| Year |
Citation |
Score |
| 2020 |
Singh KS, Leu JI, Barnoud T, Vonteddu P, Gnanapradeepan K, Lin C, Liu Q, Barton JC, Kossenkov AV, George DL, Murphy ME, Dotiwala F. African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin. Nature Communications. 11: 473. PMID 31980600 DOI: 10.1038/S41467-019-14151-9 |
0.302 |
|
| 2019 |
Leu JI, Murphy ME, George DL. Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53. Proceedings of the National Academy of Sciences of the United States of America. PMID 30962386 DOI: 10.1073/Pnas.1821277116 |
0.357 |
|
| 2017 |
Leu JI, Barnoud T, Zhang G, Tian T, Wei Z, Herlyn M, Murphy ME, George DL. Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function. Oncotarget. PMID 28484090 DOI: 10.18632/Oncotarget.17321 |
0.313 |
|
| 2016 |
Jennis M, Kung CP, Basu S, Budina-Kolomets A, Leu JI, Khaku S, Scott JP, Cai KQ, Campbell MR, Porter DK, Wang X, Bell DA, Li X, Garlick DS, Liu Q, et al. An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model. Genes & Development. PMID 27034505 DOI: 10.1101/Gad.275891.115 |
0.338 |
|
| 2014 |
Leu JI, Zhang P, Murphy ME, Marmorstein R, George DL. Structural basis for the inhibition of HSP70 and DnaK chaperones by small-molecule targeting of a C-terminal allosteric pocket. Acs Chemical Biology. 9: 2508-16. PMID 25148104 DOI: 10.1021/Cb500236Y |
0.339 |
|
| 2013 |
Leu JI, Murphy ME, George DL. The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver. Journal of Liver. 2. PMID 23991369 DOI: 10.4172/2167-0889.1000117 |
0.384 |
|
| 2012 |
Balaburski G, Leu JI, Andrake M, Hayik S, Beeharry N, Dunbrack R, Yen T, George DL, Murphy ME. Abstract 3793: Characterization of the mechanism of action of a novel small molecule inhibitor of HSP70 Cancer Research. 72: 3793-3793. DOI: 10.1158/1538-7445.Am2012-3793 |
0.352 |
|
| 2011 |
Leu JI, Pimkina J, Pandey P, Murphy ME, George DL. HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. Molecular Cancer Research : McR. 9: 936-47. PMID 21636681 DOI: 10.1158/1541-7786.Mcr-11-0019 |
0.335 |
|
| 2011 |
Frank AK, Leu JI, Zhou Y, Devarajan K, Nedelko T, Klein-Szanto A, Hollstein M, Murphy ME. The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation. Molecular and Cellular Biology. 31: 1201-13. PMID 21245379 DOI: 10.1128/Mcb.01136-10 |
0.353 |
|
| 2007 |
Leu JI, George DL. Hepatic IGFBP1 is a prosurvival factor that binds to BAK, protects the liver from apoptosis, and antagonizes the proapoptotic actions of p53 at mitochondria. Genes & Development. 21: 3095-109. PMID 18056423 DOI: 10.1101/gad.1567107 |
0.378 |
|
| 2003 |
Leu JI, Crissey MA, Craig LE, Taub R. Impaired hepatocyte DNA synthetic response posthepatectomy in insulin-like growth factor binding protein 1-deficient mice with defects in C/EBP beta and mitogen-activated protein kinase/extracellular signal-regulated kinase regulation. Molecular and Cellular Biology. 23: 1251-9. PMID 12556485 DOI: 10.1128/Mcb.23.4.1251-1259.2003 |
0.659 |
|
| 2003 |
Leu JI, Crissey MA, Taub R. Massive hepatic apoptosis associated with TGF-beta1 activation after Fas ligand treatment of IGF binding protein-1-deficient mice. The Journal of Clinical Investigation. 111: 129-39. PMID 12511596 DOI: 10.1172/Jci16712 |
0.642 |
|
| 2002 |
Macias-Silva M, Li W, Leu JI, Crissey MA, Taub R. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration. The Journal of Biological Chemistry. 277: 28483-90. PMID 12023281 DOI: 10.1074/Jbc.M202403200 |
0.614 |
|
| 2001 |
Li W, Liang X, Leu JI, Kovalovich K, Ciliberto G, Taub R. Global changes in interleukin-6-dependent gene expression patterns in mouse livers after partial hepatectomy. Hepatology (Baltimore, Md.). 33: 1377-86. PMID 11391526 DOI: 10.1053/Jhep.2001.24431 |
0.603 |
|
| 2001 |
Leu JI, Crissey MA, Leu JP, Ciliberto G, Taub R. Interleukin-6-induced STAT3 and AP-1 amplify hepatocyte nuclear factor 1-mediated transactivation of hepatic genes, an adaptive response to liver injury. Molecular and Cellular Biology. 21: 414-24. PMID 11134330 DOI: 10.1128/Mcb.21.2.414-424.2001 |
0.646 |
|
| 1999 |
Crissey MA, Leu JI, DeAngelis RA, Greenbaum LE, Scearce LM, Kovalovich K, Taub R. Liver-specific and proliferation-induced deoxyribonuclease I hypersensitive sites in the mouse insulin-like growth factor binding protein-1 gene. Hepatology (Baltimore, Md.). 30: 1187-97. PMID 10534340 DOI: 10.1002/Hep.510300520 |
0.627 |
|
| 1998 |
Du K, Leu JI, Peng Y, Taub R. Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. The Journal of Biological Chemistry. 273: 35208-15. PMID 9857059 DOI: 10.1074/Jbc.273.52.35208 |
0.639 |
|
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