| Year |
Citation |
Score |
| 2002 |
Carastro LM, Tan CK, Selg M, Jack HM, So AG, Downey KM. Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta. Nucleic Acids Research. 30: 2232-43. PMID 12000843 DOI: 10.1093/Nar/30.10.2232 |
0.578 |
|
| 2002 |
Lu X, Tan CK, Zhou JQ, You M, Carastro LM, Downey KM, So AG. Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta. The Journal of Biological Chemistry. 277: 24340-5. PMID 11986310 DOI: 10.1074/Jbc.M200065200 |
0.565 |
|
| 2001 |
He H, Tan CK, Downey KM, So AG. A tumor necrosis factor α- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase δ and proliferating cell nuclear antigen Proceedings of the National Academy of Sciences of the United States of America. 98: 11979-11984. PMID 11593007 DOI: 10.1073/Pnas.221452098 |
0.417 |
|
| 1999 |
Kramata P, Downey KM. 9-(2-phosphonylmethoxyethyl) derivatives of purine nucleotide analogs: A comparison of their metabolism and interaction with cellular DNA synthesis Molecular Pharmacology. 56: 1262-1270. PMID 10570054 DOI: 10.1124/Mol.56.6.1262 |
0.598 |
|
| 1999 |
Mozzherin DJ, Tan CK, Downey KM, Fisher PA. Architecture of the active DNA polymerase δ·proliferating cell nuclear antigen·template-primer complex Journal of Biological Chemistry. 274: 19862-19867. PMID 10391931 DOI: 10.1074/Jbc.274.28.19862 |
0.562 |
|
| 1999 |
Zaika A, Mozzherin DJ, Tan CK, Downey KM, Fisher PA. A two-dimensional support for selective binding of polyhistidine-tagged proteins: Identification of a proliferating cell nuclear antigen point mutant with altered function in vitro Analytical Biochemistry. 268: 193-200. PMID 10075808 DOI: 10.1006/Abio.1998.3074 |
0.484 |
|
| 1998 |
Terashima I, Suzuki N, Dasaradhi L, Tan CK, Downey KM, Shibutani S. Translesional synthesis on DNA templates containing an estrogen quinone- derived adduct: N2-(2-hydroxyestron-6-yl)-2'-deoxyguanosine and N6-(2- hydroxyestron-6-yl)-2'-deoxyadenosine Biochemistry. 37: 13807-13815. PMID 9753470 DOI: 10.1021/Bi981235E |
0.382 |
|
| 1998 |
Kramata P, Downey KM, Paborsky LR. Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase δ and ε in vitro Journal of Biological Chemistry. 273: 21966-21971. PMID 9705337 DOI: 10.1074/Jbc.273.34.21966 |
0.606 |
|
| 1997 |
Mozzherin DJ, Shibutani S, Tan CK, Downey KM, Fisher PA. Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase δ Proceedings of the National Academy of Sciences of the United States of America. 94: 6126-6131. PMID 9177181 DOI: 10.1073/Pnas.94.12.6126 |
0.536 |
|
| 1997 |
Zhou JQ, He H, Tan CK, Downey KM, So AG. The small subunit is required for functional interaction of DNA polymerase δ with the proliferating cell nuclear antigen Nucleic Acids Research. 25: 1094-1099. PMID 9092615 DOI: 10.1093/Nar/25.6.1094 |
0.601 |
|
| 1996 |
Mozzherin DJ, McConnell M, Jasko MV, Krayevsky AA, Tan CK, Downey KM, Fisher PA. Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase δ Journal of Biological Chemistry. 271: 31711-31717. PMID 8940194 DOI: 10.1074/jbc.271.49.31711 |
0.488 |
|
| 1996 |
Zhou JQ, Tan CK, So AG, Downey KM. Purification and characterization of the catalytic subunit of human DNA polymerase δ expressed in baculovirus-infected insect cells Journal of Biological Chemistry. 271: 29740-29745. PMID 8939909 DOI: 10.1074/Jbc.271.47.29740 |
0.608 |
|
| 1996 |
McConnell M, Miller H, Mozzherin DJ, Quamina A, Tan CK, Downey KM, Fisher PA. The mammalian DNA polymerase delta--proliferating cell nuclear antigen--template-primer complex: molecular characterization by direct binding. Biochemistry. 35: 8268-74. PMID 8679582 DOI: 10.1021/Bi9530649 |
0.445 |
|
| 1996 |
Arroyo MP, Downey KM, So AG, Wangt TSF. Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase δ processivity Journal of Biological Chemistry. 271: 15971-15980. PMID 8663159 DOI: 10.1074/Jbc.271.27.15971 |
0.515 |
|
| 1996 |
Althaus IW, Chou KC, Lemay RJ, Franks KM, Deibel MR, Kezdy FJ, Resnick L, Busso ME, So AG, Downey KM, Romero DL, Thomas RC, Aristoff PA, Tarpley WG, Reusser F. The benzylthio-pyrimidine U-31,355, a potent inhibitor of HIV-1 reverse transcriptase. Biochemical Pharmacology. 51: 743-50. PMID 8602869 DOI: 10.1016/0006-2952(95)02390-9 |
0.464 |
|
| 1995 |
Downey KM, So AG. Purification of mammalian polymerases: DNA polymerase δ Methods in Enzymology. 262: 84-92. PMID 8594386 DOI: 10.1016/0076-6879(95)62011-7 |
0.647 |
|
| 1995 |
Zhang J, Tan CK, McMullen B, Downey KM, So AG. Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase δ and chromosomal location of the human gene (POLD2) Genomics. 29: 179-186. PMID 8530069 DOI: 10.1006/Geno.1995.1229 |
0.576 |
|
| 1994 |
Zhan X, Tan CK, Scott WA, Mian AM, Downey KM, So AG. Catalytically distinct conformations of the ribonuclease H of HIV-1 reverse transcriptase by substrate cleavage patterns and inhibition by azidothymidylate and N-ethylmaleimide. Biochemistry. 33: 1366-72. PMID 7508746 DOI: 10.1021/Bi00172A012 |
0.333 |
|
| 1993 |
Ng L, McConnell M, Tan CK, Downey KM, Fisher PA. Interaction of DNA polymerase δ, proliferating cell nuclear antigen, and synthetic oligonucleotide template-primers: Analysis by polyacrylamide gel electrophoresis-band mobility shift assay Journal of Biological Chemistry. 268: 13571-13576. PMID 8099910 |
0.493 |
|
| 1993 |
Dueweke TJ, Poppe SM, Romero DL, Swaney SM, So AG, Downey KM, Althaus IW, Reusser F, Busso M, Resnick L, Mayers DL, Lane J, Aristoff PA, Thomas RC, Tarpley WG. U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication Antimicrobial Agents and Chemotherapy. 37: 1127-1131. PMID 7685995 DOI: 10.1128/Aac.37.5.1127 |
0.306 |
|
| 1992 |
Thomas DC, Roberts JD, Sabatino RD, Myers TW, Tan CK, Downey KM, So AG, Bambara RA, Kunkel TA. Fidelity of mammalian DNA replication and replicative DNA polymerases. Biochemistry. 30: 11751-9. PMID 1751492 DOI: 10.1021/Bi00115A003 |
0.61 |
|
| 1992 |
So AG, Downey KM. Eukaryotic DNA replication Critical Reviews in Biochemistry and Molecular Biology. 27: 129-155. PMID 1727692 DOI: 10.3109/10409239209082561 |
0.572 |
|
| 1992 |
Li X, Tan CK, So AG, Downey KM. Purification and characterization of δ helicase from fetal calf thymus Biochemistry®. 31: 3507-3513. PMID 1313298 DOI: 10.1021/Bi00128A027 |
0.632 |
|
| 1991 |
Ng L, Tan CK, Downey KM, Fisher PA. Enzymologic mechanism of calf thymus DNA polymerase δ Journal of Biological Chemistry. 266: 11699-11704. PMID 2050671 |
0.523 |
|
| 1991 |
Chung DW, Zhang JA, Tan CK, Davie EW, So AG, Downey KM. Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. Proceedings of the National Academy of Sciences of the United States of America. 88: 11197-201. PMID 1722322 DOI: 10.1073/Pnas.88.24.11197 |
0.527 |
|
| 1991 |
Zhang J, Chung DW, Tan CK, Downey KM, Davie EW, So AG. Primary structure of the catalytic subunit of calf thymus DNA polymerase delta: sequence similarities with other DNA polymerases. Biochemistry. 30: 11742-50. PMID 1721537 DOI: 10.1021/Bi00115A002 |
0.584 |
|
| 1991 |
Tan CK, Civil R, Mohsin Mian A, So AG, Downey KM. Inhibition of the RNase H activity of HIV reverse transcriptase by azidothymidylate Biochemistry. 30: 4831-4835. PMID 1709809 |
0.407 |
|
| 1991 |
Tan CK, Zhang J, Li ZY, Tarpley WG, Downey KM, So AG. Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase Biochemistry®. 30: 2651-2655. PMID 1705816 DOI: 10.1021/Bi00224A013 |
0.533 |
|
| 1990 |
Downey KM, Tan C‐, So AG. DNA polymerase delta: A second eukaryotic DNA replicase Bioessays. 12: 231-236. PMID 2196053 DOI: 10.1002/Bies.950120507 |
0.609 |
|
| 1989 |
Wong SW, Syvaoja J, Tan CK, Downey KM, So AG, Linn S, Wang TSF. DNA polymerases α and δ are immunologically and structurally distinct Journal of Biological Chemistry. 264: 5924-5928. PMID 2466832 |
0.488 |
|
| 1988 |
El-Deiry WS, So AG, Downey KM. Mechanisms of error discrimination by Escherichia coli DNA polymerase I Biochemistry. 27: 546-553. PMID 3280024 DOI: 10.1021/Bi00402A007 |
0.578 |
|
| 1988 |
So AG, Downey KM. Mammalian DNA polymerases α and δ: Current status in DNA replication Biochemistry. 27: 4591-4595. PMID 3048386 DOI: 10.1021/Bi00413A001 |
0.564 |
|
| 1987 |
Tan CK, So MJ, Downey KM, So AG. Apparent stimulation of calf thymus DNA polymerase alpha by ATP Nucleic Acids Research. 15: 2269-2278. PMID 3562228 DOI: 10.1093/Nar/15.5.2269 |
0.527 |
|
| 1987 |
Tan CK, Sullivan K, Li X, Tan EM, Downey KM, So AG. Autoantibody to the proliferating cell nuclear antigen neutralizes the activity of the auxiliary protein for DNA polymerase delta Nucleic Acids Research. 15: 9299-9308. PMID 2891114 DOI: 10.1093/Nar/15.22.9299 |
0.426 |
|
| 1987 |
Prelich G, Tan CK, Kostura M, Mathews MB, So AG, Downey KM, Stillman B. Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein Nature. 326: 517-520. PMID 2882424 DOI: 10.1038/326517A0 |
0.583 |
|
| 1986 |
Cheng-Keat Tan, Castillo C, So AG, Downey KM. An auxiliary protein for DNA polymerase-δ from fetal calf thymus Journal of Biological Chemistry. 261: 12310-12316. PMID 3745189 |
0.561 |
|
| 1984 |
Patten JE, So AG, Downey KM. Effect of base-pair stability of nearest-neighbor nucleotides on the fidelity of deoxyribonucleic acid synthesis Biochemistry. 23: 1613-1618. PMID 6722115 DOI: 10.1021/Bi00303A005 |
0.388 |
|
| 1984 |
Lee MYWT, Tan CK, Downey KM, So AG. Further studies on calf thymus DNA polymerase δ purified to homogeneity by a new procedure Biochemistry. 23: 1906-1913. PMID 6426510 DOI: 10.1021/Bi00304A003 |
0.635 |
|
| 1984 |
El-Deiry WS, Downey KM, So AG. Molecular mechanisms of manganese mutagenesis Proceedings of the National Academy of Sciences of the United States of America. 81: 7378-7382. PMID 6095289 DOI: 10.1073/Pnas.81.23.7378 |
0.511 |
|
| 1983 |
Murray TR, Downey KM, Yunis AA. Chloramphenicol-mediated DNA damage and its possible role in the inhibitory effects of chloramphenicol on DNA synthesis The Journal of Laboratory and Clinical Medicine. 102: 926-932. PMID 6644156 |
0.55 |
|
| 1982 |
Murray T, Downey KM, Yunis AA. Degradation of isolated deoxyribonucleic acid mediated by nitroso-chloramphenicol. Possible role in chloramphenicol-induced aplastic anemia Biochemical Pharmacology. 31: 2291-2296. PMID 7126241 DOI: 10.1016/0006-2952(82)90117-4 |
0.533 |
|
| 1981 |
Tsang Lee MYW, Tan CK, Downey KM, So AG. Structural and Functional Properties of Calf Thymus DNA Polymerase δ Progress in Nucleic Acid Research and Molecular Biology. 26: 83-96. PMID 7280266 DOI: 10.1016/S0079-6603(08)60396-7 |
0.627 |
|
| 1980 |
Que BG, Downey KM, So AG. Degradation of deoxyribonucleic acid by a 1,10-phenanthroline-copper complex: The role of hydroxyl radicals Biochemistry. 19: 5987-5991. PMID 7470443 DOI: 10.1021/Bi00567A007 |
0.44 |
|
| 1980 |
Tsang Lee MYW, Tan CK, So AG, Downey KM. Purification of Deoxyribonucleic Acid polymerase δ from calf thymus: Partial characterization of physical properties Biochemistry. 19: 2096-2101. PMID 7378348 DOI: 10.1021/Bi00551A015 |
0.579 |
|
| 1980 |
Downey KM, Que BG, So AG. Degradation of DNA by 1,-10-phenanthroline Biochemical and Biophysical Research Communications. 93: 264-270. PMID 6445734 DOI: 10.1016/S0006-291X(80)80275-0 |
0.573 |
|
| 1980 |
Lee MY, Byrnes JJ, Downey KM, So AG. Mechanism of inhibition of deoxyribonucleic acid synthesis by 1-beta-D-arabinofuranosyladenosine triphosphate and its potentiation by 6-mercaptopurine ribonucleoside 5'-monophosphate. Biochemistry. 19: 215-9. PMID 6153266 DOI: 10.1021/Bi00542A032 |
0.573 |
|
| 1979 |
Que BG, Downey KM, So AG. Selective inhibition of the polymerase activity of DNA polymerase I. Further evidence for separate active sites for polymerase and 3′ to 5′ exonuclease activities Biochemistry. 18: 2064-2068. PMID 373799 DOI: 10.1021/Bi00577A034 |
0.543 |
|
| 1979 |
Que BG, So AG, Downey KM. Selective inhibition of the polymerase activity of DNA polymerase I by 1,10-phenanthroline Federation Proceedings. 38. |
0.514 |
|
| 1978 |
Que BG, Downey KM, So AG. Mechanism of selective inhibition of 3′ to 5′ exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5′-monophosphates Biochemistry. 17: 1603-1606. PMID 350269 DOI: 10.1021/Bi00602A004 |
0.498 |
|
| 1978 |
Lee MYW, Byrnes JJ, Downey KM, So AG. Mechanism of inhibition of DNA synthesis by 1-β-D-arabinofuranosyl ATP and its potentiation by 6-mercaptopurine ribonucleoside 5'-monophosphate Federation Proceedings. 37. |
0.369 |
|
| 1977 |
Byrnes JJ, Downey KM, Que BG, Lee MY, Black VL, So AG. Selective inhibition of the 3' to 5' exonuclease activity associated with DNA polymerases: a mechanism of mutagenesis. Biochemistry. 16: 3740-6. PMID 332220 DOI: 10.1021/Bi00636A002 |
0.543 |
|
| 1976 |
Byrnes JJ, Downey KM, Black VL, So AG. A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta. Biochemistry. 15: 2817-23. PMID 949478 DOI: 10.1021/Bi00658A018 |
0.628 |
|
| 1975 |
Byrnes JJ, Downey KM, Esserman L, So AG. Mechanism of hemin inhibition of erythroid cytoplasmic DNA polymerase. Biochemistry. 14: 796-9. PMID 1115772 DOI: 10.1021/Bi00675A023 |
0.624 |
|
| 1974 |
Byrnes JJ, Downey KM, Jurmark BS, So AG. Reticulocyte DNA polymerase. Nature. 248: 687-90. PMID 4833272 DOI: 10.1038/248687A0 |
0.616 |
|
| 1974 |
Downey KM, Byrnes JJ, Jurmark BS, So AG. The effect of 6-mercaptopurine and its derivatives on mammalian RNA-dependent RNA synthesis. Biochemical and Biophysical Research Communications. 56: 227-33. PMID 4823440 DOI: 10.1016/S0006-291X(74)80338-4 |
0.322 |
|
| 1974 |
Byrnes JJ, Downey KM, So AG. Metabolic regulation of cytoplasmic DNA synthesis. Proceedings of the National Academy of Sciences of the United States of America. 71: 205-8. PMID 4521051 DOI: 10.1073/Pnas.71.1.205 |
0.54 |
|
| 1973 |
Downey KM, Byrnes JJ, Jurmark BS, So AG. Reticulocyte RNA-dependent RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 70: 3400-4. PMID 4519633 DOI: 10.1073/Pnas.70.12.3400 |
0.345 |
|
| 1971 |
Downey KM, Jurmark BS, So AG. Determination of nucleotide sequences at promoter regions by the use of dinucleotides Biochemistry. 10: 4970-4975. PMID 4944064 DOI: 10.1021/Bi00802A021 |
0.464 |
|
| 1970 |
Downey KM, So AG. Studies on the kinetics of ribonucleic acid chain initiation and elongation Biochemistry. 9: 2520-2525. PMID 4912487 DOI: 10.1021/Bi00814A019 |
0.34 |
|
| 1970 |
So AG, Downey KM. Studies on the mechanism of ribonucleic acid synthesis. II. Stabilization of the deoxyribonucleic acid-ribonucleic acid polymerase complex by the formation of a single phosphodiester bond Biochemistry. 9: 4787-4793. PMID 4320541 DOI: 10.1021/Bi00826A024 |
0.453 |
|
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