| Year |
Citation |
Score |
| 2022 |
Wu X, Roberto JB, Knupp A, Greninger AL, Truong CD, Hollingshead N, Kenerson HL, Tuefferd M, Chen A, Koelle DM, Horton H, Jerome KR, Polyak SJ, Yeung RS, Crispe IN. Response of Human Liver Tissue to Innate Immune Stimuli. Frontiers in Immunology. 13: 811551. PMID 35355993 DOI: 10.3389/fimmu.2022.811551 |
0.44 |
|
| 2021 |
Polyak SJ, Crispe IN, Baumert TF. Liver Abnormalities after Elimination of HCV Infection: Persistent Epigenetic and Immunological Perturbations Post-Cure. Pathogens (Basel, Switzerland). 10. PMID 33430338 DOI: 10.3390/pathogens10010044 |
0.465 |
|
| 2020 |
Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, ... ... Polyak SJ, et al. Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma. Gut. PMID 32217639 DOI: 10.1136/Gutjnl-2019-318918 |
0.325 |
|
| 2019 |
Herod MR, Adeyemi OO, Ward J, Bentley K, Harris M, Stonehouse NJ, Polyak SJ. The broad-spectrum antiviral drug arbidol inhibits foot-and-mouth disease virus genome replication. The Journal of General Virology. PMID 31162013 DOI: 10.1099/Jgv.0.001283 |
0.339 |
|
| 2019 |
Hulseberg CE, Fénéant L, Szymańska-de Wijs KM, Kessler NP, Nelson EA, Shoemaker CJ, Schmaljohn CS, Polyak SJ, White JM. Arbidol and other Low Molecular Weight Drugs That Inhibit Lassa and Ebola Viruses. Journal of Virology. PMID 30700611 DOI: 10.1128/Jvi.02185-18 |
0.303 |
|
| 2018 |
Fink SL, Vojtech L, Wagoner J, Slivinski NSJ, Jackson KJ, Wang R, Khadka S, Luthra P, Basler CF, Polyak SJ. The Antiviral Drug Arbidol Inhibits Zika Virus. Scientific Reports. 8: 8989. PMID 29895962 DOI: 10.1038/S41598-018-27224-4 |
0.349 |
|
| 2017 |
Lovelace ES, Maurice NJ, Miller HW, Slichter CK, Harrington R, Magaret A, Prlic M, De Rosa S, Polyak SJ. Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells. Plos One. 12: e0171139. PMID 28158203 DOI: 10.1371/Journal.Pone.0171139 |
0.346 |
|
| 2016 |
Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ. The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. Journal of Virology. PMID 26739045 DOI: 10.1128/Jvi.02077-15 |
0.486 |
|
| 2015 |
Lovelace ES, Polyak SJ. Natural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic Infection. Viruses. 7: 6218-32. PMID 26633463 DOI: 10.3390/V7122933 |
0.52 |
|
| 2015 |
Lovelace ES, Wagoner J, MacDonald J, Bammler T, Bruckner J, Brownell J, Beyer RP, Zink EM, Kim YM, Kyle JE, Webb-Robertson BJ, Waters KM, Metz TO, Farin F, Oberlies NH, ... Polyak SJ, et al. Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling. Journal of Natural Products. 78: 1990-2000. PMID 26186142 DOI: 10.1021/acs.jnatprod.5b00288 |
0.734 |
|
| 2015 |
Al-Yahya S, Mahmoud L, Al-Zoghaibi F, Al-Tuhami A, Amer H, Almajhdi FN, Polyak SJ, Khabar KS. Human Cytokinome Analysis for Interferon Response. Journal of Virology. 89: 7108-19. PMID 25926649 DOI: 10.1128/Jvi.03729-14 |
0.418 |
|
| 2015 |
Pilkington LI, Wagoner J, Polyak SJ, Barker D. Enantioselective synthesis, stereochemical correction, and biological investigation of the rodgersinine family of 1,4-benzodioxane neolignans. Organic Letters. 17: 1046-9. PMID 25671292 DOI: 10.1021/Acs.Orglett.5B00189 |
0.347 |
|
| 2014 |
Stone AE, Mitchell A, Brownell J, Miklin DJ, Golden-Mason L, Polyak SJ, Gale MJ, Rosen HR. Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression. Plos One. 9: e95627. PMID 24788809 DOI: 10.1371/Journal.Pone.0095627 |
0.794 |
|
| 2014 |
Blaising J, Polyak SJ, Pécheur EI. Arbidol as a broad-spectrum antiviral: an update. Antiviral Research. 107: 84-94. PMID 24769245 DOI: 10.1016/J.Antiviral.2014.04.006 |
0.412 |
|
| 2014 |
McClure J, Margineantu DH, Sweet IR, Polyak SJ. Inhibition of HIV by Legalon-SIL is independent of its effect on cellular metabolism. Virology. 449: 96-103. PMID 24418542 DOI: 10.1016/J.Virol.2013.11.003 |
0.305 |
|
| 2014 |
Brownell J, Bruckner J, Wagoner J, Thomas E, Loo YM, Gale M, Liang TJ, Polyak SJ. Direct, interferon-independent activation of the CXCL10 promoter by NF-κB and interferon regulatory factor 3 during hepatitis C virus infection. Journal of Virology. 88: 1582-90. PMID 24257594 DOI: 10.1128/Jvi.02007-13 |
0.805 |
|
| 2013 |
Blaising J, Lévy PL, Polyak SJ, Stanifer M, Boulant S, Pécheur EI. Arbidol inhibits viral entry by interfering with clathrin-dependent trafficking. Antiviral Research. 100: 215-9. PMID 23981392 DOI: 10.1016/J.Antiviral.2013.08.008 |
0.398 |
|
| 2013 |
Brownell J, Wagoner J, Lovelace ES, Thirstrup D, Mohar I, Smith W, Giugliano S, Li K, Crispe IN, Rosen HR, Polyak SJ. Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes. Journal of Hepatology. 59: 701-8. PMID 23770038 DOI: 10.1016/J.Jhep.2013.06.001 |
0.801 |
|
| 2013 |
Polyak SJ. The circulatory orbit of micro-RNAs in hepatitis C. Hepatology (Baltimore, Md.). 58: 847-9. PMID 23712324 DOI: 10.1002/Hep.26508 |
0.362 |
|
| 2013 |
Blaising J, Lévy PL, Gondeau C, Phelip C, Varbanov M, Teissier E, Ruggiero F, Polyak SJ, Oberlies NH, Ivanovic T, Boulant S, Pécheur EI. Silibinin inhibits hepatitis C virus entry into hepatocytes by hindering clathrin-dependent trafficking. Cellular Microbiology. 15: 1866-82. PMID 23701235 DOI: 10.1111/Cmi.12155 |
0.604 |
|
| 2013 |
Althagafy HS, Graf TN, Sy-Cordero AA, Gufford BT, Paine MF, Wagoner J, Polyak SJ, Croatt MP, Oberlies NH. Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle. Bioorganic & Medicinal Chemistry. 21: 3919-26. PMID 23673225 DOI: 10.1016/J.Bmc.2013.04.017 |
0.387 |
|
| 2013 |
Brownell J, Polyak SJ. Molecular pathways: hepatitis C virus, CXCL10, and the inflammatory road to liver cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1347-52. PMID 23322900 DOI: 10.1158/1078-0432.Ccr-12-0928 |
0.796 |
|
| 2013 |
Esser-Nobis K, Romero-Brey I, Ganten TM, Gouttenoire J, Harak C, Klein R, Schemmer P, Binder M, Schnitzler P, Moradpour D, Bartenschlager R, Polyak SJ, Stremmel W, Penin F, Eisenbach C, et al. Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B. Hepatology (Baltimore, Md.). 57: 953-63. PMID 23322644 DOI: 10.1002/Hep.26260 |
0.542 |
|
| 2013 |
Sy-Cordero AA, Graf TN, Runyon SP, Wani MC, Kroll DJ, Agarwal R, Brantley SJ, Paine MF, Polyak SJ, Oberlies NH. Enhanced bioactivity of silybin B methylation products. Bioorganic & Medicinal Chemistry. 21: 742-7. PMID 23260576 DOI: 10.1016/J.Bmc.2012.11.035 |
0.331 |
|
| 2013 |
Polyak SJ, Ferenci P, Pawlotsky JM. Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection. Hepatology (Baltimore, Md.). 57: 1262-71. PMID 23213025 DOI: 10.1002/Hep.26179 |
0.513 |
|
| 2013 |
Polyak SJ, Oberlies NH, Pécheur EI, Dahari H, Ferenci P, Pawlotsky JM. Silymarin for HCV infection. Antiviral Therapy. 18: 141-7. PMID 23011959 DOI: 10.3851/Imp2402 |
0.516 |
|
| 2012 |
Smith WE, Brownell J, White CC, Afsharinejad Z, Tsai J, Hu X, Polyak SJ, Gao X, Kavanagh TJ, Eaton DL. In vitro toxicity assessment of amphiphillic polymer-coated CdSe/ZnS quantum dots in two human liver cell models. Acs Nano. 6: 9475-84. PMID 23039050 DOI: 10.1021/Nn302288R |
0.731 |
|
| 2012 |
McClure J, Lovelace ES, Elahi S, Maurice NJ, Wagoner J, Dragavon J, Mittler JE, Kraft Z, Stamatatos L, Stamatatos L, Horton H, De Rosa SC, Coombs RW, Polyak SJ. Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation. Plos One. 7: e41832. PMID 22848626 DOI: 10.1371/Journal.Pone.0041832 |
0.429 |
|
| 2012 |
Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo ES, Higgs MR, Loo YM, Golden-Mason L, Lindenbach BD, Baumert TF, Randall G, Gale M. A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology. 142: e1-5. PMID 22185796 DOI: 10.1053/J.Gastro.2011.11.002 |
0.402 |
|
| 2012 |
Tacke RS, Lee HC, Goh C, Courtney J, Polyak SJ, Rosen HR, Hahn YS. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology (Baltimore, Md.). 55: 343-53. PMID 21953144 DOI: 10.1002/Hep.24700 |
0.575 |
|
| 2012 |
Brownell J, Wagoner J, Thirstrup D, Smith W, Li K, Polyak S. O031 TLR3 and RIG-I sensing of HCV infection by hepatocytes leads to interferon-independent CXCL10 induction Cytokine. 59: 511-512. DOI: 10.1016/j.cyto.2012.06.065 |
0.794 |
|
| 2011 |
Goldwasser J, Cohen PY, Lin W, Kitsberg D, Balaguer P, Polyak SJ, Chung RT, Yarmush ML, Nahmias Y. Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. Journal of Hepatology. 55: 963-71. PMID 21354229 DOI: 10.1016/J.Jhep.2011.02.011 |
0.601 |
|
| 2011 |
Wagoner J, Morishima C, Graf TN, Oberlies NH, Teissier E, Pécheur EI, Tavis JE, Polyak SJ. Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation. Plos One. 6: e16464. PMID 21297992 DOI: 10.1371/Journal.Pone.0016464 |
0.559 |
|
| 2010 |
Wagoner J, Negash A, Kane OJ, Martinez LE, Nahmias Y, Bourne N, Owen DM, Grove J, Brimacombe C, McKeating JA, Pécheur EI, Graf TN, Oberlies NH, Lohmann V, Cao F, ... ... Polyak SJ, et al. Multiple effects of silymarin on the hepatitis C virus lifecycle. Hepatology (Baltimore, Md.). 51: 1912-21. PMID 20512985 DOI: 10.1002/Hep.23587 |
0.545 |
|
| 2010 |
Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, Liu Y, Graf TN, Oberlies NH. Identification of hepatoprotective flavonolignans from silymarin. Proceedings of the National Academy of Sciences of the United States of America. 107: 5995-9. PMID 20231449 DOI: 10.1073/Pnas.0914009107 |
0.489 |
|
| 2010 |
Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, Randall JA, McMahan R, Zimmerman MA, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ, Hirashima M, Rosen HR. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. Plos One. 5: e9504. PMID 20209097 DOI: 10.1371/Journal.Pone.0009504 |
0.589 |
|
| 2010 |
Tang X, Wagoner J, Negash A, Austin M, McLauchlan J, Hahn YS, Rosen HR, Polyak SJ. Functional characterization of core genes from patients with acute hepatitis C virus infection. The Journal of Infectious Diseases. 201: 912-22. PMID 20170366 DOI: 10.1086/650699 |
0.579 |
|
| 2010 |
Pal S, Polyak SJ, Bano N, Qiu WC, Carithers RL, Shuhart M, Gretch DR, Das A. Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1. Journal of Gastroenterology and Hepatology. 25: 627-34. PMID 20074151 DOI: 10.1111/J.1440-1746.2009.06128.X |
0.479 |
|
| 2010 |
Pawlotsky JM, Cocquerel L, Durantel D, Lavillette D, Lerat H, Pécheur EI, Polyak SJ, Tautz N, Thimme R. HCV research 20 years after discovery: a summary of the 16th international symposium on hepatitis C virus and related viruses. Gastroenterology. 138: 6-12.e1-2. PMID 19931267 DOI: 10.1053/J.Gastro.2009.11.018 |
0.532 |
|
| 2010 |
Morishima C, Shuhart MC, Wang CC, Paschal DM, Apodaca MC, Liu Y, Sloan DD, Graf TN, Oberlies NH, Lee DY, Jerome KR, Polyak SJ. Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection. Gastroenterology. 138: 671-81, 681.e1-2. PMID 19782083 DOI: 10.1053/J.Gastro.2009.09.021 |
0.531 |
|
| 2010 |
Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, Randall JA, McMahan R, Zimmerman MA, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ, Hirashima M, Rosen HR. Correction: A Crucial Role for Kupffer Cell-Derived Galectin-9 in Regulation of T Cell Immunity in Hepatitis C Infection Plos One. 5. DOI: 10.1371/annotation/d15b793c-85c7-4529-bc80-aabcb088a8cf |
0.324 |
|
| 2008 |
Polyak SJ, Morishima C, Hawke R. Antiviral effects of silymarin against hepatitis C: the jury is still out. Hepatology (Baltimore, Md.). 48: 345-6. PMID 18509876 DOI: 10.1002/Hep.22235 |
0.455 |
|
| 2008 |
Boriskin YS, Leneva IA, Pécheur EI, Polyak SJ. Arbidol: a broad-spectrum antiviral compound that blocks viral fusion. Current Medicinal Chemistry. 15: 997-1005. PMID 18393857 DOI: 10.2174/092986708784049658 |
0.457 |
|
| 2008 |
Chung RT, Gale M, Polyak SJ, Lemon SM, Liang TJ, Hoofnagle JH. Mechanisms of action of interferon and ribavirin in chronic hepatitis C: Summary of a workshop. Hepatology (Baltimore, Md.). 47: 306-20. PMID 18161743 DOI: 10.1002/Hep.22070 |
0.6 |
|
| 2008 |
Polyak SJ. Resistance of HBV and HCV to antiviral therapies Future Virology. 3: 221-224. DOI: 10.2217/17460794.3.3.221 |
0.514 |
|
| 2007 |
Wertheimer AM, Polyak SJ, Leistikow R, Rosen HR. Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells. Hepatology (Baltimore, Md.). 45: 1422-32. PMID 17538964 DOI: 10.1002/Hep.21637 |
0.563 |
|
| 2007 |
Polyak SJ, Morishima C, Shuhart MC, Wang CC, Liu Y, Lee DY. Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin. Gastroenterology. 132: 1925-36. PMID 17484885 DOI: 10.1053/J.Gastro.2007.02.038 |
0.58 |
|
| 2007 |
Pécheur EI, Lavillette D, Alcaras F, Molle J, Boriskin YS, Roberts M, Cosset FL, Polyak SJ. Biochemical mechanism of hepatitis C virus inhibition by the broad-spectrum antiviral arbidol. Biochemistry. 46: 6050-9. PMID 17455911 DOI: 10.1021/Bi700181J |
0.567 |
|
| 2007 |
Wagoner J, Austin M, Green J, Imaizumi T, Casola A, Brasier A, Khabar KS, Wakita T, Gale M, Polyak SJ. Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. Journal of Virology. 81: 309-18. PMID 17035306 DOI: 10.1128/Jvi.01411-06 |
0.53 |
|
| 2006 |
Koo BC, McPoland P, Wagoner JP, Kane OJ, Lohmann V, Polyak SJ. Relationships between hepatitis C virus replication and CXCL-8 production in vitro. Journal of Virology. 80: 7885-93. PMID 16873245 DOI: 10.1128/Jvi.00519-06 |
0.58 |
|
| 2006 |
Boriskin YS, Pécheur EI, Polyak SJ. Arbidol: a broad-spectrum antiviral that inhibits acute and chronic HCV infection. Virology Journal. 3: 56. PMID 16854226 DOI: 10.1186/1743-422X-3-56 |
0.588 |
|
| 2006 |
Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity. Alcoholism, Clinical and Experimental Research. 30: 709-19. PMID 16573590 DOI: 10.1111/J.1530-0277.2006.00083.X |
0.497 |
|
| 2006 |
Morishima C, Polyak SJ, Ray R, Doherty MC, Di Bisceglie AM, Malet PF, Bonkovsky HL, Sullivan DG, Gretch DR, Rothman AL, Koziel MJ, Lindsay KL. Hepatitis C virus-specific immune responses and quasi-species variability at baseline are associated with nonresponse to antiviral therapy during advanced hepatitis C. The Journal of Infectious Diseases. 193: 931-40. PMID 16518754 DOI: 10.1086/500952 |
0.581 |
|
| 2006 |
Green J, Khabar KS, Koo BC, Williams BR, Polyak SJ. Stability of CXCL-8 and related AU-rich mRNAs in the context of hepatitis C virus replication in vitro. The Journal of Infectious Diseases. 193: 802-11. PMID 16479515 DOI: 10.1086/500510 |
0.57 |
|
| 2006 |
Polyak SJ. Resistance of hepatitis C virus to the host antiviral response Future Virology. 1: 89-98. DOI: 10.2217/17460794.1.1.89 |
0.557 |
|
| 2005 |
Plumlee CR, Lazaro CA, Fausto N, Polyak SJ. Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. Virology Journal. 2: 89. PMID 16324217 DOI: 10.1186/1743-422X-2-89 |
0.538 |
|
| 2005 |
Polyak SJ, Sullivan DG, Austin MA, Dai JY, Shuhart MC, Lindsay KL, Bonkovsky HL, Di Bisceglie AM, Lee WM, Morishima C, Gretch DR. Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis. Virology Journal. 2: 41. PMID 15847697 DOI: 10.1186/1743-422X-2-41 |
0.505 |
|
| 2005 |
Rothman AL, Morishima C, Bonkovsky HL, Polyak SJ, Ray R, Di Bisceglie AM, Lindsay KL, Malet PF, Chang M, Gretch DR, Sullivan DG, Bhan AK, Wright EC, Koziel MJ. Associations among clinical, immunological, and viral quasispecies measurements in advanced chronic hepatitis C. Hepatology (Baltimore, Md.). 41: 617-25. PMID 15726656 DOI: 10.1002/Hep.20581 |
0.585 |
|
| 2004 |
Khabar KS, Al-Haj L, Al-Zoghaibi F, Marie M, Dhalla M, Polyak SJ, Williams BR. Expressed gene clusters associated with cellular sensitivity and resistance towards anti-viral and anti-proliferative actions of interferon. Journal of Molecular Biology. 342: 833-46. PMID 15342240 DOI: 10.1016/J.Jmb.2004.07.065 |
0.396 |
|
| 2004 |
Klein KC, Polyak SJ, Lingappa JR. Unique features of hepatitis C virus capsid formation revealed by de novo cell-free assembly. Journal of Virology. 78: 9257-69. PMID 15308720 DOI: 10.1128/Jvi.78.17.9257-9269.2004 |
0.562 |
|
| 2004 |
Miller K, McArdle S, Gale MJ, Geller DA, Tenoever B, Hiscott J, Gretch DR, Polyak SJ. Effects of the hepatitis C virus core protein on innate cellular defense pathways. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 24: 391-402. PMID 15296650 DOI: 10.1089/1079990041535647 |
0.55 |
|
| 2003 |
Wang C, Polyak SJ, Corey L. Detection of hepatitis C virus RNA in normal cervical smears. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 314; author reply 31. PMID 12856226 DOI: 10.1086/375847 |
0.376 |
|
| 2003 |
Polyak SJ. Hepatitis C virus--cell interactions and their role in pathogenesis. Clinics in Liver Disease. 7: 67-88. PMID 12691459 DOI: 10.1016/S1089-3261(02)00075-2 |
0.578 |
|
| 2003 |
MORISHIMA C, RAY R, POLYAK S, SULLIVAN D, DIBISCEGLIE A, LEE W, BONKOVSKY H, GRETCH D, WRIGHT E, ROTHMAN A. 221 HCV-specific immune responses at baseline do not predict virologic response to antiviral therapy in advanced hepatitis C Hepatology. 38: 263-263. DOI: 10.1016/S0270-9139(03)80264-1 |
0.526 |
|
| 2002 |
Khabar KS, Polyak SJ. Hepatitis C virus-host interactions: the NS5A protein and the interferon/chemokine systems. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 1005-12. PMID 12433279 DOI: 10.1089/107999002760624224 |
0.561 |
|
| 2002 |
He Y, Nakao H, Tan SL, Polyak SJ, Neddermann P, Vijaysri S, Jacobs BL, Katze MG. Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. Journal of Virology. 76: 9207-17. PMID 12186904 DOI: 10.1128/Jvi.76.18.9207-9217.2002 |
0.447 |
|
| 2002 |
Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM. Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. Virology. 292: 198-210. PMID 11878923 DOI: 10.1006/Viro.2001.1225 |
0.486 |
|
| 2002 |
Nolte FS, Fried MW, Shiffman ML, Ferreira-Gonzalez A, Garrett CT, Schiff ER, Polyak SJ, Gretch DR. Prospective multicenter clinical evaluation of AMPLICOR and COBAS AMPLICOR hepatitis C virus tests. Journal of Clinical Microbiology. 39: 4005-12. PMID 11682522 DOI: 10.1128/JCM.39.11.4005-4012.2001 |
0.338 |
|
| 2001 |
Polyak SJ, Khabar KS, Rezeiq M, Gretch DR. Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. Journal of Virology. 75: 6209-11. PMID 11390624 DOI: 10.1128/Jvi.75.13.6209-6211.2001 |
0.576 |
|
| 2001 |
Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR. Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. Journal of Virology. 75: 6095-106. PMID 11390611 DOI: 10.1128/Jvi.75.13.6095-6106.2001 |
0.544 |
|
| 2001 |
Ezelle HJ, Balachandran S, Sicheri F, Polyak SJ, Barber GN. Analyzing the mechanisms of interferon-induced apoptosis using CrmA and hepatitis C virus NS5A Virology. 281: 124-137. PMID 11222103 DOI: 10.1006/Viro.2001.0815 |
0.463 |
|
| 2000 |
Nousbaum J, Polyak SJ, Ray SC, Sullivan DG, Larson AM, Carithers RL, Gretch DR. Prospective characterization of full-length hepatitis C virus NS5A quasispecies during induction and combination antiviral therapy. Journal of Virology. 74: 9028-38. PMID 10982347 DOI: 10.1128/Jvi.74.19.9028-9038.2000 |
0.549 |
|
| 2000 |
Polyak SJ, Nousbaum JB, Larson AM, Cotler S, Carithers RL, Gretch DR. The protein kinase-interacting domain in the hepatitis C virus envelope glycoprotein-2 gene is highly conserved in genotype 1-infected patients treated with interferon. The Journal of Infectious Diseases. 182: 397-404. PMID 10915068 DOI: 10.1086/315720 |
0.56 |
|
| 1999 |
Gerotto M, Dal Pero F, Sullivan DG, Chemello L, Cavalletto L, Polyak SJ, Pontisso P, Gretch DR, Alberti A. Evidence for sequence selection within the non-structural 5A gene of hepatitis C virus type 1b during unsuccessful treatment with interferon-alpha. Journal of Viral Hepatitis. 6: 367-72. PMID 10607252 DOI: 10.1046/J.1365-2893.1999.00166.X |
0.505 |
|
| 1999 |
Gerotto M, Sullivan DG, Polyak SJ, Chemello L, Cavalletto L, Pontisso P, Alberti A, Gretch DR. Effect of retreatment with interferon alone or interferon plus ribavirin on hepatitis C virus quasispecies diversification in nonresponder patients with chronic hepatitis C. Journal of Virology. 73: 7241-7. PMID 10438811 DOI: 10.1128/Jvi.73.9.7241-7247.1999 |
0.533 |
|
| 1999 |
Polyak SJ, Paschal DM, McArdle S, Michael J, Moradpour D, Gretch DR. Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication. Hepatology. 29: 1262-1271. PMID 10094974 DOI: 10.1002/Hep.510290438 |
0.514 |
|
| 1999 |
Polyak SJ. Interfering with interferon Trends in Microbiology. 7: 401. DOI: 10.1016/S0966-842X(99)01592-9 |
0.377 |
|
| 1998 |
Gale M, Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, Polyak SJ, Gretch DR, Katze MG. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation Molecular and Cellular Biology. 18: 5208-5218. PMID 9710605 DOI: 10.1128/Mcb.18.9.5208 |
0.559 |
|
| 1998 |
Polyak SJ, McArdle S, Liu SL, Sullivan DG, Chung M, Hofgärtner WT, Carithers RL, McMahon BJ, Mullins JI, Corey L, Gretch DR. Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection. Journal of Virology. 72: 4288-96. PMID 9557719 DOI: 10.1128/Jvi.72.5.4288-4296.1998 |
0.5 |
|
| 1998 |
Polyak SJ, McArdle S, Liu S, Sullivan DG, Chung M, Hofgärtner WT, Carithers RL, McMahon BJ, Mullins JI, Corey L, Gretch DR. Evolution of Hepatitis C Virus Quasispecies in Hypervariable Region 1 and the Putative Interferon Sensitivity-Determining Region during Interferon Therapy and Natural Infection Journal of Virology. 72: 4288-4296. DOI: 10.1128/jvi.72.5.4288-4296.1998 |
0.405 |
|
| 1997 |
Hofgärtner WT, Polyak SJ, Sullivan DG, Carithers RL, Gretch DR. Mutations in the NS5A gene of hepatitis C virus in North American patients infected with HCV genotype 1a or 1b. Journal of Medical Virology. 53: 118-26. PMID 9334922 DOI: 10.1002/(Sici)1096-9071(199710)53:2<118::Aid-Jmv3>3.0.Co;2-C |
0.529 |
|
| 1997 |
Gale MJ, Korth MJ, Tang NM, Tan SL, Hopkins DA, Dever TE, Polyak SJ, Gretch DR, Katze MG. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein Virology. 230: 217-227. PMID 9143277 DOI: 10.1006/Viro.1997.8493 |
0.594 |
|
| 1997 |
Polyak SJ, Faulkner G, Carithers RL, Corey L, Gretch DR. Assessment of hepatitis C virus quasispecies heterogeneity by gel shift analysis: correlation with response to interferon therapy. The Journal of Infectious Diseases. 175: 1101-7. PMID 9129072 DOI: 10.1086/516448 |
0.487 |
|
| 1997 |
Wilson JJ, Polyak SJ, Day TD, Gretch DR. Characterization of simple and complex hepatitis C virus quasispecies by heteroduplex gel shift analysis: correlation with nucleotide sequencing. The Journal of General Virology. 1763-71. PMID 9049381 DOI: 10.1099/0022-1317-76-7-1763 |
0.502 |
|
| 1996 |
Gretch DR, Polyak SJ, Wilson JJ, Carithers RL, Perkins JD, Corey L. Tracking hepatitis C virus quasispecies major and minor variants in symptomatic and asymptomatic liver transplant recipients. Journal of Virology. 70: 7622-31. PMID 8892882 DOI: 10.1128/Jvi.70.11.7622-7631.1996 |
0.539 |
|
| 1996 |
Gretch DR, Polyak SJ, Willson RA, Carithers RL. Treatment of chronic hepatitis C virus infection: a clinical and virological perspective. Advances in Experimental Medicine and Biology. 394: 207-24. PMID 8815687 DOI: 10.1007/978-1-4757-9209-6_20 |
0.564 |
|
| 1996 |
Lieber A, He CY, Polyak SJ, Gretch DR, Barr D, Kay MA. Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes. Journal of Virology. 70: 8782-8791. DOI: 10.1128/Jvi.70.12.8782-8791.1996 |
0.571 |
|
| 1991 |
Polyak SJ, Rawls WE, Harnish DG. Characterization of Pichinde virus infection of cells of the monocytic lineage. Journal of Virology. 65: 3575-82. PMID 2041083 DOI: 10.1128/Jvi.65.7.3575-3582.1991 |
0.306 |
|
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