cancer therapeutic strategy: inducing cytotoxic functions in tumor-associated macrophages Immunology. 75: 294-294. DOI: 10.1158/1538-7445.Am2015-294  0.658
2014 Giorgio TD, Li H, Miteva M, Kirkbride KC, Cheng M, Nelson CE, Duvall CL. Abstract 720: Dual MMP-7-proximity-activated and folate-targeted nanoparticles for siRNA delivery Cancer Research. 74: 720-720. DOI: 10.1158/1538-7445.Am2014-720  0.379
2014 Ortega R, Barham W, Tikhomirov O, Sharman K, Yull F, Giorgio T. Abstract 3630: Immunoengineering of tumor associated macrophages using targeted, siRNA delivering nanoparticles Cancer Research. 74: 3630-3630. DOI: 10.1158/1538-7445.Am2014-3630  0.698
2013 Li H, Yu SS, Miteva M, Nelson CE, Werfel T, Giorgio TD, Duvall CL. Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery. Advanced Functional Materials. 23: 3040-3052. PMID 25214828 DOI: 10.1002/Adfm.201202215  0.734
2013 Evans BC, Nelson CE, Yu SS, Beavers KR, Kim AJ, Li H, Nelson HM, Giorgio TD, Duvall CL. Ex vivo red blood cell hemolysis assay for the evaluation of pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular drugs. Journal of Visualized Experiments : Jove. e50166. PMID 23524982 DOI: 10.3791/50166  0.711
2013 Yu SS, Lau CM, Barham WJ, Onishko HM, Nelson CE, Li H, Smith CA, Yull FE, Duvall CL, Giorgio TD. Macrophage-specific RNA interference targeting via "click", mannosylated polymeric micelles. Molecular Pharmaceutics. 10: 975-87. PMID 23331322 DOI: 10.1021/Mp300434E  0.747
2013 Zachman AL, Crowder SW, Ortiz O, Zienkiewicz KJ, Bronikowski CM, Yu SS, Giorgio TD, Guelcher SA, Kohn J, Sung HJ. Pro-angiogenic and anti-inflammatory regulation by functional peptides loaded in polymeric implants for soft tissue regeneration. Tissue Engineering. Part A. 19: 437-47. PMID 22953721 DOI: 10.1089/Ten.Tea.2012.0158  0.711
2013 Ortega RA, Barham W, Kumar B, Yu SS, Yull F, Giorgio TD. Abstract 3981: Reprogramming tumor associated macrophages toward an anti-tumor phenotype by targeting the NF-κB pathway using novel targeted nanotherapeutics. Cancer Research. 73: 3981-3981. DOI: 10.1158/1538-7445.Am2013-3981  0.775
2012 Yu SS, Lau CM, Thomas SN, Gray Jerome W, Maron DJ, Dickerson JH, Hubbell JA, Giorgio TD. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages International Journal of Nanomedicine. 7: 799-813. PMID 22359457 DOI: 10.2147/Ijn.S28531  0.741
2012 Gupta MK, Walthall JM, Venkataraman R, Crowder SW, Jung DK, Yu SS, Feaster TK, Wang X, Giorgio TD, Hong CC, Baudenbacher FJ, Hatzopoulos AK, Sung H. Correction: Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation Plos One. 7. DOI: 10.1371/annotation/98390aa9-7a14-4b16-bbf9-da5322752b00  0.675
2012 Yu SS, Lau CM, Barham WJ, Onishko HM, Nelson CE, Yull FE, Duvall CL, Giorgio TD. Abstract 2894: Environmentally responsive nanoparticles for the intracellular delivery of RNAi therapeutics into tumor-associated macrophages Cancer Research. 72: 2894-2894. DOI: 10.1158/1538-7445.Am2012-2894  0.761
2012 Ortega RA, Giorgio TD. A mathematical model of superparamagnetic iron oxide nanoparticle magnetic behavior to guide the design of novel nanomaterials Journal of Nanoparticle Research. 14. DOI: 10.1007/S11051-012-1282-X  0.619
2011 Gupta MK, Walthall JM, Venkataraman R, Crowder SW, Jung DK, Yu SS, Feaster TK, Wang X, Giorgio TD, Hong CC, Baudenbacher FJ, Hatzopoulos AK, Sung HJ. Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation. Plos One. 6: e28935. PMID 22216144 DOI: 10.1371/Journal.Pone.0028935  0.704
2011 Yu SS, Koblin RL, Zachman AL, Perrien DS, Hofmeister LH, Giorgio TD, Sung HJ. Physiologically relevant oxidative degradation of oligo(proline) cross-linked polymeric scaffolds. Biomacromolecules. 12: 4357-66. PMID 22017359 DOI: 10.1021/Bm201328K  0.718
2011 Yu SS, Ortega RA, Reagan BW, McPherson JA, Sung HJ, Giorgio TD. Emerging applications of nanotechnology for the diagnosis and management of vulnerable atherosclerotic plaques. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 3: 620-46. PMID 21834059 DOI: 10.1002/Wnan.158  0.75
2011 Bell CS, Yu SS, Giorgio TD. The multistrata nanoparticle: an FeOx/Au core/shell enveloped in a silica-Au shell. Small (Weinheim An Der Bergstrasse, Germany). 7: 1157-62. PMID 21456084 DOI: 10.1002/Smll.201002100  0.722
2011 Yu SS, Scherer RL, Ortega RA, Bell CS, O'Neil CP, Hubbell JA, Giorgio TD. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) Journal of Nanobiotechnology. 9. PMID 21352596 DOI: 10.1186/1477-3155-9-7  0.769
2011 Thomas SN, van der Vlies AJ, O'Neil CP, Reddy ST, Yu SS, Giorgio TD, Swartz MA, Hubbell JA. Engineering complement activation on polypropylene sulfide vaccine nanoparticles Biomaterials. 32: 2194-2203. PMID 21183216 DOI: 10.1016/J.Biomaterials.2010.11.037  0.747
2011 Yu SS, Scherer RL, Ortega RA, Bell CS, O"Neil CP, Hubbell JA, Giorgio TD. Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) (vol 9, pg 7, 2011) Journal of Nanobiotechnology. 9. DOI: 10.1186/1477-3155-9-51  0.731
2011 Bell CS, Yu SS, Giorgio TD. Multistrata Nanoparticles: The Multistrata Nanoparticle: an FeOx/Au Core/Shell Enveloped in a Silica-Au Shell (Small 9/2011) Small. 7: 1157-1157. DOI: 10.1002/Smll.201190031  0.718
2009 Soman C, Giorgio T. Sensitive and multiplexed detection of proteomic antigens via quantum dot aggregation. Nanomedicine : Nanotechnology, Biology, and Medicine. 5: 402-9. PMID 19523417 DOI: 10.1016/J.Nano.2009.01.010  0.755
2009 Smith RA, Giorgio TD. Quantitative measurement of multifunctional quantum dot binding to cellular targets using flow cytometry Cytometry Part A. 75: 465-474. PMID 19034921 DOI: 10.1002/Cyto.A.20677  0.313
2009 Sewell S, Giorgio T. Surface functionalized nanoparticles for proximity-activated detection and imaging of breast cancer. Cancer Research. 69: 6002. DOI: 10.1158/0008-5472.Sabcs-6002  0.353
2009 Sewell SL, Giorgio TD. Synthesis and enzymatic cleavage of dual-ligand quantum dots Materials Science and Engineering C. 29: 1428-1432. DOI: 10.1016/J.Msec.2008.11.015  0.369
2009 Soman C, Giorgio T. Kinetics of molecular recognition mediated nanoparticle self-assembly Nano Research. 2: 78-84. DOI: 10.1007/S12274-009-9005-Z  0.755
2008 Salaklang J, Steitz B, Finka A, O'Neil CP, Moniatte M, van der Vlies AJ, Giorgio TD, Hofmann H, Hubbell JA, Petri-Fink A. Superparamagnetic nanoparticles as a powerful systems biology characterization tool in the physiological context. Angewandte Chemie (International Ed. in English). 47: 7857-60. PMID 18792049 DOI: 10.1002/Anie.200800357  0.34
2008 Smith R, Sewell SL, Giorgio TD. Proximity-activated nanoparticles: in vitro performance of specific structural modification by enzymatic cleavage. International Journal of Nanomedicine. 3: 95-103. PMID 18488420 DOI: 10.2147/Ijn.S2485  0.392
2008 Soman CP, Giorgio TD. Quantum dot self-assembly for protein detection with sub-picomolar sensitivity. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 4399-404. PMID 18335969 DOI: 10.1021/La704078U  0.754
2007 Kuhn SJ, Finch SK, Hallahan DE, Giorgio TD. Facile production of multivalent enzyme-nanoparticle conjugates Journal of Magnetism and Magnetic Materials. 311: 68-72. DOI: 10.1016/J.Jmmm.2006.10.1165  0.31
2006 Kuhn SJ, Hallahan DE, Giorgio TD. Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system. Annals of Biomedical Engineering. 34: 51-8. PMID 16477503 DOI: 10.1007/S10439-005-9004-5  0.343
2006 Kuhn SJ, Finch SK, Hallahan DE, Giorgio TD. Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix. Nano Letters. 6: 306-12. PMID 16464055 DOI: 10.1021/Nl052241G  0.335
2005 Tomlinson ID, Wright DW, Giorgio TD, Blakely RD, Pennycook SJ, Hercules D, Bentzen L, Smith RA, McBride J, Vergne MJ, Rosenthal S. The Quantum Dot nanoconjugate toolbox Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5705: 199-209. DOI: 10.1117/12.606592  0.348
2003 Hallahan D, Geng L, Qu S, Scarfone C, Giorgio T, Donnelly E, Gao X, Clanton J. Integrin-mediated targeting of drug delivery to irradiated tumor blood vessels. Cancer Cell. 3: 63-74. PMID 12559176 DOI: 10.1016/S1535-6108(02)00238-6  0.321
1988 Giorgio TD, Hellums JD. A note on the use of indo-1 in studying shear-induced platelet aggregation Thrombosis Research. 50: 351-356. PMID 3394120 DOI: 10.1016/0049-3848(88)90238-1  0.585
1988 Giorgio TD, Hellums JD. Inhibition of shear stress-induced platelet activation by commercial luminescence reagents Thrombosis Research. 49: 643-647. PMID 3388315 DOI: 10.1016/0049-3848(88)90262-9  0.593
1988 Giorgio TD, Hellums JD. A cone and plate viscometer for the continuous measurement of blood platelet activation Biorheology. 25: 605-624. PMID 3252916 DOI: 10.3233/Bir-1988-25402  0.593
1987 Peterson DM, Stathopoulos NA, Giorgio TD, Hellums JD, Moake JL. Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa. Blood. 69: 625-8. PMID 3492225 DOI: 10.1182/Blood.V69.2.625.Bloodjournal692625  0.591
1986 Giorgio TD, Hellums JD. A note on the use of Quin2 in studying shear-induced platelet aggregation Thrombosis Research. 41: 353-359. PMID 3705013 DOI: 10.1016/0049-3848(86)90246-X  0.598
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