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Michael D. Onken, Ph.D. - Publications

Affiliations: 
2000 Washington University, Saint Louis, St. Louis, MO 
Area:
Cell Biology, Molecular Biology, Human Development
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Truong A, Yoo JH, Scherzer M, Sanchez JMS, Dale KJ, Kinsey CG, Richards JR, Shin D, Ghazi P, Onken MD, Blumer KJ, Odelberg SJ, McMahon M. Chloroquine sensitizes GNAQ/11-mutated melanoma to MEK1/2 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32933997 DOI: 10.1158/1078-0432.Ccr-20-1675  0.337
2019 Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ. Abstract 1764: Targeting nucleotide exchange to inhibit Gq/11 driver mutations in uveal melanoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1764  0.305
2018 Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ. Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells. Science Signaling. 11. PMID 30181242 DOI: 10.1126/Scisignal.Aao6852  0.326
2018 Onken MD, Makepeace CM, Wang S, Kaltenbronn KM, Kanai SM, Broekelmann TJ, Cooper JA, Blumer KJ. Abstract 4363: Pharmacologic targeting of Gq reveals new pathways in uveal melanoma Cancer Research. 78: 4363-4363. DOI: 10.1158/1538-7445.Am2018-4363  0.365
2017 Onken MD, Makepeace CM, Wang S, Kaltenbronn KM, Kanai SM, Broekelmann TJ, Cooper JA, Blumer KJ. Abstract 1350: Direct pharmacological targeting of Gq/11 in uveal melanoma Cancer Research. 77: 1350-1350. DOI: 10.1158/1538-7445.Am2017-1350  0.431
2016 Vermeer DW, Coppock JD, Zeng E, Lee KM, Spanos WC, Onken MD, Uppaluri R, Lee JH, Vermeer PD. Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis. Oncotarget. PMID 27013584 DOI: 10.18632/Oncotarget.8254  0.3
2015 Chalivendra V, Kanchi KL, Onken MD, Winkler AE, Mardis E, Uppaluri R. Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer. Genomics Data. 3: 61-62. PMID 25729643 DOI: 10.1016/J.Gdata.2014.11.006  0.344
2014 Onken MD, Li J, Cooper JA. Uveal melanoma cells utilize a novel route for transendothelial migration. Plos One. 9: e115472. PMID 25506912 DOI: 10.1371/Journal.Pone.0115472  0.36
2014 Onken MD, Winkler AE, Kanchi KL, Chalivendra V, Law JH, Rickert CG, Kallogjeri D, Judd NP, Dunn GP, Piccirillo JF, Lewis JS, Mardis ER, Uppaluri R. A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2873-84. PMID 24668645 DOI: 10.1158/1078-0432.Ccr-14-0205  0.315
2014 Onken MD, Mooren OL, Li J, Cooper JA. Abstract 3163: Transendothelial migration of uveal melanoma cells Cancer Research. 74: 3163-3163. DOI: 10.1158/1538-7445.Am2014-3163  0.394
2013 Matatall KA, Agapova OA, Onken MD, Worley LA, Bowcock AM, Harbour JW. BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma. Bmc Cancer. 13: 371. PMID 23915344 DOI: 10.1186/1471-2407-13-371  0.463
2013 Harbour JW, Roberson ED, Anbunathan H, Onken MD, Worley LA, Bowcock AM. Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma. Nature Genetics. 45: 133-5. PMID 23313955 DOI: 10.1038/Ng.2523  0.367
2013 Harbour JW, Wilson D, Finger PT, Worley LA, Onken MD. Gene expressing profiling of iris melanomas. Ophthalmology. 120: 213, 213.e1-3. PMID 23283188 DOI: 10.1016/J.Ophtha.2012.08.016  0.409
2012 Onken MD, Worley LA, Char DH, Augsburger JJ, Correa ZM, Nudleman E, Aaberg TM, Altaweel MM, Bardenstein DS, Finger PT, Gallie BL, Harocopos GJ, Hovland PG, McGowan HD, Milman T, et al. Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma. Ophthalmology. 119: 1596-603. PMID 22521086 DOI: 10.1016/J.Ophtha.2012.02.017  0.362
2012 Landreville S, Agapova OA, Matatall KA, Kneass ZT, Onken MD, Lee RS, Bowcock AM, Harbour JW. Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 408-16. PMID 22038994 DOI: 10.1158/1078-0432.Ccr-11-0946  0.405
2010 Harbour JW, Onken MD, Roberson ED, Duan S, Cao L, Worley LA, Council ML, Matatall KA, Helms C, Bowcock AM. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science (New York, N.Y.). 330: 1410-3. PMID 21051595 DOI: 10.1126/Science.1194472  0.394
2010 Onken MD, Worley LA, Harbour JW. Association between gene expression profile, proliferation and metastasis in uveal melanoma. Current Eye Research. 35: 857-63. PMID 20795869 DOI: 10.3109/02713683.2010.493265  0.38
2010 Onken MD, Worley LA, Tuscan MD, Harbour JW. An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma. The Journal of Molecular Diagnostics : Jmd. 12: 461-8. PMID 20413675 DOI: 10.2353/Jmoldx.2010.090220  0.398
2008 Onken MD, Worley LA, Long MD, Duan S, Council ML, Bowcock AM, Harbour JW. Oncogenic mutations in GNAQ occur early in uveal melanoma. Investigative Ophthalmology & Visual Science. 49: 5230-4. PMID 18719078 DOI: 10.1167/Iovs.08-2145  0.303
2008 Onken MD, Worley LA, Harbour JW. A metastasis modifier locus on human chromosome 8p in uveal melanoma identified by integrative genomic analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3737-45. PMID 18559591 DOI: 10.1158/1078-0432.Ccr-07-5144  0.409
2008 Chang SH, Worley LA, Onken MD, Harbour JW. Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis. Melanoma Research. 18: 191-200. PMID 18477893 DOI: 10.1097/Cmr.0B013E3283005270  0.439
2008 Worley LA, Long MD, Onken MD, Harbour JW. Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling. Melanoma Research. 18: 184-90. PMID 18477892 DOI: 10.1097/Cmr.0B013E3282Feeac6  0.309
2008 Ehlers JP, Worley L, Onken MD, Harbour JW. Integrative genomic analysis of aneuploidy in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 115-22. PMID 18172260 DOI: 10.1158/1078-0432.Ccr-07-1825  0.365
2007 Worley LA, Onken MD, Person E, Robirds D, Branson J, Char DH, Perry A, Harbour JW. Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1466-71. PMID 17332290 DOI: 10.1158/1078-0432.Ccr-06-2401  0.349
2006 Onken MD, Worley LA, Dávila RM, Char DH, Harbour JW. Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens. The Journal of Molecular Diagnostics : Jmd. 8: 567-73. PMID 17065425 DOI: 10.2353/Jmoldx.2006.060077  0.357
2006 Onken MD, Ehlers JP, Worley LA, Makita J, Yokota Y, Harbour JW. Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas. Cancer Research. 66: 4602-9. PMID 16651410 DOI: 10.1158/0008-5472.Can-05-4196  0.418
2005 Onken MD, Lin AY, Worley LA, Folberg R, Harbour JW. Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas. American Journal of Ophthalmology. 140: 748-9. PMID 16226537 DOI: 10.1016/J.Ajo.2005.04.024  0.337
2005 Ehlers JP, Worley L, Onken MD, Harbour JW. DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 3609-13. PMID 15897555 DOI: 10.1158/1078-0432.Ccr-04-1941  0.326
2004 Onken MD, Worley LA, Ehlers JP, Harbour JW. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Research. 64: 7205-9. PMID 15492234 DOI: 10.1158/0008-5472.Can-04-1750  0.389
1994 Sheppard AM, Onken MD, Rosen GD, Noakes PG, Dean DC. Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhesion and Communication. 2: 27-43. PMID 7526952 DOI: 10.3109/15419069409014200  0.484
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