Jeremy W. Prokop, Ph.D. - Publications

Affiliations: 
2008-2013 Intregrated Bioscience University of Akron, Akron, OH, United States 
 2013-2015 HMGC Medical College of Wisconsin, Milwaukee, WI, United States 
 2015- HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States 
Area:
Molecular Biology, Genetics

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Underwood A, Rasicci DT, Hinds D, Mitchell JT, Zieba JK, Mills J, Arnold NE, Cook TW, Moustaqil M, Gambin Y, Sierecki E, Fontaine F, Vanderweele S, Das AS, Cvammen W, ... ... Prokop JW, et al. Evolutionary Landscape of Genes to Inform Genotype-to-Phenotype Relationships. Genes. 14. PMID 36672963 DOI: 10.3390/genes14010222  0.625
2020 Fan F, Geurts AM, Pabbidi MR, Ge Y, Zhang C, Wang S, Liu Y, Gao W, Guo Y, Li L, He X, Lv W, Muroya Y, Hirata T, Prokop J, et al. A Mutation in -Adducin Impairs Autoregulation of Renal Blood Flow and Promotes the Development of Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 32029431 DOI: 10.1681/Asn.2019080784  0.458
2019 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, ... ... Prokop JW, et al. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature Genetics. PMID 31406347 DOI: 10.1038/S41588-019-0475-Y  0.319
2018 Snijders Blok L, Hiatt SM, Bowling KM, Prokop JW, Engel KL, Cochran JN, Bebin EM, Bijlsma EK, Ruivenkamp CAL, Terhal P, Simon MEH, Smith R, Hurst JA, McLaughlin H, et al. De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder. Human Genetics. PMID 29740699 DOI: 10.1007/S00439-018-1887-Y  0.347
2018 Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy LG, Meijer FA, Geurts AM, et al. Characterization of Coding/Noncoding Variants forin Patients with CKD. Journal of the American Society of Nephrology : Jasn. PMID 29476007 DOI: 10.1681/Asn.2017080856  0.502
2017 Peng H, Prokop J, Karar J, Park K, Cao L, Harbour JW, Bowcock AM, Malkowicz SB, Cheung M, Testa JR, Rauscher FJ. Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains. Cancer Research. PMID 29284740 DOI: 10.1158/0008-5472.Can-17-2876  0.318
2017 Londraville RL, Prokop JW, Duff RJ, Liu Q, Tuttle M. On the Molecular Evolution of Leptin, Leptin Receptor, and Endospanin. Frontiers in Endocrinology. 8: 58. PMID 28443063 DOI: 10.3389/Fendo.2017.00058  0.409
2017 Prokop JW, Lazar J, Crapitto G, Smith DC, Worthey EA, Jacob HJ. Molecular modeling in the age of clinical genomics, the enterprise of the next generation. Journal of Molecular Modeling. 23: 75. PMID 28204942 DOI: 10.1007/S00894-017-3258-3  0.552
2017 Cramer JM, Pohlmann D, Gomez F, Mark L, Kornegay B, Hall C, Siraliev-Perez E, Walavalkar NM, Sperlazza MJ, Bilinovich S, Prokop JW, Hill AL, Williams DC. Methylation specific targeting of a chromatin remodeling complex from sponges to humans. Scientific Reports. 7: 40674. PMID 28094816 DOI: 10.1038/Srep40674  0.315
2017 Prokop JW, Smith C, Bilinovich SM, Williams DC, Jacob HJ. Transcription Factor-DNA Interaction: From Encode to Biophysics using Evolution and Molecular Dynamic Simulations Biophysical Journal. 112: 292a. DOI: 10.1016/J.Bpj.2016.11.1581  0.573
2016 Wilson JM, Prokop JW, Lorimer E, Ntantie E, Williams CL. Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B. Journal of Molecular Biology. PMID 27760305 DOI: 10.1016/J.Jmb.2016.10.016  0.331
2016 Ball HC, Londraville RL, Prokop JW, George JC, Suydam RS, Vinyard C, Thewissen JG, Duff RJ. Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. PMID 27573204 DOI: 10.1007/S00360-016-1029-6  0.312
2016 Prokop JW, Tsaih SW, Faber AB, Boehme S, Underwood AC, Troyer S, Playl L, Milsted A, Turner ME, Ely D, Martins AS, Tutaj M, Lazar J, Dwinell MR, Jacob HJ. The phenotypic impact of the male-specific region of chromosome-Y in inbred mating: the role of genetic variants and gene duplications in multiple inbred rat strains. Biology of Sex Differences. 7: 10. PMID 26848384 DOI: 10.1186/S13293-016-0064-Z  0.688
2016 Bergom C, Hauser AD, Rymaszewski A, Gonyo P, Prokop JW, Jennings BC, Lawton AJ, Frei A, Lorimer EL, Aguilera-Barrantes I, Mackinnon AC, Noon K, Fierke CA, Williams CL. The Tumor Suppressive Small GTPase DiRas1 Binds the Non-canonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases. The Journal of Biological Chemistry. PMID 26814130 DOI: 10.1074/Jbc.M115.696831  0.304
2015 Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A. 2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. Journal of Cardiovascular Translational Research. 8: 269-77. PMID 25920443 DOI: 10.1007/S12265-015-9626-4  0.302
2015 Rudemiller NP, Lund H, Priestley JR, Endres BT, Prokop JW, Jacob HJ, Geurts AM, Cohen EP, Mattson DL. Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. Hypertension. 65: 1111-7. PMID 25776069 DOI: 10.1161/Hypertensionaha.114.04736  0.539
2015 Chang AT, Liu Y, Ayyanathan K, Benner C, Jiang Y, Prokop JW, Paz H, Wang D, Li HR, Fu XD, Rauscher FJ, Yang J. An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors. Genes & Development. 29: 603-16. PMID 25762439 DOI: 10.1101/Gad.242842.114  0.354
2015 Araujo FC, Milsted A, Watanabe IK, Del Puerto HL, Santos RA, Lazar J, Reis FM, Prokop JW. Similarities and differences of X and Y chromosome homologous genes, SRY and SOX3, in regulating the renin-angiotensin system promoters. Physiological Genomics. 47: 177-86. PMID 25759379 DOI: 10.1152/Physiolgenomics.00138.2014  0.661
2015 Prokop JW, Petri V, Shimoyama ME, Watanabe IK, Casarini DE, Leeper TC, Bilinovich SM, Jacob HJ, Santos RA, Martins AS, Araujo FC, Reis FM, Milsted A. Structural libraries of protein models for multiple species to understand evolution of the renin-angiotensin system. General and Comparative Endocrinology. 215: 106-16. PMID 25260253 DOI: 10.1016/J.Ygcen.2014.09.010  0.704
2015 Prokop JW, Deschepper CF. Chromosome Y genetic variants: Impact in animal models and on human disease Physiological Genomics. 47: 525-537. DOI: 10.1152/Physiolgenomics.00074.2015  0.399
2014 Prisco SZ, Prokop JW, Sarkis AB, Yeo NC, Hoffman MJ, Hansen CC, Jacob HJ, Flister MJ, Lazar J. Refined mapping of a hypertension susceptibility locus on rat chromosome 12. Hypertension. 64: 883-90. PMID 25001272 DOI: 10.1161/Hypertensionaha.114.03550  0.52
2014 Dores RM, Londraville RL, Prokop J, Davis P, Dewey N, Lesinski N. Molecular evolution of GPCRs: Melanocortin/melanocortin receptors. Journal of Molecular Endocrinology. 52: T29-42. PMID 24868105 DOI: 10.1530/Jme-14-0050  0.312
2014 Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays HL, Cogburn LA, Londraville RL. Discovery of the elusive leptin in birds: identification of several 'missing links' in the evolution of leptin and its receptor. Plos One. 9: e92751. PMID 24663438 DOI: 10.1371/Journal.Pone.0092751  0.663
2014 Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, et al. LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase. Cancer Research. 74: 1390-403. PMID 24590809 DOI: 10.1158/0008-5472.Can-13-1275  0.31
2014 Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC. The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region. Journal of Molecular Biology. 426: 1753-65. PMID 24486611 DOI: 10.1016/J.Jmb.2014.01.007  0.349
2014 Prokop JW, Rauscher FJ, Peng H, Liu Y, Araujo FC, Watanabe I, Reis FM, Milsted A. MAS promoter regulation: a role for Sry and tyrosine nitration of the KRAB domain of ZNF274 as a feedback mechanism. Clinical Science (London, England : 1979). 126: 727-38. PMID 24128372 DOI: 10.1042/Cs20130385  0.668
2014 Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays HL, Cogburn LA, Londraville RL. Purification of Peregrine falcon lepin (pfleptin). Plos One. DOI: 10.1371/Journal.Pone.0092751.G005  0.579
2014 Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays HL, Cogburn LA, Londraville RL. Avian leptin bound to leptin receptor. Plos One. DOI: 10.1371/Journal.Pone.0092751.G004  0.594
2014 Prokop JW, Schmidt C, Gasper D, Duff RJ, Milsted A, Ohkubo T, Ball HC, Shawkey MD, Mays HL, Cogburn LA, Londraville RL. Bird Leptin gene and protein product compared to other vertebrate species. Plos One. DOI: 10.1371/Journal.Pone.0092751.G001  0.628
2014 Peng H, Farrooji MTZ, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, et al. Abstract 992: LIMD2 is a small LIM-only protein overexpressed in metastatic lesions which regulates cell motility and tumor progression by directly binding to and activating the integrin-linked-kinase Cancer Research. 74: 992-992. DOI: 10.1158/1538-7445.Am2014-992  0.313
2014 Liu Y, Prokop JW, Peng H, Rauscher FJ. Abstract 1061: High resolution DNA recognition by the Snail zinc finger protein: Testing of a molecular dynamics based model defines the atomic level interactions required for high affinity binding, E-box specificity and reveals potential strategies for small molecule control of EMT transcriptional programs Cancer Research. 74: 1061-1061. DOI: 10.1158/1538-7445.Am2014-1061  0.35
2013 Prokop JW, Underwood AC, Turner ME, Miller N, Pietrzak D, Scott S, Smith C, Milsted A. Analysis of Sry duplications on the Rattus norvegicus Y-chromosome. Bmc Genomics. 14: 792. PMID 24228692 DOI: 10.1186/1471-2164-14-792  0.647
2013 Prokop JW, Santos RA, Milsted A. Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: using in silico techniques to differentiate the three receptors. Plos One. 8: e65307. PMID 23755216 DOI: 10.1371/Journal.Pone.0065307  0.638
2013 Prokop JW, Liu Y, Milsted A, Peng H, Rauscher FJ. A method for in silico identification of SNAIL/SLUG DNA binding potentials to the E-box sequence using molecular dynamics and evolutionary conserved amino acids. Journal of Molecular Modeling. 19: 3463-9. PMID 23708613 DOI: 10.1007/S00894-013-1876-Y  0.64
2012 Prokop JW, Duff RJ, Ball HC, Copeland DL, Londraville RL. Leptin and leptin receptor: analysis of a structure to function relationship in interaction and evolution from humans to fish. Peptides. 38: 326-36. PMID 23085324 DOI: 10.1016/J.Peptides.2012.10.002  0.41
2012 Prokop JW, Leeper TC, Duan ZH, Milsted A. Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domain. Bmc Bioinformatics. 13: S3. PMID 22536866 DOI: 10.1186/1471-2105-13-S2-S3  0.656
2012 Prokop JW, Watanabe IK, Turner ME, Underwood AC, Martins AS, Milsted A. From rat to human: regulation of Renin-Angiotensin system genes by sry. International Journal of Hypertension. 2012: 724240. PMID 22315667 DOI: 10.1155/2012/724240  0.665
2011 Turner ME, Ely D, Prokop J, Milsted A. Sry, more than testis determination? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R561-71. PMID 21677270 DOI: 10.1152/Ajpregu.00645.2010  0.615
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