Eileen M. Shore - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Towler OW, Kaplan FS, Shore EM. The Developmental Phenotype of the Great Toe in Fibrodysplasia Ossificans Progressiva. Frontiers in Cell and Developmental Biology. 8: 612853. PMID 33364240 DOI: 10.3389/fcell.2020.612853  0.36
2020 Towler OW, Peck SH, Kaplan FS, Shore EM. Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP). Developmental Biology. PMID 33217406 DOI: 10.1016/j.ydbio.2020.11.004  0.36
2020 Kaplan FS, Al Mukaddam M, Stanley A, Towler OW, Shore EM. Fibrodysplasia Ossificans Progressiva (FOP): A Disorder of Osteochondrogenesis. Bone. 115539. PMID 32730934 DOI: 10.1016/j.bone.2020.115539  0.36
2019 Towler OW, Shore EM, Kaplan FS. Skeletal malformations and developmental arthropathy in individuals who have fibrodysplasia ossificans progressiva. Bone. 115116. PMID 31655222 DOI: 10.1016/j.bone.2019.115116  0.36
2019 Gucev Z, Tasic V, Plaseska-Karanfilska D, Dimishkovska M, Laban N, Bozinovski Z, Kostovski M, Saveski A, Polenakovic M, Towler OW, Shore EM, Kaplan FS. Severe digital malformations in a rare variant of fibrodysplasia ossificans progressiva. American Journal of Medical Genetics. Part A. PMID 31012264 DOI: 10.1002/ajmg.a.61153  0.36
2018 Kaplan FS, Pignolo RJ, Shore EM. Heterotopic Ossification: The Keys to the Kingdom. Bone. 109: 1-2. PMID 29567209 DOI: 10.1016/j.bone.2018.03.001  0.36
2018 Amalfitano M, Fyfe B, Thomas SV, Egan KP, Xu M, Smith AG, Kaplan FS, Shore EM, Pignolo RJ. A case report of mesenteric heterotopic ossification: Histopathologic and genetic findings. Bone. PMID 29320714 DOI: 10.1016/j.bone.2018.01.006  0.36
2017 Convente MR, Chakkalakal SA, Yang E, Caron RJ, Zhang D, Kambayashi T, Kaplan FS, Shore EM. Reply to: Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29194751 DOI: 10.1002/jbmr.3349  0.36
2017 Ramaswamy G, Fong J, Brewer N, Kim H, Zhang D, Choi Y, Kaplan FS, Shore EM. Ablation of Gsα signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance. Bone. PMID 29183785 DOI: 10.1016/j.bone.2017.11.019  0.36
2017 Kaplan FS, Pignolo RJ, Al Mukaddam MM, Shore EM. Hard targets for a second skeleton: therapeutic horizons for fibrodysplasia ossificans progressiva (FOP). Expert Opinion On Orphan Drugs. 5: 291-294. PMID 29177121 DOI: 10.1080/21678707.2017.1304211  0.36
2017 Wang H, Shore EM, Pignolo RJ, Kaplan FS. Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP). Bone. PMID 29170109 DOI: 10.1016/j.bone.2017.11.014  0.36
2017 Convente MR, Chakkalakal SA, Yang E, Caron RJ, Zhang D, Kambayashi T, Kaplan FS, Shore EM. Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1(R206H) Mouse Model of Fibrodysplasia Ossificans Progressiva. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28986986 DOI: 10.1002/jbmr.3304  0.36
2017 Towler OW, Shore EM, Xu M, Bamford A, Anderson I, Pignolo RJ, Kaplan FS. The congenital great toe malformation of fibrodysplasia ossificans progressiva? - A close call. European Journal of Medical Genetics. PMID 28473268 DOI: 10.1016/j.ejmg.2017.04.013  0.36
2017 Ramaswamy G, Kim H, Zhang D, Lounev V, Wu JY, Choi Y, Kaplan FS, Pignolo RJ, Shore EM. Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways. Scientific Reports. 7: 45140. PMID 28338087 DOI: 10.1038/srep45140  0.36
2016 Rajapakse CS, Lindborg C, Wang H, Newman BT, Kobe EA, Chang G, Shore EM, Kaplan FS, Pignolo RJ. Analog Method for Radiographic Assessment of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva. Academic Radiology. PMID 27989444 DOI: 10.1016/j.acra.2016.10.010  0.36
2016 Pang J, Zuo Y, Chen Y, Song L, Zhu Q, Yu J, Shan C, Cai Z, Hao J, Kaplan FS, Shore EM, Zhang K. ACVR1-Fc Suppresses BMP Signaling and Chondro-osseous Differentiation in an in vitro Model of Fibrodysplasia Ossificans Progressiva. Bone. PMID 27492611 DOI: 10.1016/j.bone.2016.07.023  0.36
2016 Wang H, Lindborg C, Lounev V, Kim JH, McCarrick-Walmsley R, Xu M, Mangiavini L, Groppe JC, Shore EM, Schipani E, Kaplan FS, Pignolo RJ. Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27027798 DOI: 10.1002/jbmr.2848  0.36
2016 Pignolo RJ, Bedford-Gay C, Liljesthröm M, Durbin-Johnson BP, Shore EM, Rocke DM, Kaplan FS. The Natural History of Flare-Ups in Fibrodysplasia Ossificans Progressiva (FOP): A Comprehensive Global Assessment. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 31: 650-6. PMID 27025942 DOI: 10.1002/jbmr.2728  0.36
2016 Chakkalakal SA, Uchibe K, Convente MR, Zhang D, Economides AN, Kaplan FS, Pacifici M, Iwamoto M, Shore EM. Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice with the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26896819 DOI: 10.1002/jbmr.2820  0.36
2016 Pacifici M, Shore EM. Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders. Cytokine & Growth Factor Reviews. 27: 93-104. PMID 26776312 DOI: 10.1016/j.cytogfr.2015.12.007  0.36
2016 Kaplan FS, Pignolo RJ, Shore EM. Granting immunity to FOP and catching heterotopic ossification in the Act. Seminars in Cell & Developmental Biology. 49: 30-6. PMID 26706149 DOI: 10.1016/j.semcdb.2015.12.013  0.36
2016 Kaplan FS, Pignolo RJ, Shore EM. Granting immunity to FOP and catching heterotopic ossification in the Act Seminars in Cell and Developmental Biology. 49: 30-36. DOI: 10.1016/j.semcdb.2015.12.013  0.36
2015 Peck SH, O'Donnell PJ, Kang JL, Malhotra NR, Dodge GR, Pacifici M, Shore EM, Haskins ME, Smith LJ. Delayed hypertrophic differentiation of epiphyseal chondrocytes contributes to failed secondary ossification in mucopolysaccharidosis VII dogs. Molecular Genetics and Metabolism. PMID 26422116 DOI: 10.1016/j.ymgme.2015.09.008  0.36
2015 Kaplan FS, Kobori JA, Orellana C, Calvo I, Rosello M, Martinez F, Lopez B, Xu M, Pignolo RJ, Shore EM, Groppe JC. Multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva (ACVR1 c.772G>A; R258G): A report of two patients. American Journal of Medical Genetics. Part A. PMID 26097044 DOI: 10.1002/ajmg.a.37205  0.36
2015 Convente MR, Wang H, Pignolo RJ, Kaplan FS, Shore EM. The immunological contribution to heterotopic ossification disorders. Current Osteoporosis Reports. 13: 116-24. PMID 25687936 DOI: 10.1007/s11914-015-0258-z  0.36
2015 Pignolo RJ, Ramaswamy G, Fong JT, Shore EM, Kaplan FS. Progressive osseous heteroplasia: diagnosis, treatment, and prognosis. The Application of Clinical Genetics. 8: 37-48. PMID 25674011 DOI: 10.2147/TACG.S51064  0.36
2015 Bravenboer N, Micha D, Triffit JT, Bullock AN, Ravazollo R, Bocciardi R, di Rocco M, Netelenbos JC, Ten Dijke P, Sánchez-Duffhues G, Kaplan FS, Shore EM, Pignolo RJ, Seemann P, Ventura F, et al. Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva. European Journal of Human Genetics : Ejhg. 23. PMID 25604857 DOI: 10.1038/ejhg.2014.274  0.36
2015 Bravenboer N, Micha D, Triffit JT, Bullock AN, Ravazollo R, Bocciardi R, di Rocco M, Netelenbos JC, Ten Dijke P, Sánchez-Duffhues G, Kaplan FS, Shore EM, Pignolo RJ, Seemann P, Ventura F, et al. Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva European Journal of Human Genetics. DOI: 10.1038/ejhg.2014.274  0.36
2015 Convente MR, Wang H, Pignolo RJ, Kaplan FS, Shore EM. The Immunological Contribution to Heterotopic Ossification Disorders Current Osteoporosis Reports. 13: 116-124. DOI: 10.1007/s11914-015-0258-z  0.36
2014 Chiaro JA, O'Donnell P, Shore EM, Malhotra NR, Ponder KP, Haskins ME, Smith LJ. Effects of neonatal enzyme replacement therapy and simvastatin treatment on cervical spine disease in mucopolysaccharidosis I dogs. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 2610-7. PMID 24898323 DOI: 10.1002/jbmr.2290  0.36
2014 Haupt J, Deichsel A, Stange K, Ast C, Bocciardi R, Ravazzolo R, Di Rocco M, Ferrari P, Landi A, Kaplan FS, Shore EM, Reissner C, Seemann P. ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant Human Molecular Genetics. 23: 5364-5377. PMID 24852373 DOI: 10.1093/hmg/ddu255  0.36
2014 Culbert AL, Chakkalakal SA, Theosmy EG, Brennan TA, Kaplan FS, Shore EM. Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification Stem Cells. 32: 1289-1300. PMID 24449086 DOI: 10.1002/stem.1633  0.36
2013 Kaplan FS, Pignolo RJ, Shore EM. From mysteries to medicines: drug development for fibrodysplasia ossificans progressive. Expert Opinion On Orphan Drugs. 1: 637-649. PMID 24800180 DOI: 10.1517/21678707.2013.825208  0.36
2013 Regard JB, Malhotra D, Gvozdenovic-Jeremic J, Josey M, Chen M, Weinstein LS, Lu J, Shore EM, Kaplan FS, Yang Y. Activation of hedgehog signaling by loss of GNAS causes heterotopic ossification Nature Medicine. 19: 1505-1512. PMID 24076664 DOI: 10.1038/nm.3314  0.36
2013 Zhang W, Zhang K, Song L, Pang J, Ma H, Shore EM, Kaplan FS, Wang P. The phenotype and genotype of fibrodysplasia ossificans progressiva in China: A report of 72 cases Bone. 57: 386-391. PMID 24051199 DOI: 10.1016/j.bone.2013.09.002  0.36
2013 Cairns DM, Pignolo RJ, Uchimura T, Brennan TA, Lindborg CM, Xu M, Kaplan FS, Shore EM, Zeng L. Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia Journal of Clinical Investigation. 123: 3624-3633. PMID 23863715 DOI: 10.1172/JCI69746  0.36
2013 Pignolo RJ, Shore EM, Kaplan FS. Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons. Pediatric Endocrinology Reviews : Per. 10: 437-448. PMID 23858627  0.36
2013 Chiaro JA, Baron MD, Del Alcazar CM, O'Donnell P, Shore EM, Elliott DM, Ponder KP, Haskins ME, Smith LJ. Postnatal progression of bone disease in the cervical spines of mucopolysaccharidosis I dogs. Bone. 55: 78-83. PMID 23563357 DOI: 10.1016/j.bone.2013.03.014  0.36
2013 Kaplan FS, Pignolo RJ, Shore EM. From mysteries to medicines: Drug development for fibrodysplasia ossificans progressiva Expert Opinion On Orphan Drugs. 1: 637-649. DOI: 10.1517/21678707.2013.825208  0.36
2013 Culbert AL, Chakkalakal SA, Convente MR, Lounev VY, Kaplan FS, Shore EM. Fibrodysplasia (Myositis) Ossificans Progressiva Genetics of Bone Biology and Skeletal Disease. 375-393. DOI: 10.1016/B978-0-12-387829-8.00024-X  0.36
2012 Muglu JA, Garg A, Pandiarajan T, Shore EM, Kaplan FS, Uchil D, Dickson MJ. Pregnancy in fibrodysplasia ossificans progressiva. Obstetric Medicine. 5: 35-8. PMID 27579132 DOI: 10.1258/om.2011.110042  0.36
2012 La Sala LF, Pozzi LM, McAloose D, Kaplan FS, Shore EM, Kompanje EJ, Sidor IF, Musmeci L, Uhart MM. Severe soft tissue ossification in a southern right whale Eubalaena australis. Diseases of Aquatic Organisms. 102: 149-56. PMID 23269389 DOI: 10.3354/dao02538  0.36
2012 Kaplan FS, Chakkalakal SA, Shore EM. Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis. Disease Models & Mechanisms. 5: 756-62. PMID 23115204 DOI: 10.1242/dmm.010280  0.36
2012 Zhang S, Kaplan FS, Shore EM. Different roles of GNAS and cAMP signaling during early and late stages of osteogenic differentiation. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 44: 724-31. PMID 22903279 DOI: 10.1055/s-0032-1321845  0.36
2012 Kitterman JA, Strober JB, Kan L, Rocke DM, Cali A, Peeper J, Snow J, Delai PL, Morhart R, Pignolo RJ, Shore EM, Kaplan FS. Neurological symptoms in individuals with fibrodysplasia ossificans progressiva. Journal of Neurology. 259: 2636-43. PMID 22752062 DOI: 10.1007/s00415-012-6562-y  0.36
2012 Kan L, Kitterman JA, Procissi D, Chakkalakal S, Peng CY, McGuire TL, Goldsby RE, Pignolo RJ, Shore EM, Kaplan FS, Kessler JA. CNS demyelination in fibrodysplasia ossificans progressiva. Journal of Neurology. 259: 2644-55. PMID 22736080 DOI: 10.1007/s00415-012-6563-x  0.36
2012 Hammond P, Suttie M, Hennekam RC, Allanson J, Shore EM, Kaplan FS. The face signature of fibrodysplasia ossificans progressiva. American Journal of Medical Genetics. Part A. 158: 1368-80. PMID 22581580 DOI: 10.1002/ajmg.a.35346  0.36
2012 Zimmer J, Doelken SC, Horn D, Groppe JC, Shore EM, Kaplan FS, Seemann P. Functional analysis of alleged NOGGIN mutation G92E disproves its pathogenic relevance. Plos One. 7: e35062. PMID 22529972 DOI: 10.1371/journal.pone.0035062  0.36
2012 Liu JJ, Russell E, Zhang D, Kaplan FS, Pignolo RJ, Shore EM. Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo. Stem Cells (Dayton, Ohio). 30: 1477-85. PMID 22511293 DOI: 10.1002/stem.1109  0.36
2012 Chakkalakal SA, Zhang D, Culbert AL, Convente MR, Caron RJ, Wright AC, Maidment AD, Kaplan FS, Shore EM. An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1746-56. PMID 22508565 DOI: 10.1002/jbmr.1637  0.36
2012 Kaplan J, Kaplan FS, Shore EM. Restoration of normal BMP signaling levels and osteogenic differentiation in FOP mesenchymal progenitor cells by mutant allele-specific targeting. Gene Therapy. 19: 786-90. PMID 22011642 DOI: 10.1038/gt.2011.152  0.36
2012 Shore EM, Kaplan FS. Extraskeletal Bone Formation Pediatric Bone. 821-840. DOI: 10.1016/B978-0-12-382040-2.10030-9  0.36
2012 Hammond P, Suttie M, Hennekam RC, Allanson J, Shore EM, Kaplan FS. The complex craniofacial signature of fibrodysplasia ossificans progressiva: Whose handwriting is it? American Journal of Medical Genetics, Part A. 158: 2979-2980. DOI: 10.1002/ajmg.a.35616  0.36
2011 Pignolo RJ, Shore EM, Kaplan FS. Fibrodysplasia ossificans progressiva: clinical and genetic aspects. Orphanet Journal of Rare Diseases. 6: 80. PMID 22133093 DOI: 10.1186/1750-1172-6-80  0.36
2011 Kaplan FS, Lounev VY, Wang H, Pignolo RJ, Shore EM. Fibrodysplasia ossificans progressiva: a blueprint for metamorphosis. Annals of the New York Academy of Sciences. 1237: 5-10. PMID 22082359 DOI: 10.1111/j.1749-6632.2011.06195.x  0.36
2011 Pignolo RJ, Xu M, Russell E, Richardson A, Kaplan J, Billings PC, Kaplan FS, Shore EM. Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2647-55. PMID 21812029 DOI: 10.1002/jbmr.481  0.36
2011 Kan L, Lounev VY, Pignolo RJ, Duan L, Liu Y, Stock SR, McGuire TL, Lu B, Gerard NP, Shore EM, Kaplan FS, Kessler JA. Substance P signaling mediates BMP-dependent heterotopic ossification. Journal of Cellular Biochemistry. 112: 2759-72. PMID 21748788 DOI: 10.1002/jcb.23259  0.36
2011 Groppe JC, Wu J, Shore EM, Kaplan FS. In vitro analyses of the dysregulated R206H ALK2 kinase-FKBP12 interaction associated with heterotopic ossification in FOP. Cells, Tissues, Organs. 194: 291-5. PMID 21525719 DOI: 10.1159/000324230  0.36
2011 Kaplan FS, Shore EM. Derailing heterotopic ossification and RARing to go. Nature Medicine. 17: 420-1. PMID 21475232 DOI: 10.1038/nm0411-420  0.36
2011 Shore EM, Kaplan FS. Role of altered signal transduction in heterotopic ossification and fibrodysplasia ossificans progressiva. Current Osteoporosis Reports. 9: 83-8. PMID 21340697 DOI: 10.1007/s11914-011-0046-3  0.36
2010 Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Conversion of vascular endothelial cells into multipotent stem-like cells. Nature Medicine. 16: 1400-6. PMID 21102460 DOI: 10.1038/nm.2252  0.36
2010 Kaplan FS, Seemann P, Haupt J, Xu M, Lounev VY, Mullins M, Shore EM. Investigations of activated ACVR1/ALK2, a bone morphogenetic protein type I receptor, that causes fibrodysplasia ossificans progressiva. Methods in Enzymology. 484: 357-73. PMID 21036241 DOI: 10.1016/B978-0-12-381298-8.00018-6  0.36
2010 Kaplan FS, Pignolo RJ, Shore EM. Viewing FOP through rosi-colored glasses. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 2295-6. PMID 20717980 DOI: 10.1002/jbmr.214  0.36
2010 Shore EM, Kaplan FS. Inherited human diseases of heterotopic bone formation. Nature Reviews. Rheumatology. 6: 518-27. PMID 20703219 DOI: 10.1038/nrrheum.2010.122  0.36
2010 Kartal-Kaess M, Shore EM, Xu M, Schwering L, Uhl M, Korinthenberg R, Niemeyer C, Kaplan FS, Lauten M. Fibrodysplasia ossificans progressiva (FOP): watch the great toes! European Journal of Pediatrics. 169: 1417-21. PMID 20577760 DOI: 10.1007/s00431-010-1232-5  0.36
2010 Kaplan FS, Zasloff MA, Kitterman JA, Shore EM, Hong CC, Rocke DM. Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva. The Journal of Bone and Joint Surgery. American Volume. 92: 686-91. PMID 20194327 DOI: 10.2106/JBJS.I.00705  0.36
2010 Schimmel RJ, Pasmans SG, Xu M, Stadhouders-Keet SA, Shore EM, Kaplan FS, Wulffraat NM. GNAS-associated disorders of cutaneous ossification: two different clinical presentations. Bone. 46: 868-72. PMID 19900597 DOI: 10.1016/j.bone.2009.11.001  0.36
2009 Kaplan FS, Pignolo RJ, Shore EM. The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling. Cytokine & Growth Factor Reviews. 20: 399-407. PMID 19896889 DOI: 10.1016/j.cytogfr.2009.10.006  0.36
2009 Shen Q, Little SC, Xu M, Haupt J, Ast C, Katagiri T, Mundlos S, Seemann P, Kaplan FS, Mullins MC, Shore EM. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. The Journal of Clinical Investigation. 119: 3462-72. PMID 19855136 DOI: 10.1172/JCI37412  0.36
2009 Suda RK, Billings PC, Egan KP, Kim JH, McCarrick-Walmsley R, Glaser DL, Porter DL, Shore EM, Pignolo RJ. Circulating osteogenic precursor cells in heterotopic bone formation. Stem Cells (Dayton, Ohio). 27: 2209-19. PMID 19522009 DOI: 10.1002/stem.150  0.36
2009 Moore RE, Dormans JP, Drummond DS, Shore EM, Kaplan FS, Auerbach JD. Chin-on-chest deformity in patients with fibrodysplasia ossificans progressiva: A case series Journal of Bone and Joint Surgery - Series A. 91: 1497-1502. PMID 19487531 DOI: 10.2106/JBJS.H.00554  0.36
2009 Lounev VY, Ramachandran R, Wosczyna MN, Yamamoto M, Maidment AD, Shore EM, Glaser DL, Goldhamer DJ, Kaplan FS. Identification of progenitor cells that contribute to heterotopic skeletogenesis. The Journal of Bone and Joint Surgery. American Volume. 91: 652-63. PMID 19255227 DOI: 10.2106/JBJS.H.01177  0.36
2009 Kaplan FS, Xu M, Seemann P, Connor JM, Glaser DL, Carroll L, Delai P, Fastnacht-Urban E, Forman SJ, Gillessen-Kaesbach G, Hoover-Fong J, Köster B, Pauli RM, Reardon W, Zaidi SA, ... ... Shore EM, et al. Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1. Human Mutation. 30: 379-90. PMID 19085907 DOI: 10.1002/humu.20868  0.36
2009 Huang AH, Motlekar NA, Stein A, Shore EM, Diamond SL, Mauck RL. High-throughput screening of chemical libraries for modulators of mesenchymal stem cell chondrogenesis Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 1055-1056.  0.36
2008 Kaplan FS, Groppe J, Shore EM. When one skeleton is enough: approaches and strategies for the treatment of fibrodysplasia ossificans progressiva (FOP). Drug Discovery Today. Therapeutic Strategies. 5: 255-262. PMID 23599718 DOI: 10.1016/j.ddstr.2008.11.004  0.36
2008 Kaplan FS, Shen Q, Lounev V, Seemann P, Groppe J, Katagiri T, Pignolo RJ, Shore EM. Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP). Journal of Bone and Mineral Metabolism. 26: 521-30. PMID 18979151 DOI: 10.1007/s00774-008-0879-8  0.36
2008 Huang AH, Motlekar NA, Stein A, Diamond SL, Shore EM, Mauck RL. High-throughput screening for modulators of mesenchymal stem cell chondrogenesis. Annals of Biomedical Engineering. 36: 1909-21. PMID 18791827 DOI: 10.1007/s10439-008-9562-4  0.36
2008 Shore EM, Kaplan FS. Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP). Bone. 43: 427-33. PMID 18590993 DOI: 10.1016/j.bone.2008.05.013  0.36
2008 Kaplan FS, Xu M, Glaser DL, Collins F, Connor M, Kitterman J, Sillence D, Zackai E, Ravitsky V, Zasloff M, Ganguly A, Shore EM. Early diagnosis of fibrodysplasia ossificans progressiva. Pediatrics. 121: e1295-300. PMID 18450872 DOI: 10.1542/peds.2007-1980  0.36
2008 Zaghloul KA, Heuer GG, Guttenberg MD, Shore EM, Kaplan FS, Storm PB. Lumbar puncture and surgical intervention in a child with undiagnosed fibrodysplasia ossificans progressiva. Journal of Neurosurgery. Pediatrics. 1: 91-4. PMID 18352811 DOI: 10.3171/PED-08/01/091  0.36
2008 Kaplan FS, Le Merrer M, Glaser DL, Pignolo RJ, Goldsby RE, Kitterman JA, Groppe J, Shore EM. Fibrodysplasia ossificans progressiva. Best Practice & Research. Clinical Rheumatology. 22: 191-205. PMID 18328989 DOI: 10.1016/j.berh.2007.11.007  0.36
2008 Deirmengian GK, Hebela NM, O'Connell M, Glaser DL, Shore EM, Kaplan FS. Proximal tibial osteochondromas in patients with fibrodysplasia ossificans progressiva. The Journal of Bone and Joint Surgery. American Volume. 90: 366-74. PMID 18245597 DOI: 10.2106/JBJS.G.00774  0.36
2008 Billings PC, Fiori JL, Bentwood JL, O'Connell MP, Jiao X, Nussbaum B, Caron RJ, Shore EM, Kaplan FS. Dysregulated BMP signaling and enhanced osteogenic differentiation of connective tissue progenitor cells from patients with fibrodysplasia ossificans progressiva (FOP) Journal of Bone and Mineral Research. 23: 305-313. PMID 17967130 DOI: 10.1359/jbmr.071030  0.36
2007 Kaplan FS, Groppe J, Pignolo RJ, Shore EM. Morphogen receptor genes and metamorphogenes: skeleton keys to metamorphosis. Annals of the New York Academy of Sciences. 1116: 113-33. PMID 17872396 DOI: 10.1196/annals.1402.039  0.36
2007 Groppe JC, Shore EM, Kaplan FS. Functional modeling of the ACVR1 (R206H) mutation in FOP. Clinical Orthopaedics and Related Research. 462: 87-92. PMID 17572636 DOI: 10.1097/BLO.0b013e318126c049  0.36
2007 Yeon HB, Kaplan FS, Shore EM, Rosenberg AE, Jupiter JB. Focal fibronodular heterotopic ossification. A case report. The Journal of Bone and Joint Surgery. American Volume. 89: 1329-36. PMID 17545438 DOI: 10.2106/JBJS.E.01386  0.36
2007 O'Connell MP, Billings PC, Fiori JL, Deirmengian G, Roach HI, Shore EM, Kaplan FS. HSPG modulation of BMP signaling in fibrodysplasia ossificans progressiva cells. Journal of Cellular Biochemistry. 102: 1493-503. PMID 17516498 DOI: 10.1002/jcb.21370  0.36
2007 Kaplan FS, Glaser DL, Pignolo RJ, Shore EM. A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton. Expert Opinion On Biological Therapy. 7: 705-12. PMID 17477807 DOI: 10.1517/14712598.7.5.705  0.36
2007 Feldman GJ, Billings PC, Patel RV, Caron RJ, Guenther C, Kingsley DM, Kaplan FS, Shore EM. Over-expression of BMP4 and BMP5 in a child with axial skeletal malformations and heterotopic ossification: a new syndrome. American Journal of Medical Genetics. Part A. 143: 699-706. PMID 17345627 DOI: 10.1002/ajmg.a.31649  0.36
2007 Gelfand IM, Hub RS, Shore EM, Kaplan FS, Dimeglio LA. Progressive osseous heteroplasia-like heterotopic ossification in a male infant with pseudohypoparathyroidism type Ia: a case report. Bone. 40: 1425-8. PMID 17321228 DOI: 10.1016/j.bone.2006.12.058  0.36
2007 Kaplan FS, Glaser DL, Shore EM, Pignolo RJ, Xu M, Zhang Y, Senitzer D, Forman SJ, Emerson SG. Hematopoietic stem-cell contribution to ectopic skeletogenesis. The Journal of Bone and Joint Surgery. American Volume. 89: 347-57. PMID 17272450 DOI: 10.2106/JBJS.F.00472  0.36
2007 Jiao X, Billings PC, O'Connell MP, Kaplan FS, Shore EM, Glaser DL. Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. The Journal of Biological Chemistry. 282: 1080-6. PMID 17020882 DOI: 10.1074/jbc.M513414200  0.36
2006 Kaplan FS, Fiori J, DE LA Peña LS, Ahn J, Billings PC, Shore EM. Dysregulation of the BMP-4 signaling pathway in fibrodysplasia ossificans progressiva. Annals of the New York Academy of Sciences. 1068: 54-65. PMID 16831905 DOI: 10.1196/annals.1346.008  0.36
2006 Fiori JL, Billings PC, de la Peña LS, Kaplan FS, Shore EM. Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP). Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 902-9. PMID 16753021 DOI: 10.1359/jbmr.060215  0.36
2006 Shore EM, Xu M, Feldman GJ, Fenstermacher DA, Cho TJ, Choi IH, Connor JM, Delai P, Glaser DL, LeMerrer M, Morhart R, Rogers JG, Smith R, Triffitt JT, Urtizberea JA, et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nature Genetics. 38: 525-7. PMID 16642017 DOI: 10.1038/ng1783  0.36
2005 Schaffer AA, Kaplan FS, Tracy MR, O'Brien ML, Dormans JP, Shore EM, Harland RM, Kusumi K. Developmental anomalies of the cervical spine in patients with fibrodysplasia ossificans progressiva are distinctly different from those in patients with Klippel-Feil syndrome: clues from the BMP signaling pathway. Spine. 30: 1379-85. PMID 15959366 DOI: 10.1097/01.brs.0000166619.22832.2c  0.36
2005 de la Peña LS, Billings PC, Fiori JL, Ahn J, Kaplan FS, Shore EM. Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1168-76. PMID 15940369 DOI: 10.1359/JBMR.050305  0.36
2005 Shore EM, Feldman GJ, Xu M, Kaplan FS. The genetics of fibrodysplasia ossificans progressiva Clinical Reviews in Bone and Mineral Metabolism. 3: 201-204. DOI: 10.1385/BMM:3:3-4:201  0.36
2005 Kaplan FS, Shore EM, Gupta R, Billings PC, Glaser DL, Pignolo RJ, Graf D, Kamoun M. Immunological features of fibrodysplasia ossificans progressiva and the dysregulated BMP4 pathway Clinical Reviews in Bone and Mineral Metabolism. 3: 189-193. DOI: 10.1385/BMM:3:3-4:189  0.36
2004 Scarlett RF, Rocke DM, Kantanie S, Patel JB, Shore EM, Kaplan FS. Influenza-like viral illnesses and flare-ups of fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research. 275-9. PMID 15232462  0.36
2004 Kaplan FS, Glaser DL, Hebela N, Shore EM. Heterotopic ossification. The Journal of the American Academy of Orthopaedic Surgeons. 12: 116-25. PMID 15089085  0.36
2003 Glaser DL, Economides AN, Wang L, Liu X, Kimble RD, Fandl JP, Wilson JM, Stahl N, Kaplan FS, Shore EM. In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification. The Journal of Bone and Joint Surgery. American Volume. 85: 2332-42. PMID 14668502 DOI: 10.2106/00004623-200312000-00010  0.36
2003 Hegyi L, Gannon FH, Glaser DL, Shore EM, Kaplan FS, Shanahan CM. Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification? The Journal of Pathology. 201: 141-8. PMID 12950027 DOI: 10.1002/path.1413  0.36
2003 Ahn J, Serrano de la Pena L, Shore EM, Kaplan FS. Paresis of a bone morphogenetic protein-antagonist response in a genetic disorder of heterotopic skeletogenesis. The Journal of Bone and Joint Surgery. American Volume. 85: 667-74. PMID 12672843  0.36
2003 Olmsted EA, Kaplan FS, Shore EM. Bone morphogenetic protein-4 regulation in fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research. 331-43. PMID 12616078  0.36
2003 Faust RA, Shore EM, Stevens CE, Xu M, Shah S, Phillips CD, Kaplan FS. Progressive osseous heteroplasia in the face of a child. American Journal of Medical Genetics. Part A. 118: 71-5. PMID 12605446 DOI: 10.1002/ajmg.a.10170  0.36
2003 Ahn J, Feldman G, Terry L, Shore EM, Kaplan FS. Exoneration of NF-kappaB dysregulation in fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research. 205-13. PMID 12579020 DOI: 10.1097/01.blo.0000030075.92399.11  0.36
2002 Xu MQ, Shore EM, Kaplan FS. Reported noggin mutations are PCR errors. American Journal of Medical Genetics. 109: 161; author reply 16. PMID 11977168 DOI: 10.1002/ajmg.10288  0.36
2002 Shore EM, Ahn J, Jan de Beur S, Li M, Xu M, Gardner RJ, Zasloff MA, Whyte MP, Levine MA, Kaplan FS. Paternally inherited inactivating mutations of the GNAS1 gene in progressive osseous heteroplasia. The New England Journal of Medicine. 346: 99-106. PMID 11784876 DOI: 10.1056/NEJMoa011262  0.36
2001 Gannon FH, Glaser D, Caron R, Thompson LD, Shore EM, Kaplan FS. Mast cell involvement in fibrodysplasia ossificans progressiva. Human Pathology. 32: 842-8. PMID 11521229 DOI: 10.1053/hupa.2001.26464  0.36
2001 Mahboubi S, Glaser DL, Shore EM, Kaplan FS. Fibrodysplasia ossificans progressiva. Pediatric Radiology. 31: 307-14. PMID 11379597 DOI: 10.1007/s002470100447  0.36
2000 Yeh GL, Mathur S, Wivel A, Li M, Gannon FH, Ulied A, Audi L, Olmsted EA, Kaplan FS, Shore EM. GNAS1 mutation and Cbfa1 misexpression in a child with severe congenital platelike osteoma cutis Journal of Bone and Mineral Research. 15: 2063-2073. PMID 11092389 DOI: 10.1359/JBMR.2000.15.11.2063  0.36
1999 Virdi AS, Shore EM, Oreffo ROC, Li M, Connor JM, Smith R, Kaplan FS, Triffitt JT. Phenotypic and molecular heterogeneity in fibrodysplasia ossificans progressiva Calcified Tissue International. 65: 250-255. PMID 10441661 DOI: 10.1007/s002239900693  0.36
1997 Gannon FH, Kaplan FS, Olmsted E, Finkel GC, Zasloff MA, Shore E. Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva Human Pathology. 28: 339-343. PMID 9042799 DOI: 10.1016/S0046-8177(97)90133-7  0.36
1992 Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS. A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7. Genomics. 14: 759-62. PMID 1427904 DOI: 10.1016/S0888-7543(05)80181-8  0.36
1990 Nelson WJ, Shore EM, Wang AZ, Hammerton RW. Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithelial cells Journal of Cell Biology. 110: 349-357. PMID 2153683 DOI: 10.1083/jcb.110.2.349  0.36
1987 Shore EM, Guild GM. Closely linked DNA elements control the expression of the Sgs-5 glue protein gene in Drosophila. Genes & Development. 1: 829-39. PMID 3123322 DOI: 10.1101/gad.1.8.829  0.36
1986 Shore EM, Guild GM. Larval salivary gland secretion proteins in Drosophila structural analysis of the Sgs-5 gene. Journal of Molecular Biology. 190: 149-58. PMID 3098981 DOI: 10.1016/0022-2836(86)90288-3  0.36
1984 Guild GM, Shore EM. Larval salivary gland secretion proteins in Drosophila. Identification and characterization of the Sgs-5 structural gene. Journal of Molecular Biology. 179: 289-314. PMID 6439875 DOI: 10.1016/0022-2836(84)90067-6  0.36
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