Valerie A. Galton - Publications

Affiliations: 
Dartmouth College, Hanover, NH, United States 
Area:
Molecular Biology, Oncology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Galton VA, Larsen PR, Berry MJ. The Deiodinases: their Identification and Cloning of their Genes. Endocrinology. PMID 33449107 DOI: 10.1210/endocr/bqab005  0.387
2020 Galton VA, Martinez ME, Dragon JA, St Germain DL, Hernandez A. The Intrinsic Activity of Thyroxine is Critical for Survival and Growth and Regulates Gene expression in Neonatal Liver. Thyroid : Official Journal of the American Thyroid Association. PMID 32791885 DOI: 10.1089/thy.2020.0508  0.415
2019 Morris JC, Galton VA. The isolation of thyroxine (T4), the discovery of 3,5,3'-triiodothyronine (T3), and the identification of the deiodinases that generate T3 from T4: An historical review. Endocrine. PMID 31256344 DOI: 10.1007/S12020-019-01990-1  0.479
2017 Citterio CE, Veluswamy B, Morgan SJ, Galton VA, Banga JP, Atkins S, Morishita Y, Neumann S, Latif R, Gershengorn MC, Smith TJ, Arvan P. De novo triiodothyronine formation from thyrocytes activated by Thyroid Stimulating Hormone. The Journal of Biological Chemistry. PMID 28743746 DOI: 10.1074/Jbc.M117.784447  0.561
2017 Galton VA. The ups and downs of the thyroxine pro-hormone hypothesis Molecular and Cellular Endocrinology. 458: 105-111. PMID 28130114 DOI: 10.1016/J.Mce.2017.01.029  0.543
2016 Liu J, Hernandez-Ono A, Graham MJ, Galton VA, Ginsberg HN. Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27150392 DOI: 10.1161/Atvbaha.116.307330  0.308
2016 Martinez ME, Karaczyn A, Patrizia Stohn J, Donnelly W, Croteau W, Peeters RP, Galton VA, Forrest D, Germain DS, Hernandez A. The Type 3 Deiodinase is a Critical Determinant of Appropriate Thyroid Hormone Action in the Developing Testis. Endocrinology. en20151910. PMID 26727108 DOI: 10.1210/En.2015-1910  0.439
2014 Galton VA, de Waard E, Parlow AF, St Germain DL, Hernandez A. Life without the iodothyronine deiodinases. Endocrinology. 155: 4081-7. PMID 24949664 DOI: 10.1210/En.2014-1184  0.456
2014 Galton VA, Hernandez A, St Germain DL. The 5'-deiodinases are not essential for the fasting-induced decrease in circulating thyroid hormone levels in male mice: possible roles for the type 3 deiodinase and tissue sequestration of hormone. Endocrinology. 155: 3172-81. PMID 24635350 DOI: 10.1210/En.2013-1884  0.567
2014 Bianco AC, Anderson G, Forrest D, Galton VA, Gereben B, Kim BW, Kopp PA, Liao XH, Obregon MJ, Peeters RP, Refetoff S, Sharlin DS, Simonides WS, Weiss RE, Williams GR, et al. American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models. Thyroid : Official Journal of the American Thyroid Association. 24: 88-168. PMID 24001133 DOI: 10.1089/Thy.2013.0109  0.388
2012 Buitendijk M, Galton VA. Is the Kidney a Major Storage Site for Thyroxine as Thyroxine Glucuronide Thyroid. 22: 187-191. PMID 22175240 DOI: 10.1089/Thy.2011.0307  0.503
2011 Liao XH, Di Cosmo C, Dumitrescu AM, Hernandez A, Van Sande J, St Germain DL, Weiss RE, Galton VA, Refetoff S. Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes. Endocrinology. 152: 1180-91. PMID 21285310 DOI: 10.1210/En.2010-0900  0.477
2010 Bassett JH, Boyde A, Howell PG, Bassett RH, Galliford TM, Archanco M, Evans H, Lawson MA, Croucher P, St Germain DL, Galton VA, Williams GR. Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts. Proceedings of the National Academy of Sciences of the United States of America. 107: 7604-9. PMID 20368437 DOI: 10.1073/Pnas.0911346107  0.451
2010 Morte B, Ceballos A, Diez D, Grijota-Martínez C, Dumitrescu AM, Di Cosmo C, Galton VA, Refetoff S, Bernal J. Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice. Endocrinology. 151: 2381-7. PMID 20211971 DOI: 10.1210/En.2009-0944  0.435
2009 Galton VA, Schneider MJ, Clark AS, St Germain DL. Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases. Endocrinology. 150: 2957-63. PMID 19196796 DOI: 10.1210/En.2008-1572  0.541
2009 St Germain DL, Galton VA, Hernandez A. Minireview: Defining the roles of the iodothyronine deiodinases: current concepts and challenges. Endocrinology. 150: 1097-107. PMID 19179439 DOI: 10.1210/En.2008-1588  0.41
2009 Ng L, Hernandez A, He W, Ren T, Srinivas M, Ma M, Galton VA, St Germain DL, Forrest D. A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology. 150: 1952-60. PMID 19095741 DOI: 10.1210/En.2008-1419  0.452
2007 Hernandez A, Martinez ME, Liao XH, Van Sande J, Refetoff S, Galton VA, St Germain DL. Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis. Endocrinology. 148: 5680-7. PMID 17823249 DOI: 10.1210/En.2007-0652  0.484
2007 Galton VA, Wood ET, St Germain EA, Withrow CA, Aldrich G, St Germain GM, Clark AS, St Germain DL. Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development. Endocrinology. 148: 3080-8. PMID 17332058 DOI: 10.1210/En.2006-1727  0.501
2006 Hernandez A, Martinez ME, Fiering S, Galton VA, St Germain D. Type 3 deiodinase is critical for the maturation and function of the thyroid axis. The Journal of Clinical Investigation. 116: 476-84. PMID 16410833 DOI: 10.1172/Jci26240  0.569
2006 Schneider MJ, Fiering SN, Thai B, Wu SY, St Germain E, Parlow AF, St Germain DL, Galton VA. Targeted disruption of the type 1 selenodeiodinase gene (Dio1) results in marked changes in thyroid hormone economy in mice. Endocrinology. 147: 580-9. PMID 16223863 DOI: 10.1210/En.2005-0739  0.543
2005 St Germain DL, Hernandez A, Schneider MJ, Galton VA. Insights into the role of deiodinases from studies of genetically modified animals. Thyroid : Official Journal of the American Thyroid Association. 15: 905-16. PMID 16131333 DOI: 10.1089/Thy.2005.15.905  0.371
2005 Galton VA. The roles of the iodothyronine deiodinases in mammalian development. Thyroid. 15: 823-834. PMID 16131325 DOI: 10.1089/Thy.2005.15.823  0.379
2004 Ng L, Goodyear RJ, Woods CA, Schneider MJ, Diamond E, Richardson GP, Kelley MW, Germain DL, Galton VA, Forrest D. Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase. Proceedings of the National Academy of Sciences of the United States of America. 101: 3474-9. PMID 14993610 DOI: 10.1073/Pnas.0307402101  0.491
2003 Wasco EC, Martinez E, Grant KS, St Germain EA, St Germain DL, Galton VA. Determinants of iodothyronine deiodinase activities in rodent uterus. Endocrinology. 144: 4253-61. PMID 12959985 DOI: 10.1210/En.2003-0490  0.393
2002 Hernandez A, Fiering S, Martinez E, Galton VA, St Germain D. The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts. Endocrinology. 143: 4483-6. PMID 12399446 DOI: 10.1210/En.2002-220800  0.303
2001 Schneider MJ, Fiering SN, Pallud SE, Parlow AF, St. Germain DL, Galton VA. Targeted disruption of the type 2 selenodeiodinase gene (Dio2) results in a phenotype of pituitary resistance to T4 Molecular Endocrinology. 15: 2137-2148. PMID 11731615 DOI: 10.1210/Mend.15.12.0740  0.545
2001 Galton VA, Martinez E, Hernandez A, St Germain EA, Bates JM, St Germain DL. The type 2 iodothyronine deiodinase is expressed in the rat uterus and induced during pregnancy. Endocrinology. 142: 2123-8. PMID 11316780 DOI: 10.1210/Endo.142.5.8169  0.436
2000 Wu SY, Huang WS, Fisher DA, Florsheim WH, St Germain DL, Galton VA. Iodothyronine sulfotransferase activity in rat uterus during gestation. Pediatric Research. 48: 847-51. PMID 11102557 DOI: 10.1203/00006450-200012000-00024  0.513
2000 Bates JM, Spate VL, Morris JS, St Germain DL, Galton VA. Effects of selenium deficiency on tissue selenium content, deiodinase activity, and thyroid hormone economy in the rat during development. Endocrinology. 141: 2490-500. PMID 10875250 DOI: 10.1210/Endo.141.7.7571  0.526
1999 Galton VA, Martinez E, Hernandez A, St Germain EA, Bates JM, St Germain DL. Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinase. The Journal of Clinical Investigation. 103: 979-87. PMID 10194470 DOI: 10.1172/Jci6073  0.407
1999 Davey JC, Schneider MJ, Becker KB, Galton VA. Cloning of a 5.8 kb cDNA for a mouse type 2 deiodinase Endocrinology. 140: 1022-1025. PMID 9927339 DOI: 10.1210/Endo.140.2.6678  0.301
1999 Bates JM, St Germain DL, Galton VA. Expression profiles of the three iodothyronine deiodinases, D1, D2, and D3, in the developing rat. Endocrinology. 140: 844-51. PMID 9927314 DOI: 10.1210/Endo.140.2.6537  0.485
1999 Germain DLS, Galton VA, Bates J, Croteau W, Davey J, Hernandez A, Martinez E, Schneider MJ. Deiodinase Protection Of The Fetus From Thyroid Hormones Biochemical Society Transactions. 27. DOI: 10.1042/Bst027A006B  0.398
1997 St Germain DL, Galton VA. The deiodinase family of selenoproteins. Thyroid : Official Journal of the American Thyroid Association. 7: 655-68. PMID 9292958 DOI: 10.1089/Thy.1997.7.655  0.334
1996 Croteau W, Davey JC, Galton VA, St Germain DL. Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues. The Journal of Clinical Investigation. 98: 405-17. PMID 8755651 DOI: 10.1172/Jci118806  0.41
1995 Schneider MJ, Galton VA. Effect of glucocorticoids on thyroid hormone action in cultured red blood cells from Rana catesbeiana tadpoles Endocrinology. 136: 1435-1440. PMID 7895654 DOI: 10.1210/Endo.136.4.7895654  0.45
1995 Becker KB, Schneider MJ, Davey JC, Galton VA. The type III 5-deiodinase in Rana catesbeiana tadpoles is encoded by a thyroid hormone-responsive gene Endocrinology. 136: 4424-4431. PMID 7664662 DOI: 10.1210/Endo.136.10.7664662  0.504
1994 St Germain DL, Schwartzman RA, Croteau W, Kanamori A, Wang Z, Brown DD, Galton VA. A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase. Proceedings of the National Academy of Sciences of the United States of America. 91: 7767-71. PMID 8052658 DOI: 10.1073/Pnas.91.16.7767  0.419
1994 St Germain DL, Schwartzman RA, Croteau W, Kanamori A, Wang Z, Brown DD, Galton VA. A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase. Proceedings of the National Academy of Sciences of the United States of America. 91: 11282. PMID 7972049 DOI: 10.1073/Pnas.91.23.11282  0.381
1994 Davey JC, Schneider MJ, Galton VA. Cloning of a thyroid hormone-responsive Rana catesbeiana c-erbA-β gene Developmental Genetics. 15: 339-346. PMID 7923937 DOI: 10.1002/Dvg.1020150405  0.388
1993 Schneider MJ, Davey JC, Galton VA. Rana catesbeiana tadpole red blood cells express an α, but not a β, c- erbA gene Endocrinology. 133: 2488-2495. PMID 8243269 DOI: 10.1210/Endo.133.6.8243269  0.38
1992 Galton VA. Thyroid hormone receptors and iodothyronine deiodinases in the developing Mexican axolotl, Ambystoma mexicanum. General and Comparative Endocrinology. 85: 62-70. PMID 1563619 DOI: 10.1016/0016-6480(92)90172-G  0.538
1991 Galton VA, McCarthy PT, St Germain DL. The ontogeny of iodothyronine deiodinase systems in liver and intestine of the rat. Endocrinology. 128: 1717-22. PMID 2004598 DOI: 10.1210/Endo-128-4-1717  0.39
1991 Galton VA, Morganelli CM, Schneider MJ, Yee K. The role of thyroid hormone in the regulation of hepatic carbamyl phosphate synthetase activity in Rana catesbeiana. Endocrinology. 129: 2298-304. PMID 1935768 DOI: 10.1210/Endo-129-5-2298  0.494
1991 Schneider MJ, Galton VA. Regulation of c-erbA-α messenger RNA species in tadpole erythrocytes by thyroid hormone Molecular Endocrinology. 5: 201-208. PMID 1645454 DOI: 10.1210/Mend-5-2-201  0.402
1990 Galton VA. Mechanisms Underlying the Acceleration of Thyroid Hormone-Induced Tadpole Metamorphosis by Corticosterone* Endocrinology. 127: 2997-3002. PMID 2249638 DOI: 10.1210/Endo-127-6-2997  0.515
1988 Galton VA, Hiebert A. The Ontogeny of Iodothyronine 5'-Monodeiodinase Activity in Rana catesbeiana Tadpoles Endocrinology. 122: 640-645. PMID 3257441 DOI: 10.1210/Endo-122-2-640  0.491
1988 Galton VA. The Role of Thyroid Hormone in Amphibian Development Integrative and Comparative Biology. 28: 309-318. DOI: 10.1093/Icb/28.2.309  0.53
1987 Galton VA, Hiebert A. The ontogeny of the enzyme systems for the 5'- and 5-deiodination of thyroid hormones in chick embryo liver. Endocrinology. 120: 2604-2610. PMID 3569147 DOI: 10.1210/Endo-120-6-2604  0.534
1987 Galton VA, Hiebert A. Hepatic iodothyronine 5-deiodinase activity in Rana catesbeiana tadpoles at different stages of the life cycle. Endocrinology. 121: 42-47. PMID 3496211 DOI: 10.1210/Endo-121-1-42  0.527
1986 Galton VA, Germain St. DL, Whittemore S. Cellular uptake of 3,5,3'-triiodothyronine and thyroxine by red blood and thymus cells Endocrinology. 118: 1918-1923. PMID 3486116 DOI: 10.1210/Endo-118-5-1918  0.495
1986 Galton VA. Thyroxine and 3,5,3′-Triiodothyronine Bind to the Same Putative Receptor in Hepatic Nuclei of Rana catesbeiana Tadpoles Endocrinology. 118: 1114-1118. PMID 3004895 DOI: 10.1210/Endo-118-3-1114  0.479
1985 St Germain DL, Adler RA, Galton VA. Thyroxine 5'-deiodinase activity in anterior pituitary glands transplanted under the renal capsule in the rat. Endocrinology. 117: 55-63. PMID 4006866 DOI: 10.1210/Endo-117-1-55  0.495
1985 Galton VA. 3,5,3′-Triiodothyronine receptors and thyroxine 5′-monodeiodinating activity in thyroid hormone-insensitive Amphibia ☆ General and Comparative Endocrinology. 57: 465-471. PMID 2985464 DOI: 10.1016/0016-6480(85)90229-1  0.437
1985 St Germain DL, Galton VA. Comparative study of pituitary-thyroid hormone economy in fasting and hypothyroid rats. The Journal of Clinical Investigation. 75: 679-88. PMID 2982916 DOI: 10.1172/Jci111747  0.565
1984 Galton VA. Putative Nuclear Triiodothyronine Receptors in Tadpole Erythrocytes: Regulation of Receptor Number by Thyroid Hormone Endocrinology. 114: 735-742. PMID 6321136 DOI: 10.1210/Endo-114-3-735  0.396
1983 Galton VA, Schaafsma J. Binding of thyroid hormones to isolated hepatic nuclei from Rana catesbeiana tadpoles. Endocrinology. 112: 1999-2006. PMID 6303753 DOI: 10.1210/Endo-112-6-1999  0.491
1981 Galton VA, Munck K. Metabolism of thyroxine in Rana catesbeiana tadpoles during metamorphic climax. Endocrinology. 109: 1127-1131. PMID 6974641 DOI: 10.1210/Endo-109-4-1127  0.506
1980 Galton VA, Cohen JS. Action of thyroid hormones in premetamorphic tadpoles: an important role for thyroxine? Endocrinology. 107: 1820-1826. PMID 6968674 DOI: 10.1210/Endo-107-6-1820  0.54
1980 Galton VA. Binding of Thyroid Hormones in Vivo by Hepatic Nuclei of Rana catesbeiana Tadpoles at Different Stages of Metamorphosis Endocrinology. 107: 1910-1915. PMID 6253280 DOI: 10.1210/Endo-107-6-1910  0.413
1980 Galton VA. Binding of thyroid hormones in serum and liver cytosol of Rana catesbeiana tadpoles. Endocrinology. 107: 61-69. PMID 6247146 DOI: 10.1210/Endo-107-1-61  0.514
1980 Galton VA. Binding of thyroid hormones in vivo by hepatic nuclei of Rana catesbeiana tadpoles. Endocrinology. 106: 859-866. PMID 6243554 DOI: 10.1210/Endo-106-3-859  0.521
1978 Silverstone M, Galton VA, Ingbar SH. Observations concerning the metabolism of iodine by polyps of Aurelia aurita. General and Comparative Endocrinology. 34: 132-140. PMID 24574 DOI: 10.1016/0016-6480(78)90203-4  0.477
1977 Robinson H, Chaffee S, Galton VA. The sensitivity of Xenopus laevis tadpole tail tissue to the action of thyroid hormones. General and Comparative Endocrinology. 32: 179-86. PMID 892410 DOI: 10.1016/0016-6480(77)90149-6  0.504
1977 Nisula BC, Galton VA, Ingbar SH. A new method for the assessment of thyroxine metabolism in the rat. Endocrinology. 100: 1432-1436. PMID 849734 DOI: 10.1210/Endo-100-5-1432  0.469
1976 Robinson H, Galton VA. Studies on the deiodination of thyroid hormones in Xenopus laevis tadpoles. General and Comparative Endocrinology. 30: 83-90. PMID 992332 DOI: 10.1016/0016-6480(76)90069-1  0.529
1975 Ingbar DH, Galton VA. The Effect of Food Deprivation on the Peripheral Metabolism of Thyroxine in Rats Endocrinology. 96: 1525-1532. PMID 1126320 DOI: 10.1210/Endo-96-6-1525  0.533
1972 Galton VA, Ingbar SH. Decrease in the Thyroidal Internal Iodide Pool Induced by 3-Nitro-L-Tyrosine (MNT), an Inhibitor of Iodotyrosine Deiodination Endocrinology. 91: 1476-1480. PMID 5086139 DOI: 10.1210/Endo-91-6-1476  0.405
1972 Galton VA. Some Effects of Altitude on Thyroid Function Endocrinology. 91: 1393-1403. PMID 4343729 DOI: 10.1210/Endo-91-6-1393  0.514
1971 Galton VA. Thyroxine Metabolism and Thyroid Function in Rats Following Administration of Estrogen1 Endocrinology. 88: 976-982. PMID 5542424 DOI: 10.1210/Endo-88-4-976  0.541
1971 Dawber NA, Galton VA, Ingbar SH. Degradation of Thyroxine by a Thyroidal Peroxidase1 Endocrinology. 88: 144-148. PMID 5538547 DOI: 10.1210/Endo-88-1-144  0.502
1969 Galton VA, Nisula BC. Thyroxine metabolism and thyroid function in the cold-adapted rat. Endocrinology. 85: 79-86. PMID 5786353 DOI: 10.1210/Endo-85-1-79  0.553
1968 Galton VA. Thyroxine metabolism and thyroid function in the pregnant rat. Endocrinology. 82: 282-290. PMID 4951277 DOI: 10.1210/Endo-82-2-282  0.515
1967 Galton VA, Ingbar SH. Effect of large doses of iodide on the peripheral metabolism of thyroxine in rats. Endocrinology. 81: 1439-1441. PMID 6080097 DOI: 10.1210/Endo-81-6-1439  0.456
1966 Galton VA, Valtin H, Johnson DG. Thyroid Function in the Absence of Vasopressin1 Endocrinology. 78: 1224-1229. PMID 5920699 DOI: 10.1210/Endo-78-6-1224  0.461
1966 Galton VA, Ingbar SH. Observations on the nature of the heat-resistant thyroxine deiodinating system of rat liver. Endocrinology. 78: 855-859. PMID 5904944 DOI: 10.1210/Endo-78-4-855  0.316
1966 Galton VA, Ingbar SH. Effect of a malignant tumor on thyroxine metabolism and thyroid function in the rat. Endocrinology. 79: 964-970. PMID 4162728 DOI: 10.1210/Endo-79-5-964  0.419
1966 Nagataki S, Mizuno M, Sakamoto S, Irie M, Shizume K, Nakao K, Galton VA, Arky RA, Ingbar SH. Thyroid Function in Molar Pregnancy The Journal of Clinical Endocrinology and Metabolism. 44: 254-263. PMID 402378 DOI: 10.1210/Jcem-44-2-254  0.507
1965 Galton VA, Ingbar SH, Heyde SVD. Role Of Catalases And Peroxidases In The Deiodination Of Thyroxine In Frog Liver. Endocrinology. 76: 479-485. PMID 14263285 DOI: 10.1210/Endo-76-3-479  0.387
1965 Galton VA. Thyroid Hormone-Catecholamine Interrelationships Endocrinology. 77: 278-284. PMID 5836169 DOI: 10.1210/Endo-77-2-278  0.511
1965 Galton VA, Ingbar SH. Effects of Vitamin Deficiency on the in Vitro and in Vivo Deiodination of Thyroxine in the Rat Endocrinology. 77: 169-176. DOI: 10.1210/Endo-77-1-169  0.43
1964 Galton VA, Ingbar SH. Effect Of Catalase Inhibitors On The Deiodination Of Thyroxine. Endocrinology. 74: 627-634. PMID 14183208 DOI: 10.1210/Endo-74-4-627  0.508
1963 Galton VA, Ingbar SH. Role Of Peroxidase And Catalase In The Physiological Deiodination Of Thyroxine. Endocrinology. 73: 596-605. PMID 14082995 DOI: 10.1210/Endo-73-5-596  0.46
1962 Galton VA, Ingbar SH. Observations on the relation between the action and the degradation of thyroid hormones as indicated by studies in the tadpole and the frog. Endocrinology. 70: 622-632. PMID 13896498 DOI: 10.1210/Endo-70-5-622  0.402
1961 Galton VA, Ingbar SH. The Mechanism Of Protein Iodination During The Metabolism Of Thyroid Hormones By Peripheral Tissues Endocrinology. 69: 30-38. PMID 13703211 DOI: 10.1210/Endo-69-1-30  0.328
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