Jonathan D. Steckbeck, Ph.D. - Publications

Affiliations: 
2012 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Biochemistry, Virology Biology, Molecular Biology, Cell Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Huang DB, Brothers KM, Mandell JB, Taguchi M, Alexander PG, Parker DM, Shinabarger D, Pillar C, Morrissey I, Hawser S, Ghahramani P, Dobbins D, Pachuda N, Montelaro R, Steckbeck JD, et al. Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class. Plos One. 17: e0274815. PMID 36112657 DOI: 10.1371/journal.pone.0274815  0.577
2021 Huang D, Pachuda N, Sauer JM, Dobbins D, Steckbeck J. The Engineered Antibiotic Peptide PLG0206 Eliminates Biofilms and Is a Potential Treatment for Periprosthetic Joint Infections. Antibiotics (Basel, Switzerland). 11. PMID 35052918 DOI: 10.3390/antibiotics11010041  0.345
2020 Beumera JH, Guo J, Ray EC, Scemama J, Parise RA, Deslouches B, Steckbeck JD, Montelaro RC, Eiseman JL. Mass Balance Study of the Engineered Cationic Antimicrobial Peptide, WLBU2, Following a Single Intravenous Dose of 14C-WLBU2 in Mice. Current Clinical Pharmacology. PMID 32778037 DOI: 10.2174/1574884715666200810094201  0.749
2017 Hasek ML, Steckbeck JD, Deslouches B, Craigo JK, Montelaro RC. Engineered Cationic Antimicrobial Peptides Containing Cholesterol Interacting Motifs to Target Viral Envelopes Journal of Antivirals & Antiretrovirals. 9. DOI: 10.4172/1948-5964.1000158  0.775
2016 Deslouches B, Hasek ML, Craigo JK, Steckbeck JD, Montelaro RC. Comparative functional properties of engineered cationic antimicrobial peptides (eCAPs) consisting exclusively of tryptophan and either lysine or arginine. Journal of Medical Microbiology. PMID 27046192 DOI: 10.1099/Jmm.0.000258  0.75
2015 Abdelbaqi S, Deslouches B, Steckbeck J, Montelaro R, Reed DS. Novel engineered cationic antimicrobial peptides display broad-spectrum activity against Francisella tularensis, Yersinia pestis, and Burkholderia pseudomallei. Journal of Medical Microbiology. PMID 26673248 DOI: 10.1099/Jmm.0.000209  0.744
2015 Deslouches B, Steckbeck JD, Craigo JK, Doi Y, Burns JL, Montelaro RC. Engineered cationic antimicrobial peptides to overcome multidrug resistance by ESKAPE pathogens. Antimicrobial Agents and Chemotherapy. 59: 1329-33. PMID 25421473 DOI: 10.1128/Aac.03937-14  0.742
2014 Kuhlmann AS, Steckbeck JD, Sturgeon TJ, Craigo JK, Montelaro RC. Unique functional properties of conserved arginine residues in the lentivirus lytic peptide domains of the C-terminal tail of HIV-1 gp41. The Journal of Biological Chemistry. 289: 7630-40. PMID 24497632 DOI: 10.1074/Jbc.M113.529339  0.611
2014 Steckbeck JD, Kuhlmann AS, Montelaro RC. Structural and functional comparisons of retroviral envelope protein C-terminal domains: still much to learn. Viruses. 6: 284-300. PMID 24441863 DOI: 10.3390/V6010284  0.563
2014 Steckbeck JD, Deslouches B, Montelaro RC. Antimicrobial peptides: new drugs for bad bugs? Expert Opinion On Biological Therapy. 14: 11-4. PMID 24206062 DOI: 10.1517/14712598.2013.844227  0.742
2013 Boscia AL, Akabori K, Benamram Z, Michel JA, Jablin MS, Steckbeck JD, Montelaro RC, Nagle JF, Tristram-Nagle S. Membrane structure correlates to function of LLP2 on the cytoplasmic tail of HIV-1 gp41 protein. Biophysical Journal. 105: 657-66. PMID 23931314 DOI: 10.1016/J.Bpj.2013.06.042  0.58
2013 Steckbeck JD, Sun C, Sturgeon TJ, Montelaro RC. Detailed topology mapping reveals substantial exposure of the "cytoplasmic" C-terminal tail (CTT) sequences in HIV-1 Env proteins at the cell surface. Plos One. 8: e65220. PMID 23724133 DOI: 10.1371/Journal.Pone.0065220  0.594
2013 Deslouches B, Steckbeck JD, Craigo JK, Doi Y, Mietzner TA, Montelaro RC. Rational design of engineered cationic antimicrobial peptides consisting exclusively of arginine and tryptophan, and their activity against multidrug-resistant pathogens. Antimicrobial Agents and Chemotherapy. 57: 2511-21. PMID 23507278 DOI: 10.1128/Aac.02218-12  0.758
2013 Steckbeck JD, Kuhlmann AS, Montelaro RC. C-terminal tail of human immunodeficiency virus gp41: functionally rich and structurally enigmatic. The Journal of General Virology. 94: 1-19. PMID 23079381 DOI: 10.1099/Vir.0.046508-0  0.611
2013 Boscia AL, Akabori K, Benamram Z, Michel JA, Steckbeck JD, Jablin MS, Montelaro RC, Nagle JF, Tristram-Nagle S. LLP-2 Domain on the Cytoplasmic Terminal Tail (CTT) of HIV-1 GP41 affects T-Cell but not HIV Virion Membranes Biophysical Journal. 104: 247a. DOI: 10.1016/J.Bpj.2012.11.1389  0.58
2012 Gearhart T, Steckbeck JD, Craigo JK, Montelaro RC. Rate and affinity binding constants determined by SPR spectroscopy reveal differential antigenicity of HIV gp120 and gp140 Retrovirology. 9: 59. DOI: 10.1186/1742-4690-9-S2-P59  0.6
2012 Kuhlmann A, Steckbeck J, Sturgeon T, Craigo J, Montelaro R. The C-terminal tail of HIV-1 envelope: a unique role for conserved LLP arginines in Env functional properties Retrovirology. 9: 325. DOI: 10.1186/1742-4690-9-S2-P325  0.587
2012 Gearhart T, Steckbeck J, Montelaro R, Craigo J. Antigenicity of soluble HIV gp140 trimers reveals differences in solution conformation for differing HIV strains Retrovirology. 9: 313. DOI: 10.1186/1742-4690-9-S2-P313  0.615
2011 Steckbeck JD, Craigo JK, Barnes CO, Montelaro RC. Highly conserved structural properties of the C-terminal tail of HIV-1 gp41 protein despite substantial sequence variation among diverse clades: implications for functions in viral replication. The Journal of Biological Chemistry. 286: 27156-66. PMID 21659530 DOI: 10.1074/Jbc.M111.258855  0.595
2010 Steckbeck JD, Sun C, Sturgeon TJ, Montelaro RC. Topology of the C-terminal tail of HIV-1 gp41: differential exposure of the Kennedy epitope on cell and viral membranes. Plos One. 5: e15261. PMID 21151874 DOI: 10.1371/Journal.Pone.0015261  0.601
2010 Faith SA, Wu Y, Kuhrt D, Steckbeck JD, Craigo JK, Clements JE, Cole KS. Induction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation. Virology. 400: 86-92. PMID 20153009 DOI: 10.1016/J.Virol.2010.01.014  0.473
2010 Steckbeck JD, Sun C, Sturgeon TJ, Montelaro RC. Distinct Topologies For the HIV-1 Transmembrane Glycoprotein gp41 C-Terminal Tail on Cellular and Viral Lipid Membranes Biophysical Journal. 98: 49a. DOI: 10.1016/J.Bpj.2009.12.282  0.592
2009 Steckbeck JD, Sturgeon TJ, Sun C, Montelaro RC. P12-04. Topology of the C-terminal tail of HIV-1 gp41: Differential exposure of the Kennedy epitope on cell and viral membranes Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P170  0.6
2008 Bright RA, Carter DM, Crevar CJ, Toapanta FR, Steckbeck JD, Cole KS, Kumar NM, Pushko P, Smith G, Tumpey TM, Ross TM. Cross-clade protective immune responses to influenza viruses with H5N1 HA and NA elicited by an influenza virus-like particle. Plos One. 3: e1501. PMID 18231588 DOI: 10.1371/Journal.Pone.0001501  0.351
2007 Gupta S, Leutenegger CM, Dean GA, Steckbeck JD, Cole KS, Sparger EE. Vaccination of cats with attenuated feline immunodeficiency virus proviral DNA vaccine expressing gamma interferon. Journal of Virology. 81: 465-73. PMID 17079309 DOI: 10.1128/Jvi.00815-06  0.356
2006 Steckbeck JD, Cole KS. Dissecting the humoral immune response to simian immunodeficiency virus: mechanisms of antibody-mediated virus neutralization. Immunologic Research. 36: 51-60. PMID 17337766 DOI: 10.1385/Ir:36:1:51  0.422
2006 Steckbeck JD, Grieser HJ, Sturgeon T, Taber R, Chow A, Bruno J, Murphy-Corb M, Montelaro RC, Cole KS. Dynamic evolution of antibody populations in a rhesus macaque infected with attenuated simian immunodeficiency virus identified by surface plasmon resonance. Journal of Medical Primatology. 35: 248-60. PMID 16872288 DOI: 10.1111/J.1600-0684.2006.00173.X  0.578
2005 Steckbeck JD, Orlov I, Chow A, Grieser H, Miller K, Bruno J, Robinson JE, Montelaro RC, Cole KS. Kinetic rates of antibody binding correlate with neutralization sensitivity of variant simian immunodeficiency virus strains. Journal of Virology. 79: 12311-20. PMID 16160158 DOI: 10.1128/Jvi.79.19.12311-12320.2005  0.614
2005 Craigo JK, Li F, Steckbeck JD, Durkin S, Howe L, Cook SJ, Issel C, Montelaro RC. Discerning an effective balance between equine infectious anemia virus attenuation and vaccine efficacy. Journal of Virology. 79: 2666-77. PMID 15708986 DOI: 10.1128/Jvi.79.5.2666-2677.2005  0.698
2004 Cole KS, Steckbeck JD, Rowles JL, Desrosiers RC, Montelaro RC. Removal of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3. Journal of Virology. 78: 1525-39. PMID 14722307 DOI: 10.1128/Jvi.78.3.1525-1539.2004  0.732
2003 Li F, Craigo JK, Howe L, Steckbeck JD, Cook S, Issel C, Montelaro RC. A live attenuated equine infectious anemia virus proviral vaccine with a modified S2 gene provides protection from detectable infection by intravenous virulent virus challenge of experimentally inoculated horses. Journal of Virology. 77: 7244-53. PMID 12805423 DOI: 10.1128/Jvi.77.13.7244-7253.2003  0.704
2003 Van Rompay KK, Greenier JL, Cole KS, Earl P, Moss B, Steckbeck JD, Pahar B, Rourke T, Montelaro RC, Canfield DR, Tarara RP, Miller C, McChesney MB, Marthas ML. Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251. Journal of Virology. 77: 179-90. PMID 12477823 DOI: 10.1128/Jvi.77.1.179-190.2003  0.59
2002 Craigo JK, Leroux C, Howe L, Steckbeck JD, Cook SJ, Issel CJ, Montelaro RC. Transient immune suppression of inapparent carriers infected with a principal neutralizing domain-deficient equine infectious anaemia virus induces neutralizing antibodies and lowers steady-state virus replication. The Journal of General Virology. 83: 1353-9. PMID 12029150 DOI: 10.1099/0022-1317-83-6-1353  0.723
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