Year |
Citation |
Score |
2019 |
Cui P, Liu X, Zhao K, Hou S, Chen C, Zhao D, Zeng H. The novel axis of YAP1, transcription enhancer factor 3 and Down Syndrome Candidate Region 1 isoform 1L is a common signaling pathway downstream of several angiogenic factors. Microvascular Research. 103955. PMID 31733305 DOI: 10.1016/J.Mvr.2019.103955 |
0.378 |
|
2019 |
Chen C, Li Y, Hou S, Bourbon PM, Qin L, Zhao K, Ye T, Zhao D, Zeng H. Orphan nuclear receptor TR3/Nur77 biologics inhibit tumor growth by targeting angiogenesis and tumor cells. Microvascular Research. 103934. PMID 31654655 DOI: 10.1016/J.Mvr.2019.103934 |
0.361 |
|
2019 |
Peng J, Zhao S, Li Y, Niu G, Chen C, Ye T, Zhao D, Zeng H. DLL4 and Jagged1 are angiogenic targets of orphan nuclear receptor TR3/Nur77. Microvascular Research. PMID 30930165 DOI: 10.1016/J.Mvr.2019.03.006 |
0.415 |
|
2018 |
Ye T, Peng J, Liu X, Hou S, Niu G, Li Y, Zeng H, Zhao D. Orphan nuclear receptor TR3/Nur77 differentially regulates the expression of integrins in angiogenesis. Microvascular Research. PMID 30391133 DOI: 10.1016/J.Mvr.2018.10.011 |
0.338 |
|
2017 |
Zeng Y, Ye X, Liao D, Huang S, Mao H, Zhao D, Zeng H. Expressions of Orphan Nuclear Receptor TR3/Nur77 in Chronic Hepatopathy and Its Clinical Significance. Journal of Clinical & Experimental Oncology. 6. PMID 28856167 DOI: 10.4172/2324-9110.1000188 |
0.302 |
|
2016 |
Jia J, Ye T, Cui P, Hua Q, Zeng H, Zhao D. AP-1 transcription factor mediates VEGF-induced endothelial cell migration and proliferation. Microvascular Research. PMID 26860974 DOI: 10.1016/J.Mvr.2016.02.004 |
0.402 |
|
2015 |
Zhou L, Cui P, Zhao S, Ye T, Li Y, Peng J, Niu G, Zhao D, Zeng H. Differential function and regulation of orphan nuclear receptor TR3 isoforms in endothelial cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26440050 DOI: 10.1007/S13277-015-4157-9 |
0.422 |
|
2015 |
Li Y, Bourbon PM, Grant MA, Peng J, Ye T, Zhao D, Zeng H. Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis. Oncotarget. 6: 24261-76. PMID 26155943 DOI: 10.18632/Oncotarget.4637 |
0.305 |
|
2015 |
Niu G, Ye T, Qin L, Bourbon PM, Chang C, Zhao S, Li Y, Zhou L, Cui P, Rabinovitz I, Mercurio AM, Zhao D, Zeng H. Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 131-40. PMID 25326539 DOI: 10.1096/Fj.14-257550 |
0.362 |
|
2014 |
Zhao S, Zhou L, Niu G, Li Y, Zhao D, Zeng H. Differential regulation of orphan nuclear receptor TR3 transcript variants by novel vascular growth factor signaling pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4524-33. PMID 25016027 DOI: 10.1096/Fj.13-248401 |
0.414 |
|
2013 |
Qin L, Zhao D, Xu J, Ren X, Terwilliger EF, Parangi S, Lawler J, Dvorak HF, Zeng H. The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1. Blood. 121: 2154-64. PMID 23315169 DOI: 10.1182/Blood-2012-07-443903 |
0.365 |
|
2011 |
Koon HW, Shih DQ, Hing TC, Chen J, Ho S, Zhao D, Targan SR, Pothoulakis C. Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells. The American Journal of Pathology. 179: 2315-26. PMID 21945803 DOI: 10.1016/J.Ajpath.2011.07.038 |
0.404 |
|
2011 |
Koon HW, Shih DQ, Chen J, Bakirtzi K, Hing TC, Law I, Ho S, Ichikawa R, Zhao D, Xu H, Gallo R, Dempsey P, Cheng G, Targan SR, Pothoulakis C. Cathelicidin signaling via the Toll-like receptor protects against colitis in mice. Gastroenterology. 141: 1852-63.e1-3. PMID 21762664 DOI: 10.1053/J.Gastro.2011.06.079 |
0.355 |
|
2011 |
Zhao D, Qin L, Bourbon PM, James L, Dvorak HF, Zeng H. Orphan nuclear transcription factor TR3/Nur77 regulates microvessel permeability by targeting endothelial nitric oxide synthase and destabilizing endothelial junctions. Proceedings of the National Academy of Sciences of the United States of America. 108: 12066-71. PMID 21730126 DOI: 10.1073/Pnas.1018438108 |
0.393 |
|
2011 |
Zhao D, Bakirtzi K, Zhan Y, Zeng H, Koon HW, Pothoulakis C. Insulin-like growth factor-1 receptor transactivation modulates the inflammatory and proliferative responses of neurotensin in human colonic epithelial cells. The Journal of Biological Chemistry. 286: 6092-9. PMID 21212273 DOI: 10.1074/Jbc.M110.192534 |
0.445 |
|
2011 |
Liu X, Zhao D, James L, Li J, Zeng H. Requirement of the nuclear localization of transcription enhancer factor 3 for proliferation, migration, tube formation, and angiogenesis induced by vascular endothelial growth factor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1188-97. PMID 21169383 DOI: 10.1096/Fj.10-167619 |
0.346 |
|
2011 |
Zhao D, Desai S, Zeng H. VEGF stimulates PKD-mediated CREB-dependent orphan nuclear receptor Nurr1 expression: role in VEGF-induced angiogenesis. International Journal of Cancer. 128: 2602-12. PMID 20715116 DOI: 10.1002/Ijc.25600 |
0.418 |
|
2011 |
Koon H, Hing T, Zhao D, Moyer M, Pothoulakis C. Substance P induces angiogenic factor CCN1 expression via histone deacetylase activity in human colonic epithelial cells.P-010. Inflammatory Bowel Diseases. 17. DOI: 10.1093/Ibd/17.Supplement1.S15 |
0.346 |
|
2011 |
Koon HW, Hing TC, Zhao D, Moyer MP, Pothoulakis C. Substance P Induces Angiogenic Factor CCN1 Expression via Histone Deacetylase Activity in Human Colonic Epithelial Cells Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63469-0 |
0.368 |
|
2011 |
Koon HW, Shih DQ, Hing TC, Zhao D, Xu H, Moyer MP, Gallo R, Pothoulakis C. Roles of Endogenous and Exogenous Cathelicidin During Colonic Inflammation Gastroenterology. 140: S-486. DOI: 10.1016/S0016-5085(11)62004-0 |
0.313 |
|
2010 |
Koon HW, Shih D, Karagiannides I, Zhao D, Fazelbhoy Z, Hing T, Xu H, Lu B, Gerard N, Pothoulakis C. Substance P modulates colitis-associated fibrosis. The American Journal of Pathology. 177: 2300-9. PMID 20889569 DOI: 10.2353/Ajpath.2010.100314 |
0.384 |
|
2009 |
Chen X, Fruehauf J, Goldsmith JD, Xu H, Katchar KK, Koon HW, Zhao D, Kokkotou EG, Pothoulakis C, Kelly CP. Saccharomyces boulardii inhibits EGF receptor signaling and intestinal tumor growth in Apc(min) mice. Gastroenterology. 137: 914-23. PMID 19482027 DOI: 10.1053/J.Gastro.2009.05.050 |
0.426 |
|
2009 |
Koon HW, Kim YS, Xu H, Kumar A, Zhao D, Karagiannides I, Dobner PR, Pothoulakis C. Neurotensin induces IL-6 secretion in mouse preadipocytes and adipose tissues during 2,4,6,-trinitrobenzensulphonic acid-induced colitis. Proceedings of the National Academy of Sciences of the United States of America. 106: 8766-71. PMID 19443690 DOI: 10.1073/Pnas.0903499106 |
0.403 |
|
2009 |
Koon HW, Zhao D, Kumar A, Xu H, Moyer MP, Pothoulakis C. 985 Substance P Mediates Colonic Fibrosis in Chronic Trinitrobenzene Sulfonic Acid (TNBS)-Treated Mice and Collagen Synthesis in Human Colonic Fibroblasts Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60683-1 |
0.333 |
|
2008 |
Liu X, Zhao D, Qin L, Li J, Zeng H. Transcription enhancer factor 3 (TEF3) mediates the expression of Down syndrome candidate region 1 isoform 1 (DSCR1-1L) in endothelial cells. The Journal of Biological Chemistry. 283: 34159-67. PMID 18840614 DOI: 10.1074/Jbc.M806338200 |
0.362 |
|
2008 |
Koon HW, Zhao D, Xu H, Bowe C, Moss A, Moyer MP, Pothoulakis C. Substance P-mediated expression of the pro-angiogenic factor CCN1 modulates the course of colitis. The American Journal of Pathology. 173: 400-10. PMID 18599605 DOI: 10.2353/Ajpath.2008.080222 |
0.419 |
|
2008 |
Koon HW, Zhao D, Xu H, Pothoulakis C. 916 Substance P Mediates Development of Colon Tumors in DSS-Exposed APC/Min Mice and Cultured Human Colon Cancer Cells Gastroenterology. 134: A-132-A-133. DOI: 10.1016/S0016-5085(08)60616-2 |
0.323 |
|
2007 |
Zhao D. Protein kinase Cdelta-mediated CREB activation regulates ghrelin-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colonic epithelial cells. Journal of Cellular Biochemistry. 102: 1245-55. PMID 17455223 DOI: 10.1002/Jcb.21355 |
0.423 |
|
2007 |
Koon HW, Zhao D, Zhan Y, Moyer MP, Pothoulakis C. Substance P mediates antiapoptotic responses in human colonocytes by Akt activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 2013-8. PMID 17264209 DOI: 10.1073/Pnas.0610664104 |
0.388 |
|
2007 |
Zhao D, Zhan Y, Zeng H, Koon HW, Moyer MP, Pothoulakis C. Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells. International Journal of Cancer. 120: 1652-6. PMID 17230532 DOI: 10.1002/Ijc.22407 |
0.391 |
|
2006 |
Qin L, Zhao D, Liu X, Nagy JA, Hoang MV, Brown LF, Dvorak HF, Zeng H. Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway. Molecular Cancer Research : McR. 4: 811-20. PMID 17114339 DOI: 10.1158/1541-7786.Mcr-06-0126 |
0.374 |
|
2006 |
Qin L, Zeng H, Zhao D. Requirement of protein kinase D tyrosine phosphorylation for VEGF-A165-induced angiogenesis through its interaction and regulation of phospholipase Cgamma phosphorylation. The Journal of Biological Chemistry. 281: 32550-8. PMID 16891660 DOI: 10.1074/Jbc.M604853200 |
0.36 |
|
2006 |
Zhao D, Pothoulakis C. Effects of NT on gastrointestinal motility and secretion, and role in intestinal inflammation. Peptides. 27: 2434-44. PMID 16872719 DOI: 10.1016/J.Peptides.2005.12.016 |
0.309 |
|
2006 |
Koon HW, Zhao D, Zhan Y, Rhee SH, Moyer MP, Pothoulakis C. Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 5050-9. PMID 16585602 DOI: 10.4049/Jimmunol.176.8.5050 |
0.42 |
|
2006 |
Zhao D, Zhan Y, Zeng H, Moyer MP, Mantzoros CS, Pothoulakis C. Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells. Journal of Cellular Biochemistry. 97: 1317-27. PMID 16552751 DOI: 10.1002/Jcb.20744 |
0.44 |
|
2006 |
Zeng H, Qin L, Zhao D, Tan X, Manseau EJ, Van Hoang M, Senger DR, Brown LF, Nagy JA, Dvorak HF. Orphan nuclear receptor TR3/Nur77 regulates VEGF-A-induced angiogenesis through its transcriptional activity. The Journal of Experimental Medicine. 203: 719-29. PMID 16520388 DOI: 10.1084/Jem.20051523 |
0.403 |
|
2005 |
Koon HW, Zhao D, Zhan Y, Simeonidis S, Moyer MP, Pothoulakis C. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation. The Journal of Pharmacology and Experimental Therapeutics. 314: 1393-400. PMID 15917399 DOI: 10.1124/Jpet.105.088013 |
0.408 |
|
2005 |
Na X, Zhao D, Koon HW, Kim H, Husmark J, Moyer MP, Pothoulakis C, LaMont JT. Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes. Gastroenterology. 128: 1002-11. PMID 15825081 DOI: 10.1053/J.Gastro.2005.01.053 |
0.395 |
|
2005 |
Zhao D, Zhan Y, Zeng H, Koon HW, Moyer MP, Pothoulakis C. Neurotensin stimulates interleukin-8 expression through modulation of I kappa B alpha phosphorylation and p65 transcriptional activity: involvement of protein kinase C alpha. Molecular Pharmacology. 67: 2025-31. PMID 15755906 DOI: 10.1124/Mol.104.010801 |
0.415 |
|
2004 |
Koon HW, Zhao D, Na X, Moyer MP, Pothoulakis C. Metalloproteinases and transforming growth factor-alpha mediate substance P-induced mitogen-activated protein kinase activation and proliferation in human colonocytes. The Journal of Biological Chemistry. 279: 45519-27. PMID 15319441 DOI: 10.1074/Jbc.M408523200 |
0.399 |
|
2004 |
Zhao D, Zhan Y, Koon HW, Zeng H, Keates S, Moyer MP, Pothoulakis C. Metalloproteinase-dependent transforming growth factor-alpha release mediates neurotensin-stimulated MAP kinase activation in human colonic epithelial cells. The Journal of Biological Chemistry. 279: 43547-54. PMID 15247267 DOI: 10.1074/Jbc.M401453200 |
0.403 |
|
2003 |
Zhao D, Pothoulakis C. Rho GTPases as therapeutic targets for the treatment of inflammatory diseases. Expert Opinion On Therapeutic Targets. 7: 583-92. PMID 14498821 DOI: 10.1517/14728222.7.5.583 |
0.361 |
|
2003 |
Zeng H, Zhao D, Yang S, Datta K, Mukhopadhyay D. Heterotrimeric G alpha q/G alpha 11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling. The Journal of Biological Chemistry. 278: 20738-45. PMID 12670961 DOI: 10.1074/Jbc.M209712200 |
0.407 |
|
2003 |
Mykoniatis A, Anton PM, Wlk M, Wang CC, Ungsunan L, Blüher S, Venihaki M, Simeonidis S, Zacks J, Zhao D, Sougioultzis S, Karalis K, Mantzoros C, Pothoulakis C. Leptin mediates Clostridium difficile toxin A-induced enteritis in mice. Gastroenterology. 124: 683-91. PMID 12612907 DOI: 10.1053/Gast.2003.50101 |
0.359 |
|
2003 |
Simeonidis S, Castagliuolo I, Pan A, Liu J, Wang CC, Mykoniatis A, Pasha A, Valenick L, Sougioultzis S, Zhao D, Pothoulakis C. Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter. Proceedings of the National Academy of Sciences of the United States of America. 100: 2957-62. PMID 12594338 DOI: 10.1073/Pnas.0530112100 |
0.34 |
|
2003 |
Zhao D, Kuhnt-Moore S, Zeng H, Wu JS, Moyer MP, Pothoulakis C. Neurotensin stimulates IL-8 expression in human colonic epithelial cells through Rho GTPase-mediated NF-kappa B pathways. American Journal of Physiology. Cell Physiology. 284: C1397-404. PMID 12584113 DOI: 10.1152/Ajpcell.00328.2002 |
0.387 |
|
2003 |
Simeonidis S, Pan A, Mykoniatis A, Zhao D, Moyer M, Pothoulakis C. The role of the I kappa B kinases in the substance P-induced inflammation of the GI tract Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82357-0 |
0.318 |
|
2003 |
Zhao D, Kuhnt-Moore S, Zeng H, Wu JS, Moyer MP, Pothoulakis C. Neurotensin stimulates interleukin-8 expression in human colonic epithelial cells through Rho GTPase-mediated NFkappaB pathways Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82354-5 |
0.387 |
|
2002 |
Zeng H, Zhao D, Mukhopadhyay D. KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA. The Journal of Biological Chemistry. 277: 46791-8. PMID 12244099 DOI: 10.1074/Jbc.M206133200 |
0.413 |
|
2002 |
Zhao D, Kuhnt-Moore S, Zeng H, Pan A, Wu JS, Simeonidis S, Moyer MP, Pothoulakis C. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. The Biochemical Journal. 368: 665-72. PMID 12169092 DOI: 10.1042/Bj20020950 |
0.387 |
|
2002 |
Zeng H, Zhao D, Mukhopadhyay D. Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1. The Journal of Biological Chemistry. 277: 4003-9. PMID 11726672 DOI: 10.1074/Jbc.M110842200 |
0.406 |
|
2001 |
Layne MD, Patel A, Chen YH, Rebel VI, Carvajal IM, Pellacani A, Ith B, Zhao D, Schreiber BM, Yet SF, Lee ME, Storch J, Perrella MA. Role of macrophage-expressed adipocyte fatty acid binding protein in the development of accelerated atherosclerosis in hypercholesterolemic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2733-5. PMID 11606480 DOI: 10.1096/Fj.01-0374Fje |
0.619 |
|
2001 |
Zhao D, Keates AC, Kuhnt-Moore S, Moyer MP, Kelly CP, Pothoulakis C. Signal Transduction Pathways Mediating Neurotensin-stimulated Interleukin-8 Expression in Human Colonocytes Journal of Biological Chemistry. 276: 44464-44471. PMID 11574537 DOI: 10.1074/Jbc.M104942200 |
0.375 |
|
2001 |
Perrella MA, Pellacani A, Layne MD, Patel A, Zhao D, Schreiber BM, Storch J, Feinberg MW, Hsieh CM, Haber E, Lee ME. Absence of adipocyte fatty acid binding protein prevents the development of accelerated atherosclerosis in hypercholesterolemic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1774-6. PMID 11481226 DOI: 10.1096/Fj.01-0017Fje |
0.616 |
|
2001 |
Zhao D, Letterman J, Schreiber BM. beta-Migrating very low density lipoprotein (beta VLDL) activates smooth muscle cell mitogen-activated protein (MAP) kinase via G protein-coupled receptor-mediated transactivation of the epidermal growth factor (EGF) receptor: effect of MAP kinase activation on beta VLDL plus EGF-induced cell proliferation. The Journal of Biological Chemistry. 276: 30579-88. PMID 11375998 DOI: 10.1074/Jbc.M103761200 |
0.623 |
|
2001 |
Zhao D, Keates A, Kuhnt-Moore S, Moyer MP, Pothoulakis C. Neurotensin (NT) stimulates IL-8 synthesis in non-malignant human colonocytes via NF-κB and MAP kinase-dependent pathways Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81533-8 |
0.321 |
|
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