| Year |
Citation |
Score |
| 2023 |
Bajwa P, Kordylewicz K, Bilecz A, Lastra RR, Wroblewski K, Rinkevich Y, Lengyel E, Kenny HA. Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis. Jci Insight. PMID 36795484 DOI: 10.1172/jci.insight.163019 |
0.398 |
|
| 2021 |
Kenny HA, Hart PC, Kordylewicz K, Lal M, Shen M, Kara B, Chen YJ, Grassl N, Alharbi Y, Pattnaik BR, Watters KM, Patankar MS, Ferrer M, Lengyel E. The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis. Cancers. 13. PMID 34439084 DOI: 10.3390/cancers13163931 |
0.349 |
|
| 2021 |
Hart PC, Bajwa P, Kenny HA. Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity. Advances in Experimental Medicine and Biology. 1330: 75-94. PMID 34339031 DOI: 10.1007/978-3-030-73359-9_5 |
0.445 |
|
| 2021 |
Cui C, Chakraborty K, Tang XA, Zhou G, Schoenfelt KQ, Becker KM, Hoffman A, Chang YF, Blank A, Reardon CA, Kenny HA, Vaisar T, Lengyel E, Greene G, Becker L. Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis. Cell. PMID 33964209 DOI: 10.1016/j.cell.2021.04.016 |
0.396 |
|
| 2019 |
Hart PC, Kenny HA, Grassl N, Watters KM, Litchfield LM, Coscia F, Blaženović I, Ploetzky L, Fiehn O, Mann M, Lengyel E, Romero IL. Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk. Cell Reports. 29: 4086-4098.e6. PMID 31851935 DOI: 10.1016/J.Celrep.2019.11.079 |
0.454 |
|
| 2019 |
Kenny HA, Lal-Nag M, Shen M, Kara B, Nahotko DA, Wroblewski K, Fazal S, Chen S, Chiang CY, Chen YJ, Brimacombe KR, Marugan J, Ferrer M, Lengyel E. Quantitative high-throughput screening using an organotypic model identifies compounds that inhibit ovarian cancer metastasis. Molecular Cancer Therapeutics. PMID 31562255 DOI: 10.1158/1535-7163.Mct-19-0052 |
0.415 |
|
| 2019 |
McGuire S, Kara B, Hart PC, Montag A, Wroblewski K, Fazal S, Huang XY, Lengyel E, Kenny HA. Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis. Gynecologic Oncology. PMID 30797592 DOI: 10.1016/J.Ygyno.2019.01.020 |
0.472 |
|
| 2019 |
Kenny HA, Lal M, Shen M, Nahotko D, Fazal S, Chen S, Chiang C, Kara B, Yamada SD, Brimacombe K, Marugan J, Ferrer M, Lengyel E. Abstract NT-097: QUANTITATIVE HIGH-THROUGHPUT SCREENING USING AN ORGANOTYPIC MODEL IDENTIFIES TWO KINASE INHIBITORS THAT INHIBIT OVARIAN CANCER METASTASIS Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Nt-097 |
0.464 |
|
| 2019 |
Lazo I, Mukherjee A, Kenny H, Fan S, Blaženović I, Fiehn O, Lengyel E. Profiling the metabolomic composition of the ovarian cancer secretome and ovarian cancer-induced metabolomic changes in mesothelial cells Gynecologic Oncology. 154: 37. DOI: 10.1016/J.Ygyno.2019.04.088 |
0.466 |
|
| 2018 |
Lee W, Ko SY, Mohamed MS, Kenny HA, Lengyel E, Naora H. Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum. The Journal of Experimental Medicine. PMID 30567719 DOI: 10.1084/Jem.20181170 |
0.504 |
|
| 2018 |
Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, et al. Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metabolism. PMID 30174305 DOI: 10.1016/J.Cmet.2018.08.007 |
0.521 |
|
| 2018 |
Watters KM, Bajwa P, Kenny HA. Organotypic 3D Models of the Ovarian Cancer Tumor Microenvironment. Cancers. 10. PMID 30096959 DOI: 10.3390/Cancers10080265 |
0.484 |
|
| 2018 |
Ladanyi A, Mukherjee A, Kenny HA, Johnson A, Mitra AK, Sundaresan S, Nieman KM, Pascual G, Benitah SA, Montag A, Yamada SD, Abumrad NA, Lengyel E. Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis. Oncogene. PMID 29398710 DOI: 10.1038/S41388-017-0093-Z |
0.362 |
|
| 2017 |
Lal-Nag M, McGee L, Guha R, Lengyel E, Kenny HA, Ferrer M. A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth. Slas Discovery. 2472555216687082. PMID 28346091 DOI: 10.1177/2472555216687082 |
0.419 |
|
| 2017 |
Mukherjee A, Kenny HA, Lengyel E. Unsaturated Fatty Acids Maintain Cancer Cell Stemness. Cell Stem Cell. 20: 291-292. PMID 28257705 DOI: 10.1016/J.Stem.2017.02.008 |
0.38 |
|
| 2016 |
Zhang Y, Sriraman SK, Kenny HA, Luther E, Torchilin V, Lengyel E. Reversal of chemoresistance in ovarian cancer by co-delivery of a P-glycoprotein inhibitor and paclitaxel in a liposomal platform. Molecular Cancer Therapeutics. PMID 27466355 DOI: 10.1158/1535-7163.Mct-15-0986 |
0.33 |
|
| 2015 |
Peters PN, Schryver EM, Lengyel E, Kenny H. Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity. Journal of Visualized Experiments : Jove. e53541. PMID 26780294 DOI: 10.3791/53541 |
0.533 |
|
| 2015 |
Romero IL, Mukherjee A, Kenny HA, Litchfield LM, Lengyel E. Molecular pathways: trafficking of metabolic resources in the tumor microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 680-6. PMID 25691772 DOI: 10.1158/1078-0432.Ccr-14-2198 |
0.447 |
|
| 2015 |
Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer M, Lengyel E. Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy. Nature Communications. 6: 6220. PMID 25653139 DOI: 10.1038/Ncomms7220 |
0.416 |
|
| 2015 |
Zhang Y, Swindell EP, Hankins PL, Kenny HA, O'Halloran TV, Mazar AP, Lengyel E. Abstract POSTER-THER-1440: Targeted delivery of doxorubicin loaded nanobins to ovarian cancer cells through the urokinase plasminogen activator system Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Ther-1440 |
0.477 |
|
| 2014 |
Kenny HA, Chiang CY, White EA, Schryver EM, Habis M, Romero IL, Ladanyi A, Penicka CV, George J, Matlin K, Montag A, Wroblewski K, Yamada SD, Mazar AP, Bowtell D, et al. Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion. The Journal of Clinical Investigation. 124: 4614-28. PMID 25202979 DOI: 10.1172/Jci74778 |
0.519 |
|
| 2014 |
White EA, Kenny HA, Lengyel E. Three-dimensional modeling of ovarian cancer. Advanced Drug Delivery Reviews. 79: 184-92. PMID 25034878 DOI: 10.1016/J.Addr.2014.07.003 |
0.479 |
|
| 2014 |
Lengyel E, Burdette JE, Kenny HA, Matei D, Pilrose J, Haluska P, Nephew KP, Hales DB, Stack MS. Epithelial ovarian cancer experimental models. Oncogene. 33: 3619-33. PMID 23934194 DOI: 10.1038/Onc.2013.321 |
0.425 |
|
| 2013 |
Zhang Y, Kenny HA, Swindell EP, Mitra AK, Hankins PL, Ahn RW, Gwin K, Mazar AP, O'Halloran TV, Lengyel E. Urokinase plasminogen activator system-targeted delivery of nanobins as a novel ovarian cancer therapy. Molecular Cancer Therapeutics. 12: 2628-39. PMID 24061648 DOI: 10.1158/1535-7163.Mct-13-0204 |
0.497 |
|
| 2013 |
Ladanyi A, Nieman K, Penicka C, Mitra A, Kenny H, Gwin K, Wolsky R, Yamada SD, Lengyel E. Abstract 1870: Omental adipocytes promote overexpression of CD36 in ovarian cancer cells and enhance tumorigenicity. Cancer Research. 73: 1870-1870. DOI: 10.1158/1538-7445.Am2013-1870 |
0.427 |
|
| 2013 |
Kenny HA, Chiang C, Ladanyi A, George J, Bowtell DD, Gwin K, Mazar A, Lengyel E. Abstract PR11: Ovarian cancer cells activate the mesothelium in the peritoneal microenvironment promoting fibronectin production and the early steps of metastasis Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-Pr11 |
0.548 |
|
| 2012 |
Kenny HA, Nieman KM, Penicka C, Leonhardt P, Ladanyi A, Mazar AP, Gwin K, Lengyel E. Abstract 5185: Ovarian cancer cells induce fibronectin production in the peritoneal microenvironment through a TGFβRI-dependent mechanism which promotes the early steps of metastasis Cancer Research. 72: 5185-5185. DOI: 10.1158/1538-7445.Am2012-5185 |
0.544 |
|
| 2012 |
Zhang Y, Swindell EP, Ahn RW, Mitra A, Mazar AP, O'Halloran TV, Kenny HA, Lengyel E. Abstract 2885: Urokinase plasminogen activator system targeted delivery of arsenic trioxide loaded nanobins as a novel ovarian cancer therapeutic Cancer Research. 72: 2885-2885. DOI: 10.1158/1538-7445.Am2012-2885 |
0.495 |
|
| 2011 |
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nature Medicine. 17: 1498-503. PMID 22037646 DOI: 10.1038/Nm.2492 |
0.515 |
|
| 2011 |
Kenny HA, Nieman KM, Mitra AK, Lengyel E. The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer. Cancer Discovery. 1: 100-2. PMID 22013555 DOI: 10.1158/2159-8290.Cd-11-0117 |
0.407 |
|
| 2011 |
Kenny HA, Leonhardt P, Ladanyi A, Yamada SD, Montag A, Im HK, Jagadeeswaran S, Shaw DE, Mazar AP, Lengyel E. Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis Clinical Cancer Research. 17: 459-471. PMID 21149615 DOI: 10.1158/1078-0432.Ccr-10-2258 |
0.407 |
|
| 2010 |
Kenny HA, Leonhardt P, Ladanyi A, Gwin K, Lengyel E. Abstract 2331: One of the first steps of metastasis is remodeling of the extracellular matrix microenvironment Cancer Research. 70: 2331-2331. DOI: 10.1158/1538-7445.Am10-2331 |
0.485 |
|
| 2009 |
Kaur S, Kenny HA, Jagadeeswaran S, Zillhardt MR, Montag AG, Kistner E, Yamada SD, Mitra AK, Lengyel E. {beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer. The American Journal of Pathology. 175: 2184-96. PMID 19808644 DOI: 10.2353/Ajpath.2009.090028 |
0.45 |
|
| 2009 |
Kenny HA, Dogan S, Zillhardt M, K Mitra A, Yamada SD, Krausz T, Lengyel E. Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis. Cancer Treatment and Research. 149: 335-51. PMID 19763444 DOI: 10.1007/978-0-387-98094-2_16 |
0.408 |
|
| 2009 |
Kenny HA, Lengyel E. MMP-2 functions as an early response protein in ovarian cancer metastasis. Cell Cycle (Georgetown, Tex.). 8: 683-8. PMID 19221481 DOI: 10.4161/Cc.8.5.7703 |
0.466 |
|
| 2008 |
Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E. Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target. Cancer Research. 68: 2329-39. PMID 18381440 DOI: 10.1158/0008-5472.Can-07-5167 |
0.467 |
|
| 2008 |
Kenny HA, Kaur S, Coussens LM, Lengyel E. The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin. The Journal of Clinical Investigation. 118: 1367-79. PMID 18340378 DOI: 10.1172/Jci33775 |
0.437 |
|
| 2008 |
Radjabi AR, Sawada K, Jagadeeswaran S, Eichbichler A, Kenny HA, Montag A, Bruno K, Lengyel E. Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface. The Journal of Biological Chemistry. 283: 2822-34. PMID 18048360 DOI: 10.1074/Jbc.M704855200 |
0.391 |
|
| 2007 |
Kenny HA, Krausz T, Yamada SD, Lengyel E. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. International Journal of Cancer. 121: 1463-72. PMID 17546601 DOI: 10.1002/Ijc.22874 |
0.539 |
|
| 2007 |
Sawada K, Radjabi AR, Shinomiya N, Kistner E, Kenny H, Becker AR, Turkyilmaz MA, Salgia R, Yamada SD, Vande Woude GF, Tretiakova MS, Lengyel E. c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion. Cancer Research. 67: 1670-9. PMID 17308108 DOI: 10.1158/0008-5472.Can-06-1147 |
0.444 |
|
| 2006 |
Kenny HA, Woodruff TK. Follicle size class contributes to distinct secretion patterns of inhibin isoforms during the rat estrous cycle. Endocrinology. 147: 51-60. PMID 16195413 DOI: 10.1210/En.2005-0242 |
0.497 |
|
| 2004 |
Tomic D, Miller KP, Kenny HA, Woodruff TK, Hoyer P, Flaws JA. Ovarian follicle development requires Smad3. Molecular Endocrinology (Baltimore, Md.). 18: 2224-40. PMID 15192076 DOI: 10.1210/Me.2003-0414 |
0.514 |
|
| 2003 |
Chapman SC, Kenny HA, Woodruff TK. Activin, Inhibin, and Follistatin in Ovarian Physiology The Ovary: Second Edition. 273-287. DOI: 10.1016/B978-012444562-8/50017-3 |
0.411 |
|
| 2002 |
Kenny HA, Bernard DJ, Horton TH, Woodruff TK. Photoperiod-dependent regulation of inhibin in Siberian hamsters: II. Regulation of inhibin production and secretion by pregnant mare serum gonadotropin. The Journal of Endocrinology. 174: 85-94. PMID 12098666 DOI: 10.1677/Joe.0.1740085 |
0.464 |
|
| 2002 |
Kenny HA, Bernard DJ, Horton TH, Woodruff TK. Photoperiod-dependent regulation of inhibin in Siberian hamsters: I. Ovarian inhibin production and secretion. The Journal of Endocrinology. 174: 71-83. PMID 12098665 DOI: 10.1677/Joe.0.1740071 |
0.477 |
|
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