Thomas I. Michalak - Publications

Affiliations: 
Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada 
Area:
Immunology, Cell Biology

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Michalak TI. Diverse Virus and Host-Dependent Mechanisms Influence the Systemic and Intrahepatic Immune Responses in the Woodchuck Model of Hepatitis B. Frontiers in Immunology. 11: 853. PMID 32536912 DOI: 10.3389/fimmu.2020.00853  0.593
2020 Liu LY, Ma XZ, Ouyang B, Ings DP, Marwah S, Liu J, Chen AY, Gupta R, Manuel J, Chen XC, Gage BK, Cirlan I, Khuu N, Chung S, Camat D, ... ... Michalak TI, et al. Nanoparticle Uptake in a Spontaneous and Immunocompetent Woodchuck Liver Cancer Model. Acs Nano. PMID 32255624 DOI: 10.1021/Acsnano.0C00468  0.395
2020 Chauhan R, Michalak TI. Kinetics of DNA damage repair response accompanying initial hepadnavirus-host genomic integration in woodchuck hepatitis virus infection of hepatocyte. Cancer Genetics. 244: 1-10. PMID 32062411 DOI: 10.1016/j.cancergen.2020.02.001  0.311
2019 Coffin CS, Ramji A, Cooper CL, Miles D, Doucette KE, Wong P, Tam E, Wong DK, Wong A, Ukabam S, Bailey RJ, Tsoi K, Conway B, Barrett L, Michalak TI, et al. Epidemiologic and clinical features of chronic hepatitis B virus infection in 8 Canadian provinces: a descriptive study by the Canadian HBV Network. Cmaj Open. 7: E610-E617. PMID 31641059 DOI: 10.9778/cmajo.20190103  0.571
2019 Chauhan R, Shimizu Y, Watashi K, Wakita T, Fukasawa M, Michalak TI. Retrotransposon elements among initial sites of hepatitis B virus integration into human genome in the HepG2-NTCP cell infection model. Cancer Genetics. PMID 31064734 DOI: 10.1016/j.cancergen.2019.04.060  0.459
2018 Williams JB, Hüppner A, Mulrooney-Cousins PM, Michalak TI. Differential Expression of Woodchuck Toll-Like Receptors 1-10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection. Frontiers in Microbiology. 9: 3007. PMID 30581424 DOI: 10.3389/fmicb.2018.03007  0.563
2018 Chauhan R, Lingala S, Gadiparthi C, Lahiri N, Mohanty SR, Wu J, Michalak TI, Satapathy SK. Reactivation of hepatitis B after liver transplantation: Current knowledge, molecular mechanisms and implications in management. World Journal of Hepatology. 10: 352-370. PMID 29599899 DOI: 10.4254/Wjh.V10.I3.352  0.531
2017 Skardasi G, Chen AY, Michalak TI. Authentic Patient-Derived Hepatitis C Virus Infects and Productively Replicates in Primary CD4+ and CD8+ T Lymphocytes In Vitro. Journal of Virology. PMID 29167333 DOI: 10.1128/JVI.01790-17  0.379
2017 Chauhan R, Churchill ND, Mulrooney-Cousins PM, Michalak TI. Initial sites of hepadnavirus integration into host genome in human hepatocytes and in the woodchuck model of hepatitis B-associated hepatocellular carcinoma. Oncogenesis. 6: e317. PMID 28414318 DOI: 10.1038/oncsis.2017.22  0.453
2015 Mulrooney-Cousins PM, Michalak TI. Asymptomatic Hepadnaviral Persistence and Its Consequences in the Woodchuck Model of Occult Hepatitis B Virus Infection. Journal of Clinical and Translational Hepatology. 3: 211-9. PMID 26623268 DOI: 10.14218/JCTH.2015.00020  0.621
2015 Chen AY, Hoare M, Shankar AN, Allison M, Alexander GJ, Michalak TI. Persistence of Hepatitis C Virus Traces after Spontaneous Resolution of Hepatitis C. Plos One. 10: e0140312. PMID 26473969 DOI: 10.1371/journal.pone.0140312  0.371
2015 Dai B, Chen AY, Corkum CP, Peroutka RJ, Landon A, Houng S, Muniandy PA, Zhang Y, Lehrmann E, Mazan-Mamczarz K, Steinhardt J, Shlyak M, Chen QC, Becker KG, Livak F, ... Michalak TI, et al. Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. PMID 26434584 DOI: 10.1038/Onc.2015.364  0.388
2015 MacParland SA, Chen AY, Corkum CP, Pham TN, Michalak TI. Patient-derived hepatitis C virus inhibits CD4(+) but not CD8(+) T lymphocyte proliferation in primary T cells. Virology Journal. 12: 93. PMID 26084511 DOI: 10.1186/s12985-015-0322-4  0.385
2015 MacParland SA, Corkum CP, Burgess C, Karwowska S, Kroll W, Michalak TI. Differential expression of interferon alpha inducible genes in peripheral blood mononuclear cells from patients chronically infected with hepatitis C virus and healthy donors. International Immunopharmacology. 25: 545-52. PMID 25765354 DOI: 10.1016/j.intimp.2015.02.037  0.481
2014 Mulrooney-Cousins PM, Chauhan R, Churchill ND, Michalak TI. Primary seronegative but molecularly evident hepadnaviral infection engages liver and induces hepatocarcinoma in the woodchuck model of hepatitis B. Plos Pathogens. 10: e1004332. PMID 25165821 DOI: 10.1371/journal.ppat.1004332  0.586
2014 Coffin CS, Mulrooney-Cousins PM, Osiowy C, van der Meer F, Nishikawa S, Michalak TI, van Marle G, Gill MJ. Virological characteristics of occult hepatitis B virus in a North American cohort of human immunodeficiency virus type 1-positive patients on dual active anti-HBV/HIV therapy. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 60: 347-53. PMID 24881491 DOI: 10.1016/j.jcv.2014.04.021  0.482
2014 Chen A, Hoare M, Alexander G, Michalak T. P716 PERSISTENCE OF HEPATITIS C VIRUS AFTER SPONTANEOUS RECOVERY FROM HEPATITIS C Journal of Hepatology. 60: S308. DOI: 10.1016/S0168-8278(14)60878-3  0.441
2014 Mulrooney-Cousins P, Chauhan R, Churchill N, Michalak T. P171 PRIMARY SERONEGATIVE HEPADNAVIRAL INFECTION ENGAGES LIVER OVER TIME AND INDUCES HEPATOCELLULAR CARCINOMA IN WOODCHUCK HEPATITIS B MODEL Journal of Hepatology. 60: S123. DOI: 10.1016/S0168-8278(14)60333-0  0.482
2013 Chen AY, Zeremski M, Chauhan R, Jacobson IM, Talal AH, Michalak TI. Persistence of hepatitis C virus during and after otherwise clinically successful treatment of chronic hepatitis C with standard pegylated interferon α-2b and ribavirin therapy. Plos One. 8: e80078. PMID 24278242 DOI: 10.1371/journal.pone.0080078  0.451
2013 Sugden PB, Pham TN, Ratnarajah S, Cameron B, Bull R, White PA, Michalak TI, Lloyd AR. Rare occurrence of occult hepatitis C virus in apparently uninfected injecting drug users: a two-centre, masked, case-control study. Journal of Viral Hepatitis. 20: 725-8. PMID 24010647 DOI: 10.1111/jvh.12098  0.324
2013 Sarhan MA, Chen AY, Michalak TI. Differential expression of candidate virus receptors in human T lymphocytes prone or resistant to infection with patient-derived hepatitis C virus. Plos One. 8: e62159. PMID 23626783 DOI: 10.1371/journal.pone.0062159  0.393
2013 Pham TN, Lin DM, Mulrooney-Cousins PM, Churchill ND, Kowala-Piaskowska A, Mozer-Lisewska I, Machaj A, Pazgan-Simon M, Zalewska M, Simon K, King D, Reddy SB, Michalak TI. Hepatitis C virus load and expression of a unique subset of cellular genes in circulating lymphoid cells differentiate non-responders from responders to pegylated interferon alpha-ribavirin treatment. Journal of Medical Virology. 85: 441-8. PMID 23280583 DOI: 10.1002/jmv.23481  0.384
2013 Chen A, Zeremski M, Jacobson I, Talal A, Michalak T. 477 PERSISTENCE OF HEPATITIS C VIRUS DURING AND AFTER CLINICALLY APPARENT SUCCESSFUL TREATMENT OF CHRONIC HEPATITIS C Journal of Hepatology. 58: S195-S196. DOI: 10.1016/S0168-8278(13)60479-1  0.473
2012 Gujar SA, Mulrooney-Cousins PM, Michalak TI. Repeated exposure to trace amounts of woodchuck hepadnavirus induces molecularly evident infection and virus-specific T cell response in the absence of serological infection markers and hepatitis. Journal of Virology. 87: 1035-48. PMID 23135718 DOI: 10.1128/JVI.01363-12  0.554
2012 Sarhan MA, Chen AY, Russell RS, Michalak TI. Patient-derived hepatitis C virus and JFH-1 clones differ in their ability to infect human hepatoma cells and lymphocytes. The Journal of General Virology. 93: 2399-407. PMID 22855787 DOI: 10.1099/vir.0.045393-0  0.413
2012 Sarhan MA, Pham TN, Chen AY, Michalak TI. Hepatitis C virus infection of human T lymphocytes is mediated by CD5. Journal of Virology. 86: 3723-35. PMID 22278227 DOI: 10.1128/JVI.06956-11  0.39
2012 Pham TN, Coffin CS, Churchill ND, Urbanski SJ, Lee SS, Michalak TI. Hepatitis C virus persistence after sustained virological response to antiviral therapy in patients with or without past exposure to hepatitis B virus. Journal of Viral Hepatitis. 19: 103-11. PMID 21699630 DOI: 10.1111/j.1365-2893.2011.01442.x  0.481
2011 Pham TN, Michalak TI. Occult hepatitis C virus infection and its relevance in clinical practice. Journal of Clinical and Experimental Hepatology. 1: 185-9. PMID 25755384 DOI: 10.1016/S0973-6883(11)60130-8  0.462
2011 Coffin CS, Mulrooney-Cousins PM, van Marle G, Roberts JP, Michalak TI, Terrault NA. Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 17: 955-62. PMID 21462295 DOI: 10.1002/lt.22312  0.489
2011 Coffin C, Mulrooney-Cousins P, van der Meer F, Nisikawa S, Michalak T, Gill M, van Marie G. 1105 LONG-TERM FOLLOW-UP OF OCCULT HBV QUASISPECIES DIVERSITY AND LYMPHOTROPISM IN HIV-1-INFECTED PATIENTS REACTIVE FOR ANTIBODY TO HBV CORE ANTIGEN (ANTI-HBC) Journal of Hepatology. 54: S438. DOI: 10.1016/S0168-8278(11)61107-0  0.314
2011 Pham T, Lin D, Mulrooney-Cousins P, Churchill N, Kowala-Piaskowska A, Mozer-Lisewska I, Machaj A, Pazgan-Simon M, Zalewska M, Simon K, King D, Reddy S, Michalak T. 462 HEPATITIS C VIRUS LOAD AND EXPRESSION OF A UNIQUE SUBSET OF CELLULAR GENES IN LYMPHOID CELLS DIFFERENTIATE NONRESPONDERS FROM RESPONDERS TO PEGYLATED INTERFERON ALPHA-RIBAVIRIN TREATME Journal of Hepatology. 54: S188. DOI: 10.1016/S0168-8278(11)60464-9  0.402
2010 Lin LT, Noyce RS, Pham TN, Wilson JA, Sisson GR, Michalak TI, Mossman KL, Richardson CD. Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific microRNA 122. Journal of Virology. 84: 9170-80. PMID 20592082 DOI: 10.1128/Jvi.00559-10  0.474
2010 Michalak TI. Immune cell reservoirs of persisting hepatitis C virus. Gut. 59: 867-8. PMID 20581230 DOI: 10.1136/gut.2010.210054  0.452
2010 Gujar SA, Jenkins AK, Macparland SA, Michalak TI. Pre-acute hepadnaviral infection is associated with activation-induced apoptotic death of lymphocytes in the woodchuck (Marmota monax) model of hepatitis B. Developmental and Comparative Immunology. 34: 999-1008. PMID 20451550 DOI: 10.1016/j.dci.2010.05.001  0.465
2010 Pham TNQ, Coffin CS, Michalak TI. Occult hepatitis C virus infection: What does it mean? Liver International. 30: 502-511. PMID 20070513 DOI: 10.1111/j.1478-3231.2009.02193.x  0.49
2009 Michalak TI, Zhang H, Churchill ND, Larsson T, Johansson NG, Oberg B. Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis B. Antimicrobial Agents and Chemotherapy. 53: 3803-14. PMID 19564357 DOI: 10.1128/AAC.00263-09  0.456
2009 Pachiadakis I, Chokshi S, Cooksley H, Farmakiotis D, Sarrazin C, Zeuzem S, Michalak TI, Naoumov NV. Early viraemia clearance during antiviral therapy of chronic hepatitis C improves dendritic cell functions. Clinical Immunology (Orlando, Fla.). 131: 415-25. PMID 19303818 DOI: 10.1016/j.clim.2009.02.001  0.311
2009 Pham TN, Mercer SE, Michalak TI. Chronic hepatitis C and persistent occult hepatitis C virus infection are characterized by distinct immune cell cytokine expression profiles. Journal of Viral Hepatitis. 16: 547-56. PMID 19215578 DOI: 10.1111/j.1365-2893.2009.01092.x  0.425
2009 Gujar SA, Michalak TI. Primary occult hepadnavirus infection induces virus-specific T-cell and aberrant cytokine responses in the absence of antiviral antibody reactivity in the Woodchuck model of hepatitis B virus infection. Journal of Virology. 83: 3861-76. PMID 19193791 DOI: 10.1128/JVI.02521-08  0.554
2009 MacParland SA, Pham TN, Guy CS, Michalak TI. Hepatitis C virus persisting after clinically apparent sustained virological response to antiviral therapy retains infectivity in vitro. Hepatology (Baltimore, Md.). 49: 1431-41. PMID 19177592 DOI: 10.1002/hep.22802  0.39
2009 Guy C, Wang J, Michalak T. 119 HEPATOCYTES AS CYTOTOXIC EFFECTOR CELLS AND THEIR CELL KILLING ACTIVITY DURING PROGRESSION AND RECOVERY FROM HEPADNAVIRUAL HEPATITIS Journal of Hepatology. 50: S48-S49. DOI: 10.1016/S0168-8278(09)60121-5  0.498
2008 Raimondo G, Allain JP, Brunetto MR, Buendia MA, Chen DS, Colombo M, Craxì A, Donato F, Ferrari C, Gaeta GB, Gerlich WH, Levrero M, Locarnini S, Michalak T, Mondelli MU, et al. Statements from the Taormina expert meeting on occult hepatitis B virus infection. Journal of Hepatology. 49: 652-7. PMID 18715666 DOI: 10.1016/j.jhep.2008.07.014  0.53
2008 Guy CS, Mulrooney-Cousins PM, Churchill ND, Michalak TI. Intrahepatic expression of genes affiliated with innate and adaptive immune responses immediately after invasion and during acute infection with woodchuck hepadnavirus. Journal of Virology. 82: 8579-91. PMID 18596101 DOI: 10.1128/JVI.01022-08  0.603
2008 Pham TN, Michalak TI. Hepatitis C virus in peripheral blood mononuclear cells of individuals with isolated anti-hepatitis C virus antibody reactivity. Hepatology (Baltimore, Md.). 48: 350-1; author reply . PMID 18537176 DOI: 10.1002/hep.22384  0.439
2008 Mulrooney-Cousins PM, Michalak TI. Repeated passage of wild-type woodchuck hepatitis virus in lymphoid cells does not generate cell type-specific variants or alter virus infectivity. Journal of Virology. 82: 7540-50. PMID 18495768 DOI: 10.1128/JVI.00405-08  0.479
2008 Gujar SA, Jenkins AK, Guy CS, Wang J, Michalak TI. Aberrant lymphocyte activation precedes delayed virus-specific T-cell response after both primary infection and secondary exposure to hepadnavirus in the woodchuck model of hepatitis B virus infection. Journal of Virology. 82: 6992-7008. PMID 18480439 DOI: 10.1128/JVI.00661-08  0.484
2008 Guy CS, Rankin SL, Wang J, Michalak TI. Hepatocytes can induce death of contacted cells via perforin-dependent mechanism. Hepatology (Baltimore, Md.). 47: 1691-701. PMID 18393317 DOI: 10.1002/hep.22228  0.365
2008 Mulrooney-Cousins PM, Michalak TI. Persistent occult hepatitis B virus infection: experimental findings and clinical implications. World Journal of Gastroenterology. 13: 5682-6. PMID 17963292 DOI: 10.3748/WJG.V13.I43.5682  0.553
2008 Pham T, Mercer S, Michalak T. 616 DIFFERENT IMMUNE CELL CYTOKINE EXPRESSION PROFILES CHARACTERIZE CHRONIC HEPATITIS C AND OCCULT HEPATITIS C VIRUS INFECTION Journal of Hepatology. 48: S229-S230. DOI: 10.1016/S0168-8278(08)60618-2  0.561
2007 Pham TN, King D, Macparland SA, McGrath JS, Reddy SB, Bursey FR, Michalak TI. Hepatitis C virus replicates in the same immune cell subsets in chronic hepatitis C and occult infection. Gastroenterology. 134: 812-22. PMID 18243182 DOI: 10.1053/j.gastro.2007.12.011  0.536
2007 Pham TN, Mulrooney-Cousins PM, Mercer SE, MacParland SA, Inglot M, Zalewska M, Simon K, Michalak TI. Antagonistic expression of hepatitis C virus and alpha interferon in lymphoid cells during persistent occult infection. Journal of Viral Hepatitis. 14: 537-48. PMID 17650287 DOI: 10.1111/j.1365-2893.2006.00834.x  0.505
2007 Coffin CS, Mulrooney-Cousins PM, Lee SS, Michalak TI, Swain MG. Profound suppression of chronic hepatitis C following superinfection with hepatitis B virus. Liver International : Official Journal of the International Association For the Study of the Liver. 27: 722-6. PMID 17498260 DOI: 10.1111/J.1478-3231.2007.01477.X  0.585
2007 Michalak TI, Pham TN, Mulrooney-Cousins PM. Molecular diagnosis of occult HCV and HBV infections Future Virology. 2: 451-465. DOI: 10.2217/17460794.2.5.451  0.377
2007 Pachiadakis I, Choksi S, Cooksley H, Sarrazzin C, Zeuzem S, Michalak T, Naoumov N. [457] HCV INFECTION OF DENDRITIC CELLS AFFECTS THEIR FUNCTION LEADING TO AN IMPAIRED ADAPTIVE IMMUNE RESPONSE Journal of Hepatology. 46: S174. DOI: 10.1016/S0168-8278(07)62055-8  0.315
2007 Priam T, Michalak T. [437] THE SAME IMMUNE CELL SUBSETS SUPPORT HEPATITIS C VIRUS REPLICATION IN BOTH CHRONIC HEPATITIS C AND OCCULT HCV INFECTION Journal of Hepatology. 46: S167. DOI: 10.1016/S0168-8278(07)62035-2  0.531
2007 Gujar S, Michalak T. [409] REPEATED EXPOSURE TO SMALL DOSES OF HEPADNAVIRUS DOES NOT INDUCE HEPATITIS BUT CAUSES PROMINENT VIRUS-SPECIFIC T CELL RESPONSES IN THE ABSENCE OF HUMORAL IMMUNITY Journal of Hepatology. 46: S157-S158. DOI: 10.1016/S0168-8278(07)62007-8  0.374
2007 Gujar S, Michalak T. [402] BOTH PRIMARY OCCULT AND SEROLOGICALLY EVIDENT HEPADNAVIRUS INFECTIONS INDUCE SIMILAR PROFILES OF VIRUS-SPECIFIC AND MITOGEN-INDUCED T CELL RESPONSES Journal of Hepatology. 46: S155. DOI: 10.1016/S0168-8278(07)62000-5  0.346
2006 MacParland SA, Pham TNQ, Gujar SA, Michalak TI. De novo infection and propagation of wild-type Hepatitis C virus in human T lymphocytes in vitro. The Journal of General Virology. 87: 3577-3586. PMID 17098973 DOI: 10.1099/VIR.0.81868-0  0.39
2006 Wang J, Gujar SA, Cova L, Michalak TI. Bicistronic woodchuck hepatitis virus core and gamma interferon DNA vaccine can protect from hepatitis but does not elicit sterilizing antiviral immunity. Journal of Virology. 81: 903-16. PMID 17079319 DOI: 10.1128/JVI.01537-06  0.435
2006 Wang J, Michalak TI. Inhibition by woodchuck hepatitis virus of class I major histocompatibility complex presentation on hepatocytes is mediated by virus envelope pre-S2 protein and can be reversed by treatment with gamma interferon. Journal of Virology. 80: 8541-53. PMID 16912304 DOI: 10.1128/JVI.00830-06  0.4
2006 Guy CS, Wang J, Michalak TI. Hepatocytes as cytotoxic effector cells can induce cell death by CD95 ligand-mediated pathway. Hepatology (Baltimore, Md.). 43: 1231-40. PMID 16729304 DOI: 10.1002/hep.21201  0.334
2006 Gujar SA, Michalak TI. Characterization of bioactive recombinant woodchuck interleukin-2 amplified by RLM-RACE and produced in eukaryotic expression system. Veterinary Immunology and Immunopathology. 112: 183-98. PMID 16631932 DOI: 10.1016/J.VETIMM.2006.02.011  0.481
2006 Pham T, MacParland S, Michalak T. P.196 Occult persistence of hepatitis C virus Journal of Clinical Virology. 36: S121. DOI: 10.1016/S1386-6532(06)80376-8  0.418
2006 Coffin C, Pharn T, Urbanski S, Michalak T, Lee S. 527 Persistent hepatic alterations in individuals with occult HCV infection following sustained virological response to antiviral therapy Journal of Hepatology. 44: S196. DOI: 10.1016/S0168-8278(06)80527-1  0.403
2006 Pham T, Michalak T. 410 Modifying effect of hepatitis C virus (HCV) load in naive lymphoid cells on the detection of occult HCV infection following stimulation of the cells with mitogens Journal of Hepatology. 44: S154-S155. DOI: 10.1016/S0168-8278(06)80410-1  0.422
2005 Pham TNQ, MacParland SA, Coffin CS, Lee SS, Bursey FR, Michalak TI. Mitogen-induced upregulation of hepatitis C virus expression in human lymphoid cells. The Journal of General Virology. 86: 657-666. PMID 15722526 DOI: 10.1099/VIR.0.80624-0  0.401
2005 Gujar SA, Michalak TI. Flow Cytometric Quantification of T Cell Proliferation and Division Kinetics in Woodchuck Model of Hepatitis B Immunological Investigations. 34: 215-236. DOI: 10.1081/IMM-55834  0.368
2004 Coffin CS, Pham TN, Mulrooney PM, Churchill ND, Michalak TI. Persistence of isolated antibodies to woodchuck hepatitis virus core antigen is indicative of occult infection. Hepatology (Baltimore, Md.). 40: 1053-61. PMID 15382154 DOI: 10.1002/hep.20419  0.538
2004 Pham TN, MacParland SA, Mulrooney PM, Cooksley H, Naoumov NV, Michalak TI. Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C. Journal of Virology. 78: 5867-74. PMID 15140984 DOI: 10.1128/JVI.78.11.5867-5874.2004  0.37
2004 Churchill ND, Michalak TI. Woodchuck hepatitis virus hepatocyte culture models. Methods in Molecular Medicine. 96: 175-87. PMID 14762269 DOI: 10.1385/1-59259-670-3:175  0.449
2004 Michalak TI, Mulrooney PM, Coffin CS. Low Doses of Hepadnavirus Induce Infection of the Lymphatic System That Does Not Engage the Liver Journal of Virology. 78: 1730-1738. PMID 14747538 DOI: 10.1128/JVI.78.4.1730-1738.2004  0.585
2004 Pham T, MacParland S, Michalak T. 411 Upregulation of HCV RNA by mitogen stimulation in lymphoid cells from patients with chronic hepatitis C Journal of Hepatology. 40: 122. DOI: 10.1016/S0168-8278(04)90411-4  0.389
2004 Mulrooney P, Coffin C, Michalak T. 39 Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver Journal of Hepatology. 40: 15. DOI: 10.1016/S0168-8278(04)90039-6  0.395
2003 Diao J, Slaney DM, Michalak TI. Modulation of the outcome and severity of hepadnaviral hepatitis in woodchucks by antibodies to hepatic asialoglycoprotein receptor Hepatology. 38: 629-638. PMID 12939589 DOI: 10.1053/jhep.2003.50370  0.656
2003 Mulrooney PM, Michalak TI. Quantitative detection of hepadnavirus-infected lymphoid cells by in situ PCR combined with flow cytometry: implications for the study of occult virus persistence. Journal of Virology. 77: 970-9. PMID 12502813 DOI: 10.1128/JVI.77.2.970-979.2003  0.447
2001 Hodgson PD, Michalak TI. Augmented hepatic interferon gamma expression and T-cell influx characterize acute hepatitis progressing to recovery and residual lifelong virus persistence in experimental adult woodchuck hepatitis virus infection. Hepatology (Baltimore, Md.). 34: 1049-59. PMID 11679978 DOI: 10.1053/Jhep.2001.29004  0.711
2001 Lew YY, Michalak TI. In vitro and in vivo infectivity and pathogenicity of the lymphoid cell-derived woodchuck hepatitis virus. Journal of Virology. 75: 1770-82. PMID 11160675 DOI: 10.1128/JVI.75.4.1770-1782.2001  0.532
2001 Michalak T, Hodgson P, Churchill N. Autoantibodies to asialoglycoprotein receptor and their relevance to liver function and injury in the woodchuck model of hepatitis B Journal of Hepatology. 34: 206. DOI: 10.1016/S0168-8278(01)81637-8  0.658
2001 Michalak T, Hodgson P, Churchill N. Inhibition of class I MHC presentation on hepatocytes and lymphoid cells in chronic viral hepatitis in woodchucks Journal of Hepatology. 34: 112. DOI: 10.1016/S0168-8278(01)81277-0  0.711
2000 Michalak TI. Occult persistence and lymphotropism of hepadnaviral infection: insights from the woodchuck viral hepatitis model. Immunological Reviews. 174: 98-111. PMID 10807510 DOI: 10.1034/j.1600-0528.2002.017406.x  0.594
2000 Michalak TI, Hodgson PD, Churchill ND. Posttranscriptional inhibition of class I major histocompatibility complex presentation on hepatocytes and lymphoid cells in chronic woodchuck hepatitis virus infection. Journal of Virology. 74: 4483-94. PMID 10775584 DOI: 10.1128/Jvi.74.10.4483-4494.2000  0.732
1999 Hodgson PD, Grant MD, Michalak TI. Perforin and Fas/Fas ligand-mediated cytotoxicity in acute and chronic woodchuck viral hepatitis. Clinical and Experimental Immunology. 118: 63-70. PMID 10540161  0.706
1999 Coffin CS, Michalak TI. Persistence of infectious hepadnavirus in the offspring of woodchuck mothers recovered from viral hepatitis Journal of Clinical Investigation. 104: 203-212. PMID 10411550 DOI: 10.1172/JCI5048  0.564
1999 Michalak TI, Pardoe IU, Coffin CS, Churchill ND, Freake DS, Smith P, Trelegan CL. Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis. Hepatology (Baltimore, Md.). 29: 928-38. PMID 10051500 DOI: 10.1002/HEP.510290329  0.636
1998 Diao J, Churchill ND, Michalak TI. Complement-mediated cytotoxicity and inhibition of ligand binding to hepatocytes by woodchuck hepatitis virus-induced autoantibodies to asialoglycoprotein receptor Hepatology. 27: 1623-1631. PMID 9620336 DOI: 10.1002/hep.510270623  0.477
1997 Diao J, Michalak TI. Virus-induced anti-asialoglycoprotein receptor autoimmunity in experimental hepadnaviral hepatitis Hepatology. 25: 689-696. PMID 9049220 DOI: 10.1002/hep.510250333  0.567
1996 Jin YM, Churchill ND, Michalak TI. Protease-activated lymphoid cell and hepatocyte recognition site in the preS1 domain of the large woodchuck hepatitis virus envelope protein. The Journal of General Virology. 1837-46. PMID 8760435 DOI: 10.1099/0022-1317-77-8-1837  0.32
1995 Michalak TI, Lau JY, McFarlane BM, Alexander GJ, Eddleston AL, Williams R. Antibody-directed complement-mediated cytotoxicity to hepatocytes from patients with chronic hepatitis B. Clinical and Experimental Immunology. 100: 227-32. PMID 7743660 DOI: 10.1111/j.1365-2249.1995.tb03658.x  0.577
1995 Michalak TI, Churchill ND, Codner D, Drover S, Marshall WH. Identification of woodchuck class I MHC antigens using monoclonal antibodies. Tissue Antigens. 45: 333-42. PMID 7652741 DOI: 10.1111/J.1399-0039.1995.TB02463.X  0.389
1994 Michalak TI, Pasquinelli C, Guilhot S, Chisari FV. Hepatitis B virus persistence after recovery from acute viral hepatitis. The Journal of Clinical Investigation. 93: 230-9. PMID 8282792 DOI: 10.1172/Jci116950  0.55
1994 Michalak TI, Pasquinelli C, Guilhot S, Chisari FV. Hepatitis B virus persistence after recovery from acute viral hepatitis Journal of Clinical Investigation. 94: 907. PMID 8040346  0.578
1994 Jin YM, Pardoe IU, Burness AT, Michalak TI. Identification and characterization of the cell surface 70-kilodalton sialoglycoprotein(s) as a candidate receptor for encephalomyocarditis virus on human nucleated cells. Journal of Virology. 68: 7308-19. PMID 7933115 DOI: 10.1128/JVI.68.11.7308-7319.1994  0.322
1994 Michalak TI, Lin B. Molecular species of hepadnavirus core and envelope polypeptides in hepatocyte plasma membrane of woodchucks with acute and chronic viral hepatitis Hepatology. 20: 275-286. DOI: 10.1002/HEP.1840200202  0.402
1989 Michalak TI, Snyder RL, Churchill ND. Characterization of the incorporation of woodchuck hepatitis virus surface antigen into hepatocyte plasma membrane in woodchuck hepatitis and in the virus-induced hepatocellular carcinoma. Hepatology (Baltimore, Md.). 10: 44-55. PMID 2535620 DOI: 10.1002/HEP.1840100111  0.426
1988 Michalak TI, Churchill ND. Interaction of woodchuck hepatitis virus surface antigen with hepatocyte plasma membrane in woodchuck chronic hepatitis. Hepatology (Baltimore, Md.). 8: 499-506. PMID 3286458 DOI: 10.1002/HEP.1840080312  0.356
1980 Michalak T, Krawczyński K, Ostrowski J, Nowosławski A. Hepatitis B surface antigen and albumin in human hepatocytes Gastroenterology. 79: 1151-1158. DOI: 10.1016/0016-5085(80)90907-5  0.41
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