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Wai-Leung Ng, Ph.D. - Publications

Affiliations: 
2006 Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Microbiology Biology
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Severin GB, Ramliden MS, Ford KC, Van Alst AJ, Sanath-Kumar R, Decker KA, Hsueh BY, Chen G, Yoon SH, Demey LM, O'Hara BJ, Rhoades CR, DiRita VJ, Ng WL, Waters CM. Activation of a CBASS anti-phage system by quorum sensing and folate depletion. Mbio. e0087523. PMID 37623317 DOI: 10.1128/mbio.00875-23  0.731
2023 Huang X, Nero T, Weerasekera R, Matej KH, Hinbest A, Jiang Z, Lee RF, Wu L, Chak C, Nijjer J, Gibaldi I, Yang H, Gamble N, Ng WL, Malaker SA, et al. Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization. Nature Communications. 14: 2104. PMID 37055389 DOI: 10.1038/s41467-023-37660-0  0.373
2022 O'Hara BJ, Alam M, Ng WL. The Vibrio cholerae Seventh Pandemic Islands act in tandem to defend against a circulating phage. Plos Genetics. 18: e1010250. PMID 36026491 DOI: 10.1371/journal.pgen.1010250  0.75
2022 Hsieh ML, Kiel N, Jenkins LMM, Ng WL, Knipling L, Waters CM, Hinton DM. The Vibrio cholerae master regulator for the activation of biofilm biogenesis genes, VpsR, senses both cyclic di-GMP and phosphate. Nucleic Acids Research. 50: 4484-4499. PMID 35438787 DOI: 10.1093/nar/gkac253  0.525
2022 Barrasso K, Chac D, Debela MD, Geigel C, Steenhaut A, Rivera Seda A, Dunmire CN, Harris JB, Larocque RC, Midani FS, Qadri F, Yan J, Weil AA, Ng WL. Impact of a human gut microbe on host colonization through biofilm enhancement. Elife. 11. PMID 35343438 DOI: 10.7554/eLife.73010  0.378
2020 Watve S, Barrasso K, Jung SA, Davis KJ, Hawver LA, Khataokar A, Palaganas RG, Neiditch MB, Perez LJ, Ng WL. Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host. Plos Pathogens. 16: e1008313. PMID 32059031 DOI: 10.1371/Journal.Ppat.1008313  0.303
2018 Severin GB, Ramliden MS, Hawver LA, Wang K, Pell ME, Kieninger AK, Khataokar A, O'Hara BJ, Behrmann LV, Neiditch MB, Benning C, Waters CM, Ng WL. Direct activation of a phospholipase by cyclic GMP-AMP in El Tor . Proceedings of the National Academy of Sciences of the United States of America. PMID 29891656 DOI: 10.1073/Pnas.1801233115  0.742
2015 Jung SA, Chapman CA, Ng WL. Quadruple quorum-sensing inputs control Vibrio cholerae virulence and maintain system robustness. Plos Pathogens. 11: e1004837. PMID 25874462 DOI: 10.1371/journal.ppat.1004837  0.371
2014 Ke X, Miller LC, Ng WL, Bassler BL. CqsA-CqsS quorum-sensing signal-receptor specificity in Photobacterium angustum. Molecular Microbiology. 91: 821-33. PMID 24372841 DOI: 10.1111/Mmi.12502  0.534
2012 Perez LJ, Ng WL, Marano P, Brook K, Bassler BL, Semmelhack MF. Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. Journal of Medicinal Chemistry. 55: 9669-81. PMID 23092313 DOI: 10.1021/Jm300908T  0.533
2012 Ng WL, Perez L, Cong J, Semmelhack MF, Bassler BL. Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. Plos Pathogens. 8: e1002767. PMID 22761573 DOI: 10.1371/journal.ppat.1002767  0.578
2012 Wei Y, Ng WL, Cong J, Bassler BL. Ligand and antagonist driven regulation of the Vibrio cholerae quorum-sensing receptor CqsS. Molecular Microbiology. 83: 1095-108. PMID 22295878 DOI: 10.1111/J.1365-2958.2012.07992.X  0.642
2011 Bolitho ME, Perez LJ, Koch MJ, Ng WL, Bassler BL, Semmelhack MF. Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit. Bioorganic & Medicinal Chemistry. 19: 6906-18. PMID 22001326 DOI: 10.1016/J.Bmc.2011.09.021  0.505
2011 Ng WL, Perez LJ, Wei Y, Kraml C, Semmelhack MF, Bassler BL. Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Molecular Microbiology. 79: 1407-17. PMID 21219472 DOI: 10.1111/J.1365-2958.2011.07548.X  0.655
2011 Wei Y, Perez LJ, Ng WL, Semmelhack MF, Bassler BL. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. Acs Chemical Biology. 6: 356-65. PMID 21197957 DOI: 10.1021/Cb1003652  0.648
2010 Ng WL, Wei Y, Perez LJ, Cong J, Long T, Koch M, Semmelhack MF, Wingreen NS, Bassler BL. Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proceedings of the National Academy of Sciences of the United States of America. 107: 5575-80. PMID 20212168 DOI: 10.1073/Pnas.1001392107  0.614
2009 Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nature Chemical Biology. 5: 891-5. PMID 19838203 DOI: 10.1038/Nchembio.237  0.648
2009 Ng WL, Bassler BL. Bacterial quorum-sensing network architectures. Annual Review of Genetics. 43: 197-222. PMID 19686078 DOI: 10.1146/Annurev-Genet-102108-134304  0.56
2009 Barendt SM, Land AD, Sham LT, Ng WL, Tsui HC, Arnold RJ, Winkler ME. Influences of capsule on cell shape and chain formation of wild-type and pcsB mutants of serotype 2 Streptococcus pneumoniae. Journal of Bacteriology. 191: 3024-40. PMID 19270090 DOI: 10.1128/Jb.01505-08  0.681
2007 Lanie JA, Ng WL, Kazmierczak KM, Andrzejewski TM, Davidsen TM, Wayne KJ, Tettelin H, Glass JI, Winkler ME. Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6. Journal of Bacteriology. 189: 38-51. PMID 17041037 DOI: 10.1128/Jb.01148-06  0.738
2005 Gilmour R, Foster JE, Sheng Q, McClain JR, Riley A, Sun PM, Ng WL, Yan D, Nicas TI, Henry K, Winkler ME. New class of competitive inhibitor of bacterial histidine kinases. Journal of Bacteriology. 187: 8196-200. PMID 16291694 DOI: 10.1128/Jb.187.23.8196-8200.2005  0.553
2005 Ng WL, Tsui HC, Winkler ME. Regulation of the pspA virulence factor and essential pcsB murein biosynthetic genes by the phosphorylated VicR (YycF) response regulator in Streptococcus pneumoniae. Journal of Bacteriology. 187: 7444-59. PMID 16237028 DOI: 10.1128/Jb.187.21.7444-7459.2005  0.606
2005 Valderas MW, Alcantara RB, Baumgartner JE, Bellaire BH, Robertson GT, Ng WL, Richardson JM, Winkler ME, Roop RM. Role of HdeA in acid resistance and virulence in Brucella abortus 2308. Veterinary Microbiology. 107: 307-12. PMID 15863292 DOI: 10.1016/J.Vetmic.2005.01.018  0.591
2005 Gee JM, Valderas MW, Kovach ME, Grippe VK, Robertson GT, Ng WL, Richardson JM, Winkler ME, Roop RM. The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected mice. Infection and Immunity. 73: 2873-80. PMID 15845493 DOI: 10.1128/Iai.73.5.2873-2880.2005  0.599
2004 Ng WL, Winkler ME. Singular structures and operon organizations of essential two-component systems in species of Streptococcus. Microbiology (Reading, England). 150: 3096-8. PMID 15470090 DOI: 10.1099/Mic.0.27550-0  0.51
2004 Ng WL, Kazmierczak KM, Winkler ME. Defective cell wall synthesis in Streptococcus pneumoniae R6 depleted for the essential PcsB putative murein hydrolase or the VicR (YycF) response regulator. Molecular Microbiology. 53: 1161-75. PMID 15306019 DOI: 10.1111/J.1365-2958.2004.04196.X  0.626
2004 Gooding KB, Higgs R, Hodge B, Stauffer E, Heinz B, McKnight K, Phipps K, Shapiro M, Winkler M, Ng WL, Julian RK. High throughput screening of library compounds against an oligonucleotide substructure of an RNA target. Journal of the American Society For Mass Spectrometry. 15: 884-92. PMID 15144978 DOI: 10.1016/J.Jasms.2004.02.010  0.522
2003 Ng WL, Robertson GT, Kazmierczak KM, Zhao J, Gilmour R, Winkler ME. Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in Streptococcus pneumoniae R6. Molecular Microbiology. 50: 1647-63. PMID 14651645 DOI: 10.1046/J.1365-2958.2003.03806.X  0.633
2003 Roop RM, Gee JM, Robertson GT, Richardson JM, Ng WL, Winkler ME. Brucella stationary-phase gene expression and virulence. Annual Review of Microbiology. 57: 57-76. PMID 12730323 DOI: 10.1146/Annurev.Micro.57.030502.090803  0.611
2003 Robertson GT, Ng WL, Gilmour R, Winkler ME. Essentiality of clpX, but not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniae R6. Journal of Bacteriology. 185: 2961-6. PMID 12700276 DOI: 10.1128/Jb.185.9.2961-2966.2003  0.568
2003 Ng WL, Kazmierczak KM, Robertson GT, Gilmour R, Winkler ME. Transcriptional regulation and signature patterns revealed by microarray analyses of Streptococcus pneumoniae R6 challenged with sublethal concentrations of translation inhibitors. Journal of Bacteriology. 185: 359-70. PMID 12486074 DOI: 10.1128/Jb.185.1.359-370.2003  0.577
2002 Robertson GT, Ng WL, Foley J, Gilmour R, Winkler ME. Global transcriptional analysis of clpP mutations of type 2 Streptococcus pneumoniae and their effects on physiology and virulence. Journal of Bacteriology. 184: 3508-20. PMID 12057945 DOI: 10.1128/Jb.184.13.3508-3520.2002  0.625
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