Year |
Citation |
Score |
2019 |
Ruch RJ. Connexin43 Suppresses Lung Cancer Stem Cells. Cancers. 11. PMID 30717421 DOI: 10.3390/cancers11020175 |
0.522 |
|
2018 |
Arora S, Heyza JR, Chalfin EC, Ruch RJ, Patrick SM. Gap Junction Intercellular Communication Positively Regulates Cisplatin Toxicity by Inducing DNA Damage through Bystander Signaling. Cancers. 10. PMID 30279363 DOI: 10.3390/Cancers10100368 |
0.316 |
|
2014 |
Ruch RJ, Boucher PD, Gentry BG, Shewach DS. Gap Junctional Intercellular Communication Increases Cytotoxicity and Reduces Resistance to Hydroxyurea Journal of Cancer Therapy. 5: 1190-1202. DOI: 10.4236/Jct.2014.513121 |
0.409 |
|
2012 |
Matesic DF, Sidorova TS, Burns TJ, Bell AM, Tran PL, Ruch RJ, May SW. p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid. Journal of Cellular Biochemistry. 113: 269-81. PMID 21898549 DOI: 10.1002/Jcb.23353 |
0.46 |
|
2005 |
Gentry BG, Im M, Boucher PD, Ruch RJ, Shewach DS. GCV phosphates are transferred between HeLa cells despite lack of bystander cytotoxicity Gene Therapy. 12: 1033-1041. PMID 15789060 DOI: 10.1038/Sj.Gt.3302487 |
0.448 |
|
2003 |
Peebles KA, Duncan MW, Ruch RJ, Malkinson AM. Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1. Carcinogenesis. 24: 651-7. PMID 12727792 DOI: 10.1093/Carcin/Bgg008 |
0.429 |
|
2003 |
Trosko JE, Ruch RJ. Gap junctions as targets for cancer chemoprevention and chemotherapy. Current Drug Targets. 3: 465-82. PMID 12448698 DOI: 10.2174/1389450023347371 |
0.369 |
|
2002 |
Koffler LD, Fernstrom MJ, Akiyama TE, Gonzalez FJ, Ruch RJ. Positive regulation of connexin32 transcription by hepatocyte nuclear factor-1alpha. Archives of Biochemistry and Biophysics. 407: 160-7. PMID 12413486 DOI: 10.1016/S0003-9861(02)00488-5 |
0.631 |
|
2002 |
Fernstrom MJ, Koffler LD, Abou-Rjaily G, Boucher PD, Shewach DS, Ruch RJ. Neoplastic reversal of human ovarian carcinoma cells transfected with connexin43. Experimental and Molecular Pathology. 73: 54-60. PMID 12127054 DOI: 10.1006/Exmp.2002.2436 |
0.661 |
|
2001 |
Ruch RJ, Porter S, Koffler LD, Dwyer-Nield LD, Malkinson AM. Defective gap junctional intercellular communication in lung cancer: loss of an important mediator of tissue homeostasis and phenotypic regulation. Experimental Lung Research. 27: 231-43. PMID 11293326 DOI: 10.1080/019021401300053984 |
0.645 |
|
2000 |
Koffler L, Roshong S, Kyu Park I, Cesen-Cummings K, Thompson DC, Dwyer-Nield LD, Rice P, Mamay C, Malkinson AM, Ruch RJ. Growth inhibition in G(1) and altered expression of cyclin D1 and p27(kip-1 )after forced connexin expression in lung and liver carcinoma cells. Journal of Cellular Biochemistry. 79: 347-54. PMID 10972973 DOI: 10.1002/1097-4644(20001201)79:3<347::Aid-Jcb10>3.0.Co;2-2 |
0.666 |
|
2000 |
Umhauer S, Ruch RJ, Fanning J. Gap junctional intercellular communication and connexin 43 expression in ovarian carcinoma. American Journal of Obstetrics and Gynecology. 182: 999-1000. PMID 10819807 DOI: 10.1016/S0002-9378(00)70135-9 |
0.517 |
|
2000 |
Piechocki MP, Toti RM, Fernstrom MJ, Burk RD, Ruch RJ. Liver cell-specific transcriptional regulation of connexin32. Biochimica Et Biophysica Acta. 1491: 107-22. PMID 10760574 DOI: 10.1016/S0167-4781(00)00036-1 |
0.49 |
|
1999 |
Hanna EA, Umhauer S, Roshong SL, Piechocki MP, Fernstrom MJ, Fanning JD, Ruch RJ. Gap junctional intercellular communication and connexin43 expression in human ovarian surface epithelial cells and ovarian carcinomas in vivo and in vitro. Carcinogenesis. 20: 1369-73. PMID 10383914 DOI: 10.1093/carcin/20.7.1369 |
0.564 |
|
1999 |
Piechocki MP, Burk RD, Ruch RJ. Regulation of connexin32 and connexin43 gene expression by DNA methylation in rat liver cells Carcinogenesis. 20: 401-406. PMID 10190553 DOI: 10.1093/CARCIN/20.3.401 |
0.503 |
|
1998 |
Hayashi T, Nomata K, Chang CC, Ruch RJ, Trosko JE. Cooperative effects of v-myc and c-Ha-ras oncogenes on gap junctional intercellular communication and tumorigenicity in rat liver epithelial cells. Cancer Letters. 128: 145-54. PMID 9683275 DOI: 10.1016/S0304-3835(98)00060-3 |
0.306 |
|
1998 |
Ruch RJ, Cesen-Cummings K, Malkinson AM. Role of gap junctions in lung neoplasia. Experimental Lung Research. 24: 523-39. PMID 9659581 DOI: 10.3109/01902149809087384 |
0.562 |
|
1998 |
Rae RS, Mehta PP, Chang CC, Trosko JE, Ruch RJ. Neoplastic phenotype of gap-junctional intercellular communication- deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32 Molecular Carcinogenesis. 22: 120-127. PMID 9655256 DOI: 10.1002/(Sici)1098-2744(199806)22:2<120::Aid-Mc7>3.0.Co;2-Q |
0.487 |
|
1998 |
Boucher PD, Ruch RJ, Shewach DS. Differential ganciclovir-mediated cytotoxicity and bystander killing in human colon carcinoma cell lines expressing herpes simplex virus thymidine kinase. Human Gene Therapy. 9: 801-14. PMID 9581903 DOI: 10.1089/Hum.1998.9.6-801 |
0.338 |
|
1998 |
Ren P, Mehta PP, Ruch RJ. Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin32-expressing liver cells: Cell specificity and role of protein kinase C Carcinogenesis. 19: 169-175. PMID 9472709 DOI: 10.1093/carcin/19.1.169 |
0.456 |
|
1998 |
Cesen-Cummings K, Fernstrom MJ, Malkinson AM, Ruch RJ. Frequent reduction of gap junctional intercellular communication and connexin43 expression in human and mouse lung carcinoma cells. Carcinogenesis. 19: 61-7. PMID 9472694 DOI: 10.1093/Carcin/19.1.61 |
0.603 |
|
1998 |
Trosko JE, Ruch RJ. Cell-cell communication in carcinogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 3: d208-36. PMID 9458335 DOI: 10.2741/A275 |
0.41 |
|
1997 |
Garber SA, Fernstrom MJ, Stoner GD, Ruch RJ. Altered gap junctional intercellular communication in neoplastic rat esophageal epithelial cells. Carcinogenesis. 18: 1149-53. PMID 9214596 DOI: 10.1093/carcin/18.6.1149 |
0.526 |
|
1996 |
Banoub RW, Fernstrom M, Ruch RJ. Lack of growth inhibition or enhancement of gap junctional intercellular communication and connexin43 expression by beta-carotene in murine lung epithelial cells in vitro. Cancer Letters. 108: 35-40. PMID 8950206 DOI: 10.1016/S0304-3835(96)04367-4 |
0.388 |
|
1996 |
Ren P, Ruch RJ. Inhibition of gap junctional intercellular communication by barbiturates in long-term primary cultured rat hepatocytes is correlated with liver tumour promoting activity Carcinogenesis. 17: 2119-2124. PMID 8895477 DOI: 10.1093/carcin/17.10.2119 |
0.404 |
|
1996 |
de Feijter AW, Matesic DF, Ruch RJ, Guan X, Chang CC, Trosko JE. Localization and function of the connexin 43 gap-junction protein in normal and various oncogene-expressing rat liver epithelial cells. Molecular Carcinogenesis. 16: 203-12. PMID 8784463 DOI: 10.1002/(Sici)1098-2744(199608)16:4<203::Aid-Mc4>3.0.Co;2-G |
0.436 |
|
1996 |
Ruch RJ, Guan X, Sigler K. Inhibition of gap junctional intercellular communication and enhancement of growth in BALB/c 3T3 cells treated with connexin43 antisense oligonucleotides. Molecular Carcinogenesis. 14: 269-74. PMID 8519416 DOI: 10.1002/mc.2940140407 |
0.379 |
|
1995 |
Esinduy CB, Chang CC, Trosko JE, Ruch RJ. In vitro growth inhibition of neoplastically transformed cells by non-transformed cells: requirement for gap junctional intercellular communication. Carcinogenesis. 16: 915-21. PMID 7728974 DOI: 10.1093/Carcin/16.4.915 |
0.388 |
|
1995 |
Guan X, Hardenbrook J, Fernstrom MJ, Chaudhuri R, Malkinson AM, Ruch RJ. Down-regulation by butylated hydroxytoluene of the number and function of gap junctions in epithelial cell lines derived from mouse lung and rat liver. Carcinogenesis. 16: 2575-82. PMID 7586169 DOI: 10.1093/Carcin/16.10.2575 |
0.462 |
|
1995 |
Guan X, Bonney WJ, Ruch RJ. Changes in gap junction permeability, gap junction number, and connexin43 expression in Lindane-treated rat liver epithelial cells Toxicology and Applied Pharmacology. 130: 79-86. PMID 7530866 DOI: 10.1006/taap.1995.1011 |
0.378 |
|
1994 |
Ruch RJ, Bonney WJ, Sigler K, Guan X, Matesic D, Schafer LD, Dupont E, Trosko JE. Loss of gap junctions from ddt-treated rat liver epithelial cells Carcinogenesis. 15: 301-306. PMID 8313522 DOI: 10.1093/Carcin/15.2.301 |
0.468 |
|
1994 |
Ren P, de Feijter AW, Paul DL, Ruch RJ. Enhancement of liver cell gap junction protein expression by glucocorticoids. Carcinogenesis. 15: 1807-13. PMID 7522979 DOI: 10.1093/Carcin/15.9.1807 |
0.556 |
|
1993 |
Sigler K, Ruch RJ. Enhancement of gap junctional intercellular communication in tumor promoter-treated cells by components of green tea. Cancer Letters. 69: 15-9. PMID 8481889 DOI: 10.1016/0304-3835(93)90026-6 |
0.353 |
|
1993 |
Chaudhuri R, Sigler K, Dupont E, Trosko JE, Malkinson AM, Ruch RJ. Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters. Cancer Letters. 71: 11-8. PMID 8395972 DOI: 10.1016/0304-3835(93)90090-V |
0.448 |
|
1987 |
Ruch RJ, Klaunig JE, Pereira MA. Inhibition of intercellular communication between mouse hepatocytes by tumor promoters Toxicology and Applied Pharmacology. 87: 111-120. PMID 2432692 DOI: 10.1016/0041-008X(87)90089-5 |
0.316 |
|
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