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Mahesh UTTAMCHANDANI - Publications

Affiliations: 
2007-2010 Chemistry National University of Singapore, Singapore, Singapore 
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Year Citation  Score
2017 Na Z, Pan S, Uttamchandani M, Yao SQ. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods in Molecular Biology (Clifton, N.J.). 1518: 139-156. PMID 27873205 DOI: 10.1007/978-1-4939-6584-7_10  0.758
2017 Sieow BF, Uttamchandani M. Array-on-Array Strategy For Activity-Based Enzyme Profiling. Methods in Molecular Biology (Clifton, N.J.). 1518: 131-138. PMID 27873204 DOI: 10.1007/978-1-4939-6584-7_9  0.375
2017 Uttamchandani M, Yao SQ. The Expanding World of Small Molecule Microarrays. Methods in Molecular Biology (Clifton, N.J.). 1518: 1-17. PMID 27873196 DOI: 10.1007/978-1-4939-6584-7_1  0.663
2015 Fu J, Na Z, Peng B, Uttamchandani M, Yao SQ. Accelerated cellular on- and off-target screening of bioactive compounds using microarrays. Organic & Biomolecular Chemistry. PMID 26584520 DOI: 10.1039/C5Ob02233A  0.798
2015 Yu C, Qian L, Uttamchandani M, Li L, Yao SQ. Single-Vehicular Delivery of Antagomir and Small Molecules to Inhibit miR-122 Function in Hepatocellular Carcinoma Cells by using "Smart" Mesoporous Silica Nanoparticles. Angewandte Chemie (International Ed. in English). 54: 10574-8. PMID 26179591 DOI: 10.1002/Anie.201504913  0.774
2015 Yu C, Qian L, Uttamchandani M, Li L, Yao SQ. Single-Vehicular Delivery of Antagomir and Small Molecules to Inhibit miR-122 Function in Hepatocellular Carcinoma Cells by using "smart" Mesoporous Silica Nanoparticles Angewandte Chemie - International Edition. 54: 10574-10578. DOI: 10.1002/anie.201504913  0.756
2014 Na Z, Pan S, Uttamchandani M, Yao SQ. Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray. Angewandte Chemie (International Ed. in English). 53: 8421-6. PMID 24961672 DOI: 10.1002/Anie.201405169  0.74
2014 Cheng X, Li L, Uttamchandani M, Yao SQ. In situ proteome profiling of C75, a covalent bioactive compound with potential anticancer activities. Organic Letters. 16: 1414-7. PMID 24552542 DOI: 10.1021/Ol500206W  0.77
2014 Cheng X, Li L, Uttamchandani M, Yao SQ. A tuned affinity-based staurosporine probe for in situ profiling of protein kinases. Chemical Communications (Cambridge, England). 50: 2851-3. PMID 24496501 DOI: 10.1039/C4Cc00184B  0.782
2013 Zhang CJ, Tan CY, Ge J, Na Z, Chen GY, Uttamchandani M, Sun H, Yao SQ. Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains. Angewandte Chemie (International Ed. in English). 52: 14060-4. PMID 24353229 DOI: 10.1002/Anie.201307803  0.805
2013 Neo JL, Uttamchandani M. Visual DNA detection and SNP genotyping using asymmetric PCR and split DNA enzymes. Methods in Molecular Biology (Clifton, N.J.). 1039: 141-51. PMID 24026693 DOI: 10.1007/978-1-62703-535-4_12  0.315
2013 Fu J, Na Z, Uttamchandani M, Yao SQ. Profiling human Src homology 2 (SH2) domain proteins and ligand discovery using a peptide-hybrid small molecule microarray. Chemical Communications (Cambridge, England). 49: 9660-2. PMID 24022784 DOI: 10.1039/C3Cc45413D  0.806
2013 Kalidasan K, Su Y, Wu X, Yao SQ, Uttamchandani M. Fluorescence-activated cell sorting and directed evolution of α-N-acetylgalactosaminidases using a quenched activity-based probe (qABP). Chemical Communications (Cambridge, England). 49: 7237-9. PMID 23842736 DOI: 10.1039/C3Cc42836B  0.749
2013 Gao L, Sun H, Uttamchandani M, Yao SQ. Phosphopeptide microarrays for comparative proteomic profiling of cellular lysates. Methods in Molecular Biology (Clifton, N.J.). 1002: 233-51. PMID 23625408 DOI: 10.1007/978-1-62703-360-2_19  0.789
2013 Kalidasan K, Neo JL, Uttamchandani M. Direct visual detection of Salmonella genomic DNA using gold nanoparticles. Molecular Biosystems. 9: 618-21. PMID 23407714 DOI: 10.1039/C3Mb25527A  0.736
2012 Na Z, Li L, Uttamchandani M, Yao SQ. Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities. Chemical Communications (Cambridge, England). 48: 7304-6. PMID 22711056 DOI: 10.1039/C2Cc33476C  0.677
2012 Thangavelu K, Pan CQ, Karlberg T, Balaji G, Uttamchandani M, Suresh V, Schüler H, Low BC, Sivaraman J. Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Proceedings of the National Academy of Sciences of the United States of America. 109: 7705-10. PMID 22538822 DOI: 10.1073/Pnas.1116573109  0.352
2012 Gao L, Uttamchandani M, Yao SQ. Comparative proteomic profiling of mammalian cell lysates using phosphopeptide microarrays. Chemical Communications (Cambridge, England). 48: 2240-2. PMID 22252530 DOI: 10.1039/C2Cc17701C  0.794
2012 Foong YM, Fu J, Yao SQ, Uttamchandani M. Current advances in peptide and small molecule microarray technologies. Current Opinion in Chemical Biology. 16: 234-42. PMID 22221853 DOI: 10.1016/J.Cbpa.2011.12.007  0.818
2011 Shi H, Uttamchandani M, Yao SQ. Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates. Chemistry, An Asian Journal. 6: 2803-15. PMID 21898842 DOI: 10.1002/Asia.201100523  0.768
2011 Hu M, Li L, Wu H, Su Y, Yang PY, Uttamchandani M, Xu QH, Yao SQ. Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs). Journal of the American Chemical Society. 133: 12009-20. PMID 21732629 DOI: 10.1021/Ja200808Y  0.782
2011 Wu H, Ge J, Uttamchandani M, Yao SQ. Small molecule microarrays: the first decade and beyond. Chemical Communications (Cambridge, England). 47: 5664-70. PMID 21494728 DOI: 10.1039/C1Cc11464F  0.773
2011 Neo JL, Aw KD, Uttamchandani M. Visual SNP genotyping using asymmetric PCR and split DNA enzymes. The Analyst. 136: 1569-72. PMID 21384012 DOI: 10.1039/C0An00838A  0.311
2011 Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. A peptide aldehyde microarray for high-throughput profiling of cellular events. Journal of the American Chemical Society. 133: 1946-54. PMID 21247160 DOI: 10.1021/Ja109597V  0.811
2011 Uttamchandani M, Moochhala S. Microarray-based enzyme profiling: Recent advances and applications (Review). Biointerphases. 5: FA24-31. PMID 21171709 DOI: 10.1116/1.3462969  0.333
2011 Wu H, Ge J, Uttamchandani M, Yao SQ. ChemInform Abstract: Small Molecule Microarrays: The First Decade and Beyond Cheminform. 42: no-no. DOI: 10.1002/chin.201133267  0.622
2010 Aw KL, Yao SQ, Uttamchandani M. Nanodroplet microarrays for high-throughput enzyme screening. Methods in Molecular Biology (Clifton, N.J.). 669: 79-93. PMID 20857359 DOI: 10.1007/978-1-60761-845-4_7  0.65
2010 Shi H, Uttamchandani M, Yao SQ. A method for small molecule microarray-based screening for the rapid discovery of affinity-based probes. Methods in Molecular Biology (Clifton, N.J.). 669: 57-68. PMID 20857357 DOI: 10.1007/978-1-60761-845-4_5  0.755
2010 Uttamchandani M, Yao SQ. The expanding world of small molecule microarrays. Methods in Molecular Biology (Clifton, N.J.). 669: 1-15. PMID 20857353 DOI: 10.1007/978-1-60761-845-4_1  0.622
2010 Uttamchandani M. High-throughput screening of metalloproteases using small molecule microarrays. Methods in Molecular Biology (Clifton, N.J.). 632: 203-19. PMID 20217580 DOI: 10.1007/978-1-60761-663-4_13  0.448
2009 Uttamchandani M, Lu CH, Yao SQ. Next generation chemical proteomic tools for rapid enzyme profiling. Accounts of Chemical Research. 42: 1183-92. PMID 19435360 DOI: 10.1021/Ar9000586  0.794
2009 Uttamchandani M, Neo JL, Ong BN, Moochhala S. Applications of microarrays in pathogen detection and biodefence. Trends in Biotechnology. 27: 53-61. PMID 19008003 DOI: 10.1016/J.Tibtech.2008.09.004  0.318
2008 Uttamchandani M, Yao SQ. Peptide microarrays: next generation biochips for detection, diagnostics and high-throughput screening. Current Pharmaceutical Design. 14: 2428-38. PMID 18781992 DOI: 10.2174/138161208785777450  0.677
2008 Lu CH, Sun H, Abu Bakar FB, Uttamchandani M, Zhou W, Liou YC, Yao SQ. Rapid affinity-based fingerprinting of 14-3-3 isoforms using a combinatorial peptide microarray. Angewandte Chemie (International Ed. in English). 47: 7438-41. PMID 18698658 DOI: 10.1002/Anie.200801395  0.773
2008 Uttamchandani M, Li J, Sun H, Yao SQ. Activity-based protein profiling: new developments and directions in functional proteomics. Chembiochem : a European Journal of Chemical Biology. 9: 667-75. PMID 18283695 DOI: 10.1002/Cbic.200700755  0.788
2008 Sun H, Lu CH, Uttamchandani M, Xia Y, Liou YC, Yao SQ. Peptide microarray for high-throughput determination of phosphatase specificity and biology. Angewandte Chemie (International Ed. in English). 47: 1698-702. PMID 18203220 DOI: 10.1002/Anie.200703473  0.776
2007 Uttamchandani M, Lee WL, Wang J, Yao SQ. Quantitative inhibitor fingerprinting of metalloproteases using small molecule microarrays. Journal of the American Chemical Society. 129: 13110-7. PMID 17915867 DOI: 10.1021/Ja073914V  0.711
2007 Lee WL, Li J, Uttamchandani M, Sun H, Yao SQ. Inhibitor fingerprinting of metalloproteases using microplate and microarray platforms: an enabling technology in Catalomics. Nature Protocols. 2: 2126-38. PMID 17853868 DOI: 10.1038/Nprot.2007.305  0.783
2007 Uttamchandani M, Wang J, Li J, Hu M, Sun H, Chen KY, Liu K, Yao SQ. Inhibitor fingerprinting of matrix metalloproteases using a combinatorial peptide hydroxamate library. Journal of the American Chemical Society. 129: 7848-58. PMID 17539636 DOI: 10.1021/Ja070870H  0.808
2007 Uttamchandani M, Liu K, Panicker RC, Yao SQ. Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray. Chemical Communications (Cambridge, England). 1518-20. PMID 17406693 DOI: 10.1039/B702826A  0.829
2007 Wang J, Uttamchandani M, Sun H, Yao SQ. Small Molecule Microarrays: Applications Using Specially Tagged Chemical Libraries Cheminform. 38. DOI: 10.1002/chin.200705224  0.687
2006 Wang J, Uttamchandani M, Li J, Hu M, Yao SQ. "Click" synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases. Chemical Communications (Cambridge, England). 3783-5. PMID 16969456 DOI: 10.1039/B609446E  0.788
2006 Wang J, Uttamchandani M, Li J, Hu M, Yao SQ. Rapid assembly of matrix metalloprotease inhibitors using click chemistry. Organic Letters. 8: 3821-4. PMID 16898826 DOI: 10.1021/Ol061431A  0.787
2006 Uttamchandani M, Wang J, Yao SQ. Protein and small molecule microarrays: powerful tools for high-throughput proteomics. Molecular Biosystems. 2: 58-68. PMID 16880923 DOI: 10.1039/B513935J  0.708
2006 Hu Y, Uttamchandani M, Yao SQ. Microarray: a versatile platform for high-throughput functional proteomics. Combinatorial Chemistry & High Throughput Screening. 9: 203-12. PMID 16533154 DOI: 10.2174/138620706776055467  0.627
2006 Srinivasan R, Uttamchandani M, Yao SQ. Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases. Organic Letters. 8: 713-6. PMID 16468749 DOI: 10.1021/Ol052895W  0.789
2006 Wang J, Uttamchandani M, Sun LP, Yao SQ. Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays. Chemical Communications (Cambridge, England). 717-9. PMID 16465317 DOI: 10.1039/B515278J  0.697
2006 Wang J, Uttamchandani M, Sun H, Yao SQ. Small molecule microarrays: Applications using specially tagged chemical libraries Qsar and Combinatorial Science. 25: 1009-1019. DOI: 10.1002/Qsar.200640083  0.756
2005 Uttamchandani M, Huang X, Chen GY, Yao SQ. Nanodroplet profiling of enzymatic activities in a microarray. Bioorganic & Medicinal Chemistry Letters. 15: 2135-9. PMID 15808484 DOI: 10.1016/J.Bmcl.2005.02.019  0.624
2005 Uttamchandani M, Walsh DP, Yao SQ, Chang YT. Small molecule microarrays: recent advances and applications. Current Opinion in Chemical Biology. 9: 4-13. PMID 15701446 DOI: 10.1016/J.Cbpa.2004.12.005  0.678
2004 Uttamchandani M, Huang X, Chen GY, Tan LP, Yao SQ. Application of microarrays in high-throughput enzymatic profiling. Molecular Biotechnology. 28: 227-39. PMID 15542923 DOI: 10.1385/Mb:28:3:227  0.671
2004 Uttamchandani M, Walsh DP, Khersonsky SM, Huang X, Yao SQ, Chang YT. Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG. Journal of Combinatorial Chemistry. 6: 862-8. PMID 15530111 DOI: 10.1021/Cc049900S  0.649
2004 Uttamchandani M, Chen GY, Lesaicherre ML, Yao SQ. Site-specific peptide immobilization strategies for the rapid detection of kinase activity on microarrays. Methods in Molecular Biology (Clifton, N.J.). 264: 191-204. PMID 15020791 DOI: 10.1385/1-59259-759-9:191  0.664
2003 Yeo DS, Srinivasan R, Uttamchandani M, Chen GY, Zhu Q, Yao SQ. Cell-permeable small molecule probes for site-specific labeling of proteins. Chemical Communications (Cambridge, England). 2870-1. PMID 14680216 DOI: 10.1039/B309196A  0.799
2003 Uttamchandani M, Chan EW, Chen GY, Yao SQ. Combinatorial peptide microarrays for the rapid determination of kinase specificity. Bioorganic & Medicinal Chemistry Letters. 13: 2997-3000. PMID 12941320 DOI: 10.1016/S0960-894X(03)00633-4  0.748
2003 Zhu Q, Uttamchandani M, Li D, Lesaicherre ML, Yao SQ. Enzymatic profiling system in a small-molecule microarray. Organic Letters. 5: 1257-60. PMID 12688733 DOI: 10.1021/Ol034233H  0.716
2003 Chen GY, Uttamchandani M, Zhu Q, Wang G, Yao SQ. Developing a strategy for activity-based detection of enzymes in a protein microarray. Chembiochem : a European Journal of Chemical Biology. 4: 336-9. PMID 12672113 DOI: 10.1002/Cbic.200390054  0.695
2003 Zhu Q, Li DB, Uttamchandani M, Yao SQ. Facile synthesis of 7-amino-4-carbamoylmethylcoumarin (ACC)-containing solid supports and their corresponding fluorogenic protease substrates. Bioorganic & Medicinal Chemistry Letters. 13: 1033-6. PMID 12643905 DOI: 10.1016/S0960-894X(03)00087-8  0.63
2003 Chen GYJ, Uttamchandani M, Lue RYP, Lesaicherrea ML, Yao SQ. Array-based technologies and their applications in proteomics Current Topics in Medicinal Chemistry. 3: 705-724. PMID 12570860 DOI: 10.2174/1568026033452375  0.647
2002 Lesaicherre ML, Uttamchandani M, Chen GY, Yao SQ. Antibody-based fluorescence detection of kinase activity on a peptide array. Bioorganic & Medicinal Chemistry Letters. 12: 2085-8. PMID 12127509 DOI: 10.1016/S0960-894X(02)00378-5  0.654
2002 Lesaicherre ML, Uttamchandani M, Chen GY, Yao SQ. Developing site-specific immobilization strategies of peptides in a microarray. Bioorganic & Medicinal Chemistry Letters. 12: 2079-83. PMID 12127508 DOI: 10.1016/S0960-894X(02)00379-7  0.631
2002 Xie G, Uttamchandani M, Chen GY, Bu X, Lin SS, Wong KM, Yan W, Yao SQ, Guo Z. Substrate spectrum of tyrocidine thioesterase probed with randomized peptide N-acetylcysteamine thioesters. Bioorganic & Medicinal Chemistry Letters. 12: 989-92. PMID 11959010 DOI: 10.1016/S0960-894X(02)00067-7  0.6
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