Srinivas Rapireddy - Publications

Affiliations: 
Chemistry Carnegie Mellon University, Pittsburgh, PA 

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Nölling J, Rapireddy S, Amburg JI, Crawford EM, Prakash RA, Rabson AR, Tang YW, Singer A. Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood. Mbio. 7. PMID 27094328 DOI: 10.1128/Mbio.00345-16  0.375
2015 Manna A, Rapireddy S, Sureshkumar G, Ly DH. Synthesis of optically pure γPNA monomers: a comparative study. Tetrahedron. 71: 3507-3514. PMID 30792557 DOI: 10.1016/J.Tet.2015.03.052  0.631
2014 Manna A, Rapireddy S, Bahal R, Ly DH. MiniPEG-γPNA. Methods in Molecular Biology (Clifton, N.J.). 1050: 1-12. PMID 24297346 DOI: 10.1007/978-1-62703-553-8_1  0.684
2013 Thomas SM, Sahu B, Rapireddy S, Bahal R, Wheeler SE, Procopio EM, Kim J, Joyce SC, Contrucci S, Wang Y, Chiosea SI, Lathrop KL, Watkins S, Grandis JR, Armitage BA, et al. Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models. Acs Chemical Biology. 8: 345-52. PMID 23113581 DOI: 10.1021/Cb3003946  0.671
2012 Sen M, Thomas SM, Kim S, Yeh JI, Ferris RL, Johnson JT, Duvvuri U, Lee J, Sahu N, Joyce S, Freilino ML, Shi H, Li C, Ly D, Rapireddy S, et al. First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discovery. 2: 694-705. PMID 22719020 DOI: 10.1158/2159-8290.Cd-12-0191  0.61
2012 Wierzbinski E, de Leon A, Yin X, Balaeff A, Davis KL, Rapireddy S, Reppireddy S, Venkatramani R, Keinan S, Ly DH, Madrid M, Beratan DN, Achim C, Waldeck DH. Effect of backbone flexibility on charge transfer rates in peptide nucleic acid duplexes. Journal of the American Chemical Society. 134: 9335-42. PMID 22548314 DOI: 10.1021/Ja301677Z  0.62
2012 Singer A, Rapireddy S, Ly DH, Meller A. Electronic barcoding of a viral gene at the single-molecule level. Nano Letters. 12: 1722-8. PMID 22352964 DOI: 10.1021/Nl300372A  0.628
2012 Rapireddy S, Nhon L, Meehan RE, Franks J, Stolz DB, Tran D, Selsted ME, Ly DH. RTD-1mimic containing γPNA scaffold exhibits broad-spectrum antibacterial activities. Journal of the American Chemical Society. 134: 4041-4. PMID 22332599 DOI: 10.1021/Ja211867J  0.632
2012 Bahal R, Sahu B, Rapireddy S, Lee CM, Ly DH. Sequence-unrestricted, Watson-Crick recognition of double helical B-DNA by (R)-miniPEG-γPNAs. Chembiochem : a European Journal of Chemical Biology. 13: 56-60. PMID 22135012 DOI: 10.1002/Cbic.201100646  0.658
2012 Wierzbinski E, de Leon A, Yin X, Balaeff A, Davis KL, Rapireddy S, Venkatramani R, Keinan S, Ly DH, Madrid M, Beratan DN, Achim C, Waldeck DH. Correction to Effect of Backbone Flexibility on Charge Transfer Rates in Peptide Nucleic Acid Duplexes Journal of the American Chemical Society. 134: 13141-13141. DOI: 10.1021/Ja306598Z  0.656
2011 Bezer S, Rapireddy S, Skorik YA, Ly DH, Achim C. Coordination-driven inversion of handedness in ligand-modified PNA. Inorganic Chemistry. 50: 11929-37. PMID 22059624 DOI: 10.1021/Ic200855P  0.661
2011 Crawford MJ, Rapireddy S, Bahal R, Sacui I, Ly DH. Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. Journal of Nucleic Acids. 2011: 652702. PMID 21776375 DOI: 10.4061/2011/652702  0.677
2011 Sahu B, Sacui I, Rapireddy S, Zanotti KJ, Bahal R, Armitage BA, Ly DH. Synthesis and characterization of conformationally preorganized, (R)-diethylene glycol-containing γ-peptide nucleic acids with superior hybridization properties and water solubility. The Journal of Organic Chemistry. 76: 5614-27. PMID 21619025 DOI: 10.1021/Jo200482D  0.698
2011 Rapireddy S, Bahal R, Ly DH. Strand invasion of mixed-sequence, double-helical B-DNA by γ-peptide nucleic acids containing G-clamp nucleobases under physiological conditions. Biochemistry. 50: 3913-8. PMID 21476606 DOI: 10.1021/Bi2002554  0.723
2010 Kuhn H, Sahu B, Rapireddy S, Ly DH, Frank-Kamenetskii MD. Sequence specificity at targeting double-stranded DNA with a γ-PNA oligomer modified with guanidinium G-clamp nucleobases. Artificial Dna, Pna & Xna. 1: 45-53. PMID 21687526 DOI: 10.4161/adna.1.1.12444  0.671
2010 Yeh JI, Shivachev B, Rapireddy S, Crawford MJ, Gil RR, Du S, Madrid M, Ly DH. Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. Journal of the American Chemical Society. 132: 10717-27. PMID 20681704 DOI: 10.1021/Ja907225D  0.677
2010 He W, Crawford MJ, Rapireddy S, Madrid M, Gil RR, Ly DH, Achim C. The structure of a gamma-modified peptide nucleic acid duplex. Molecular Biosystems. 6: 1619-29. PMID 20386807 DOI: 10.1039/C002254C  0.663
2010 Sen M, Thomas SM, Ly D, Rapireddy S, Grandis JR. Abstract 4139: Development of a transcription factor decoy for efficient systemic administration in head and neck cancer Cancer Research. 70: 4139-4139. DOI: 10.1158/1538-7445.Am10-4139  0.635
2009 He G, Rapireddy S, Bahal R, Sahu B, Ly DH. Strand invasion of extended, mixed-sequence B-DNA by gammaPNAs. Journal of the American Chemical Society. 131: 12088-90. PMID 19663424 DOI: 10.1021/Ja900228J  0.702
2008 Chenna V, Rapireddy S, Sahu B, Ausin C, Pedroso E, Ly DH. A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA. Chembiochem : a European Journal of Chemical Biology. 9: 2388-91. PMID 18816545 DOI: 10.1002/Cbic.200800441  0.698
2007 Rapireddy S, He G, Roy S, Armitage BA, Ly DH. Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA). Journal of the American Chemical Society. 129: 15596-600. PMID 18027941 DOI: 10.1021/Ja074886J  0.724
2006 Dragulescu-Andrasi A, Rapireddy S, He G, Bhattacharya B, Hyldig-Nielsen JJ, Zon G, Ly DH. Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects. Journal of the American Chemical Society. 128: 16104-12. PMID 17165763 DOI: 10.1021/Ja063383V  0.667
2006 Dragulescu-Andrasi A, Rapireddy S, Frezza BM, Gayathri C, Gil RR, Ly DH. A simple gamma-backbone modification preorganizes peptide nucleic acid into a helical structure. Journal of the American Chemical Society. 128: 10258-67. PMID 16881656 DOI: 10.1021/Ja0625576  0.713
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