| Year |
Citation |
Score |
| 2021 |
Jog R, Chen G, Wang J, Leff T. Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. Physiological Reports. 9: e14991. PMID 34342168 DOI: 10.14814/phy2.14991 |
0.311 |
|
| 2018 |
Leff T, Stemmer P, Tyrrell J, Jog R. Diabetes and Exposure to Environmental Lead (Pb). Toxics. 6. PMID 30200608 DOI: 10.3390/Toxics6030054 |
0.685 |
|
| 2017 |
Tyrrell JB, Hafida S, Stemmer P, Adhami A, Leff T. Lead (Pb) exposure promotes diabetes in obese rodents. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 39: 221-226. PMID 27908418 DOI: 10.1016/J.Jtemb.2016.10.007 |
0.681 |
|
| 2014 |
Astapova O, Leff T. PPARγ mutations, lipodystrophy and diabetes. Hormone Molecular Biology and Clinical Investigation. 20: 63-70. PMID 25460295 DOI: 10.1515/Hmbci-2014-0033 |
0.694 |
|
| 2013 |
Subauste A, Das A, Li X, Elliot B, Evans C, El Azzouny M, Treutelaar M, Oral E, Leff T, Burant C. Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations. Diabetes 2012;61:2922-2931 Diabetes. 62: 998-998. DOI: 10.2337/Db13-Er03A |
0.311 |
|
| 2013 |
Manly A, Kern S, Solarewicz J, Sleiman N, Lucas S, Leff T, Cala S. Characterization of Cardiac Adiponectin Post-Translational Processing and Secretion Biophysical Journal. 104: 313a. DOI: 10.1016/J.Bpj.2012.11.1737 |
0.303 |
|
| 2012 |
Astapova O, Leff T. Adiponectin and PPARγ: cooperative and interdependent actions of two key regulators of metabolism. Vitamins and Hormones. 90: 143-62. PMID 23017715 DOI: 10.1016/B978-0-12-398313-8.00006-3 |
0.693 |
|
| 2012 |
Subauste AR, Das AK, Li X, Elliott BG, Elliot B, Evans C, El Azzouny M, Treutelaar M, Oral E, Leff T, Burant CF. Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations. Diabetes. 61: 2922-31. PMID 22872237 DOI: 10.2337/Db12-0004 |
0.366 |
|
| 2012 |
Campeau PM, Astapova O, Martins R, Bergeron J, Couture P, Hegele RA, Leff T, Gagné C. Clinical and molecular characterization of a severe form of partial lipodystrophy expanding the phenotype of PPARγ deficiency Journal of Lipid Research. 53: 1968-1978. PMID 22750678 DOI: 10.1194/Jlr.P025437 |
0.696 |
|
| 2012 |
Mottillo EP, Bloch AE, Leff T, Granneman JG. Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply. The Journal of Biological Chemistry. 287: 25038-48. PMID 22685301 DOI: 10.1074/Jbc.M112.374041 |
0.306 |
|
| 2010 |
Grimaldi B, Bellet MM, Katada S, Astarita G, Hirayama J, Amin RH, Granneman JG, Piomelli D, Leff T, Sassone-Corsi P. PER2 controls lipid metabolism by direct regulation of PPARγ. Cell Metabolism. 12: 509-20. PMID 21035761 DOI: 10.1016/J.Cmet.2010.10.005 |
0.418 |
|
| 2010 |
Amin RH, Mathews ST, Alli A, Leff T. Endogenously produced adiponectin protects cardiomyocytes from hypertrophy by a PPARgamma-dependent autocrine mechanism. American Journal of Physiology. Heart and Circulatory Physiology. 299: H690-8. PMID 20622112 DOI: 10.1152/Ajpheart.01032.2009 |
0.319 |
|
| 2010 |
Youm YH, Yang H, Amin R, Smith SR, Leff T, Dixit VD. Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution. Aging Cell. 9: 478-89. PMID 20374200 DOI: 10.1111/J.1474-9726.2010.00574.X |
0.302 |
|
| 2010 |
Amin RH, Mathews ST, Camp HS, Ding L, Leff T. Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 298: E28-37. PMID 19843873 DOI: 10.1152/Ajpendo.00446.2009 |
0.336 |
|
| 2007 |
Monajemi H, Zhang L, Li G, Jeninga EH, Cao H, Maas M, Brouwer CB, Kalkhoven E, Stroes E, Hegele RA, Leff T. Familial partial lipodystrophy phenotype resulting from a single-base mutation in deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma. The Journal of Clinical Endocrinology and Metabolism. 92: 1606-12. PMID 17299075 DOI: 10.1210/Jc.2006-1807 |
0.403 |
|
| 2007 |
Li G, Leff T. Altered promoter recycling rates contribute to dominant-negative activity of human peroxisome proliferator-activated receptor-gamma mutations associated with diabetes. Molecular Endocrinology (Baltimore, Md.). 21: 857-64. PMID 17227883 DOI: 10.1210/Me.2006-0401 |
0.412 |
|
| 2007 |
Leff T. AMP-activated protein kinase as a therapeutic target for diabetes Drug Discovery Today: Therapeutic Strategies. 4: 123-127. DOI: 10.1016/J.Ddstr.2007.08.002 |
0.374 |
|
| 2006 |
Francis GA, Li G, Casey R, Wang J, Cao H, Leff T, Hegele RA. Peroxisomal proliferator activated receptor-gamma deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3). Bmc Medical Genetics. 7: 3. PMID 16412238 DOI: 10.1186/1471-2350-7-3 |
0.353 |
|
| 2004 |
Hegele RA, Leff T. Unbuckling lipodystrophy from insulin resistance and hypertension. The Journal of Clinical Investigation. 114: 163-5. PMID 15254581 DOI: 10.1172/Jci22382 |
0.324 |
|
| 2004 |
Leff T, Mathews ST, Camp HS. Peroxisome proliferator-activated receptor-γ and its role in the development and treatment of diabetes Experimental Diabesity Research. 5: 99-109. PMID 15203881 DOI: 10.1080/15438600490451668 |
0.41 |
|
| 2003 |
Hong YH, Varanasi US, Yang W, Leff T. AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability. The Journal of Biological Chemistry. 278: 27495-501. PMID 12740371 DOI: 10.1074/Jbc.M304112200 |
0.396 |
|
| 2002 |
Hegele RA, Cao H, Frankowski C, Mathews ST, Leff T. PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy. Diabetes. 51: 3586-90. PMID 12453919 DOI: 10.2337/Diabetes.51.12.3586 |
0.399 |
|
| 2002 |
Camp HS, Ren D, Leff T. Adipogenesis and fat-cell function in obesity and diabetes Trends in Molecular Medicine. 8: 442-447. PMID 12223316 DOI: 10.1016/S1471-4914(02)02396-1 |
0.454 |
|
| 2000 |
Camp HS, Li O, Wise SC, Hong YH, Frankowski CL, Shen X, Vanbogelen R, Leff T. Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone. Diabetes. 49: 539-47. PMID 10871190 DOI: 10.2337/Diabetes.49.4.539 |
0.339 |
|
| 1996 |
Li WW, Dammerman MM, Smith JD, Metzger S, Breslow JL, Leff T. Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. The Journal of Clinical Investigation. 96: 2601-5. PMID 8675624 DOI: 10.1172/Jci118324 |
0.336 |
|
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