| Year |
Citation |
Score |
| 2024 |
Chang M. Targeting Matrix Metalloproteinase-9 for Therapeutic Intervention in Diabetic Foot Ulcers. Acs Pharmacology & Translational Science. 7: 2901-2911. PMID 39421656 DOI: 10.1021/acsptsci.4c00263 |
0.314 |
|
| 2024 |
Nguyen VT, Birhanu BT, Miguel-Ruano V, Kim C, Batuecas M, Yang J, El-Araby AM, Jiménez-Faraco E, Schroeder VA, Alba A, Rana N, Sader S, Thomas CA, Feltzer R, Lee M, ... ... Chang M, et al. Restoring susceptibility to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus. Nature Chemical Biology. PMID 39060390 DOI: 10.1038/s41589-024-01688-0 |
0.448 |
|
| 2023 |
Qian Y, Birhanu BT, Yang J, Ding D, Janardhanan J, Mobashery S, Chang M. A Potent and Narrow-Spectrum Antibacterial against Infection. Journal of Medicinal Chemistry. PMID 37732641 DOI: 10.1021/acs.jmedchem.3c01249 |
0.459 |
|
| 2023 |
Janardhanan J, Kim C, Qian Y, Yang J, Meisel JE, Ding D, Speri E, Schroeder VA, Wolter WR, Oliver AG, Mobashery S, Chang M. A dual-action antibiotic that kills vegetative cells and inhibits spore germination. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304110120. PMID 37155891 DOI: 10.1073/pnas.2304110120 |
0.436 |
|
| 2023 |
Kim C, Lee M, Birhanu BH, Hesek D, Chang M, Mobashery S. Synthesis of Muramyl-δ-Lactam in Spore Peptidoglycan of Clostridioides difficile. Chembiochem : a European Journal of Chemical Biology. e202300282. PMID 37072375 DOI: 10.1002/cbic.202300282 |
0.392 |
|
| 2023 |
Chang M. Matrix metalloproteinase profiling and their roles in disease. Rsc Advances. 13: 6304-6316. PMID 36825288 DOI: 10.1039/d2ra07005g |
0.309 |
|
| 2022 |
Thakur V, Thakur VS, Aguila B, Slepak TI, Wang M, Song W, Konai M, Mobashery S, Chang M, Rana AB, Wang D, de Freitas JT, Humayun Gultekin S, Welford SM, Ivan ME, et al. Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation. Neuro-Oncology Advances. 4: vdac147. PMID 36212741 DOI: 10.1093/noajnl/vdac147 |
0.513 |
|
| 2022 |
Peng Z, Konai MM, Avila-Cobian LF, Wang M, Mobashery S, Chang M. MMP-1 and ADAM10 as Targets for Therapeutic Intervention in Idiopathic Pulmonary Fibrosis. Acs Pharmacology & Translational Science. 5: 548-554. PMID 35983283 DOI: 10.1021/acsptsci.2c00050 |
0.523 |
|
| 2022 |
Masitas C, Peng Z, Wang M, Konai MM, Avila-Cobian LF, Lemieux L, Hovanesian J, Grady JE, Mobashery S, Chang M. Matrix Metalloproteinase-14 as an Instigator of Fibrosis in Human Pterygium and Its Pharmacological Intervention. Acs Pharmacology & Translational Science. 5: 555-561. PMID 35983271 DOI: 10.1021/acsptsci.2c00125 |
0.549 |
|
| 2022 |
Peng Z, Nguyen TT, Wang M, Anderson B, Konai MM, Schroeder VA, Wolter WR, Page-Mayberry T, Peterson CE, Mobashery S, Chang M. Proteomics Identification of Targets for Intervention in Pressure Ulcers. Acs Chemical Biology. 17: 1357-1363. PMID 35670779 DOI: 10.1021/acschembio.2c00382 |
0.552 |
|
| 2021 |
Martínez-Caballero S, Mahasenan KV, Kim C, Molina R, Feltzer R, Lee M, Bouley R, Hesek D, Fisher JF, Muñoz IG, Chang M, Mobashery S, Hermoso JA. Integrative structural biology of the penicillin-binding protein-1 from , an essential component of the divisome machinery. Computational and Structural Biotechnology Journal. 19: 5392-5405. PMID 34667534 DOI: 10.1016/j.csbj.2021.09.018 |
0.408 |
|
| 2021 |
Kim C, Mahasenan KV, Bhardwaj A, Wiest O, Chang M, Mobashery S. Production of Proteins of the SARS-CoV-2 Proteome for Drug Discovery. Acs Omega. 6: 19983-19994. PMID 34337272 DOI: 10.1021/acsomega.1c02984 |
0.385 |
|
| 2021 |
Gabriel CER, Nguyen TT, Gargano EM, Fisher JF, Chang M, Mobashery S. Metabolism of the Selective Matrix Metalloproteinase-9 Inhibitor ()-ND-336. Acs Pharmacology & Translational Science. 4: 1204-1213. PMID 34151210 DOI: 10.1021/acsptsci.1c00063 |
0.504 |
|
| 2021 |
Speri E, Qian Y, Janardhanan J, Masitas C, Lastochkin E, De Benedetti S, Wang M, Schroeder VA, Wolter WR, Oliver AG, Fisher JF, Mobashery S, Chang M. Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target . Acs Medicinal Chemistry Letters. 12: 991-995. PMID 34141083 DOI: 10.1021/acsmedchemlett.1c00135 |
0.484 |
|
| 2021 |
Peng Z, Nguyen TT, Song W, Anderson B, Wolter WR, Schroeder VA, Hesek D, Lee M, Mobashery S, Chang M. Selective MMP-9 Inhibitor ()-ND-336 Alone or in Combination with Linezolid Accelerates Wound Healing in Infected Diabetic Mice. Acs Pharmacology & Translational Science. 4: 107-117. PMID 33615165 DOI: 10.1021/acsptsci.0c00104 |
0.559 |
|
| 2021 |
Chang M, Nguyen TT. Strategy for Treatment of Infected Diabetic Foot Ulcers. Accounts of Chemical Research. PMID 33596041 DOI: 10.1021/acs.accounts.0c00864 |
0.34 |
|
| 2021 |
Chang M, Mahasenan KV, Hermoso JA, Mobashery S. Unconventional Antibacterials and Adjuvants. Accounts of Chemical Research. PMID 33512995 DOI: 10.1021/acs.accounts.0c00776 |
0.483 |
|
| 2020 |
Marusak C, Thakur V, Li Y, Freitas JT, Zmina P, Chang M, Gao M, Tan J, Xiao M, Lu Y, Mills GB, Flaherty K, Frederick DT, Miao B, Sullivan RJ, et al. Targeting Extracellular Matrix Remodeling restores BRAF Inhibitor Sensitivity in BRAFi Resistant Melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32820016 DOI: 10.1158/1078-0432.Ccr-19-2773 |
0.41 |
|
| 2020 |
Speri E, Janardhanan J, Masitas C, Schroeder VA, Lastochkin E, Wolter WR, Fisher J, Mobashery S, Chang M. Discovery of a potent picolinamide antibacterial active against . Acs Infectious Diseases. PMID 32786277 DOI: 10.1021/Acsinfecdis.0C00479 |
0.515 |
|
| 2020 |
Nguyen TT, Wolter WR, Anderson B, Schroeder VA, Gao M, Gooyit M, Suckow MA, Chang M. Limitations of Knockout Mice and Other Tools in Assessment of the Involvement of Matrix Metalloproteinases in Wound Healing and the Means to Overcome Them. Acs Pharmacology & Translational Science. 3: 489-495. PMID 32566914 DOI: 10.1021/acsptsci.9b00109 |
0.754 |
|
| 2020 |
Qian Y, Allegretta G, Janardhanan J, Peng Z, Mahasenan KV, Lastochkin E, Gozun MMN, Tejera S, Schroeder VA, Wolter WR, Feltzer R, Mobashery S, Chang M. Exploration of the Structural Space in 4()-Quinazolinone Antibacterials. Journal of Medicinal Chemistry. PMID 32343145 DOI: 10.1021/Acs.Jmedchem.0C00153 |
0.529 |
|
| 2020 |
Boudreau MA, Ding D, Meisel JE, Janardhanan J, Spink E, Peng Z, Qian Y, Yamaguchi T, Testero SA, O'Daniel PI, Leemans E, Lastochkin E, Song W, Schroeder VA, Wolter WR, ... ... Chang M, et al. Structure-Activity Relationship for the Oxadiazole Class of Antibacterials. Acs Medicinal Chemistry Letters. 11: 322-326. PMID 32184964 DOI: 10.1021/Acsmedchemlett.9B00379 |
0.537 |
|
| 2019 |
Nguyen TT, Jones JI, Wolter WR, Pérez RL, Schroeder VA, Champion MM, Hesek D, Lee M, Suckow MA, Mobashery S, Chang M. Hyperbaric Oxygen Therapy Accelerates Wound Healing in Diabetic Mice by Decreasing Active Matrix Metalloproteinase-9. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. PMID 31736209 DOI: 10.1111/Wrr.12782 |
0.576 |
|
| 2019 |
Ceballos S, Kim C, Qian Y, Mobashery S, Chang M, Torres C. Susceptibility of methicillin-resistant to five quinazolinone antibacterials. Antimicrobial Agents and Chemotherapy. PMID 31611358 DOI: 10.1128/Aac.01344-19 |
0.501 |
|
| 2019 |
Rodriguez K, Howe E, Bacher E, Burnette M, Meloche J, Meisel J, Schnepp P, Tan X, Chang M, Zartman J, Zhang S, Ashfeld BL. Combined Scaffold Evaluation and Systems-level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes. Chemmedchem. PMID 31140738 DOI: 10.1002/Cmdc.201900266 |
0.316 |
|
| 2019 |
Jones JI, Nguyen TT, Peng Z, Chang M. Targeting MMP-9 in Diabetic Foot Ulcers. Pharmaceuticals (Basel, Switzerland). 12. PMID 31121851 DOI: 10.3390/Ph12020079 |
0.444 |
|
| 2019 |
Janardhanan J, Bouley R, Martínez-Caballero S, Peng Z, Batuecas-Mordillo M, Meisel JE, Ding D, Schroeder VA, Wolter WR, Mahasenan KV, Hermoso JA, Mobashery S, Chang M. The quinazolinone allosteric inhibitor of PBP2a synergizes with piperacillin and tazobactam against methicillin-resistant . Antimicrobial Agents and Chemotherapy. PMID 30858202 DOI: 10.1128/Aac.02637-18 |
0.54 |
|
| 2018 |
Raz L, Yang Y, Thompson J, Hobson S, Pesko J, Mobashery S, Chang M, Rosenberg G. MMP-9 inhibitors impair learning in spontaneously hypertensive rats. Plos One. 13: e0208357. PMID 30533010 DOI: 10.1371/Journal.Pone.0208357 |
0.557 |
|
| 2018 |
Andersson P, Yang Y, Hosaka K, Zhang Y, Fischer C, Braun H, Liu S, Yu G, Liu S, Beyaert R, Chang M, Li Q, Cao Y. Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis. Jci Insight. 3. PMID 30333314 DOI: 10.1172/Jci.Insight.122375 |
0.314 |
|
| 2018 |
Nguyen TT, Ding D, Wolter WR, Perez RL, Champion MM, Mahasenan KV, Hesek D, Lee M, Schroeder VA, Jones JI, Lastochkin E, Rose MK, Peterson CE, Suckow MA, Mobashery S, ... Chang M, et al. Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor that Accelerates Healing. Journal of Medicinal Chemistry. PMID 30212201 DOI: 10.1021/Acs.Jmedchem.8B01005 |
0.6 |
|
| 2018 |
Mahasenan KV, Ding D, Gao M, Nguyen TT, Suckow MA, Schroeder VA, Wolter WR, Chang M, Mobashery S. In Search of Selectivity in Inhibition of ADAM10. Acs Medicinal Chemistry Letters. 9: 708-713. PMID 30034605 DOI: 10.1021/Acsmedchemlett.8B00163 |
0.549 |
|
| 2018 |
Nguyen TT, Ding D, Wolter WR, Champion MM, Hesek D, Lee M, Pérez RL, Schroeder VA, Suckow MA, Mobashery S, Chang M. Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers. European Journal of Pharmacology. PMID 30012502 DOI: 10.1016/J.Ejphar.2018.07.014 |
0.561 |
|
| 2018 |
Chen S, Chen Z, Cui J, McCrary ML, Song H, Mobashery S, Chang M, Gu Z. Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice. Eneuro. 5. PMID 29963617 DOI: 10.1523/ENEURO.0391-17.2018 |
0.494 |
|
| 2018 |
Ceballos S, Kim C, Ding D, Mobashery S, Chang M, Torres C. Activities of oxadiazole antibacterials against and other Gram-positive bacteria. Antimicrobial Agents and Chemotherapy. PMID 29866865 DOI: 10.1128/Aac.00453-18 |
0.509 |
|
| 2017 |
Mahasenan KV, Bastian M, Gao M, Frost E, Ding D, Zorina-Lichtenwalter K, Jacobs J, Suckow MA, Schroeder VA, Wolter WR, Chang M, Mobashery S. Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases. Acs Medicinal Chemistry Letters. 8: 654-659. PMID 28626528 DOI: 10.1021/Acsmedchemlett.7B00130 |
0.586 |
|
| 2017 |
Meisel JE, Chang M. Selective Small-Molecule Inhibitors as Chemical Tools to Define the Roles of Matrix Metalloproteinases in Disease. Biochimica Et Biophysica Acta. PMID 28435009 DOI: 10.1016/J.Bbamcr.2017.04.011 |
0.456 |
|
| 2017 |
Mahasenan KV, Molina R, Bouley R, Batuecas MT, Fisher JF, Hermoso JA, Chang M, Mobashery S. Conformational dynamics in penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus, allosteric communication network and enablement of catalysis. Journal of the American Chemical Society. PMID 28099001 DOI: 10.1021/Jacs.6B12565 |
0.503 |
|
| 2016 |
Marusak C, Bayles I, Ma J, Gooyit M, Gao M, Chang M, Bedogni B. The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic dissemination. Pharmacological Research. PMID 27687955 DOI: 10.1016/J.Phrs.2016.09.033 |
0.77 |
|
| 2016 |
Gao M, Zhang H, Trivedi A, Mahasenan KV, Schroeder VA, Wolter WR, Suckow MA, Mobashery S, Noble-Haeusslein LJ, Chang M. Selective inhibition of MMP-2 does not alter neurological recovery after spinal cord injury. Acs Chemical Neuroscience. PMID 27551907 DOI: 10.1021/Acschemneuro.6B00217 |
0.552 |
|
| 2016 |
Janardhanan J, Meisel JE, Ding D, Schroeder VA, Wolter WR, Mobashery S, Chang M. In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams. Antimicrobial Agents and Chemotherapy. PMID 27401567 DOI: 10.1128/Aac.00787-16 |
0.502 |
|
| 2016 |
Janardhanan J, Chang M, Mobashery S. The oxadiazole antibacterials. Current Opinion in Microbiology. 33: 13-17. PMID 27239942 DOI: 10.1016/J.Mib.2016.05.009 |
0.523 |
|
| 2016 |
Bouley R, Ding D, Peng Z, Bastian M, Lastochkin E, Song W, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. Structure-Activity Relationship for the 4(3H)-Quinazolinone Antibacterials. Journal of Medicinal Chemistry. PMID 27088777 DOI: 10.1021/Acs.Jmedchem.6B00372 |
0.535 |
|
| 2016 |
Wang H, Hesek D, Lee M, Lastochkin E, Oliver AG, Chang M, Mobashery S. The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity. Journal of Natural Products. PMID 27049333 DOI: 10.1021/Acs.Jnatprod.6B00057 |
0.472 |
|
| 2016 |
Chang M. Restructuring of the extracellular matrix in diabetic wounds and healing: A perspective. Pharmacological Research. PMID 27033051 DOI: 10.1016/J.Phrs.2016.03.008 |
0.431 |
|
| 2016 |
Gooyit M, Peng Z, Mobashery S, Chang M. Chapter 10: Thiirane class of gelatinase inhibitors as a privileged template that crosses the blood-brain barrier Rsc Drug Discovery Series. 2016: 262-286. DOI: 10.1039/9781782622246-00262 |
0.741 |
|
| 2015 |
Leemans E, Mahasenan KV, Kumarasiri M, Spink E, Ding D, O'Daniel PI, Boudreau MA, Lastochkin E, Testero SA, Yamaguchi T, Lee M, Hesek D, Fisher JF, Chang M, Mobashery S. Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials. Bioorganic & Medicinal Chemistry Letters. PMID 26733473 DOI: 10.1016/J.Bmcl.2015.12.041 |
0.519 |
|
| 2015 |
Gao M, Nguyen TT, Suckow MA, Wolter WR, Gooyit M, Mobashery S, Chang M. Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598687 DOI: 10.1073/Pnas.1517847112 |
0.787 |
|
| 2015 |
Semple BD, Noble-Haeusslein LJ, Gooyit M, Tercovich KG, Peng Z, Nguyen TT, Schroeder VA, Suckow MA, Chang M, Raber J, Trivedi A. Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse. Plos One. 10: e0143386. PMID 26588471 DOI: 10.1371/Journal.Pone.0143386 |
0.749 |
|
| 2015 |
Gonzales PR, Pesesky MW, Bouley R, Ballard A, Biddy BA, Suckow MA, Wolter WR, Schroeder VA, Burnham CD, Mobashery S, Chang M, Dantas G. Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA. Nature Chemical Biology. 11: 855-861. PMID 26368589 DOI: 10.1038/Nchembio.1911 |
0.503 |
|
| 2015 |
Lee M, Chen Z, Tomlinson BN, Gooyit M, Hesek D, Juarez MR, Nizam R, Boggess B, Lastochkin E, Schroeder VA, Wolter WR, Suckow MA, Cui J, Mobashery S, Gu Z, ... Chang M, et al. Water-soluble MMP-9 inhibitor reduces lesion volume after severe traumatic brain injury. Acs Chemical Neuroscience. PMID 26241578 DOI: 10.1021/Acschemneuro.5B00140 |
0.793 |
|
| 2015 |
Ding D, Boudreau MA, Leemans E, Spink E, Yamaguchi T, Testero SA, O'Daniel PI, Lastochkin E, Chang M, Mobashery S. Exploration of the structure-activity relationship of 1,2,4-oxadiazole antibiotics. Bioorganic & Medicinal Chemistry Letters. PMID 26144346 DOI: 10.1016/J.Bmcl.2015.06.044 |
0.519 |
|
| 2015 |
Fishovitz J, Taghizadeh N, Fisher JF, Chang M, Mobashery S. The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA). Journal of the American Chemical Society. 137: 6500-5. PMID 25964995 DOI: 10.1021/Jacs.5B01374 |
0.503 |
|
| 2015 |
Wang H, Lee M, Peng Z, Blázquez B, Lastochkin E, Kumarasiri M, Bouley R, Chang M, Mobashery S. Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium. Journal of Medicinal Chemistry. 58: 4194-203. PMID 25923368 DOI: 10.1021/Jm501831G |
0.531 |
|
| 2015 |
Acebrón I, Chang M, Mobashery S, Hermoso JA. The Allosteric Site for the Nascent Cell Wall in Penicillin-Binding Protein 2a: An Achilles' Heel of Methicillin-Resistant Staphylococcus aureus. Current Medicinal Chemistry. 22: 1678-86. PMID 25760091 DOI: 10.2174/0929867322666150311150215 |
0.513 |
|
| 2015 |
Bouley R, Kumarasiri M, Peng Z, Otero LH, Song W, Suckow MA, Schroeder VA, Wolter WR, Lastochkin E, Antunes NT, Pi H, Vakulenko S, Hermoso JA, Chang M, Mobashery S. Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one. Journal of the American Chemical Society. 137: 1738-41. PMID 25629446 DOI: 10.1021/Jacs.5B00056 |
0.52 |
|
| 2015 |
Spink E, Ding D, Peng Z, Boudreau MA, Leemans E, Lastochkin E, Song W, Lichtenwalter K, O'Daniel PI, Testero SA, Pi H, Schroeder VA, Wolter WR, Antunes NT, Suckow MA, ... ... Chang M, et al. Structure-activity relationship for the oxadiazole class of antibiotics. Journal of Medicinal Chemistry. 58: 1380-9. PMID 25590813 DOI: 10.1021/Jm501661F |
0.522 |
|
| 2015 |
Gao M, Nguyen TT, Suckow MA, Wolter WR, Gooyit M, Mobashery S, Chang M. Acceleration of diabetic wound healing using a novel proteaseanti-protease combination therapy Proceedings of the National Academy of Sciences of the United States of America. 112: 15226-15231. DOI: 10.1073/pnas.1517847112/-/DCSupplemental |
0.733 |
|
| 2014 |
Xiao Q, Vakulenko S, Chang M, Mobashery S. Mutations in mmpL and in the cell wall stress stimulon contribute to resistance to oxadiazole antibiotics in methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 58: 5841-7. PMID 25049248 DOI: 10.1128/Aac.03501-14 |
0.486 |
|
| 2014 |
Fishovitz J, Hermoso JA, Chang M, Mobashery S. Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus. Iubmb Life. 66: 572-7. PMID 25044998 DOI: 10.1002/Iub.1289 |
0.495 |
|
| 2014 |
Fishovitz J, Rojas-Altuve A, Otero LH, Dawley M, Carrasco-López C, Chang M, Hermoso JA, Mobashery S. Disruption of allosteric response as an unprecedented mechanism of resistance to antibiotics. Journal of the American Chemical Society. 136: 9814-7. PMID 24955778 DOI: 10.1021/Ja5030657 |
0.521 |
|
| 2014 |
O'Daniel PI, Peng Z, Pi H, Testero SA, Ding D, Spink E, Leemans E, Boudreau MA, Yamaguchi T, Schroeder VA, Wolter WR, Llarrull LI, Song W, Lastochkin E, Kumarasiri M, ... ... Chang M, et al. Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity. Journal of the American Chemical Society. 136: 3664-72. PMID 24517363 DOI: 10.1021/Ja500053X |
0.523 |
|
| 2014 |
Gooyit M, Peng Z, Wolter WR, Pi H, Ding D, Hesek D, Lee M, Boggess B, Champion MM, Suckow MA, Mobashery S, Chang M. A chemical biological strategy to facilitate diabetic wound healing. Acs Chemical Biology. 9: 105-10. PMID 24053680 DOI: 10.1021/Cb4005468 |
0.794 |
|
| 2014 |
Ding D, Lichtenwalter K, Pi H, Mobashery S, Chang M. Characterization of a selective inhibitor for matrix metalloproteinase-8 (MMP-8) Medchemcomm. 5: 1381-1383. DOI: 10.1039/C4Md00172A |
0.61 |
|
| 2013 |
Hadass O, Tomlinson BN, Gooyit M, Chen S, Purdy JJ, Walker JM, Zhang C, Giritharan AB, Purnell W, Robinson CR, Shin D, Schroeder VA, Suckow MA, Simonyi A, Sun GY, ... ... Chang M, et al. Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury. Plos One. 8: e76904. PMID 24194849 DOI: 10.1371/Journal.Pone.0076904 |
0.783 |
|
| 2013 |
Otero LH, Rojas-Altuve A, Llarrull LI, Carrasco-López C, Kumarasiri M, Lastochkin E, Fishovitz J, Dawley M, Hesek D, Lee M, Johnson JW, Fisher JF, Chang M, Mobashery S, Hermoso JA. How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function. Proceedings of the National Academy of Sciences of the United States of America. 110: 16808-13. PMID 24085846 DOI: 10.1073/Pnas.1300118110 |
0.515 |
|
| 2013 |
Gooyit M, Song W, Mahasenan KV, Lichtenwalter K, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. O-phenyl carbamate and phenyl urea thiiranes as selective matrix metalloproteinase-2 inhibitors that cross the blood-brain barrier. Journal of Medicinal Chemistry. 56: 8139-50. PMID 24028490 DOI: 10.1021/Jm401217D |
0.785 |
|
| 2013 |
Smith CA, Antunes NT, Stewart NK, Toth M, Kumarasiri M, Chang M, Mobashery S, Vakulenko SB. Structural basis for carbapenemase activity of the OXA-23 β-lactamase from Acinetobacter baumannii. Chemistry & Biology. 20: 1107-15. PMID 24012371 DOI: 10.1016/J.Chembiol.2013.07.015 |
0.509 |
|
| 2013 |
Song W, Peng Z, Gooyit M, Suckow MA, Schroeder VA, Wolter WR, Lee M, Ikejiri M, Cui J, Gu Z, Chang M. Water-soluble mmp-9 inhibitor prodrug generates active metabolites that cross the blood-brain barrier. Acs Chemical Neuroscience. 4: 1168-73. PMID 23687970 DOI: 10.1021/Cn400077D |
0.75 |
|
| 2012 |
Gooyit M, Suckow MA, Schroeder VA, Wolter WR, Mobashery S, Chang M. Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier. Acs Chemical Neuroscience. 3: 730-6. PMID 23077716 DOI: 10.1021/Cn300062W |
0.776 |
|
| 2012 |
Makino H, Tada Y, Wada K, Liang EI, Chang M, Mobashery S, Kanematsu Y, Kurihara C, Palova E, Kanematsu M, Kitazato K, Hashimoto T. Pharmacological stabilization of intracranial aneurysms in mice: a feasibility study. Stroke; a Journal of Cerebral Circulation. 43: 2450-6. PMID 22798328 DOI: 10.1161/Strokeaha.112.659821 |
0.467 |
|
| 2012 |
Lee M, Ikejiri M, Klimpel D, Toth M, Espahbodi M, Hesek D, Forbes C, Kumarasiri M, Noll BC, Chang M, Mobashery S. Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors. Acs Medicinal Chemistry Letters. 3: 490-495. PMID 22737278 DOI: 10.1021/Ml300050B |
0.533 |
|
| 2012 |
Cui J, Chen S, Zhang C, Meng F, Wu W, Hu R, Hadass O, Lehmidi T, Blair GJ, Lee M, Chang M, Mobashery S, Sun GY, Gu Z. Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia. Molecular Neurodegeneration. 7: 21. PMID 22587708 DOI: 10.1186/1750-1326-7-21 |
0.575 |
|
| 2011 |
Testero SA, Llarrull LI, Fisher JF, Chang M, Mobashery S. Exploring the functional space of thiiranes as gelatinase inhibitors using click chemistry. Arkivoc : Free Online Journal of Organic Chemistry. 2011: 221-226. PMID 32774191 DOI: 10.3998/Ark.5550190.0012.719 |
0.585 |
|
| 2011 |
Testero SA, Lee M, Staran RT, Espahbodi M, Llarrull LI, Toth M, Mobashery S, Chang M. Sulfonate-containing thiiranes as selective gelatinase inhibitors. Acs Medicinal Chemistry Letters. 2: 177-81. PMID 24900296 DOI: 10.1021/Ml100254E |
0.607 |
|
| 2011 |
Gooyit M, Lee M, Schroeder VA, Ikejiri M, Suckow MA, Mobashery S, Chang M. Selective water-soluble gelatinase inhibitor prodrugs. Journal of Medicinal Chemistry. 54: 6676-90. PMID 21866961 DOI: 10.1021/Jm200566E |
0.762 |
|
| 2011 |
Zhang H, Chang M, Hansen CN, Basso DM, Noble-Haeusslein LJ. Role of matrix metalloproteinases and therapeutic benefits of their inhibition in spinal cord injury. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 8: 206-20. PMID 21455784 DOI: 10.1007/S13311-011-0038-0 |
0.386 |
|
| 2011 |
Testero SA, Bouley R, Fisher JF, Chang M, Mobashery S. Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases. Bioorganic & Medicinal Chemistry Letters. 21: 2675-8. PMID 21256011 DOI: 10.1016/J.Bmcl.2010.12.076 |
0.522 |
|
| 2011 |
Benson HL, Mobashery S, Chang M, Kheradmand F, Hong JS, Smith GN, Shilling RA, Wilkes DS. Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells. American Journal of Respiratory Cell and Molecular Biology. 44: 700-8. PMID 20639459 DOI: 10.1165/Rcmb.2010-0125Oc |
0.557 |
|
| 2009 |
Gooyit M, Lee M, Hesek D, Boggess B, Oliver AG, Fridman R, Mobashery S, Chang M. Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors. Chemical Biology & Drug Design. 74: 535-46. PMID 19824893 DOI: 10.1111/J.1747-0285.2009.00898.X |
0.798 |
|
| 2009 |
Ota R, Kurihara C, Tsou TL, Young WL, Yeghiazarians Y, Chang M, Mobashery S, Sakamoto A, Hashimoto T. Roles of matrix metalloproteinases in flow-induced outward vascular remodeling. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1547-58. PMID 19513084 DOI: 10.1038/Jcbfm.2009.77 |
0.547 |
|
| 2009 |
Lee M, Celenza G, Boggess B, Blase J, Shi Q, Toth M, Bernardo MM, Wolter WR, Suckow MA, Hesek D, Noll BC, Fridman R, Mobashery S, Chang M. A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition. Chemical Biology & Drug Design. 73: 189-202. PMID 19207421 DOI: 10.1111/J.1747-0285.2008.00750.X |
0.54 |
|
| 2008 |
Martin MD, Carter KJ, Jean-Philippe SR, Chang M, Mobashery S, Thiolloy S, Lynch CC, Matrisian LM, Fingleton B. Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background. Cancer Research. 68: 6251-9. PMID 18676849 DOI: 10.1158/0008-5472.Can-08-0537 |
0.578 |
|
| 2008 |
Celenza G, Villegas-Estrada A, Lee M, Boggess B, Forbes C, Wolter WR, Suckow MA, Mobashery S, Chang M. Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor. Chemical Biology & Drug Design. 71: 187-96. PMID 18221479 DOI: 10.1111/J.1747-0285.2008.00632.X |
0.511 |
|
| 2008 |
Kim DH, Lilliehook C, Roides B, Chen Z, Chang M, Mobashery S, Goldman SA. Testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 208-16. PMID 18171938 DOI: 10.1523/Jneurosci.3674-07.2008 |
0.564 |
|
| 2008 |
Lee M, Hesek D, Shi Q, Noll BC, Fisher JF, Chang M, Mobashery S. Conformational analyses of thiirane-based gelatinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3064-7. PMID 18083555 DOI: 10.1016/J.Bmcl.2007.11.131 |
0.532 |
|
| 2007 |
Lee M, Villegas-Estrada A, Celenza G, Boggess B, Toth M, Kreitinger G, Forbes C, Fridman R, Mobashery S, Chang M. Metabolism of a highly selective gelatinase inhibitor generates active metabolite. Chemical Biology & Drug Design. 70: 371-82. PMID 17927722 DOI: 10.1111/J.1747-0285.2007.00577.X |
0.597 |
|
| 2006 |
Bonfil RD, Sabbota A, Nabha S, Bernardo MM, Dong Z, Meng H, Yamamoto H, Chinni SR, Lim IT, Chang M, Filetti LC, Mobashery S, Cher ML, Fridman R. Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor. International Journal of Cancer. Journal International Du Cancer. 118: 2721-6. PMID 16381009 DOI: 10.1002/Ijc.21645 |
0.522 |
|
| 2005 |
Ikejiri M, Bernardo MM, Bonfil RD, Toth M, Chang M, Fridman R, Mobashery S. Potent mechanism-based inhibitors for matrix metalloproteinases. The Journal of Biological Chemistry. 280: 33992-4002. PMID 16046398 DOI: 10.1074/Jbc.M504303200 |
0.617 |
|
| 2005 |
Ikejiri M, Bernardo MM, Meroueh SO, Brown S, Chang M, Fridman R, Mobashery S. Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A. The Journal of Organic Chemistry. 70: 5709-12. PMID 15989356 DOI: 10.1021/Jo050339+ |
0.614 |
|
| 2005 |
Krüger A, Arlt MJ, Gerg M, Kopitz C, Bernardo MM, Chang M, Mobashery S, Fridman R. Antimetastatic activity of a novel mechanism-based gelatinase inhibitor. Cancer Research. 65: 3523-6. PMID 15867341 DOI: 10.1158/0008-5472.Can-04-3570 |
0.61 |
|
| 1992 |
Ikemoto N, Kim OK, Lo L, Satyanarayana V, Chang M, Nakanishi K. Ferric chloride, an anomerization catalyst for the preparation of alkyl α-glycopyranosides Tetrahedron Letters. 33: 4295-4298. DOI: 10.1016/S0040-4039(00)74242-0 |
0.37 |
|
| 1990 |
Fate G, Chang M, Lynn DG. Control of Germination in Striga asiatica: Chemistry of Spatial Definition. Plant Physiology. 93: 201-7. PMID 16667436 DOI: 10.1104/Pp.93.1.201 |
0.629 |
|
| 1990 |
Wiesler WT, Berova N, Ojika M, Meyers HV, Chang M, Zhou P, Lo L, Niwa M, Takeda R, Nakanishi K. A CD-Spectroscopic Alternative to Methylation Analysis of Oligosaccharides: Reference Spectra for Identification of Chromophoric Glycopyranoside Derivatives Helvetica Chimica Acta. 73: 509-551. DOI: 10.1002/Hlca.19900730302 |
0.373 |
|
| 1990 |
Lynn DG, Chang M. Phenolic signals in cohabitation: Implications for plant development Annual Review of Plant Physiology and Plant Molecular Biology. 41: 497-526. |
0.398 |
|
| 1989 |
Chang M, Nakanishi K, Meyers HV, Park MH, Takeda R, Ojika M, Hill J, Vázquez JT, Wiesler WT. Microscale structure determination of oligosaccharides by the exciton chirality method Pure and Applied Chemistry. 61: 1193-1200. DOI: 10.1351/Pac198961071193 |
0.382 |
|
| 1989 |
Ojika M, Meyers HV, Chang M, Nakanishi K. Microscale glycosidic cleavage of oligosaccharide bromobenzoates for circular dichroism analysis Journal of the American Chemical Society. 111: 8944-8946. DOI: 10.1021/Ja00206A042 |
0.362 |
|
| 1989 |
Chang M, Vazquez JT, Nakanishi K, Cataldo F, Estrada DM, Fernandez J, Gallardo A, Martin JD, Norte M, Perez R, Rodriguez ML. Regular and irregular sesquiterpenes containing a halogenated hydropyran from Laurencia caespitosa Phytochemistry. 28: 1417-1424. DOI: 10.1016/S0031-9422(00)97759-8 |
0.386 |
|
| 1988 |
Vazquez JT, Chang M, Nakanishi K, Martin JD, Martin VS, Perez R. Puertitols: novel sesquiterpenes from Laurencia obtusa. Structure elucidation and absolute configuration and conformation based on circular dichroism. Journal of Natural Products. 51: 1257-60. PMID 3236013 DOI: 10.1021/Np50060A036 |
0.402 |
|
| 1988 |
Vazquez JT, Chang M, Nakanishi K, Manta E, Perez C, Martin JD. Structure of hydroazulenoid diterpenes from a marine alga and their absolute configuration based on circular dichroism The Journal of Organic Chemistry. 53: 4797-4800. DOI: 10.1021/Jo00255A025 |
0.382 |
|
| 1986 |
Chang M, Lynn DG. The haustorium and the chemistry of host recognition in parasitic angiosperms. Journal of Chemical Ecology. 12: 561-79. PMID 24306796 DOI: 10.1007/Bf01020572 |
0.618 |
|
| 1986 |
Chang M, Netzly DH, Butler LG, Lynn DG. Chemical regulation of distance. Characterization of the first natural host germination stimulant for Striga asiatica. Journal of the American Chemical Society. 108: 7858-60. PMID 22283312 DOI: 10.1021/Ja00284A074 |
0.608 |
|
| 1986 |
Chang M, Netzly DH, Butler LG, Lynn DG. Chemical regulation of distance: Characterization of the first natural host germination stimulant for Striga asiatica Journal of the American Chemical Society. 108: 7858-7860. |
0.423 |
|
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