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Grant S. Schulert, Ph.D. - Publications

Affiliations: 
2009 University of Iowa, Iowa City, IA 
Area:
Microbiology Biology, Immunology, Cell Biology
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schulert GS, Kessel C. Molecular Pathways in the Pathogenesis of Systemic Juvenile Idiopathic Arthritis. Rheumatic Diseases Clinics of North America. 49: 895-911. PMID 37821202 DOI: 10.1016/j.rdc.2023.06.007  0.357
2023 Heshin-Bekenstein M, Baron S, Schulert G, Shusterman A, Fidel V, Ben-Shahar Y, Shukrun R, Binenbaum Y, Elhasid R. Neutrophils extracellular traps formation may serve as a biomarker for disease activity in oligoarticular juvenile idiopathic arthritis: a pilot study. Arthritis Research & Therapy. 25: 135. PMID 37525216 DOI: 10.1186/s13075-023-03104-9  0.308
2023 Macaraeg M, Schulert GS. Complications of complications: diagnosis and treatment of recurrent macrophage activation syndrome in a patient with well-controlled systemic juvenile idiopathic arthritis. Rmd Open. 9. PMID 36690384 DOI: 10.1136/rmdopen-2022-002611  0.314
2022 Schulert GS. The Big Bad Wolf: Macrophage Activation Syndrome in Childhood-Onset Systemic Lupus Erythematosus. The Journal of Rheumatology. 49: 1082-1084. PMID 36271722 DOI: 10.3899/jrheum.220780  0.341
2022 Chen G, Deutsch GH, Schulert G, Zheng H, Jang S, Trapnell B, Lee P, Macaubas C, Ho K, Schneider C, Saper VE, de Jesus AA, Krasnow M, Grom A, Goldbach-Mansky R, et al. Serum proteome analysis of systemic JIA and related lung disease identifies distinct inflammatory programs and biomarkers. Arthritis & Rheumatology (Hoboken, N.J.). PMID 35189047 DOI: 10.1002/art.42099  0.315
2021 Erkens R, Esteban Y, Towe C, Schulert G, Vastert S. Pathogenesis and Treatment of Refractory Disease Courses in Systemic Juvenile Idiopathic Arthritis: Refractory Arthritis, Recurrent Macrophage Activation Syndrome and Chronic Lung Disease. Rheumatic Diseases Clinics of North America. 47: 585-606. PMID 34635293 DOI: 10.1016/j.rdc.2021.06.003  0.351
2021 Gao DK, Salomonis N, Henderlight M, Woods C, Thakkar K, Grom AA, Thornton S, Jordan MB, Wikenheiser-Brokamp KA, Schulert GS. IFN-γ is essential for alveolar macrophage driven pulmonary inflammation in macrophage activation syndrome. Jci Insight. PMID 34314387 DOI: 10.1172/jci.insight.147593  0.314
2021 Rodriguez-Smith JJ, Verweyen EL, Clay GM, Esteban YM, de Loizaga SR, Baker EJ, Do T, Dhakal S, Lang SM, Grom AA, Grier D, Schulert GS. Inflammatory biomarkers in COVID-19-associated multisystem inflammatory syndrome in children, Kawasaki disease, and macrophage activation syndrome: a cohort study. The Lancet. Rheumatology. PMID 34124694 DOI: 10.1016/S2665-9913(21)00139-9  0.336
2021 Ombrello MJ, Schulert GS. COVID-19 and Cytokine Storm Syndrome: Are there lessons from Macrophage Activation Syndrome? Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 33684592 DOI: 10.1016/j.trsl.2021.03.002  0.302
2020 Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, Bassiri H, Behrens EM, Ferris A, Kernan KF, Schulert GS, Seo P, F Son MB, Tremoulet AH, Yeung RSM, Mudano AS, et al. American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and Hyperinflammation in COVID-19. Version 1. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32705809 DOI: 10.1002/Art.41454  0.343
2020 Canna SW, Schulert GS, de Jesus A, Pickering A, Brunner H, Gadina M, Levine S, Goldbach-Mansky R, Boutelle J, Sinha R, DeBenedetti F, Grom A. Proceedings from the 2 Next Gen Therapies for Systemic Juvenile Idiopathic Arthritis and Macrophage Activation Syndrome symposium held on October 3-4, 2019. Pediatric Rheumatology Online Journal. 18: 53. PMID 32664935 DOI: 10.1186/S12969-020-00444-7  0.454
2020 Henderson LA, Canna SW, Schulert GS, Volpi S, Lee PY, Kernan KF, Caricchio R, Mahmud S, Hazen MM, Halyabar O, Hoyt KJ, Han J, Grom AA, Gattorno M, Ravelli A, et al. On the alert for cytokine storm: Immunopathology in COVID-19. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32293098 DOI: 10.1002/Art.41285  0.353
2020 Schulert GS, Cron RQ. The genetics of macrophage activation syndrome. Genes and Immunity. PMID 32291394 DOI: 10.1038/S41435-020-0098-4  0.392
2020 Aljaberi N, Tronconi E, Schulert G, Grom AA, Lovell DJ, Huggins JL, Henrickson M, Brunner HI. The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis. Pediatric Rheumatology. 18: 1-6. PMID 31948488 DOI: 10.1186/S12969-020-0398-2  0.41
2020 Verweyen E, Holzinger D, Weinhage T, Hinze C, Wittkowski H, Pickkers P, Albeituni S, Verbist K, Nichols KE, Schulert G, Grom A, Foell D, Kessel C. Synergistic Signaling of TLR and IFNα/β Facilitates Escape of IL-18 Expression From Endotoxin Tolerance American Journal of Respiratory and Critical Care Medicine. 201: 526-539. PMID 31710506 DOI: 10.1164/Rccm.201903-0659Oc  0.343
2020 Angeles-Han ST, Utz VM, Thornton S, Schulert G, Rodriguez-Smith J, Kauffman A, Sproles A, Mwase N, Hennard T, Grom A, Altaye M, Holland GN. S100 Proteins, Cytokines, and Chemokines as Tear Biomarkers in Children with Juvenile Idiopathic Arthritis-associated Uveitis Ocular Immunology and Inflammation. 1-5. DOI: 10.1080/09273948.2020.1758731  0.338
2019 de Jesus AA, Hou Y, Brooks S, Malle L, Biancotto A, Huang Y, Calvo KR, Marrero B, Moir S, Oler AJ, Deng Z, Montealegre Sanchez GA, Ahmed A, Allenspach E, Arabshahi B, ... ... Schulert G, et al. Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. The Journal of Clinical Investigation. PMID 31874111 DOI: 10.1172/Jci129301  0.367
2019 Ferrara G, Giani T, Lieberman SM, Kremer C, Hong S, Indolfi G, Schulert G, Cron RQ, Mannion ML, Lapidus S, Armbrust W, Gonzales E, Jacquemin E, Koné-Paut I, Cimaz R. Alagille Syndrome and Chronic Arthritis: An International Case Series. The Journal of Pediatrics. PMID 31748120 DOI: 10.1016/J.Jpeds.2019.10.042  0.378
2019 Lee PY, Schulert GS, Canna SW, Huang Y, Sundel J, Li Y, Hoyt KJ, Blaustein RB, Wactor A, Do T, Halyabar O, Chang MH, Dedeoglu F, Case SM, Meidan E, et al. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Annals of the Rheumatic Diseases. PMID 31707357 DOI: 10.1136/Annrheumdis-2019-216030  0.448
2019 Abid Q, Best Rocha A, Larsen CP, Schulert G, Marsh R, Yasin S, Patty-Resk C, Valentini RP, Adams M, Baracco R. APOL1-Associated Collapsing Focal Segmental Glomerulosclerosis in a Patient With Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset in Infancy (SAVI). American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 31601430 DOI: 10.1053/J.Ajkd.2019.07.010  0.345
2019 Niu X, Schulert GS. Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis. Frontiers in Immunology. 10: 2217. PMID 31572403 DOI: 10.3389/Fimmu.2019.02217  0.332
2019 Saper VE, Chen G, Deutsch GH, Guillerman RP, Birgmeier J, Jagadeesh K, Canna S, Schulert G, Deterding R, Xu J, Leung AN, Bouzoubaa L, Abulaban K, Baszis K, Behrens EM, et al. Emergent high fatality lung disease in systemic juvenile arthritis. Annals of the Rheumatic Diseases. PMID 31562126 DOI: 10.1136/Annrheumdis-2019-216040  0.341
2019 Schulert GS, Yasin S, Carey B, Chalk C, Do T, Schapiro AH, Husami A, Watts A, Brunner HI, Huggins J, Mellins ED, Morgan EM, Ting T, Trapnell BC, Wikenheiser-Brokamp KA, et al. Systemic Juvenile Idiopathic Arthritis-Lung Disease: Characterization and Risk Factors. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31379071 DOI: 10.1002/Art.41073  0.353
2019 Yasin S, Solomon K, Canna SW, Girard-Guyonvarc'h C, Gabay C, Schiffrin E, Sleight A, Grom AA, Schulert GS. IL-18 as therapeutic target in a patient with resistant systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome. Rheumatology (Oxford, England). PMID 31359055 DOI: 10.1093/Rheumatology/Kez284  0.424
2019 Yasin S, Fall N, Brown RA, Henderlight M, Canna SW, Girard-Guyonvarc'h C, Gabay C, Grom AA, Schulert GS. IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome. Rheumatology (Oxford, England). PMID 31326996 DOI: 10.1093/Rheumatology/Kez282  0.465
2019 Thornton S, Tan R, Sproles A, Do T, Schick J, Grom AA, DeLay M, Schulert GS. A Multiparameter Flow Cytometry Analysis Panel to Assess CD163 mRNA and Protein in Monocyte and Macrophage Populations in Hyperinflammatory Diseases. Journal of Immunology (Baltimore, Md. : 1950). PMID 30683706 DOI: 10.4049/Jimmunol.1800765  0.306
2019 Takkellapati D, Niu X, Do T, Schulert G. Thu0508 Changes In Mir-17–92 Cluster Expression Link Systemic Juvenile Idiopathic Arthritis, Monocyte-To-Macrophage Differentiation, And Interferon Regulation Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2019-Eular.6092  0.312
2019 Schulert G, Do T, Dhakal S, Fall N, Medvedovich M, Salomonis N, Grom A. Op0150 Monocyte And Macrophage Transcriptional Phenotypes In Systemic Juvenile Idiopathic Arthritis Reveal Trim8 As A Mediator Of Ifngamma Hyperresponsiveness And Risk For Macrophage Activation Syndrome Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2019-Eular.5745  0.431
2019 Tronconi E, Aljaberi N, Merritt A, Grom A, Schulert G, Huggins J, Henrickson M, Brunner H. Ab1065 The Utilisation Of S100 Proteins Testing In Pediatric Rheumatology Patients In A Tertiary Care Institution And Implications For Care Annals of the Rheumatic Diseases. 78: 1995-1996. DOI: 10.1136/Annrheumdis-2019-Eular.3645  0.379
2019 Chen G, Saper V, Deutsch G, Guillerman R, Jagadeesh K, Schulert G, Canna S, Lu Y, Birgmeier J, Leung A, Grom A, Bejerano G, Davis M, Khatri P, Mellins E. P127 Lung disease in systemic JIA: an emerging problem linked with young age and anti-IL-1/IL-6 Annals of the Rheumatic Diseases. 78. DOI: 10.1136/Annrheumdis-2018-Ewrr2019.115  0.378
2018 Brown RA, Henderlight M, Do T, Yasin S, Grom AA, DeLay M, Thornton S, Schulert GS. Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease. Frontiers in Immunology. 9: 2995. PMID 30619348 DOI: 10.3389/Fimmu.2018.02995  0.449
2018 Ter Haar NM, van Delft ALJ, Annink KV, van Stel H, Al-Mayouf SM, Amaryan G, Anton J, Barron KS, Benseler S, Brogan PA, Cantarini L, Cattalini M, Cochino AV, de Benedetti F, Dedeoglu F, ... ... Schulert G, et al. In silico validation of the Autoinflammatory Disease Damage Index. Annals of the Rheumatic Diseases. PMID 30077992 DOI: 10.1136/Annrheumdis-2018-213725  0.36
2018 Yasin S, Schulert GS. Systemic juvenile idiopathic arthritis and macrophage activation syndrome: update on pathogenesis and treatment. Current Opinion in Rheumatology. PMID 29870499 DOI: 10.1097/Bor.0000000000000526  0.455
2018 DeSena AD, Do T, Schulert GS. Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade. Journal of Neuroinflammation. 15: 38. PMID 29426321 DOI: 10.1186/S12974-018-1063-2  0.302
2018 Schulert GS, Canna SW. Convergent pathways of the hyperferritinemic syndromes. International Immunology. PMID 29420734 DOI: 10.1093/Intimm/Dxy012  0.488
2018 Schulert GS, Zhang M, Husami A, Fall N, Brunner H, Zhang K, Cron RQ, Grom AA. Novel UNC13D intronic variant disrupting a NFκB enhancer in a patient with recurrent macrophage activation syndrome and systemic juvenile idiopathic arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29409136 DOI: 10.1002/Art.40438  0.44
2018 Do T, Tan R, Bennett M, Medvedovic M, Grom AA, Shen N, Thornton S, Schulert GS. MicroRNA networks associated with active systemic juvenile idiopathic arthritis regulate CD163 expression and anti-inflammatory functions in macrophages through two distinct mechanisms. Journal of Leukocyte Biology. 103: 71-85. PMID 29345059 DOI: 10.1002/Jlb.2A0317-107R  0.371
2017 Schulert GS, Minoia F, Bohnsack J, Cron RQ, Hashad S, Kone-Paut I, Kostik M, Lovell D, Maritsi D, Nigrovic PA, Pal P, Ravelli A, Shimizu M, Stanevicha V, Vastert S, et al. Biologic therapy modifies clinical and laboratory features of macrophage activation syndrome associated with systemic juvenile idiopathic arthritis. Arthritis Care & Research. PMID 28499329 DOI: 10.1002/Acr.23277  0.45
2016 Favier LA, Schulert GS. Mevalonate kinase deficiency: current perspectives. The Application of Clinical Genetics. 9: 101-10. PMID 27499643 DOI: 10.2147/Tacg.S93933  0.354
2016 Bracaglia C, de Graaf K, Pires Marafon D, Guilhot F, Ferlin W, Prencipe G, Caiello I, Davì S, Schulert G, Ravelli A, Grom AA, de Min C, De Benedetti F. Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. Annals of the Rheumatic Diseases. PMID 27296321 DOI: 10.1136/Annrheumdis-2015-209020  0.44
2016 Schulert GS, Fall N, Harley JB, Shen N, Lovell DJ, Thornton S, Grom AA. Monocyte microRNA expression in active systemic juvenile idiopathic arthritis implicates miR-125a-5p in polarized monocyte phenotypes. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27014994 DOI: 10.1002/Art.39694  0.368
2016 Thornton S, Do TD, Tan R, Sproles A, Bennett M, Medvedovic M, DeLay M, Shen N, Grom A, Schulert G. OP0012 Microrna Associated with Active Systemic Juvenile Idiopathic Arthritis Regulate CD163 Expression in Polarized Macrophages through Two Distinct Mechanisms Annals of the Rheumatic Diseases. 75: 57-57. DOI: 10.1136/Annrheumdis-2016-Eular.4286  0.349
2015 Schulert GS, Grom AA. Pathogenesis of macrophage activation syndrome and potential for cytokine- directed therapies. Annual Review of Medicine. 66: 145-59. PMID 25386930 DOI: 10.1146/annurev-med-061813-012806  0.361
2015 Bracaglia C, Marafon DP, Caiello I, de Graaf K, Guilhot F, Ferlin W, Davì S, Schulert G, Ravelli A, Grom A, Nelson R, de Min C, De Benedetti F. High levels of interferon-gamma (IFNγ) in macrophage activation syndrome (MAS) and CXCL9 levels as a biomarker for IFNγ production in MAS Pediatric Rheumatology. DOI: 10.1186/1546-0096-13-S1-O84  0.422
2015 Schulert G, Fall N, Shen N, Thornton S, Grom A. OP0283 Microrna 125A-5P has Increased Expression in Active Systemic Juvenile Idiopathic Arthritis and is an Essential Modulator of Regulatory Macrophage Phenotypes in Vitro Annals of the Rheumatic Diseases. 74: 179-180. DOI: 10.1136/Annrheumdis-2015-Eular.4865  0.408
2014 Schulert GS, Bove K, McMasters R, Campbell K, Leslie N, Grom AA. Mevalonate kinase deficiency associated with recurrent liver dysfunction, macrophage activation syndrome and perforin gene polymorphism. Arthritis Care & Research. PMID 25469482 DOI: 10.1002/Acr.22527  0.33
2014 Schulert GS, Grom AA. Macrophage activation syndrome and cytokine-directed therapies. Best Practice & Research. Clinical Rheumatology. 28: 277-92. PMID 24974063 DOI: 10.1016/j.berh.2014.03.002  0.322
2014 Schulert G, Fall N, Shen N, Grom A. Differential monocyte microrna expression profiles in children with active systemic juvenile idiopathic arthritis Pediatric Rheumatology. 12: 59. DOI: 10.1186/1546-0096-12-S1-P59  0.414
2014 Bracaglia C, Caiello I, Graaf KD, D'Ario G, Guilhot F, Ferlin W, Melli L, Prencipe G, Davì S, Schulert G, Ravelli A, Grom A, Min CD, Benedetti FD. Interferon-gamma (IFNy) in macrophage activation syndrome (MAS) associated with systemic juvenile idiopathic arthritis (sJIA). High levels in patients and a role in a murine mas model Pediatric Rheumatology. 12: 1-2. DOI: 10.1186/1546-0096-12-S1-O3  0.44
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