| Year |
Citation |
Score |
| 2024 |
Dayan Elshan NGR, Wolff KC, Riva L, Woods AK, Grabovyi G, Wilson K, Pedroarena J, Ghorai S, Nazarian A, Weiss F, Liu Y, Mazumdar W, Song L, Okwor N, Malvin J, ... ... Joseph SB, et al. Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead. Journal of Medicinal Chemistry. PMID 38335279 DOI: 10.1021/acs.jmedchem.3c01938 |
0.406 |
|
| 2023 |
Grzelak EM, Elshan NGRD, Shao S, Bulos ML, Joseph SB, Chatterjee AK, Chen JJ, Nguyên-Trân V, Schultz PG, Bollong MJ. Pharmacological YAP activation promotes regenerative repair of cutaneous wounds. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305085120. PMID 37399395 DOI: 10.1073/pnas.2305085120 |
0.346 |
|
| 2021 |
Lee SC, Ma JSY, Kim MS, Laborda E, Choi SH, Hampton EN, Yun H, Nunez V, Muldong MT, Wu CN, Ma W, Kulidjian AA, Kane CJ, Klyushnichenko V, Woods AK, ... Joseph SB, et al. A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand. Science Advances. 7. PMID 34380625 DOI: 10.1126/sciadv.abi8193 |
0.446 |
|
| 2021 |
Bakowski MA, Beutler N, Wolff KC, Kirkpatrick MG, Chen E, Nguyen TH, Riva L, Shaabani N, Parren M, Ricketts J, Gupta AK, Pan K, Kuo P, Fuller M, Garcia E, ... ... Joseph SB, et al. Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nature Communications. 12: 3309. PMID 34083527 DOI: 10.1038/s41467-021-23328-0 |
0.404 |
|
| 2020 |
Lear S, Pflimlin E, Zhou Z, Huang D, Weng S, Nguyen-Tran V, Joseph SB, Roller S, Peterson S, Li J, Tremblay M, Schultz PG, Shen W. Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. Journal of Medicinal Chemistry. PMID 32844654 DOI: 10.1021/Acs.Jmedchem.0C00740 |
0.367 |
|
| 2020 |
Chin EN, Yu C, Vartabedian VF, Jia Y, Kumar M, Gamo AM, Vernier W, Ali SH, Kissai M, Lazar DC, Nguyen N, Pereira LE, Benish B, Woods AK, Joseph SB, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999. PMID 32820126 DOI: 10.1126/Science.Abb4255 |
0.486 |
|
| 2020 |
Johnson K, Woods A, Joseph S, Chatterjee A, Zhu S, Wisler J, Klyushnichenko V, Li J, Lotz M, Tremblay M, Schultz P. Development of KA34 as a cartilage regenerative therapy for Osteoarthritis Osteoarthritis and Cartilage. 28: S518. DOI: 10.1016/J.Joca.2020.02.814 |
0.301 |
|
| 2019 |
Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, Yu S, Zhu S, Baguley TD, Surakattula M, Oetjen J, Hauberg-Lotte L, Herranz R, Awal S, Altenhofen D, ... ... Joseph S, et al. Neratinib protects pancreatic beta cells in diabetes. Nature Communications. 10: 5015. PMID 31676778 DOI: 10.1038/S41467-019-12880-5 |
0.359 |
|
| 2019 |
Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, ... ... Joseph SB, et al. Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections. Science Translational Medicine. 11. PMID 31068442 DOI: 10.1126/Scitranslmed.Aav3523 |
0.409 |
|
| 2018 |
Mandikian D, Figueroa I, Oldendorp A, Rafidi H, Ulufatu S, Schweiger MG, Couch JA, Dybdal N, Joseph SB, Prabhu S, Ferl GZ, Boswell CA. Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology. The Aaps Journal. 20: 107. PMID 30298434 DOI: 10.1208/S12248-018-0264-Z |
0.644 |
|
| 2018 |
Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, et al. The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. 115: 10750-10755. PMID 30282735 DOI: 10.1073/Pnas.1810137115 |
0.45 |
|
| 2018 |
Mandikian D, Takahashi N, Lo AA, Li J, Eastham-Anderson J, Slaga D, Ho J, Hristopoulos M, Clark R, Totpal K, Lin K, Joseph SB, Dennis MS, Prabhu S, Junttila TT, et al. Relative Target Affinities of T Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model. Molecular Cancer Therapeutics. PMID 29339550 DOI: 10.1158/1535-7163.Mct-17-0657 |
0.639 |
|
| 2017 |
Tully DC, Rucker PV, Chianelli D, Williams J, Vidal A, Alper PB, Mutnick D, Bursulaya B, Schmeits J, Wu X, Bao D, Zoll J, Kim Y, Groessl T, McNamara P, ... ... Joseph SB, et al. Discovery of Tropifexor (LJN452), a Highly Potent Non-Bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH). Journal of Medicinal Chemistry. PMID 29148806 DOI: 10.1021/Acs.Jmedchem.7B00907 |
0.301 |
|
| 2016 |
Wang RE, Wang Y, Zhang Y, Gabrelow C, Zhang Y, Chi V, Fu Q, Luo X, Wang D, Joseph S, Johnson K, Chatterjee AK, Wright TM, Nguyen-Tran VT, Teijaro J, et al. Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant. Proceedings of the National Academy of Sciences of the United States of America. 113: 11501-11506. PMID 27663736 DOI: 10.1073/Pnas.1612803113 |
0.502 |
|
| 2016 |
Gadkar K, Yadav DB, Zuchero JY, Couch JA, Kanodia J, Kenrick MK, Atwal JK, Dennis MS, Prabhu S, Watts RJ, Joseph SB, Ramanujan S. Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 26820920 DOI: 10.1016/J.Ejpb.2016.01.009 |
0.662 |
|
| 2015 |
Dickmann LJ, Yip V, Li C, Abundes J, Maia M, Young C, Stainton S, Hass PE, Joseph SB, Prabhu S, Boswell CA. Evaluation of Fluorophotometry to Assess the Vitreal Pharmacokinetics of Protein Therapeutics. Investigative Ophthalmology & Visual Science. 56: 6991-9. PMID 26513505 DOI: 10.1167/Iovs.15-17457 |
0.574 |
|
| 2015 |
Bumbaca Yadav D, Sharma VK, Boswell CA, Hotzel I, Tesar D, Shang Y, Ying Y, Fischer SK, Grogan JL, Chiang EY, Urban K, Ulufatu S, Khawli LA, Prabhu S, Joseph S, et al. Evaluating the use of antibody variable region (Fv) charge as a risk assessment tool for predicting typical cynomolgus monkey pharmacokinetics. The Journal of Biological Chemistry. PMID 26491012 DOI: 10.1074/Jbc.M115.692434 |
0.61 |
|
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