Nancy P. Keller - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Plant Pathology Agriculture, Microbiology Biology

247 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ayon NJ, Earp CE, Gupta R, Butun FA, Clements AE, Lee AG, Dainko D, Robey MT, Khin M, Mardiana L, Longcake A, Rangel-Grimaldo M, Hall MJ, Probert MR, Burdette JE, ... Keller NP, et al. Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster. Metabolomics : Official Journal of the Metabolomic Society. 20: 90. PMID 39095664 DOI: 10.1007/s11306-024-02153-8  0.326
2024 Seo HW, Wassano NS, Amir Rawa MS, Nickles GR, Damasio A, Keller NP. A Timeline of Biosynthetic Gene Cluster Discovery in : From Characterization to Future Perspectives. Journal of Fungi (Basel, Switzerland). 10. PMID 38667937 DOI: 10.3390/jof10040266  0.355
2023 Nadig N, Park SC, Bok JW, Keller NP. Conserved copper regulation of the antimicrobial isocyanide brassicicolin A in Alternaria brassicicola. Fungal Genetics and Biology : Fg & B. 169: 103839. PMID 37709127 DOI: 10.1016/j.fgb.2023.103839  0.343
2023 Karahoda B, Pfannenstiel BT, Sarikaya-Bayram Ö, Dong Z, Ho Wong K, Fleming AB, Keller NP, Bayram Ö. The KdmB-EcoA-RpdA-SntB (KERS) chromatin regulatory complex controls development, secondary metabolism and pathogenicity in Aspergillus flavus. Fungal Genetics and Biology : Fg & B. 169: 103836. PMID 37666447 DOI: 10.1016/j.fgb.2023.103836  0.335
2023 Tannous J, Labbé J, Keller NP. Identifying Fungal Secondary Metabolites and Their Role in Plant Pathogenesis. Methods in Molecular Biology (Clifton, N.J.). 2659: 193-218. PMID 37249895 DOI: 10.1007/978-1-0716-3159-1_15  0.301
2023 Liu X, Wang L, Choera T, Fang X, Wang G, Chen W, Lee YW, Mohamed SR, Dawood DH, Shi J, Xu J, Keller NP. Paralogous FgIDO genes with differential roles in tryptophan catabolism, fungal development and virulence in Fusarium graminearum. Microbiological Research. 272: 127382. PMID 37030080 DOI: 10.1016/j.micres.2023.127382  0.358
2023 Moon H, Lee MK, Bok I, Bok JW, Keller NP, Yu JH. Unraveling the Gene Regulatory Networks of the Global Regulators VeA and LaeA in Aspergillus nidulans. Microbiology Spectrum. 11: e0016623. PMID 36920196 DOI: 10.1128/spectrum.00166-23  0.31
2023 Caesar LK, Butun FA, Robey MT, Ayon NJ, Gupta R, Dainko D, Bok JW, Nickles G, Stankey RJ, Johnson D, Mead D, Cank KB, Earp CE, Raja HA, Oberlies NH, ... Keller NP, et al. Correlative metabologenomics of 110 fungi reveals metabolite-gene cluster pairs. Nature Chemical Biology. PMID 36879060 DOI: 10.1038/s41589-023-01276-8  0.307
2022 Rush TA, Tannous J, Lane MJ, Gopalakrishnan Meena M, Carrell AA, Golan JJ, Drott MT, Cottaz S, Fort S, Ané JM, Keller NP, Pelletier DA, Jacobson DA, Kainer D, Abraham PE, et al. Lipo-Chitooligosaccharides Induce Specialized Fungal Metabolite Profiles That Modulate Bacterial Growth. Msystems. e0105222. PMID 36453934 DOI: 10.1128/msystems.01052-22  0.351
2022 Luciano-Rosario D, Eagan JL, Aryal N, Dominguez EG, Hull CM, Keller NP. The Hydrophobin Gene Family Confers a Fitness Trade-off between Spore Dispersal and Host Colonization in Penicillium expansum. Mbio. e0275422. PMID 36374077 DOI: 10.1128/mbio.02754-22  0.319
2022 Yuan B, Keller NP, Oakley BR, Stajich JE, Wang CCC. Manipulation of the Global Regulator Upregulates Secondary Metabolite Production in Using CRISPR-Cas9 with In Vitro Assembled Ribonucleoproteins. Acs Chemical Biology. PMID 36197945 DOI: 10.1021/acschembio.2c00456  0.349
2022 James SW, Palmer J, Keller NP, Brown ML, Dunworth MR, Francisco SG, Watson KG, Titchen B, Achimovich A, Mahoney A, Artemiou JP, Buettner KG, Class M, Sydenstricker AL, Anglin SL. A reciprocal translocation involving Aspergillus nidulans snxAHrb1/Gbp2 and gyfA uncovers a new regulator of the G2-M transition and reveals a role in transcriptional repression for the setBSet2 histone H3-lysine-36 methyltransferase. Genetics. PMID 36005881 DOI: 10.1093/genetics/iyac130  0.526
2022 Won TH, Bok JW, Nadig N, Venkatesh N, Nickles G, Greco C, Lim FY, González JB, Turgeon BG, Keller NP, Schroeder FC. Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi. Nature Communications. 13: 4828. PMID 35973982 DOI: 10.1038/s41467-022-32394-x  0.325
2022 Yang K, Tian J, Keller NP. Post-translational modifications drive secondary metabolite biosynthesis in Aspergillus: a review. Environmental Microbiology. PMID 35645150 DOI: 10.1111/1462-2920.16034  0.348
2022 Wang G, Ran H, Fan J, Keller NP, Liu Z, Wu F, Yin WB. Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein. Science Advances. 8: eabo6094. PMID 35476435 DOI: 10.1126/sciadv.abo6094  0.338
2021 Wang W, Yu Y, Keller NP, Wang P. Presence, Mode of Action, and Application of Pathway Specific Transcription Factors in Biosynthetic Gene Clusters. International Journal of Molecular Sciences. 22. PMID 34445420 DOI: 10.3390/ijms22168709  0.351
2021 Palmer JM, Wiemann P, Greco C, Chiang YM, Wang CCC, Lindner DL, Keller NP. The sexual spore pigment asperthecin is required for normal ascospore production and protection from UV light in Aspergillus nidulans. Journal of Industrial Microbiology & Biotechnology. PMID 34415047 DOI: 10.1093/jimb/kuab055  0.691
2021 Wang W, Drott M, Greco C, Luciano-Rosario D, Wang P, Keller NP. Transcription Factor Repurposing Offers Insights into Evolution of Biosynthetic Gene Cluster Regulation. Mbio. e0139921. PMID 34281384 DOI: 10.1128/mBio.01399-21  0.346
2021 Swift CL, Louie KB, Bowen BP, Olson HM, Purvine SO, Salamov A, Mondo SJ, Solomon KV, Wright AT, Northen TR, Grigoriev IV, Keller NP, O'Malley MA. Anaerobic gut fungi are an untapped reservoir of natural products. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33906945 DOI: 10.1073/pnas.2019855118  0.307
2021 Zelante T, Choera T, Beauvais A, Fallarino F, Paolicelli G, Pieraccini G, Pieroni M, Galosi C, Beato C, De Luca A, Boscaro F, Romoli R, Liu X, Warris A, Verweij PE, ... ... Keller NP, et al. Aspergillus fumigatus tryptophan metabolic route differently affects host immunity. Cell Reports. 34: 108673. PMID 33503414 DOI: 10.1016/j.celrep.2020.108673  0.305
2020 Caesar LK, Kelleher NL, Keller NP. In the fungus where it happens: History and future propelling Aspergillus nidulans as the archetype of natural products research. Fungal Genetics and Biology : Fg & B. 144: 103477. PMID 33035657 DOI: 10.1016/j.fgb.2020.103477  0.326
2020 Caesar LK, Robey MT, Swyers M, Islam MN, Ye R, Vagadia PP, Schiltz GE, Thomas PM, Wu CC, Kelleher NL, Keller NP, Bok JW. Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds. Mbio. 11. PMID 32843555 DOI: 10.1128/Mbio.01691-20  0.427
2020 Chen L, Qu S, Yang K, Liu M, Li YX, Keller NP, Zeng X, Tian J. Perillaldehyde: a promising antifungal agent to treat oropharyngeal candidiasis. Biochemical Pharmacology. 114201. PMID 32822688 DOI: 10.1016/J.Bcp.2020.114201  0.329
2020 Rush TA, Puech-Pagès V, Bascaules A, Jargeat P, Maillet F, Haouy A, Maës AQ, Carriel CC, Khokhani D, Keller-Pearson M, Tannous J, Cope KR, Garcia K, Maeda J, Johnson C, ... ... Keller NP, et al. Lipo-chitooligosaccharides as regulatory signals of fungal growth and development. Nature Communications. 11: 3897. PMID 32753587 DOI: 10.1038/S41467-020-17615-5  0.373
2020 Acerbi E, Hortova-Kohoutkova M, Choera T, Keller N, Fric J, Stella F, Romani L, Zelante T. Modeling Approaches Reveal New Regulatory Networks in Metabolism. Journal of Fungi (Basel, Switzerland). 6. PMID 32674323 DOI: 10.3390/Jof6030108  0.34
2020 Drott MT, Satterlee TR, Skerker JM, Pfannenstiel BT, Glass NL, Keller NP, Milgroom MG. The Frequency of Sex: Population Genomics Reveals Differences in Recombination and Population Structure of the Aflatoxin-Producing Fungus Aspergillus flavus. Mbio. 11. PMID 32665272 DOI: 10.1128/Mbio.00963-20  0.311
2020 Tannous J, Barda O, Luciano-Rosario D, Prusky DB, Sionov E, Keller NP. New Insight Into Pathogenicity and Secondary Metabolism of the Plant Pathogen Through Deletion of the Epigenetic Reader SntB. Frontiers in Microbiology. 11: 610. PMID 32328048 DOI: 10.3389/Fmicb.2020.00610  0.46
2020 Costantini C, Bellet MM, Renga G, Stincardini C, Borghi M, Pariano M, Cellini B, Keller N, Romani L, Zelante T. Tryptophan Co-Metabolism at the Host-Pathogen Interface. Frontiers in Immunology. 11: 67. PMID 32082324 DOI: 10.3389/Fimmu.2020.00067  0.312
2020 Blachowicz A, Raffa N, Bok JW, Choera T, Knox B, Lim FY, Huttenlocher A, Wang CCC, Venkateswaran K, Keller NP. Contributions of Spore Secondary Metabolites to UV-C Protection and Virulence Vary in Different Aspergillus fumigatus Strains. Mbio. 11. PMID 32071276 DOI: 10.1128/Mbio.03415-19  0.348
2020 Frawley D, Greco C, Oakley B, Alhussain MM, Fleming AB, Keller NP, Bayram Ö. The tetrameric pheromone module SteC-MkkB-MpkB-SteD regulates asexual sporulation, sclerotia formation and aflatoxin production in Aspergillus flavus. Cellular Microbiology. PMID 32068947 DOI: 10.1111/Cmi.13192  0.41
2019 Jurick WM, Peng H, Beard HS, Garrett WM, Lichtner FJ, Luciano-Rosario D, Macarisin O, Liu Y, Peter KA, Gaskins VL, Yang T, Mowery J, Bauchan G, Keller N, Cooper B. Blistering1 modulates virulence via vesicle-mediated protein secretion. Molecular & Cellular Proteomics : McP. PMID 31871254 DOI: 10.1074/Mcp.Ra119.001831  0.342
2019 Rosowski EE, He J, Huisken J, Keller NP, Huttenlocher A. Efficacy of voriconazole against infection depends on host immune function. Antimicrobial Agents and Chemotherapy. PMID 31740552 DOI: 10.1128/Aac.00917-19  0.3
2019 Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A. Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish. Journal of Cell Science. PMID 31722976 DOI: 10.1242/Jcs.236539  0.334
2019 Schroeder FC, Baccile J, Le H, Pfannenstiel B, Bok JW, Gomez C, Brandenburger E, Hoffmeister D, Keller N. Diketopiperazine Formation in Fungi requires Dedicated Cyclization and Thiolation Domains. Angewandte Chemie (International Ed. in English). PMID 31342608 DOI: 10.1002/Anie.201909052  0.318
2019 Greco C, Pfannenstiel BT, Liu JC, Keller NP. Depsipeptide Aspergillicins Revealed by Chromatin Reader Protein Deletion. Acs Chemical Biology. PMID 31117395 DOI: 10.1021/Acschembio.9B00161  0.353
2019 Greco C, Keller NP, Rokas A. Unearthing fungal chemodiversity and prospects for drug discovery. Current Opinion in Microbiology. 51: 22-29. PMID 31071615 DOI: 10.1016/J.Mib.2019.03.002  0.417
2019 Lyu HN, Liu HW, Keller NP, Yin WB. Harnessing diverse transcriptional regulators for natural product discovery in fungi. Natural Product Reports. PMID 31033969 DOI: 10.1039/C8Np00027A  0.444
2019 Mueller KD, Zhang H, Serrano CR, Billmyre RB, Huh EY, Wiemann P, Keller NP, Wang Y, Heitman J, Lee SC. Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model. Journal of Microbiology (Seoul, Korea). PMID 31012059 DOI: 10.1007/S12275-019-8682-X  0.358
2019 Lan H, Wu L, Sun R, Keller NP, Yang K, Ye L, He S, Zhang F, Wang S. The HosA histone deacetylase regulates aflatoxin biosynthesis through direct regulation of aflatoxin cluster genes. Molecular Plant-Microbe Interactions : Mpmi. PMID 30986121 DOI: 10.1094/Mpmi-01-19-0033-R  0.441
2019 Ma K, Zhang P, Tao Q, Keller NP, Yang Y, Yin WB, Liu H. Characterization and Biosynthesis of a Rare Fungal Hopane-Type Triterpenoid Glycoside Involved in the Antistress Property of Aspergillus fumigatus. Organic Letters. PMID 30977375 DOI: 10.1021/Acs.Orglett.9B00984  0.362
2019 Raffa N, Keller NP. A call to arms: Mustering secondary metabolites for success and survival of an opportunistic pathogen. Plos Pathogens. 15: e1007606. PMID 30947302 DOI: 10.1371/Journal.Ppat.1007606  0.415
2019 Venkatesh N, Keller NP. Mycotoxins in Conversation With Bacteria and Fungi. Frontiers in Microbiology. 10: 403. PMID 30941105 DOI: 10.3389/Fmicb.2019.00403  0.322
2019 Niu M, Keller NP. Co-opting oxylipin signals in microbial disease. Cellular Microbiology. e13025. PMID 30866138 DOI: 10.1111/Cmi.13025  0.34
2019 Pfannenstiel BT, Keller NP. On top of biosynthetic gene clusters: How epigenetic machinery influences secondary metabolism in fungi. Biotechnology Advances. PMID 30738111 DOI: 10.1016/J.Biotechadv.2019.02.001  0.442
2019 Hodges RL, Kelkar HS, Xuei X, Skatrud PL, Keller NP, Adams TH, Kaiser RE, Vinci VA, McGilvray D. Characterization of an echinocandin B-producing strain blocked for sterigmatocystin biosynthesis reveals a translocation in the stcW gene of the aflatoxin biosynthetic pathway. Journal of Industrial Microbiology & Biotechnology. 25: 333-341. PMID 11320421 DOI: 10.1038/Sj.Jim.7000076  0.383
2018 Dindo M, Costanzi E, Pieroni M, Costantini C, Annunziato G, Bruno A, Keller NP, Romani L, Zelante T, Cellini B. Biochemical Characterization of AroH, a Putative Aromatic Amino Acid Aminotransferase. Frontiers in Molecular Biosciences. 5: 104. PMID 30547035 DOI: 10.3389/Fmolb.2018.00104  0.388
2018 Keller NP. Fungal secondary metabolism: regulation, function and drug discovery. Nature Reviews. Microbiology. PMID 30531948 DOI: 10.1038/S41579-018-0121-1  0.433
2018 Guruceaga X, Ezpeleta G, Mayayo E, Sueiro-Olivares M, Abad-Diaz-de-Cerio A, Aguirre JM, Liu HG, Wiemann P, Bok JW, Filler SG, Keller NP, Hernando FL, Ramirez-Garcia A, Rementeria A. A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus. Virulence. PMID 30251593 DOI: 10.1080/21505594.2018.1526528  0.346
2018 Pfannenstiel BT, Greco C, Sukowaty AT, Keller NP. The epigenetic reader SntB regulates secondary metabolism, development and global histone modifications in Aspergillus flavus. Fungal Genetics and Biology : Fg & B. PMID 30130575 DOI: 10.1016/J.Fgb.2018.08.004  0.433
2018 Kumar D, Tannous J, Sionov E, Keller N, Prusky D. Apple Intrinsic Factors Modulating the Global Regulator, LaeA, the Patulin Gene Cluster and Patulin Accumulation During Fruit Colonization by . Frontiers in Plant Science. 9: 1094. PMID 30100914 DOI: 10.3389/Fpls.2018.01094  0.408
2018 Rosowski EE, Raffa N, Knox BP, Golenberg N, Keller NP, Huttenlocher A. Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing. Plos Pathogens. 14: e1007229. PMID 30071103 DOI: 10.1371/Journal.Ppat.1007229  0.333
2018 Tannous J, Kumar D, Sela N, Sionov E, Prusky D, Keller NP. Fungal attack and host defense pathways unveiled in near avirulent interactions of Penicillium expansum creA mutants on apples. Molecular Plant Pathology. PMID 30047230 DOI: 10.1111/Mpp.12734  0.457
2018 Zhao X, Zhi QQ, Li JY, Keller NP, He ZM. The Antioxidant Gallic Acid Inhibits Aflatoxin Formation in by Modulating Transcription Factors FarB and CreA. Toxins. 10. PMID 29970790 DOI: 10.3390/Toxins10070270  0.359
2018 Jain S, Wiemann P, Thill E, Williams B, Keller NP, Kabbage M. A Bcl-2 Associated Athanogene () Modulates Sexual Development and Secondary Metabolism in the Filamentous Fungus . Frontiers in Microbiology. 9: 1316. PMID 29963036 DOI: 10.3389/Fmicb.2018.01316  0.39
2018 Lin H, Lyu H, Zhou S, Yu J, Keller NP, Chen L, Yin WB. Deletion of a global regulator LaeB leads to the discovery of novel polyketides in Aspergillus nidulans. Organic & Biomolecular Chemistry. PMID 29947411 DOI: 10.1039/C8Ob01326H  0.385
2018 Lim FY, Won TH, Raffa N, Baccile JA, Wisecaver J, Rokas A, Schroeder FC, Keller NP. Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus. Mbio. 9. PMID 29844112 DOI: 10.1128/Mbio.00785-18  0.415
2018 Spraker JE, Wiemann P, Baccile JA, Venkatesh N, Schumacher J, Schroeder FC, Sanchez LM, Keller NP. Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi. Mbio. 9. PMID 29789359 DOI: 10.1128/Mbio.00820-18  0.465
2018 Jain S, Sekonyela R, Knox B, Palmer JM, Huttenlocher A, Kabbage M, Keller NP. Selenate sensitivity of a laeA mutant is restored by overexpression of the bZIP protein MetR in Aspergillus fumigatus. Fungal Genetics and Biology : Fg & B. PMID 29753128 DOI: 10.1016/J.Fgb.2018.05.001  0.631
2018 Molnár ÁP, Németh Z, Fekete E, Flipphi M, Keller NP, Karaffa L. Analysis of the Relationship between Alternative Respiration and Sterigmatocystin Formation in . Toxins. 10. PMID 29677138 DOI: 10.3390/Toxins10040168  0.38
2018 Robey MT, Ye R, Bok JW, Clevenger KD, Islam MN, Chen C, Gupta R, Swyers M, Wu E, Gao P, Thomas PM, Wu CC, Keller NP, Kelleher NL. Identification of the First Diketomorpholine Biosynthetic Pathway Using FAC-MS Technology. Acs Chemical Biology. PMID 29631395 DOI: 10.1021/Acschembio.8B00024  0.384
2018 Lind AL, Lim FY, Soukup AA, Keller NP, Rokas A. An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen. Msphere. 3. PMID 29564395 DOI: 10.1128/mSphere.00050-18  0.769
2018 Wiemann P, Soukup AA, Folz JS, Wang PM, Noack A, Keller NP. CoIN: co-inducible nitrate expression system for secondary metabolites in. Fungal Biology and Biotechnology. 5: 6. PMID 29564145 DOI: 10.1186/s40694-018-0049-2  0.765
2018 Clevenger KD, Ye R, Bok JW, Thomas PM, Islam MN, Miley GP, Robey M, Chen C, Yang K, Swyers M, Wu E, Gao P, Wu C, Keller NP, Kelleher NL. Interrogation of Benzomalvin Biosynthesis using FAC-MS: Discovery of a Benzodiazepine Synthase Activity. Biochemistry. PMID 29533658 DOI: 10.1021/Acs.Biochem.8B00076  0.351
2017 Choera T, Zelante T, Romani L, Keller NP. A Multifaceted Role of Tryptophan Metabolism and Indoleamine 2,3-Dioxygenase Activity in Aspergillus fumigatus-Host Interactions. Frontiers in Immunology. 8: 1996. PMID 29403477 DOI: 10.3389/Fimmu.2017.01996  0.387
2017 Khalid S, Baccile JA, Spraker JE, Tannous J, Imran M, Schroeder FC, Keller NP. NRPS-derived isoquinolines and lipopetides mediate antagonism between plant pathogenic fungi and bacteria. Acs Chemical Biology. PMID 29182847 DOI: 10.1021/Acschembio.7B00731  0.455
2017 Lind AL, Wisecaver JH, Lameiras C, Wiemann P, Palmer JM, Keller NP, Rodrigues F, Goldman GH, Rokas A. Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species. Plos Biology. 15: e2003583. PMID 29149178 DOI: 10.1371/Journal.Pbio.2003583  0.601
2017 Zhao X, Spraker JE, Bok JW, Velk T, He ZM, Keller NP. A Cellular Fusion Cascade Regulated by LaeA Is Required for Sclerotial Development in Aspergillus flavus. Frontiers in Microbiology. 8: 1925. PMID 29051754 DOI: 10.3389/Fmicb.2017.01925  0.426
2017 Kumar D, Barad S, Sionov E, Keller NP, Prusky DB. Does the Host Contribute to Modulation of Mycotoxin Production by Fruit Pathogens? Toxins. 9. PMID 28895896 DOI: 10.3390/Toxins9090280  0.391
2017 Pfannenstiel BT, Zhao X, Wortman J, Wiemann P, Throckmorton K, Spraker JE, Soukup AA, Luo X, Lindner DL, Lim FY, Knox BP, Haas B, Fischer GJ, Choera T, Butchko RAE, ... ... Keller NP, et al. Revitalization of a Forward Genetic Screen Identifies Three New Regulators of Fungal Secondary Metabolism in the Genus Aspergillus. Mbio. 8. PMID 28874473 DOI: 10.1128/Mbio.01246-17  0.782
2017 Rank LA, Walsh NM, Liu R, Lim FY, Bok JW, Huang M, Keller NP, Gellman SH, Hull CM. A cationic polymer that shows high antifungal activity against diverse human pathogens. Antimicrobial Agents and Chemotherapy. PMID 28739790 DOI: 10.1128/Aac.00204-17  0.309
2017 Clevenger KD, Bok JW, Ye R, Miley GP, Verdan MH, Velk T, Chen C, Yang K, Robey MT, Gao P, Lamprecht M, Thomas PM, Islam MN, Palmer JM, Wu CC, ... Keller NP, et al. A scalable platform to identify fungal secondary metabolites and their gene clusters. Nature Chemical Biology. PMID 28604695 DOI: 10.1038/Nchembio.2408  0.615
2017 Knox BP, Huttenlocher A, Keller NP. Real-time visualization of immune cell clearance of Aspergillus fumigatus spores and hyphae. Fungal Genetics and Biology : Fg & B. PMID 28559109 DOI: 10.1016/J.Fgb.2017.05.005  0.305
2017 Fischer GJ, Bacon W, Yang J, Palmer JM, Dagenais T, Hammock BD, Keller NP. Lipoxygenase Activity Accelerates Programmed Spore Germination in Aspergillus fumigatus. Frontiers in Microbiology. 8: 831. PMID 28536571 DOI: 10.3389/Fmicb.2017.00831  0.542
2017 Zhang P, Wang X, Fan A, Zheng Y, Liu X, Wang S, Zou H, Oakley BR, Keller NP, Yin WB. A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. Molecular Microbiology. PMID 28517364 DOI: 10.1111/Mmi.13711  0.454
2017 Wiemann P, Perevitsky A, Lim FY, Shadkchan Y, Knox BP, Landero Figueora JA, Choera T, Niu M, Steinberger AJ, Wüthrich M, Idol RA, Klein BS, Dinauer MC, Huttenlocher A, Osherov N, ... Keller NP, et al. Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. Cell Reports. 19: 1008-1021. PMID 28467895 DOI: 10.1016/J.Celrep.2017.04.019  0.318
2017 Tannous J, Keller NP, Atoui A, El Khoury A, Lteif R, Oswald IP, Puel O. Secondary Metabolism in Penicillium expansum: Emphasis on Recent Advances in Patulin Research. Critical Reviews in Food Science and Nutrition. 0. PMID 28362209 DOI: 10.1080/10408398.2017.1305945  0.333
2017 Vargas-Muñiz JM, Renshaw H, Waitt G, Soderblom EJ, Moseley MA, Palmer JM, Juvvadi PR, Keller NP, Steinbach WJ. Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus. Biochemical and Biophysical Research Communications. PMID 28238781 DOI: 10.1016/J.Bbrc.2017.02.116  0.534
2017 Keller NP. Heterogeneity Confounds Establishment of "a" Model Microbial Strain. Mbio. 8. PMID 28223452 DOI: 10.1128/Mbio.00135-17  0.32
2017 Soukup AA, Fischer GJ, Luo J, Keller NP. The Aspergillus nidulans Pbp1 homolog is required for normal sexual development and secondary metabolism. Fungal Genetics and Biology : Fg & B. PMID 28089630 DOI: 10.1016/J.Fgb.2017.01.004  0.734
2016 Bignell E, Cairns TC, Throckmorton K, Nierman WC, Keller NP. Secondary metabolite arsenal of an opportunistic pathogenic fungus. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 371. PMID 28080993 DOI: 10.1098/Rstb.2016.0023  0.443
2016 Németh Z, Molnár ÁP, Fejes B, Novák L, Karaffa L, Keller NP, Fekete E. Growth-Phase Sterigmatocystin Formation on Lactose Is Mediated via Low Specific Growth Rates in Aspergillus nidulans. Toxins. 8. PMID 27916804 DOI: 10.3390/Toxins8120354  0.312
2016 Rosowski EE, Deng Q, Keller NP, Huttenlocher A. Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish. Journal of Immunology (Baltimore, Md. : 1950). PMID 27837107 DOI: 10.4049/Jimmunol.1600928  0.343
2016 Knox BP, Blachowicz A, Palmer JM, Romsdahl J, Huttenlocher A, Wang CC, Keller NP, Venkateswaran K. Characterization of Aspergillus fumigatus Isolates from Air and Surfaces of the International Space Station. Msphere. 1. PMID 27830189 DOI: 10.1128/mSphere.00227-16  0.503
2016 Luo X, Affeldt KJ, Keller NP. Characterization of the Far Transcription Factor Family in Aspergillus flavus. G3 (Bethesda, Md.). PMID 27534569 DOI: 10.1534/G3.116.032466  0.805
2016 Kumar D, Barad S, Chen Y, Luo X, Tannous J, Dubey A, Glam N, Tian S, Li B, Keller N, Prusky D. LaeA regulation of secondary metabolism modulates virulence in Penicillium expansum and is mediated by sucrose. Molecular Plant Pathology. PMID 27528575 DOI: 10.1111/Mpp.12469  0.445
2016 Drees KP, Palmer JM, Sebra R, Lorch JM, Chen C, Wu CC, Bok JW, Keller NP, Blehert DS, Cuomo CA, Lindner DL, Foster JT. Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome. Genome Announcements. 4. PMID 27365344 DOI: 10.1128/Genomea.00445-16  0.681
2016 Henke MT, Soukup AA, Goering AW, McClure RA, Thomson RJ, Keller NP, Kelleher NL. New aspercryptins, lipopeptide natural products, revealed by HDAC inhibition in Aspergillus nidulans. Acs Chemical Biology. PMID 27310134 DOI: 10.1021/Acschembio.6B00398  0.751
2016 Yeh HH, Ahuja M, Chiang YM, Oakley CE, Moore S, Yoon O, Hajovsky H, Bok JW, Keller NP, Wang CC, Oakley BR. Resistance gene-guided genome mining: Serial promoter exchanges in Aspergillus nidulans reveal the biosynthetic pathway for fellutamide B, a proteasome inhibitor. Acs Chemical Biology. PMID 27294372 DOI: 10.1021/Acschembio.6B00213  0.389
2016 Baccile JA, Spraker JE, Le HH, Brandenburger E, Gomez C, Bok JW, Macheleidt J, Brakhage AA, Hoffmeister D, Keller NP, Schroeder FC. Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. Nature Chemical Biology. PMID 27065235 DOI: 10.1038/Nchembio.2061  0.424
2016 Kerr SC, Fischer GJ, Sinha M, McCabe O, Palmer JM, Choera T, Yun Lim F, Wimmerova M, Carrington SD, Yuan S, Lowell CA, Oscarson S, Keller NP, Fahy JV. FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection. Plos Pathogens. 12: e1005555. PMID 27058347 DOI: 10.1371/Journal.Ppat.1005555  0.53
2016 Wu G, Zhou H, Zhang P, Wang X, Li W, Zhang W, Liu X, Liu HW, Keller NP, An Z, Yin WB. Polyketide Production of Pestaloficiols and Macrodiolide Ficiolides Revealed by Manipulations of Epigenetic Regulators in an Endophytic Fungus. Organic Letters. PMID 27015125 DOI: 10.1021/Acs.Orglett.6B00562  0.328
2016 Zhao Y, He M, Xi Q, Ding J, Hao B, Keller NP, Zheng W. Reversible S-nitrosylation limits over synthesis of fungal styrylpyrone upon nitric oxide burst. Applied Microbiology and Biotechnology. PMID 27000840 DOI: 10.1007/S00253-016-7442-7  0.367
2016 Spraker JE, Sanchez LM, Lowe TM, Dorrestein PC, Keller NP. Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues. The Isme Journal. PMID 26943626 DOI: 10.1038/Ismej.2016.32  0.347
2016 Fischer GJ, Keller NP. Production of cross-kingdom oxylipins by pathogenic fungi: An update on their role in development and pathogenicity. Journal of Microbiology (Seoul, Korea). 54: 254-64. PMID 26920885 DOI: 10.1007/S12275-016-5620-Z  0.394
2016 Barkal LJ, Theberge AB, Guo CJ, Spraker J, Rappert L, Berthier J, Brakke KA, Wang CC, Beebe DJ, Keller NP, Berthier E. Microbial metabolomics in open microscale platforms. Nature Communications. 7: 10610. PMID 26842393 DOI: 10.1038/Ncomms10610  0.354
2016 Soukup AA, Keller NP, Wiemann P. Enhancing Nonribosomal Peptide Biosynthesis in Filamentous Fungi. Methods in Molecular Biology (Clifton, N.J.). 1401: 149-60. PMID 26831707 DOI: 10.1007/978-1-4939-3375-4_10  0.784
2015 Guo CJ, Sun WW, Bruno KS, Oakley BR, Keller NP, Wang CCC. Spatial regulation of a common precursor from two distinct genes generates metabolite diversity. Chemical Science. 6: 5913-5921. PMID 28791090 DOI: 10.1039/C5Sc01058F  0.449
2015 Tyler BM, Kale SD, Wang Q, Tao K, Clark HR, Drews K, Antignani V, Rumore A, Hayes T, Plett JM, Fudal I, Gu B, Chen Q, Affeldt KJ, Berthier E, ... ... Keller NP, et al. Microbe-Independent Entry of Oomycete RxLR Effectors and Fungal RxLR-Like Effectors Into Plant and Animal Cells Is Specific and Reproducible. Molecular Plant-Microbe Interactions : Mpmi. 2015: 51-56. PMID 27839069 DOI: 10.1094/MPMI-99-99-0002.testissue  0.773
2015 Song J, Zhai P, Zhang Y, Zhang C, Sang H, Han G, Keller NP, Lu L. The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility. Mbio. 7. PMID 26908577 DOI: 10.1128/Mbio.01919-15  0.514
2015 Wang PM, Choera T, Wiemann P, Pisithkul T, Amador-Noguez D, Keller NP. TrpE feedback mutants reveal roadblocks and conduits toward increasing secondary metabolism in Aspergillus fumigatus. Fungal Genetics and Biology : Fg & B. PMID 26701311 DOI: 10.1016/J.Fgb.2015.12.002  0.459
2015 Throckmorton K, Wiemann P, Keller NP. Evolution of Chemical Diversity in a Group of Non-Reduced Polyketide Gene Clusters: Using Phylogenetics to Inform the Search for Novel Fungal Natural Products. Toxins. 7: 3572-607. PMID 26378577 DOI: 10.3390/Toxins7093572  0.424
2015 Keller NP. Translating biosynthetic gene clusters into fungal armor and weaponry. Nature Chemical Biology. 11: 671-7. PMID 26284674 DOI: 10.1038/Nchembio.1897  0.407
2015 Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Keller NP, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890  0.374
2015 Throckmorton K, Lim FY, Kontoyiannis DP, Zheng W, Keller NP. Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus. Environmental Microbiology. PMID 26242966 DOI: 10.1111/1462-2920.13007  0.403
2015 Bok JW, Ye R, Clevenger KD, Mead D, Wagner M, Krerowicz A, Albright JC, Goering AW, Thomas PM, Kelleher NL, Keller NP, Wu CC. Fungal artificial chromosomes for mining of the fungal secondary metabolome. Bmc Genomics. 16: 343. PMID 25925221 DOI: 10.1186/S12864-015-1561-X  0.399
2015 Wang X, Wu F, Liu L, Liu X, Che Y, Keller NP, Guo L, Yin WB. The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici. Fungal Genetics and Biology : Fg & B. PMID 25847004 DOI: 10.1016/J.Fgb.2015.03.010  0.368
2015 Albright JC, Henke MT, Soukup AA, McClure RA, Thomson RJ, Keller NP, Kelleher NL. Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation. Acs Chemical Biology. 10: 1535-41. PMID 25815712 DOI: 10.1021/Acschembio.5B00025  0.755
2015 Sarikaya-Bayram Ö, Palmer JM, Keller N, Braus GH, Bayram Ö. One Juliet and four Romeos: VeA and its methyltransferases. Frontiers in Microbiology. 6: 1. PMID 25653648 DOI: 10.3389/Fmicb.2015.00001  0.578
2015 Zhao Y, Xi Q, Xu Q, He M, Ding J, Dai Y, Keller NP, Zheng W. Correlation of nitric oxide produced by an inducible nitric oxide synthase-like protein with enhanced expression of the phenylpropanoid pathway in Inonotus obliquus cocultured with Phellinus morii. Applied Microbiology and Biotechnology. 99: 4361-72. PMID 25582560 DOI: 10.1007/S00253-014-6367-2  0.445
2015 Macheleidt J, Scherlach K, Neuwirth T, Schmidt-Heck W, Straßburger M, Spraker J, Baccile JA, Schroeder FC, Keller NP, Hertweck C, Heinekamp T, Brakhage AA. Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus. Molecular Microbiology. 96: 148-62. PMID 25582336 DOI: 10.1111/Mmi.12926  0.484
2015 Zheng H, Kim J, Liew M, Yan JK, Herrera O, Bok JW, Kelleher NL, Keller NP, Wang Y. Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus. Current Biology : Cb. 25: 29-37. PMID 25532893 DOI: 10.1016/J.Cub.2014.11.018  0.332
2014 Bok JW, Wiemann P, Garvey GS, Lim FY, Haas B, Wortman J, Keller NP. Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus. Bmc Genomics. 15: 1011. PMID 25416206 DOI: 10.1186/1471-2164-15-1011  0.328
2014 Affeldt KJ, Carrig J, Amare M, Keller NP. Global survey of canonical Aspergillus flavus G protein-coupled receptors. Mbio. 5: e01501-14. PMID 25316696 DOI: 10.1128/Mbio.01501-14  0.791
2014 Lim FY, Keller NP. Spatial and temporal control of fungal natural product synthesis. Natural Product Reports. 31: 1277-86. PMID 25142354 DOI: 10.1039/C4Np00083H  0.409
2014 Miyamoto K, Murakami T, Kakumyan P, Keller NP, Matsui K. Formation of 1-octen-3-ol from Aspergillus flavus conidia is accelerated after disruption of cells independently of Ppo oxygenases, and is not a main cause of inhibition of germination. Peerj. 2: e395. PMID 24883255 DOI: 10.7717/Peerj.395  0.335
2014 Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A. Distinct innate immune phagocyte responses to Aspergillus fumigatus conidia and hyphae in zebrafish larvae. Eukaryotic Cell. 13: 1266-77. PMID 24879123 DOI: 10.1128/Ec.00080-14  0.333
2014 Spraker JE, Jewell K, Roze LV, Scherf J, Ndagano D, Beaudry R, Linz JE, Allen C, Keller NP. A volatile relationship: profiling an inter-kingdom dialogue between two plant pathogens, Ralstonia Solanacearum and Aspergillus Flavus. Journal of Chemical Ecology. 40: 502-13. PMID 24801606 DOI: 10.1007/S10886-014-0432-2  0.344
2014 Amare MG, Keller NP. Molecular mechanisms of Aspergillus flavus secondary metabolism and development. Fungal Genetics and Biology : Fg & B. 66: 11-8. PMID 24613992 DOI: 10.1016/J.Fgb.2014.02.008  0.43
2014 Lim FY, Ames B, Walsh CT, Keller NP. Co-ordination between BrlA regulation and secretion of the oxidoreductase FmqD directs selective accumulation of fumiquinazoline C to conidial tissues in Aspergillus fumigatus. Cellular Microbiology. 16: 1267-83. PMID 24612080 DOI: 10.1111/Cmi.12284  0.796
2014 Wiemann P, Keller NP. Strategies for mining fungal natural products. Journal of Industrial Microbiology & Biotechnology. 41: 301-13. PMID 24146366 DOI: 10.1007/S10295-013-1366-3  0.41
2014 Mattupalli C, Spraker JE, Berthier E, Charkowski AO, Keller NP, Shepherd RW. A Microfluidic Assay for Identifying Differential Responses of Plant and Human Fungal Pathogens to Tobacco Phylloplanins Plant Health Progress. 15: 130-134. DOI: 10.1094/Php-Rs-14-0009  0.321
2013 Soukup A, Keller NP. Western Analysis of Histone Modifications (Aspergillus nidulans). Bio-Protocol. 3. PMID 27275003  0.687
2013 Wiemann P, Guo CJ, Palmer JM, Sekonyela R, Wang CC, Keller NP. Prototype of an intertwined secondary-metabolite supercluster. Proceedings of the National Academy of Sciences of the United States of America. 110: 17065-70. PMID 24082142 DOI: 10.1073/Pnas.1313258110  0.635
2013 Amaike S, Affeldt KJ, Yin WB, Franke S, Choithani A, Keller NP. The bZIP protein MeaB mediates virulence attributes in Aspergillus flavus. Plos One. 8: e74030. PMID 24040154 DOI: 10.1371/Journal.Pone.0074030  0.811
2013 Gauthier GM, Keller NP. Crossover fungal pathogens: the biology and pathogenesis of fungi capable of crossing kingdoms to infect plants and humans. Fungal Genetics and Biology : Fg & B. 61: 146-57. PMID 24021881 DOI: 10.1016/J.Fgb.2013.08.016  0.332
2013 Bok JW, Soukup AA, Chadwick E, Chiang YM, Wang CC, Keller NP. VeA and MvlA repression of the cryptic orsellinic acid gene cluster in Aspergillus nidulans involves histone 3 acetylation. Molecular Microbiology. 89: 963-74. PMID 23841751 DOI: 10.1111/Mmi.12326  0.766
2013 Sekonyela R, Palmer JM, Bok JW, Jain S, Berthier E, Forseth R, Schroeder F, Keller NP. RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis. Plos One. 8: e62591. PMID 23671611 DOI: 10.1371/Journal.Pone.0062591  0.57
2013 Palmer JM, Bok JW, Lee S, Dagenais TR, Andes DR, Kontoyiannis DP, Keller NP. Loss of CclA, required for histone 3 lysine 4 methylation, decreases growth but increases secondary metabolite production in Aspergillus fumigatus. Peerj. 1: e4. PMID 23638376 DOI: 10.7717/Peerj.4  0.605
2013 Berthier E, Lim FY, Deng Q, Guo CJ, Kontoyiannis DP, Wang CC, Rindy J, Beebe DJ, Huttenlocher A, Keller NP. Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites. Plos Pathogens. 9: e1003289. PMID 23592999 DOI: 10.1371/Journal.Ppat.1003289  0.407
2013 Tyler BM, Kale SD, Wang Q, Tao K, Clark HR, Drews K, Antignani V, Rumore A, Hayes T, Plett JM, Fudal I, Gu B, Chen Q, Affeldt KJ, Berthier E, ... ... Keller NP, et al. Microbe-independent entry of oomycete RxLR effectors and fungal RxLR-like effectors into plant and animal cells is specific and reproducible. Molecular Plant-Microbe Interactions : Mpmi. 26: 611-6. PMID 23550528 DOI: 10.1094/Mpmi-02-13-0051-Ia  0.782
2013 Patananan AN, Palmer JM, Garvey GS, Keller NP, Clarke SG. A novel automethylation reaction in the Aspergillus nidulans LaeA protein generates S-methylmethionine. The Journal of Biological Chemistry. 288: 14032-45. PMID 23532849 DOI: 10.1074/Jbc.M113.465765  0.594
2013 Karimi-Aghcheh R, Bok JW, Phatale PA, Smith KM, Baker SE, Lichius A, Omann M, Zeilinger S, Seiboth B, Rhee C, Keller NP, Freitag M, Kubicek CP. Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator. G3 (Bethesda, Md.). 3: 369-78. PMID 23390613 DOI: 10.1534/G3.112.005140  0.423
2013 Yin WB, Baccile JA, Bok JW, Chen Y, Keller NP, Schroeder FC. A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. Journal of the American Chemical Society. 135: 2064-7. PMID 23360537 DOI: 10.1021/Ja311145N  0.426
2013 Palmer JM, Theisen JM, Duran RM, Grayburn WS, Calvo AM, Keller NP. Secondary metabolism and development is mediated by LlmF control of VeA subcellular localization in Aspergillus nidulans. Plos Genetics. 9: e1003193. PMID 23341778 DOI: 10.1371/Journal.Pgen.1003193  0.597
2013 Forseth RR, Amaike S, Schwenk D, Affeldt KJ, Hoffmeister D, Schroeder FC, Keller NP. Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus. Angewandte Chemie (International Ed. in English). 52: 1590-4. PMID 23281040 DOI: 10.1002/Anie.201207456  0.801
2013 Yin WB, Reinke AW, Szilágyi M, Emri T, Chiang YM, Keating AE, Pócsi I, Wang CC, Keller NP. bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans. Microbiology (Reading, England). 159: 77-88. PMID 23154967 DOI: 10.1099/Mic.0.063370-0  0.384
2013 Keller N. Unlocking Cryptic Fungal Natural Product Clusters Planta Medica. 79. DOI: 10.1055/S-0033-1348488  0.349
2013 Jain S, Keller N. Insights to fungal biology through LaeA sleuthing Fungal Biology Reviews. 27: 51-59. DOI: 10.1016/J.Fbr.2013.05.004  0.416
2012 Affeldt KJ, Brodhagen M, Keller NP. Aspergillus oxylipin signaling and quorum sensing pathways depend on g protein-coupled receptors. Toxins. 4: 695-717. PMID 23105976 DOI: 10.3390/Toxins4090695  0.789
2012 Lim FY, Sanchez JF, Wang CC, Keller NP. Toward awakening cryptic secondary metabolite gene clusters in filamentous fungi. Methods in Enzymology. 517: 303-24. PMID 23084945 DOI: 10.1016/B978-0-12-404634-4.00015-2  0.39
2012 Wang S, Cao J, Liu X, Hu H, Shi J, Zhang S, Keller NP, Lu L. Putative calcium channels CchA and MidA play the important roles in conidiation, hyphal polarity and cell wall components in Aspergillus nidulans. Plos One. 7: e46564. PMID 23071589 DOI: 10.1371/Journal.Pone.0046564  0.301
2012 Bok JW, Keller NP. Fast and easy method for construction of plasmid vectors using modified quick-change mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 944: 163-74. PMID 23065615 DOI: 10.1007/978-1-62703-122-6_11  0.323
2012 Soukup AA, Farnoodian M, Berthier E, Keller NP. NosA, a transcription factor important in Aspergillus fumigatus stress and developmental response, rescues the germination defect of a laeA deletion. Fungal Genetics and Biology : Fg & B. 49: 857-65. PMID 23022264 DOI: 10.1016/J.Fgb.2012.09.005  0.766
2012 Soukup AA, Chiang YM, Bok JW, Reyes-Dominguez Y, Oakley BR, Wang CC, Strauss J, Keller NP. Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. Molecular Microbiology. 86: 314-30. PMID 22882998 DOI: 10.1111/J.1365-2958.2012.08195.X  0.769
2012 Lim FY, Hou Y, Chen Y, Oh JH, Lee I, Bugni TS, Keller NP. Genome-based cluster deletion reveals an endocrocin biosynthetic pathway in Aspergillus fumigatus. Applied and Environmental Microbiology. 78: 4117-25. PMID 22492455 DOI: 10.1128/Aem.07710-11  0.461
2012 Yin WB, Amaike S, Wohlbach DJ, Gasch AP, Chiang YM, Wang CC, Bok JW, Rohlfs M, Keller NP. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Molecular Microbiology. 83: 1024-34. PMID 22283524 DOI: 10.1111/J.1365-2958.2012.07986.X  0.811
2012 Sanchez JF, Somoza AD, Keller NP, Wang CC. Advances in Aspergillus secondary metabolite research in the post-genomic era. Natural Product Reports. 29: 351-71. PMID 22228366 DOI: 10.1039/C2Np00084A  0.333
2012 Affeldt KJ, Keller NP. Oxylipins in fungal-mammalian interactions Biocommunication of Fungi. 2147483647: 291-303. DOI: 10.1007/978-94-007-4264-2_19  0.785
2012 Forseth RR, Amaike S, Schwenk D, Affeldt KJ, Hoffmeister D, Schroeder FC, Keller NP. Homologe NRPS-ähnliche Genloci vermitteln eine redundante Naturstoff-Biosynthese inAspergillus flavus Angewandte Chemie. 125: 1632-1636. DOI: 10.1002/Ange.201207456  0.75
2011 Scherm B, Orrù M, Balmas V, Spanu F, Azara E, Delogu G, Hammond TM, Keller NP, Migheli Q. Altered trichothecene biosynthesis in TRI6-silenced transformants of Fusarium culmorum influences the severity of crown and foot rot on durum wheat seedlings. Molecular Plant Pathology. 12: 759-71. PMID 21726376 DOI: 10.1111/J.1364-3703.2011.00709.X  0.389
2011 Yin W, Keller NP. Transcriptional regulatory elements in fungal secondary metabolism. Journal of Microbiology (Seoul, Korea). 49: 329-39. PMID 21717315 DOI: 10.1007/S12275-011-1009-1  0.443
2011 Forseth RR, Fox EM, Chung D, Howlett BJ, Keller NP, Schroeder FC. Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis. Journal of the American Chemical Society. 133: 9678-81. PMID 21612254 DOI: 10.1021/Ja2029987  0.462
2011 Amaike S, Keller NP. Aspergillus flavus. Annual Review of Phytopathology. 49: 107-33. PMID 21513456 DOI: 10.1146/annurev-phyto-072910-095221  0.808
2011 Giles SS, Soukup AA, Lauer C, Shaaban M, Lin A, Oakley BR, Wang CC, Keller NP. Cryptic Aspergillus nidulans antimicrobials. Applied and Environmental Microbiology. 77: 3669-75. PMID 21478304 DOI: 10.1128/Aem.02000-10  0.774
2010 Shaaban MI, Bok JW, Lauer C, Keller NP. Suppressor mutagenesis identifies a velvet complex remediator of Aspergillus nidulans secondary metabolism. Eukaryotic Cell. 9: 1816-24. PMID 20935144 DOI: 10.1128/Ec.00189-10  0.437
2010 Palmer JM, Mallaredy S, Perry DW, Sanchez JF, Theisen JM, Szewczyk E, Oakley BR, Wang CC, Keller NP, Mirabito PM. Telomere position effect is regulated by heterochromatin-associated proteins and NkuA in Aspergillus nidulans. Microbiology (Reading, England). 156: 3522-31. PMID 20724388 DOI: 10.1099/Mic.0.039255-0  0.577
2010 Palmer JM, Keller NP. Secondary metabolism in fungi: does chromosomal location matter? Current Opinion in Microbiology. 13: 431-6. PMID 20627806 DOI: 10.1016/J.Mib.2010.04.008  0.616
2010 Wiemann P, Brown DW, Kleigrewe K, Bok JW, Keller NP, Humpf HU, Tudzynski B. FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence. Molecular Microbiology. 77: 972-94. PMID 20572938 DOI: 10.1111/J.1365-2958.2010.07263.X  0.377
2010 Georgianna DR, Fedorova ND, Burroughs JL, Dolezal AL, Bok JW, Horowitz-Brown S, Woloshuk CP, Yu J, Keller NP, Payne GA. Beyond aflatoxin: four distinct expression patterns and functional roles associated with Aspergillus flavus secondary metabolism gene clusters. Molecular Plant Pathology. 11: 213-26. PMID 20447271 DOI: 10.1111/J.1364-3703.2009.00594.X  0.665
2010 Chiang YM, Oakley BR, Keller NP, Wang CC. Unraveling polyketide synthesis in members of the genus Aspergillus. Applied Microbiology and Biotechnology. 86: 1719-36. PMID 20361326 DOI: 10.1007/S00253-010-2525-3  0.331
2010 Shaaban M, Palmer JM, El-Naggar WA, El-Sokkary MA, Habib el-SE, Keller NP. Involvement of transposon-like elements in penicillin gene cluster regulation. Fungal Genetics and Biology : Fg & B. 47: 423-32. PMID 20219692 DOI: 10.1016/J.Fgb.2010.02.006  0.603
2010 Sanchez JF, Chiang YM, Szewczyk E, Davidson AD, Ahuja M, Elizabeth Oakley C, Woo Bok J, Keller N, Oakley BR, Wang CC. Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans. Molecular Biosystems. 6: 587-93. PMID 20174687 DOI: 10.1039/B904541D  0.368
2010 Chiang YM, Szewczyk E, Davidson AD, Entwistle R, Keller NP, Wang CC, Oakley BR. Characterization of the Aspergillus nidulans monodictyphenone gene cluster. Applied and Environmental Microbiology. 76: 2067-74. PMID 20139316 DOI: 10.1128/Aem.02187-09  0.435
2010 Reyes-Dominguez Y, Bok JW, Berger H, Shwab EK, Basheer A, Gallmetzer A, Scazzocchio C, Keller N, Strauss J. Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans. Molecular Microbiology. 76: 1376-86. PMID 20132440 DOI: 10.1111/J.1365-2958.2010.07051.X  0.421
2010 Dagenais TR, Giles SS, Aimanianda V, Latgé JP, Hull CM, Keller NP. Aspergillus fumigatus LaeA-mediated phagocytosis is associated with a decreased hydrophobin layer. Infection and Immunity. 78: 823-9. PMID 19917717 DOI: 10.1128/Iai.00980-09  0.35
2010 Trienens M, Keller NP, Rohlfs M. Fruit, flies and filamentous fungi - experimental analysis of animal-microbe competition using Drosophila melanogaster and Aspergillus mould as a model system Oikos. 119: 1765-1775. DOI: 10.1111/j.1600-0706.2010.18088.x  0.322
2010 Garvey GS, Keller NP. Fungal secondary metabolites and their fundamental roles in human mycoses Current Fungal Infection Reports. 4: 256-265. DOI: 10.1007/S12281-010-0032-8  0.452
2009 Chiang YM, Lee KH, Sanchez JF, Keller NP, Wang CC. Unlocking fungal cryptic natural products. Natural Product Communications. 4: 1505-10. PMID 19967983 DOI: 10.1177/1934578X0900401113  0.415
2009 Dagenais TR, Keller NP. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clinical Microbiology Reviews. 22: 447-65. PMID 19597008 DOI: 10.1128/Cmr.00055-08  0.354
2009 Lee I, Oh JH, Shwab EK, Dagenais TR, Andes D, Keller NP. HdaA, a class 2 histone deacetylase of Aspergillus fumigatus, affects germination and secondary metabolite production. Fungal Genetics and Biology : Fg & B. 46: 782-90. PMID 19563902 DOI: 10.1016/J.Fgb.2009.06.007  0.44
2009 Brown SH, Scott JB, Bhaheetharan J, Sharpee WC, Milde L, Wilson RA, Keller NP. Oxygenase coordination is required for morphological transition and the host-fungus interaction of Aspergillus flavus. Molecular Plant-Microbe Interactions : Mpmi. 22: 882-94. PMID 19522570 DOI: 10.1094/Mpmi-22-7-0882  0.406
2009 Giles SS, Dagenais TR, Botts MR, Keller NP, Hull CM. Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infection and Immunity. 77: 3491-500. PMID 19451235 DOI: 10.1128/Iai.00334-09  0.331
2009 Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, Sanchez JF, Lo HC, Watanabe K, Strauss J, Oakley BR, Wang CC, Keller NP. Chromatin-level regulation of biosynthetic gene clusters. Nature Chemical Biology. 5: 462-4. PMID 19448638 DOI: 10.1038/Nchembio.177  0.373
2009 Amaike S, Keller NP. Distinct roles for VeA and LaeA in development and pathogenesis of Aspergillus flavus. Eukaryotic Cell. 8: 1051-60. PMID 19411623 DOI: 10.1128/Ec.00088-09  0.803
2009 Chiang YM, Szewczyk E, Davidson AD, Keller N, Oakley BR, Wang CC. A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans. Journal of the American Chemical Society. 131: 2965-70. PMID 19199437 DOI: 10.1021/Ja8088185  0.486
2009 Gao X, Brodhagen M, Isakeit T, Brown SH, Göbel C, Betran J, Feussner I, Keller NP, Kolomiets MV. Inactivation of the lipoxygenase ZmLOX3 increases susceptibility of maize to Aspergillus spp. Molecular Plant-Microbe Interactions : Mpmi. 22: 222-31. PMID 19132874 DOI: 10.1094/Mpmi-22-2-0222  0.418
2009 Bok JW, Keller NP, Tsitsigiannis DI. Real-time and semiquantitative RT-PCR methods to analyze gene expression patterns during Aspergillus-host interactions. Methods in Molecular Biology (Clifton, N.J.). 470: 151-67. PMID 19089383 DOI: 10.1007/978-1-59745-204-5_13  0.713
2008 Palmer JM, Perrin RM, Dagenais TR, Keller NP. H3K9 methylation regulates growth and development in Aspergillus fumigatus. Eukaryotic Cell. 7: 2052-60. PMID 18849468 DOI: 10.1128/Ec.00224-08  0.609
2008 Kale SP, Milde L, Trapp MK, Frisvad JC, Keller NP, Bok JW. Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus. Fungal Genetics and Biology : Fg & B. 45: 1422-9. PMID 18667168 DOI: 10.1016/J.Fgb.2008.06.009  0.456
2008 Bayram O, Krappmann S, Ni M, Bok JW, Helmstaedt K, Valerius O, Braus-Stromeyer S, Kwon NJ, Keller NP, Yu JH, Braus GH. VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science (New York, N.Y.). 320: 1504-6. PMID 18556559 DOI: 10.1126/Science.1155888  0.346
2008 Dagenais TR, Chung D, Giles SS, Hull CM, Andes D, Keller NP. Defects in conidiophore development and conidium-macrophage interactions in a dioxygenase mutant of Aspergillus fumigatus. Infection and Immunity. 76: 3214-20. PMID 18443090 DOI: 10.1128/Iai.00009-08  0.388
2008 Stadler M, Keller NP. Paradigm shifts in fungal secondary metabolite research. Mycological Research. 112: 127-30. PMID 18319144 DOI: 10.1016/J.Mycres.2007.12.002  0.399
2008 Shwab EK, Keller NP. Regulation of secondary metabolite production in filamentous ascomycetes. Mycological Research. 112: 225-30. PMID 18280128 DOI: 10.1016/J.Mycres.2007.08.021  0.372
2008 Brodhagen M, Tsitsigiannis DI, Hornung E, Goebel C, Feussner I, Keller NP. Reciprocal oxylipin-mediated cross-talk in the Aspergillus-seed pathosystem. Molecular Microbiology. 67: 378-91. PMID 18181962 DOI: 10.1111/J.1365-2958.2007.06045.X  0.754
2008 Hammond TM, Bok JW, Andrewski MD, Reyes-Domínguez Y, Scazzocchio C, Keller NP. RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans. Eukaryotic Cell. 7: 339-49. PMID 18065653 DOI: 10.1128/Ec.00355-07  0.316
2008 Fox EM, Gardiner DM, Keller NP, Howlett BJ. A Zn(II)2Cys6 DNA binding protein regulates the sirodesmin PL biosynthetic gene cluster in Leptosphaeria maculans. Fungal Genetics and Biology : Fg & B. 45: 671-82. PMID 18023597 DOI: 10.1016/J.Fgb.2007.10.005  0.389
2008 Maggio-Hall LA, Lyne P, Wolff JA, Keller NP. A single acyl-CoA dehydrogenase is required for catabolism of isoleucine, valine and short-chain fatty acids in Aspergillus nidulans. Fungal Genetics and Biology : Fg & B. 45: 180-9. PMID 17656140 DOI: 10.1016/J.Fgb.2007.06.004  0.321
2007 Garscha U, Jernerén F, Chung D, Keller NP, Hamberg M, Oliw EH. Identification of dioxygenases required for Aspergillus development. Studies of products, stereochemistry, and the reaction mechanism. The Journal of Biological Chemistry. 282: 34707-18. PMID 17906293 DOI: 10.1074/Jbc.M705366200  0.361
2007 Rohlfs M, Albert M, Keller NP, Kempken F. Secondary chemicals protect mould from fungivory. Biology Letters. 3: 523-5. PMID 17686752 DOI: 10.1098/Rsbl.2007.0338  0.387
2007 Shwab EK, Bok JW, Tribus M, Galehr J, Graessle S, Keller NP. Histone deacetylase activity regulates chemical diversity in Aspergillus. Eukaryotic Cell. 6: 1656-64. PMID 17616629 DOI: 10.1128/Ec.00186-07  0.422
2007 Perrin RM, Fedorova ND, Bok JW, Cramer RA, Wortman JR, Kim HS, Nierman WC, Keller NP. Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. Plos Pathogens. 3: e50. PMID 17432932 DOI: 10.1371/Journal.Ppat.0030050  0.492
2007 Hoffmeister D, Keller NP. Natural products of filamentous fungi: enzymes, genes, and their regulation. Natural Product Reports. 24: 393-416. PMID 17390002 DOI: 10.1039/B603084J  0.406
2007 Bouhired S, Weber M, Kempf-Sontag A, Keller NP, Hoffmeister D. Accurate prediction of the Aspergillus nidulans terrequinone gene cluster boundaries using the transcriptional regulator LaeA. Fungal Genetics and Biology : Fg & B. 44: 1134-45. PMID 17291795 DOI: 10.1016/J.Fgb.2006.12.010  0.436
2007 Tsitsigiannis DI, Keller NP. Oxylipins as developmental and host-fungal communication signals. Trends in Microbiology. 15: 109-18. PMID 17276068 DOI: 10.1016/J.Tim.2007.01.005  0.72
2007 Hammond TM, Tsitsigiannis DI, Keller NP. Development of an Arabidopsis thaliana-based bioassay for investigating seed colonization by mycotoxigenic Aspergillus species Plant Pathology. 56: 848-854. DOI: 10.1111/J.1365-3059.2007.01644.X  0.719
2006 Keller N, Bok J, Chung D, Perrin RM, Keats Shwab E. LaeA, a global regulator of Aspergillus toxins. Medical Mycology. 44: S83-S85. PMID 30408938 DOI: 10.1080/13693780600835773  0.427
2006 Brodhagen M, Keller NP. Signalling pathways connecting mycotoxin production and sporulation. Molecular Plant Pathology. 7: 285-301. PMID 20507448 DOI: 10.1111/J.1364-3703.2006.00338.X  0.353
2006 Bok JW, Chung D, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Kirby KA, Keller NP. GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence. Infection and Immunity. 74: 6761-8. PMID 17030582 DOI: 10.1128/Iai.00780-06  0.469
2006 Bok JW, Noordermeer D, Kale SP, Keller NP. Secondary metabolic gene cluster silencing in Aspergillus nidulans. Molecular Microbiology. 61: 1636-45. PMID 16968230 DOI: 10.1111/J.1365-2958.2006.05330.X  0.399
2006 Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP. Genomic mining for Aspergillus natural products. Chemistry & Biology. 13: 31-7. PMID 16426969 DOI: 10.1016/J.Chembiol.2005.10.008  0.457
2006 Tsitsigiannis DI, Keller NP. Oxylipins act as determinants of natural product biosynthesis and seed colonization in Aspergillus nidulans. Molecular Microbiology. 59: 882-92. PMID 16420358 DOI: 10.1111/J.1365-2958.2005.05000.X  0.768
2006 Keller N, Bok J, Chung D, Perrin RM, Keats Shwab E. LaeA, a global regulator of Aspergillus toxins Medical Mycology. 44: 83-85. DOI: 10.1080/13693780600835773  0.313
2005 Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB, Bermejo C, Bennett J, Bowyer P, Chen D, Collins M, Coulsen R, ... ... Keller N, et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature. 438: 1151-6. PMID 16372009 DOI: 10.1038/Nature04332  0.391
2005 Keller NP, Turner G, Bennett JW. Fungal secondary metabolism - from biochemistry to genomics. Nature Reviews. Microbiology. 3: 937-47. PMID 16322742 DOI: 10.1038/Nrmicro1286  0.448
2005 Tsitsigiannis DI, Kunze S, Willis DK, Feussner I, Keller NP. Aspergillus infection inhibits the expression of peanut 13S-HPODE-forming seed lipoxygenases. Molecular Plant-Microbe Interactions : Mpmi. 18: 1081-9. PMID 16255247 DOI: 10.1094/Mpmi-18-1081  0.729
2005 Bok JW, Balajee SA, Marr KA, Andes D, Nielsen KF, Frisvad JC, Keller NP. LaeA, a regulator of morphogenetic fungal virulence factors. Eukaryotic Cell. 4: 1574-82. PMID 16151250 DOI: 10.1128/Ec.4.9.1574-1582.2005  0.43
2005 Maggio-Hall LA, Wilson RA, Keller NP. Fundamental contribution of beta-oxidation to polyketide mycotoxin production in planta. Molecular Plant-Microbe Interactions : Mpmi. 18: 783-93. PMID 16134890 DOI: 10.1094/Mpmi-18-0783  0.326
2005 Yu JH, Keller N. Regulation of secondary metabolism in filamentous fungi. Annual Review of Phytopathology. 43: 437-58. PMID 16078891 DOI: 10.1146/Annurev.Phyto.43.040204.140214  0.461
2005 Tsitsigiannis DI, Bok JW, Andes D, Nielsen KF, Frisvad JC, Keller NP. Aspergillus cyclooxygenase-like enzymes are associated with prostaglandin production and virulence. Infection and Immunity. 73: 4548-59. PMID 16040966 DOI: 10.1128/Iai.73.8.4548-4559.2005  0.751
2005 McDonald T, Brown D, Keller NP, Hammond TM. RNA silencing of mycotoxin production in Aspergillus and Fusarium species. Molecular Plant-Microbe Interactions : Mpmi. 18: 539-45. PMID 15986923 DOI: 10.1094/Mpmi-18-0539  0.378
2005 Tsitsigiannis DI, Kowieski TM, Zarnowski R, Keller NP. Three putative oxylipin biosynthetic genes integrate sexual and asexual development in Aspergillus nidulans. Microbiology (Reading, England). 151: 1809-21. PMID 15941990 DOI: 10.1099/Mic.0.27880-0  0.729
2005 Chang PK, Wilson RA, Keller NP, Cleveland TE. Deletion of the Delta12-oleic acid desaturase gene of a nonaflatoxigenic Aspergillus parasiticus field isolate affects conidiation and sclerotial development. Journal of Applied Microbiology. 97: 1178-84. PMID 15546408 DOI: 10.1111/J.1365-2672.2004.02424.X  0.342
2004 Wilkinson HH, Ramaswamy A, Sim SC, Keller NP. Increased conidiation associated with progression along the sterigmatocystin biosynthetic pathway. Mycologia. 96: 1190-8. PMID 21148941 DOI: 10.1080/15572536.2005.11832867  0.471
2004 Tsitsigiannis DI, Kowieski TM, Zarnowski R, Keller NP. Endogenous lipogenic regulators of spore balance in Aspergillus nidulans. Eukaryotic Cell. 3: 1398-411. PMID 15590815 DOI: 10.1128/Ec.3.6.1398-1411.2004  0.749
2004 Zhang YQ, Brock M, Keller NP. Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans. Genetics. 168: 785-94. PMID 15514053 DOI: 10.1534/Genetics.104.027540  0.556
2004 Wilson RA, Calvo AM, Chang PK, Keller NP. Characterization of the Aspergillus parasiticus delta12-desaturase gene: a role for lipid metabolism in the Aspergillus-seed interaction. Microbiology (Reading, England). 150: 2881-8. PMID 15347747 DOI: 10.1099/Mic.0.27207-0  0.435
2004 Calvo AM, Bok J, Brooks W, Keller NP. veA is required for toxin and sclerotial production in Aspergillus parasiticus. Applied and Environmental Microbiology. 70: 4733-9. PMID 15294809 DOI: 10.1128/Aem.70.8.4733-4739.2004  0.469
2004 Bok JW, Keller NP. LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryotic Cell. 3: 527-35. PMID 15075281 DOI: 10.1128/Ec.3.2.527-535.2004  0.474
2004 Zhang YQ, Keller NP. Blockage of methylcitrate cycle inhibits polyketide production in Aspergillus nidulans. Molecular Microbiology. 52: 541-50. PMID 15066039 DOI: 10.1111/J.1365-2958.2004.03994.X  0.598
2004 Wilson RA, Chang PK, Dobrzyn A, Ntambi JM, Zarnowski R, Keller NP. Two Delta9-stearic acid desaturases are required for Aspergillus nidulans growth and development. Fungal Genetics and Biology : Fg & B. 41: 501-9. PMID 15050539 DOI: 10.1016/J.Fgb.2003.12.009  0.351
2004 Tsitsigiannis DI, Zarnowski R, Keller NP. The lipid body protein, PpoA, coordinates sexual and asexual sporulation in Aspergillus nidulans. The Journal of Biological Chemistry. 279: 11344-53. PMID 14699095 DOI: 10.1074/Jbc.M310840200  0.695
2004 Maggio-Hall LA, Hammond TM, Keller NP. Chapter ten Aspergillus nidulans as a model system to study secondary metabolism Recent Advances in Phytochemistry. 38: 197-222. DOI: 10.1016/S0079-9920(04)80011-X  0.461
2003 Greene AV, Keller N, Haas H, Bell-Pedersen D. A circadian oscillator in Aspergillus spp. regulates daily development and gene expression. Eukaryotic Cell. 2: 231-7. PMID 12684372 DOI: 10.1128/Ec.2.2.231-237.2003  0.328
2002 Jin Y, Bok JW, Guzman-de-Peña D, Keller NP. Requirement of spermidine for developmental transitions in Aspergillus nidulans. Molecular Microbiology. 46: 801-12. PMID 12410837 DOI: 10.1046/J.1365-2958.2002.03201.X  0.353
2002 Calvo AM, Wilson RA, Bok JW, Keller NP. Relationship between secondary metabolism and fungal development. Microbiology and Molecular Biology Reviews : Mmbr. 66: 447-59, table of con. PMID 12208999 DOI: 10.1128/Mmbr.66.3.447-459.2002  0.418
2002 Fillinger S, Chaveroche MK, Shimizu K, Keller N, D'Enfert C. cAMP and ras signalling independently control spore germination in the filamentous fungus Aspergillus nidulans. Molecular Microbiology. 44: 1001-1016. PMID 12046590 DOI: 10.1046/J.1365-2958.2002.02933.X  0.331
2001 Wilson RA, Gardner HW, Keller NP. Cultivar-dependent expression of a maize lipoxygenase responsive to seed infesting fungi. Molecular Plant-Microbe Interactions : Mpmi. 14: 980-7. PMID 11497470 DOI: 10.1094/Mpmi.2001.14.8.980  0.419
2001 Calvo AM, Gardner HW, Keller NP. Genetic connection between fatty acid metabolism and sporulation in Aspergillus nidulans. The Journal of Biological Chemistry. 276: 25766-74. PMID 11352908 DOI: 10.1074/Jbc.M100732200  0.348
2001 Hicks J, Lockington RA, Strauss J, Dieringer D, Kubicek CP, Kelly J, Keller N. RcoA has pleiotropic effects on Aspergillus nidulans cellular development. Molecular Microbiology. 39: 1482-1493. PMID 11260466 DOI: 10.1046/J.1365-2958.2001.02332.X  0.404
2001 Tag A, Hicks J, Garifullina G, Ake C, Phillips TD, Beremand M, Keller N. G-protein signalling mediates differential production of toxic secondary metabolites. Molecular Microbiology. 38: 658-65. PMID 11069688 DOI: 10.1046/J.1365-2958.2000.02166.X  0.445
2000 Burow GB, Gardner HW, Keller NP. A peanut seed lipoxygenase responsive to Aspergillus colonization. Plant Molecular Biology. 42: 689-701. PMID 10809442 DOI: 10.1023/A:1006361305703  0.417
2000 Keller NP, Watanabe CM, Kelkar HS, Adams TH, Townsend CA. Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans. Applied and Environmental Microbiology. 66: 359-62. PMID 10618248 DOI: 10.1128/Aem.66.1.359-362.2000  0.407
1999 Calvo AM, Hinze LL, Gardner HW, Keller NP. Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. Applied and Environmental Microbiology. 65: 3668-73. PMID 10427064 DOI: 10.1128/Aem.65.8.3668-3673.1999  0.37
1998 Fernandes M, Keller NP, Adams TH. Sequence-specific binding by Aspergillus nidulans AflR, a C6 zinc cluster protein regulating mycotoxin biosynthesis. Molecular Microbiology. 28: 1355-65. PMID 9680223 DOI: 10.1046/J.1365-2958.1998.00907.X  0.395
1998 Gardner HW, Grove MJ, Keller NP. Soybean lipoxygenase is active on nonaqueous media at low moisture: a constraint to xerophilic fungi and aflatoxins? Journal of the American Oil Chemists' Society. 75: 1801-1808. DOI: 10.1007/S11746-998-0334-Y  0.341
1997 Hicks JK, Yu JH, Keller NP, Adams TH. Aspergillus sporulation and mycotoxin production both require inactivation of the FadA Gα protein-dependent signaling pathway Embo Journal. 16: 4916-4923. PMID 9305634 DOI: 10.1093/Emboj/16.16.4916  0.458
1997 Keller NP, Hohn TM. Metabolic pathway gene clusters in filamentous fungi Fungal Genetics and Biology. 21: 17-29. PMID 9126615 DOI: 10.1006/Fgbi.1997.0970  0.383
1997 Kelkar HS, Skloss TW, Haw JF, Keller NP, Adams TH. Aspergillus nidulans stcL encodes a putative cytochrome P-450 monooxygenase required for bisfuran desaturation during aflatoxin/sterigmatocystin biosynthesis. The Journal of Biological Chemistry. 272: 1589-94. PMID 8999832 DOI: 10.1074/Jbc.272.3.1589  0.423
1997 Brown DW, Adams TH, Keller NP. Aspergillus has distinct fatty acid synthases for primary and secondary metabolism. Proceedings of the National Academy of Sciences of the United States of America. 93: 14873-7. PMID 8962148 DOI: 10.1073/Pnas.93.25.14873  0.343
1997 Kelkar HS, Keller NP, Adams TH. Aspergillus nidulans stcP encodes an O-methyltransferase that is required for sterigmatocystin biosynthesis. Applied and Environmental Microbiology. 62: 4296-8. PMID 8900026 DOI: 10.1128/Aem.62.11.4296-4298.1996  0.306
1997 Burow GB, Nesbitt TC, Dunlap J, Keller NP. Seed lipoxygenase products modulate Aspergillus mycotoxin biosynthesis Molecular Plant-Microbe Interactions. 10: 380-387. DOI: 10.1094/Mpmi.1997.10.3.380  0.37
1996 Yu JH, Butchko RA, Fernandes M, Keller NP, Leonard TJ, Adams TH. Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. Current Genetics. 29: 549-55. PMID 8662194 DOI: 10.1007/Bf02426959  0.413
1996 Brown DW, Yu JH, Kelkar HS, Fernandes M, Nesbitt TC, Keller NP, Adams TH, Leonard TJ. Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans. Proceedings of the National Academy of Sciences of the United States of America. 93: 1418-22. PMID 8643646 DOI: 10.1073/Pnas.93.4.1418  0.434
1995 Keller NP, Segner S, Bhatnagar D, Adams TH. stcS, a putative P-450 monooxygenase, is required for the conversion of versicolorin A to sterigmatocystin in Aspergillus nidulans. Applied and Environmental Microbiology. 61: 3628-32. PMID 7486998 DOI: 10.1128/Aem.61.10.3628-3632.1995  0.402
1994 Keller NP, Kantz NJ, Adams TH. Aspergillus nidulans verA is required for production of the mycotoxin sterigmatocystin. Applied and Environmental Microbiology. 60: 1444-50. PMID 8017929 DOI: 10.1128/Aem.60.5.1444-1450.1994  0.418
1994 Keller NP. A Visual Pattern of Mycotoxin Production in Maize Kernels byAspergillusspp. Phytopathology. 84: 483. DOI: 10.1094/Phyto-84-483  0.347
1993 Yu J, Cary JW, Bhatnagar D, Cleveland TE, Keller NP, Chu FS. Cloning and characterization of a cDNA from Aspergillus parasiticus encoding an O-methyltransferase involved in aflatoxin biosynthesis Applied and Environmental Microbiology. 59: 3564-3571. PMID 8285664 DOI: 10.1128/Aem.59.11.3564-3571.1993  0.332
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